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Identification of genetic factors of type 2 diabetes mellitus risk in South Asian populations 确定南亚人群 2 型糖尿病风险的遗传因素
IF 31 1区 医学
Nature Reviews Endocrinology Pub Date : 2024-12-17 DOI: 10.1038/s41574-024-01082-9
Olivia Tysoe
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引用次数: 0
From the perspective of a scientist with Cushing disease, what did not kill me made my science stronger 从一个患有库欣病的科学家的角度来看，没有杀死我的东西让我的科学更强大
IF 31 1区 医学
Nature Reviews Endocrinology Pub Date : 2024-12-17 DOI: 10.1038/s41574-024-01080-x
Yana Zavros
{"title":"From the perspective of a scientist with Cushing disease, what did not kill me made my science stronger","authors":"Yana Zavros","doi":"10.1038/s41574-024-01080-x","DOIUrl":"10.1038/s41574-024-01080-x","url":null,"abstract":"Research siloes slow the translation of scientific discovery to patient care and limit progress in improving treatments for Cushing disease to incremental advances. Facilitating collaborative efforts that study the complexity of pituitary neuroendocrine tumours would advance the development of targeted treatments for patients who experience a low quality of life for years owing to this rare and understudied disease.","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"21 3","pages":"131-132"},"PeriodicalIF":31.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142831962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Publisher Correction: Growth hormone-releasing hormone and its analogues in health and disease 出版商更正：健康与疾病中的生长激素释放激素及其类似物
IF 31 1区 医学
Nature Reviews Endocrinology Pub Date : 2024-12-16 DOI: 10.1038/s41574-024-01081-w
Riccarda Granata, Sheila Leone, Xianyang Zhang, Iacopo Gesmundo, Charlotte Steenblock, Renzhi Cai, Wei Sha, Ezio Ghigo, Joshua M. Hare, Stefan R. Bornstein, Andrew V. Schally
{"title":"Publisher Correction: Growth hormone-releasing hormone and its analogues in health and disease","authors":"Riccarda Granata, Sheila Leone, Xianyang Zhang, Iacopo Gesmundo, Charlotte Steenblock, Renzhi Cai, Wei Sha, Ezio Ghigo, Joshua M. Hare, Stefan R. Bornstein, Andrew V. Schally","doi":"10.1038/s41574-024-01081-w","DOIUrl":"10.1038/s41574-024-01081-w","url":null,"abstract":"","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"21 3","pages":"196-196"},"PeriodicalIF":31.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41574-024-01081-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142825495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in appetite regulation by the arcuate nucleus 弓形核食欲调节的研究进展
IF 31 1区 医学
Nature Reviews Endocrinology Pub Date : 2024-12-13 DOI: 10.1038/s41574-024-01079-4
Cristina Garcia-Caceres
{"title":"Advances in appetite regulation by the arcuate nucleus","authors":"Cristina Garcia-Caceres","doi":"10.1038/s41574-024-01079-4","DOIUrl":"10.1038/s41574-024-01079-4","url":null,"abstract":"In 2024, new insights identified a cluster of leptin-targeted neurons and integrative networks that link sensory inputs (heat and food perception) with feeding centres and peripheral systems. Key findings revealed hypothalamic site-specific adaptive mechanisms, in which nutritional state-dependent remodelling of extracellular compounds and neuropeptide transmission calibrate appetite via the arcuate nucleus.","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"21 2","pages":"71-72"},"PeriodicalIF":31.0,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intermittent and periodic fasting in the treatment of obesity and type 2 diabetes mellitus 间歇性和周期性禁食治疗肥胖和2型糖尿病
IF 31 1区 医学
Nature Reviews Endocrinology Pub Date : 2024-12-13 DOI: 10.1038/s41574-024-01078-5
Valter D. Longo
{"title":"Intermittent and periodic fasting in the treatment of obesity and type 2 diabetes mellitus","authors":"Valter D. Longo","doi":"10.1038/s41574-024-01078-5","DOIUrl":"10.1038/s41574-024-01078-5","url":null,"abstract":"Several new clinical studies provide evidence for the potential of specific intermittent and periodic fasting interventions to decrease adiposity and HbA1c in patients with obesity and/or type 2 diabetes mellitus, while also reducing drug use, adverse effects and risk factors for other diseases.","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"21 2","pages":"73-74"},"PeriodicalIF":31.0,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surveying the landscape of emerging osteoanabolic therapies 调查新兴骨合成代谢疗法的前景
IF 31 1区 医学
Nature Reviews Endocrinology Pub Date : 2024-12-09 DOI: 10.1038/s41574-024-01076-7
Thomas H. Ambrosi
{"title":"Surveying the landscape of emerging osteoanabolic therapies","authors":"Thomas H. Ambrosi","doi":"10.1038/s41574-024-01076-7","DOIUrl":"10.1038/s41574-024-01076-7","url":null,"abstract":"Established antiresorptive treatments for osteoporosis only slow down bone loss, and available osteoanabolic therapies — although more effective — have broad limitations. Recent insights into sex-specific systemic regulation of skeletal mass, an enhanced understanding of the cellular complexity of bone marrow and innovative options such as senolytics have fuelled the development of potentially transformative bone anabolic treatments.","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"21 2","pages":"75-76"},"PeriodicalIF":31.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142793383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in cardiometabolic outcomes in polycystic ovary syndrome 多囊卵巢综合征心脏代谢结局的研究进展
IF 31 1区 医学
Nature Reviews Endocrinology Pub Date : 2024-12-04 DOI: 10.1038/s41574-024-01072-x
Lisa J. Moran
{"title":"Advances in cardiometabolic outcomes in polycystic ovary syndrome","authors":"Lisa J. Moran","doi":"10.1038/s41574-024-01072-x","DOIUrl":"10.1038/s41574-024-01072-x","url":null,"abstract":"The year 2024 brought continuing research in the crucial field of adiposity-related health and polycystic ovary syndrome (PCOS). Although PCOS is considered a heterogeneous condition with regards to diagnostic criteria, complications and management, current research is advancing our understanding of the presentation and metabolic features of PCOS, as well as the benefits of lifestyle management.","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"21 2","pages":"67-68"},"PeriodicalIF":31.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142763241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in basic biology and translation in islet research 基础生物学与胰岛研究进展
IF 31 1区 医学
Nature Reviews Endocrinology Pub Date : 2024-12-04 DOI: 10.1038/s41574-024-01073-w
Carmella Evans-Molina
{"title":"Advances in basic biology and translation in islet research","authors":"Carmella Evans-Molina","doi":"10.1038/s41574-024-01073-w","DOIUrl":"10.1038/s41574-024-01073-w","url":null,"abstract":"Advances in islet cell biology over the past few years highlight a fundamental role for intra-islet endocrine cell interactions and δ-cells in the regulation of glycaemia. New insights into how cellular heterogeneity and individual-level heterogeneity effect hormone secretion have also emerged.","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"21 2","pages":"69-70"},"PeriodicalIF":31.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142763243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Memory of obesity stored in adipocytes 肥胖的记忆储存在脂肪细胞中
IF 31 1区 医学
Nature Reviews Endocrinology Pub Date : 2024-12-03 DOI: 10.1038/s41574-024-01070-z
Claire Greenhill
{"title":"Memory of obesity stored in adipocytes","authors":"Claire Greenhill","doi":"10.1038/s41574-024-01070-z","DOIUrl":"10.1038/s41574-024-01070-z","url":null,"abstract":"","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"21 2","pages":"64-64"},"PeriodicalIF":31.0,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142760538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Opposing neuropeptides control cAMP signalling to regulate satiety 对立神经肽控制cAMP信号以调节饱腹感
IF 31 1区 医学
Nature Reviews Endocrinology Pub Date : 2024-11-29 DOI: 10.1038/s41574-024-01068-7
Senegal Carty
{"title":"Opposing neuropeptides control cAMP signalling to regulate satiety","authors":"Senegal Carty","doi":"10.1038/s41574-024-01068-7","DOIUrl":"10.1038/s41574-024-01068-7","url":null,"abstract":"","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"21 2","pages":"63-63"},"PeriodicalIF":31.0,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142742405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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