Nature Human Behaviour最新文献_第8页

I want universities to put breastfeeding on their gender pay gap agenda 我希望大学将母乳喂养列入性别薪酬差距议程

IF 21.4 1区心理学

Nature Human Behaviour Pub Date : 2024-07-04 DOI: 10.1038/s41562-024-01925-5

Ernestine Gheyoh Ndzi

引用次数: 0

Principled distillation of UK Biobank phenotype data reveals underlying structure in human variation 英国生物库表型数据的原理提炼揭示了人类变异的潜在结构

IF 21.4 1区心理学

Nature Human Behaviour Pub Date : 2024-07-04 DOI: 10.1038/s41562-024-01909-5

Caitlin E. Carey, Rebecca Shafee, Robbee Wedow, Amanda Elliott, Duncan S. Palmer, John Compitello, Masahiro Kanai, Liam Abbott, Patrick Schultz, Konrad J. Karczewski, Samuel C. Bryant, Caroline M. Cusick, Claire Churchhouse, Daniel P. Howrigan, Daniel King, George Davey Smith, Benjamin M. Neale, Raymond K. Walters, Elise B. Robinson

{"title":"Principled distillation of UK Biobank phenotype data reveals underlying structure in human variation","authors":"Caitlin E. Carey, Rebecca Shafee, Robbee Wedow, Amanda Elliott, Duncan S. Palmer, John Compitello, Masahiro Kanai, Liam Abbott, Patrick Schultz, Konrad J. Karczewski, Samuel C. Bryant, Caroline M. Cusick, Claire Churchhouse, Daniel P. Howrigan, Daniel King, George Davey Smith, Benjamin M. Neale, Raymond K. Walters, Elise B. Robinson","doi":"10.1038/s41562-024-01909-5","DOIUrl":"10.1038/s41562-024-01909-5","url":null,"abstract":"Data within biobanks capture broad yet detailed indices of human variation, but biobank-wide insights can be difficult to extract due to complexity and scale. Here, using large-scale factor analysis, we distill hundreds of variables (diagnoses, assessments and survey items) into 35 latent constructs, using data from unrelated individuals with predominantly estimated European genetic ancestry in UK Biobank. These factors recapitulate known disease classifications, disentangle elements of socioeconomic status, highlight the relevance of psychiatric constructs to health and improve measurement of pro-health behaviours. We go on to demonstrate the power of this approach to clarify genetic signal, enhance discovery and identify associations between underlying phenotypic structure and health outcomes. In building a deeper understanding of ways in which constructs such as socioeconomic status, trauma, or physical activity are structured in the dataset, we emphasize the importance of considering the interwoven nature of the human phenome when evaluating public health patterns. Carey and colleagues reveal 35 major latent constructs (factors) in the phenotype data of unrelated individuals with predominantly estimated European genetic ancestry from UK Biobank.","PeriodicalId":19074,"journal":{"name":"Nature Human Behaviour","volume":"8 8","pages":"1599-1615"},"PeriodicalIF":21.4,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41562-024-01909-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141521478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Why scientific integrity matters now more than ever 为什么科学诚信比以往任何时候都重要

IF 21.4 1区心理学

Nature Human Behaviour Pub Date : 2024-07-03 DOI: 10.1038/s41562-024-01913-9

Maria A. Caffrey

引用次数: 0

Author Correction: Standing up for the university 作者更正：为大学而战

IF 21.4 1区心理学

Nature Human Behaviour Pub Date : 2024-07-03 DOI: 10.1038/s41562-024-01937-1

Biray Kolluoglu, Lale Akarun

引用次数: 0

All STEM students should learn inclusive science communication 所有 STEM 学生都应学习包容性科学交流

IF 21.4 1区心理学

Nature Human Behaviour Pub Date : 2024-07-03 DOI: 10.1038/s41562-024-01918-4

Nicole C. Kelp, Ashley A. Anderson, Joy C. Enyinnaya

引用次数: 0

Identifying behaviour-related and physiological risk factors for suicide attempts in the UK Biobank 在英国生物库中识别自杀未遂的行为相关因素和生理风险因素

IF 21.4 1区心理学

Nature Human Behaviour Pub Date : 2024-07-02 DOI: 10.1038/s41562-024-01903-x

Bei Zhang, Jia You, Edmund T. Rolls, Xiang Wang, Jujiao Kang, Yuzhu Li, Ruohan Zhang, Wei Zhang, Huifu Wang, Shitong Xiang, Chun Shen, Yuchao Jiang, Chao Xie, Jintai Yu, Wei Cheng, Jianfeng Feng

{"title":"Identifying behaviour-related and physiological risk factors for suicide attempts in the UK Biobank","authors":"Bei Zhang, Jia You, Edmund T. Rolls, Xiang Wang, Jujiao Kang, Yuzhu Li, Ruohan Zhang, Wei Zhang, Huifu Wang, Shitong Xiang, Chun Shen, Yuchao Jiang, Chao Xie, Jintai Yu, Wei Cheng, Jianfeng Feng","doi":"10.1038/s41562-024-01903-x","DOIUrl":"10.1038/s41562-024-01903-x","url":null,"abstract":"Suicide is a global public health challenge, yet considerable uncertainty remains regarding the associations of both behaviour-related and physiological factors with suicide attempts (SA). Here we first estimated polygenic risk scores (PRS) for SA in 334,706 UK Biobank participants and conducted phenome-wide association analyses considering 2,291 factors. We identified 246 (63.07%) behaviour-related and 200 (10.41%, encompassing neuroimaging, blood and metabolic biomarkers, and proteins) physiological factors significantly associated with SA-PRS, with robust associations observed in lifestyle factors and mental health. Further case–control analyses involving 3,558 SA cases and 149,976 controls mirrored behaviour-related associations observed with SA-PRS. Moreover, Mendelian randomization analyses supported a potential causal effect of liability to 58 factors on SA, such as age at first intercourse, neuroticism, smoking, overall health rating and depression. Notably, machine-learning classification models based on behaviour-related factors exhibited high discriminative accuracy in distinguishing those with and without SA (area under the receiver operating characteristic curve 0.909 ± 0.006). This study provides comprehensive insights into diverse risk factors for SA, shedding light on potential avenues for targeted prevention and intervention strategies. This study reveals 246 behaviour-related and 200 physiological factors associated with genetic predisposition to suicide attempts. Mendelian randomization further indicates causal links for 58 factors.","PeriodicalId":19074,"journal":{"name":"Nature Human Behaviour","volume":"8 9","pages":"1784-1797"},"PeriodicalIF":21.4,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141489307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ethics committees promote responsible research in China 伦理委员会推动中国开展负责任的研究

IF 21.4 1区心理学

Nature Human Behaviour Pub Date : 2024-07-01 DOI: 10.1038/s41562-024-01917-5

Guoyu Wang

引用次数: 0

Archaeological evidence of an ethnographically documented Australian Aboriginal ritual dated to the last ice age 考古证据表明，有民族志记载的澳大利亚原住民仪式可追溯到上一个冰河时代。

IF 21.4 1区心理学

Nature Human Behaviour Pub Date : 2024-07-01 DOI: 10.1038/s41562-024-01912-w

Bruno David, Russell Mullett, Nathan Wright, Birgitta Stephenson, Jeremy Ash, Joanna Fresløv, GunaiKurnai Land and Waters Aboriginal Corporation, Jean-Jacques Delannoy, Matthew C. McDowell, Jerome Mialanes, Fiona Petchey, Lee J. Arnold, Ashleigh J. Rogers, Joe Crouch, Helen Green, Chris Urwin, Carney D. Matheson

{"title":"Archaeological evidence of an ethnographically documented Australian Aboriginal ritual dated to the last ice age","authors":"Bruno David, Russell Mullett, Nathan Wright, Birgitta Stephenson, Jeremy Ash, Joanna Fresløv, GunaiKurnai Land and Waters Aboriginal Corporation, Jean-Jacques Delannoy, Matthew C. McDowell, Jerome Mialanes, Fiona Petchey, Lee J. Arnold, Ashleigh J. Rogers, Joe Crouch, Helen Green, Chris Urwin, Carney D. Matheson","doi":"10.1038/s41562-024-01912-w","DOIUrl":"10.1038/s41562-024-01912-w","url":null,"abstract":"In societies without writing, ethnographically known rituals have rarely been tracked back archaeologically more than a few hundred years. At the invitation of GunaiKurnai Aboriginal Elders, we undertook archaeological excavations at Cloggs Cave in the foothills of the Australian Alps. In GunaiKurnai Country, caves were not used as residential places during the early colonial period (mid-nineteenth century CE), but as secluded retreats for the performance of rituals by Aboriginal medicine men and women known as ‘mulla-mullung’, as documented by ethnographers. Here we report the discovery of buried 11,000- and 12,000-year-old miniature fireplaces with protruding trimmed wooden artefacts made of Casuarina wood smeared with animal or human fat, matching the configuration and contents of GunaiKurnai ritual installations described in nineteenth-century ethnography. These findings represent 500 generations of cultural transmission of an ethnographically documented ritual practice that dates back to the end of the last ice age and that contains Australia’s oldest known wooden artefacts. Australian archaeological finds of 12,000-year-old fireplaces and artefacts match nineteenth-century GunaiKurnai ritual practices. They represent approximately 500 generations of cultural transmission of this ritual.","PeriodicalId":19074,"journal":{"name":"Nature Human Behaviour","volume":"8 8","pages":"1481-1492"},"PeriodicalIF":21.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41562-024-01912-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141477028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Twelve thousand years of ritual practice 一万两千年的仪式实践

IF 21.4 1区心理学

Nature Human Behaviour Pub Date : 2024-07-01 DOI: 10.1038/s41562-024-01916-6

Elspeth Hayes

引用次数: 0

A randomized controlled trial of nurse-led triage of 911 calls 由护士主导的 911 电话分流随机对照试验

IF 21.4 1区心理学

Nature Human Behaviour Pub Date : 2024-06-28 DOI: 10.1038/s41562-024-01890-z

引用次数: 0