Molecules最新文献_第5页

Gas Chromatography/Mass Spectrometry Chemical Profiling of Volatile Compounds from Cranberry Plant Byproducts as Potential Antibacterials, Antifungals, and Antioxidants. 蔓越莓植物副产物挥发性化合物作为潜在抗菌、抗真菌和抗氧化剂的气相色谱/质谱化学分析

IF 4.2 2区化学

Molecules Pub Date : 2025-05-04 DOI: 10.3390/molecules30092047

Martin Aborah, Frank Scarano, Catherine Neto

{"title":"Gas Chromatography/Mass Spectrometry Chemical Profiling of Volatile Compounds from Cranberry Plant Byproducts as Potential Antibacterials, Antifungals, and Antioxidants.","authors":"Martin Aborah, Frank Scarano, Catherine Neto","doi":"10.3390/molecules30092047","DOIUrl":"10.3390/molecules30092047","url":null,"abstract":"The increasing resistance of microorganisms to currently used antimicrobials requires the urgent development of new effective treatments. Plant-based natural products can be an alternative solution. The aerial plant parts of the cranberry (Vaccinium macrocarpon) present a potential new source of antimicrobial secondary metabolites. Volatile essential oils were extracted from Stevens, Early Black, and Mullica Queen variety plants by steam distillation (SD) and the Clevenger method (CM), and their profiles were characterized by GC-MS. The extracts and two identified constituents, cinnamaldehyde and terpineol, were screened by the disc diffusion assay against Gram-positive B. cereus ATCC 11778 and S. aureus ATCC 25923 and Gram-negative bacteria E. coli ATCC 25922, P. aeruginosa ATCC 27853, and C. albicans ATCC 14053. Radical scavenging antioxidant activity was also determined using the DPPH assay. The CM extracts were rich in fatty acids, sesquiterpenes, and diterpenes, whereas the SD extracts contained more aldehydes, monoterpenes, and phenylpropanoids. All volatile extracts showed promising antioxidant activity; leaf extract activity was significantly higher than the vine (p < 0.05). The CM leaf and vine extracts exhibited antimicrobial activity against B. cereus, S. aureus, E. coli, and C. albicans compared to the SD, and the leaf extracts were more effective than the vine extracts. Individual constituents of leaf and vine extracts, cinnamaldehyde and α-terpineol, also showed antimicrobial activity against these organisms. The active constituents of the CM extracts are yet to be identified. A multivariate analysis revealed a particular pattern of inhibition of the tested organisms. Based on our results, cranberry volatile extracts have potential for future valorization as antibacterials, antifungals, and antioxidants.","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 9","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12074010/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interfacial Synthesis of an Electro-Functional 2D Bis(terpyridine)copper(II) Polymer Nanosheet. 电功能二维双（三吡啶）铜（II）聚合物纳米片的界面合成。

IF 4.2 2区化学

Molecules Pub Date : 2025-05-04 DOI: 10.3390/molecules30092044

Kenji Takada, Joe Komeda, Hiroaki Maeda, Naoya Fukui, Hiroyasu Masunaga, Sono Sasaki, Hiroshi Nishihara

引用次数: 0

Chiral Pseudo-D_6h Dy(III) Single-Molecule Magnet Based on a Hexaaza Macrocycle. 基于六联体大环的手性伪d6h Dy（III）单分子磁体。

IF 4.2 2区化学

Molecules Pub Date : 2025-05-03 DOI: 10.3390/molecules30092043

Jia-Hui Liu, Yi-Shu Jin, Jinkui Tang, Cai-Ming Liu, Yi-Quan Zhang, Hui-Zhong Kou

{"title":"Chiral Pseudo-D6h Dy(III) Single-Molecule Magnet Based on a Hexaaza Macrocycle.","authors":"Jia-Hui Liu, Yi-Shu Jin, Jinkui Tang, Cai-Ming Liu, Yi-Quan Zhang, Hui-Zhong Kou","doi":"10.3390/molecules30092043","DOIUrl":"10.3390/molecules30092043","url":null,"abstract":"A mononuclear complex [Dy(phenN6)(HL')2]PF6·CH2Cl2 (H2L' = R/S-1,1'-binaphthyl-2,2'-diphenol) with local D6h symmetry was synthesized. Structural determination shows that Dy3+ was encapsulated within the coordination cavity of the neutral hexaaza macrocyclic ligand phenN6, forming a non-planar coordination environment. The axial positions are occupied by two phenoxy groups of binaphthol in the trans form. The local geometry of Dy3+ closely resembles a regular hexagonal bipyramid D6h configuration. The axial Dy-Ophenoxy distances are 2.189(5) and 2.145(5) Å, respectively, while the Dy-N bond lengths in the equatorial plane are in the range of 2.524(7)-2.717(5) Å. The axial Ophthalmoxy-Dy-Ophthalmoxy bond angle is 162.91(17)°, which deviates from the ideal linearity. Under the excitation at 320 nm, the complex exhibits a characteristic emission peak at 360 nm, corresponding to the naphthalene ring. The AC susceptibility measurements under an applied DC field of 1800 Oe show distinct temperature-dependent and frequency-dependent AC magnetic susceptibility, typical of single-molecule magnetic behavior. The Cole-Cole plot in the temperature range of 6.0-28.0 K was fitted using a model incorporating Orbach and Raman relaxation mechanisms, giving an effective energy barrier of Ueff = 300.2 K. Theoretical calculations on complex 1 reveal that the magnetization relaxation proceeds through the first excited Kramers doublets with a calculated magnetization blocking barrier of 404.1 cm-1 (581.4 K).","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 9","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12073781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analytical Method for the Simultaneous Determination of Albendazole and Metabolites Using HPLC-PDA: A Validation Study. HPLC-PDA同时测定阿苯达唑及其代谢物的分析方法：验证性研究。

IF 4.2 2区化学

Molecules Pub Date : 2025-05-03 DOI: 10.3390/molecules30092039

E Milena Vázquez, Beatriz Romero, Ana M Sahagún, Cristina López, Raúl de la Puente, José M Rodríguez, Nélida Fernández, M José Diez, Raquel Díez

{"title":"Analytical Method for the Simultaneous Determination of Albendazole and Metabolites Using HPLC-PDA: A Validation Study.","authors":"E Milena Vázquez, Beatriz Romero, Ana M Sahagún, Cristina López, Raúl de la Puente, José M Rodríguez, Nélida Fernández, M José Diez, Raquel Díez","doi":"10.3390/molecules30092039","DOIUrl":"10.3390/molecules30092039","url":null,"abstract":"Albendazole is an anthelmintic drug commonly used in animals and humans against nematodes. A sensitive, accurate, precise, and time-saving high-performance liquid chromatography (HPLC) method for the simultaneous determination of albendazole and metabolites (albendazole sulfoxide and albendazole sulfone) in cattle plasma has been developed and validated. A solid-phase extraction (SPE) was carried out. Separation was performed with an XBridge® C18 column (4.6 mm × 250 mm, 5 µm) with gradient elution of acetonitrile:ammonium acetate buffer 0.025 M with pH adjusted to 6.6. The flow rate was 1.2 mL/min, and the PDA detector was set at 292 nm. Calibration curves were linear in the range from 0.025 to 2.0 µg/mL for the three compounds evaluated, with correlation coefficients ≥ 0.99. For the lower limit of quantification (LLOQ), within- and between-run precision and accuracy were satisfactory, with coefficients of variation (CV) ≤ 15.1% and deviations ≤ 117.7%, respectively. The method fulfilled all validation criteria established by the European Medicines Agency guideline (EMA/CHMP/ICH/172948/2019).","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 9","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12073153/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Selected Polyphenols of Polish Poplar Propolis as a Key Component Shaping Its Antibacterial Properties-In Vitro and In Silico Approaches. 波兰杨树蜂胶中的多酚类物质是其抗菌性能的关键组成部分——体外和硅法研究。

IF 4.2 2区化学

Molecules Pub Date : 2025-05-03 DOI: 10.3390/molecules30092036

Małgorzata Dżugan, Michał Miłek, Ewa Ciszkowicz, Andrzej Łyskowski, Monika Tomczyk

{"title":"Selected Polyphenols of Polish Poplar Propolis as a Key Component Shaping Its Antibacterial Properties-In Vitro and In Silico Approaches.","authors":"Małgorzata Dżugan, Michał Miłek, Ewa Ciszkowicz, Andrzej Łyskowski, Monika Tomczyk","doi":"10.3390/molecules30092036","DOIUrl":"10.3390/molecules30092036","url":null,"abstract":"Propolis is a natural antibacterial medicine with a varied content of phenolic compounds, which determines the activity of the ethanol extract of propolis (EEP). A new attempt was made to standardize ethanol propolis extract via its conversion into a dry concentrate (dEEP) through a two-step process. Four samples of poplar propolis from the same geographical region were used for the study. Obtained dry concentrates reconstituted in 70% ethanol (500 μg/mL) were analyzed for their antioxidant properties, total phenolic and flavonoid contents, as well as HPLC polyphenol profile. It was shown that dEEP solutions in 70% ethanol, regardless of the diversified quality of the raw material, have equalized antioxidant properties and phenolic and flavonoid contents compared to raw EEPs. However, quantitative differences in the nine individual components were still found by HPLC-DAD. The antibacterial activity of the dEEP solutions (0.03-500 µg/mL) was compared with three individual polyphenols' effect against Klebsiella pneumoniae and Streptococcus agalactiae. Based on the obtained MIC values and anti-biofilm activity of dEEPs compared to pure polyphenols, it was established that the effectiveness of the extract results from the combined action of flavonoids and phenolic acids. The antibacterial effectiveness of p-coumaric acid, galangin, and pinocembrin was additionally modeled using in silico analyses, suggesting promiscuous binding of all tested polyphenolic ligands to target enzymes.","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 9","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12073398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Liquid Carbon-Boron Cluster Additives for Mixed Amine-50. 混合胺-50用液态碳硼团簇添加剂。

IF 4.2 2区化学

Molecules Pub Date : 2025-05-03 DOI: 10.3390/molecules30092037

Xiaogang Mu, Shenghui Wang, Fanzhi Yang, Hao Li

{"title":"Liquid Carbon-Boron Cluster Additives for Mixed Amine-50.","authors":"Xiaogang Mu, Shenghui Wang, Fanzhi Yang, Hao Li","doi":"10.3390/molecules30092037","DOIUrl":"10.3390/molecules30092037","url":null,"abstract":"Boron-containing compounds, known for their high calorific value, can significantly enhance the energy density of traditional liquid propellants. Through precise chemical modification of the C-H bonds in ortho-carborane, a novel liquid cluster material was synthesized: C,C'-Bis(2-ethylhexanoylmethyl)-o-carborane (BEHMC). This compound exhibits excellent stability, density, and energy properties. By combining BEHMC with mixed amine-50, a cluster liquid propellant was formulated, and its key performance metrics such as density, freezing point, mass calorific value, and volumetric calorific value were evaluated. The propellant achieved a density of 0.884 g·cm-3, a freezing point below -55 °C, a mass calorific value of 41.13 kJ·g-1, and a volumetric calorific value of 36.36 kJ·cm-3. The theoretical specific impulse reached 346 s, and the theoretical density impulse was 2.99 × 106 N·s·m-3. Compared to the traditional mixed amine-50/red fuming nitric acid propellant, the cluster liquid propellant developed in this study maintains a similar calorific value while improving the theoretical specific impulse and density impulse by 2.3% and 3.8%, respectively.","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 9","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12073575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Temperature Regulation Efficiency of a Bilayer Coating on Glass with Evaporative and Radiative Cooling for Energy Management. 能量管理用蒸发和辐射冷却双层玻璃涂层的温度调节效率评价。

IF 4.2 2区化学

Molecules Pub Date : 2025-05-03 DOI: 10.3390/molecules30092042

Huanying Zhang, Yonghang Yu, Dedong Ji, Chen Zhou, Shengyang Yang

{"title":"Evaluation of Temperature Regulation Efficiency of a Bilayer Coating on Glass with Evaporative and Radiative Cooling for Energy Management.","authors":"Huanying Zhang, Yonghang Yu, Dedong Ji, Chen Zhou, Shengyang Yang","doi":"10.3390/molecules30092042","DOIUrl":"10.3390/molecules30092042","url":null,"abstract":"With the increasing demand for energy-efficient and sustainable building materials, innovative cooling technologies have become a key focus in the construction industry. This study developed a double-layer cooling coating integrating evaporation and radiation mechanisms. The first layer consists of a TiO2/PUA radiation layer, where rutile TiO2 is incorporated into polyurethane acrylate (PUA) resin to enhance solar reflectivity. The second layer is a P(NVP-co-NMA) hydrogel, which evaporates water at high temperatures and absorbs moisture from the air at low temperatures, eliminating the need for additional water supply systems. The TiO2/PUA@P(NVP-co-NMA) coating demonstrates high solar reflectivity and infrared emissivity, effectively reducing indoor temperatures by dissipating heat through water evaporation and radiative cooling. Testing showed a temperature reduction of approximately 7.6 °C in a small house with this coating under simulated conditions. This material demonstrates favorable properties that may make it suitable for applications on building roofs and exterior walls, potentially addressing some limitations of conventional evaporative or radiative cooling systems. Its observed multi-effect cooling performance indicates promise for contributing to energy savings in sustainable building designs.","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 9","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12073255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stereoselectivity of In Vivo Processes and Bioactivity of Farrerol Enantiomers. 法瑞罗对映体体内过程的立体选择性及生物活性。

IF 4.2 2区化学

Molecules Pub Date : 2025-05-03 DOI: 10.3390/molecules30092038

Lirong Chen, Tang Yan, Dongting Huang, Wei Xu, Yongjing Liu, Xiaoying Wang, Hua Li

{"title":"Stereoselectivity of In Vivo Processes and Bioactivity of Farrerol Enantiomers.","authors":"Lirong Chen, Tang Yan, Dongting Huang, Wei Xu, Yongjing Liu, Xiaoying Wang, Hua Li","doi":"10.3390/molecules30092038","DOIUrl":"10.3390/molecules30092038","url":null,"abstract":"Farrerol, a bioactive compound found in Folium Rhododendri daurici, demonstrates various biological and pharmacological effects. Nevertheless, the stereoselectivity of in vivo processes and bioactivity between its enantiomers have not been thoroughly investigated. This study aimed to explore the stereoselectivity and pharmacological activity variations in farrerol enantiomers, focusing on stereoselective pharmacokinetics, tissue distribution, in vitro metabolism using liver microsomes, in vivo intestinal absorption, molecular simulations of binding affinity with antiproliferative target, and cell viability assessed through the CCK-8 assay. The findings indicated that the pharmacokinetic characteristics of farrerol in rats' plasma, liver, and kidney tissues displayed enantioselectivity after intragastric administration. Then, no chiral transformation between farrerol enantiomers was observed in the rat plasma when (+)-farrerol and (-)-farrerol were orally administered. Additionally, there are notable stereoselective differences in the inhibition of CYP 1A2, CYP 2C9, CYP 2C19, and CYP 3A4/5 enzymes by (+)-farrerol and (-)-farrerol (p < 0.01). These differences may contribute to the stereoselectivity observed in the hepatic metabolism of the two enantiomers of farrerol. In addition, there were selective differences in the binding of farrerol enantiomers to anti-proliferative targets, including UCHL3, STAT3β, PTP1B, and GSK3β. Farrerol enantiomers exhibited similar growth inhibitory effects in HT-29 cell. Overall, our work will provide a solid theoretical basis and experimental reference for the further development and utilization of farrerol enantiomers.","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 9","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12073438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Single-Step Upcycling of Sugarcane Bagasse and Iron Scrap into Magnetic Carbon for High-Performance Adsorbents. 蔗渣和废铁单步回收制备高性能吸附剂磁性碳。

IF 4.2 2区化学

Molecules Pub Date : 2025-05-03 DOI: 10.3390/molecules30092040

Sirinad Mahawong, Piyatida Thaveemas, Parichart Onsri, Sulawan Kaowphong, Waralee Watcharin, Supanna Techasakul, Decha Dechtrirat, Laemthong Chuenchom

{"title":"Single-Step Upcycling of Sugarcane Bagasse and Iron Scrap into Magnetic Carbon for High-Performance Adsorbents.","authors":"Sirinad Mahawong, Piyatida Thaveemas, Parichart Onsri, Sulawan Kaowphong, Waralee Watcharin, Supanna Techasakul, Decha Dechtrirat, Laemthong Chuenchom","doi":"10.3390/molecules30092040","DOIUrl":"10.3390/molecules30092040","url":null,"abstract":"The sugar industry produces significant quantities of waste biomass, while other industrial sectors generate iron scrap as waste. This study seeks to make use of these waste products using an in situ approach that integrates carbonization, activation, and magnetization to convert sugarcane waste and iron scrap into a magnetic carbon composite adsorbent. The porosity of the activated carbon was enhanced by the activating agent potassium hydroxide (KOH) and further improved by the addition of iron scrap, which also imparted magnetic properties to the composite. The developed porosity of the composite increased the overall adsorption capacity of the adsorbent. The synthesis conditions were varied to examine the effects on the properties of the adsorbent. The amount of KOH used in the synthesis influenced the performance of the material. The best-performing adsorbent demonstrated strong potential in the treatment of wastewater by exhibiting an adsorption capacity of 1736.93 mg/g for the antibiotic tetracycline. The magnetic properties of the composite adsorbent enable simple separation and recovery, making the adsorbent reusable and lowering operating costs. This study provides a clear framework for the synthesis of waste-derived magnetic carbon composite adsorbents that can offer financial and environmental advantages while remaining effective in industrial contexts.","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 9","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12073645/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chlorine Dioxide (ClO₂)-Releasing Sachet for Preservation of Cherry Tomatoes. 保存圣女果的二氧化氯（ClO2）释放香囊。

IF 4.2 2区化学

Molecules Pub Date : 2025-05-03 DOI: 10.3390/molecules30092041

Junseok Lee, Hojun Shin, Kambiz Sadeghi, Jongchul Seo

{"title":"Chlorine Dioxide (ClO2)-Releasing Sachet for Preservation of Cherry Tomatoes.","authors":"Junseok Lee, Hojun Shin, Kambiz Sadeghi, Jongchul Seo","doi":"10.3390/molecules30092041","DOIUrl":"10.3390/molecules30092041","url":null,"abstract":"Chlorine dioxide (ClO2) is a powerful sterilizing agent that is widely used to prevent the spoilage of fresh foods during delivery and storage. However, its practical applications are hindered by a short sterilization duration, complex deployment processes, and high treatment costs. To address these challenges, an innovative ClO2 self-releasing sachet was developed, which was specifically designed for use in retail and wholesale markets. The sachet utilizes polyether block amide (PEBAX®) as a hydrophilic polymer to facilitate the dissociation of sodium chlorite (NaClO2) and citric acid (CA), which generates ClO2. A PEBAX/CA composite film was coated onto kraft paper to construct the sachet. This design extended the ClO2 release period to over 3 d, with a controllable release rate being achieved by adjusting the concentrations of NaClO2 and CA. In practical tests, the sachets inhibited fungal growth by >50% over 14 d at 20 °C within a corrugated box. Furthermore, they preserved the quality of the cherry tomatoes for 16 d during storage. These results demonstrate that the newly developed sachet offers an economical and user-friendly solution for fresh-food packaging, effectively preserving product quality.","PeriodicalId":19041,"journal":{"name":"Molecules","volume":"30 9","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12073356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0