发布求助
文献互助 智能选刊 最新文献

Nature Reviews Endocrinology最新文献

筛选
英文 中文
Emerging applications of human iPSCs in pituitary diseases. 人类多能干细胞在垂体疾病中的新应用。
IF 40.5 1区 医学
Nature Reviews Endocrinology Pub Date : 2026-03-26 DOI: 10.1038/s41574-026-01248-7
Ryusaku Matsumoto,Keitaro Kanie,Yutaka Takahashi
{"title":"Emerging applications of human iPSCs in pituitary diseases.","authors":"Ryusaku Matsumoto,Keitaro Kanie,Yutaka Takahashi","doi":"10.1038/s41574-026-01248-7","DOIUrl":"https://doi.org/10.1038/s41574-026-01248-7","url":null,"abstract":"","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"15 1","pages":""},"PeriodicalIF":40.5,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147518479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors, management and consequences of severe menopausal vasomotor symptoms 严重绝经期血管舒缩症状的危险因素、管理和后果
IF 40.5 1区 医学
Nature Reviews Endocrinology Pub Date : 2026-03-25 DOI: 10.1038/s41574-026-01245-w
Martha Hickey, Annabelle Huguenin, Hsin-Fang Chung, Gita D. Mishra
{"title":"Risk factors, management and consequences of severe menopausal vasomotor symptoms","authors":"Martha Hickey, Annabelle Huguenin, Hsin-Fang Chung, Gita D. Mishra","doi":"10.1038/s41574-026-01245-w","DOIUrl":"https://doi.org/10.1038/s41574-026-01245-w","url":null,"abstract":"","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"44 1","pages":""},"PeriodicalIF":40.5,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147506744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The link between heat exposure and gestational diabetes mellitus 热暴露与妊娠期糖尿病之间的联系。
IF 4 1区 医学
Nature Reviews Endocrinology Pub Date : 2026-03-23 DOI: 10.1038/s41574-026-01246-9
Senegal Carty
{"title":"The link between heat exposure and gestational diabetes mellitus","authors":"Senegal Carty","doi":"10.1038/s41574-026-01246-9","DOIUrl":"10.1038/s41574-026-01246-9","url":null,"abstract":"","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"22 5","pages":"261-261"},"PeriodicalIF":40.0,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147502405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Greater recognition required for thyroid disorders 甲状腺疾病需要更多的认识。
IF 4 1区 医学
Nature Reviews Endocrinology Pub Date : 2026-03-17 DOI: 10.1038/s41574-026-01237-w
{"title":"Greater recognition required for thyroid disorders","authors":"","doi":"10.1038/s41574-026-01237-w","DOIUrl":"10.1038/s41574-026-01237-w","url":null,"abstract":"Thyroid dysfunction contributes to increased morbidity and mortality of major non-communicable diseases but is given little attention as a public health priority. This Focus issue aims to raise awareness of thyroid dysfunction and its wide-reaching health burden.","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"22 4","pages":"193-193"},"PeriodicalIF":40.0,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41574-026-01237-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147471549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dysfunctional adipose tissue-lymphatic crosstalk in obesity. 肥胖症中功能失调的脂肪组织-淋巴串扰。
IF 40.5 1区 医学
Nature Reviews Endocrinology Pub Date : 2026-03-16 DOI: 10.1038/s41574-026-01243-y
William De Nardo,Andrea Y Chan,Christopher J H Porter,Enyuan Cao,Natalie L Trevaskis
{"title":"Dysfunctional adipose tissue-lymphatic crosstalk in obesity.","authors":"William De Nardo,Andrea Y Chan,Christopher J H Porter,Enyuan Cao,Natalie L Trevaskis","doi":"10.1038/s41574-026-01243-y","DOIUrl":"https://doi.org/10.1038/s41574-026-01243-y","url":null,"abstract":"The lymphatic vasculature is recognized for its roles in immunity, lipid transport and fluid homeostasis, but has been ignored, until recently, for its involvement in adipose tissue metabolism, obesity and associated comorbidities. States of overnutrition, such as in obesity, are associated with impairment of lymphatic function, leading to localized lymphoedema, adipogenesis and insulin resistance. Conversely, compromised lymphatic vasculature integrity can induce adiposity and accelerate insulin resistance. Through the use of advanced 'omics' and bioinformatic technologies coupled with functional experiments in cells, mice and humans, we now know that the lymphatic system is more than just a transport conduit and is intimately involved in tissue and organ homeostasis, including in adipose tissue. In this Review, we summarize the interconnected causes of obesity and lymphatic dysfunction with a particular focus on delineating the underappreciated yet fundamental crosstalk between the lymphatic network and white and brown adipose tissues. We also synthesize information on lymph-directed therapeutic strategies that have the potential to transform outcomes in obesity.","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"52 1","pages":""},"PeriodicalIF":40.5,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147465232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peritumoural adipose tissue protects colorectal cancer from immune attack 肿瘤周围脂肪组织保护结直肠癌免受免疫攻击。
IF 4 1区 医学
Nature Reviews Endocrinology Pub Date : 2026-03-11 DOI: 10.1038/s41574-026-01244-x
Olivia Tysoe
{"title":"Peritumoural adipose tissue protects colorectal cancer from immune attack","authors":"Olivia Tysoe","doi":"10.1038/s41574-026-01244-x","DOIUrl":"10.1038/s41574-026-01244-x","url":null,"abstract":"","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"22 5","pages":"259-259"},"PeriodicalIF":40.0,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147393838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Living with type 1 diabetes mellitus with Black heritage: my personal journey 生活与1型糖尿病与黑人遗产：我的个人旅程。
IF 4 1区 医学
Nature Reviews Endocrinology Pub Date : 2026-03-09 DOI: 10.1038/s41574-026-01242-z
Daniel Newman
{"title":"Living with type 1 diabetes mellitus with Black heritage: my personal journey","authors":"Daniel Newman","doi":"10.1038/s41574-026-01242-z","DOIUrl":"10.1038/s41574-026-01242-z","url":null,"abstract":"For nearly three decades, my life has consisted of insulin injections, monitoring of glucose levels and emotional, mental and physical labour. Here, I share my experience of being a Black person living with type 1 diabetes mellitus, including cultural and systemic challenges that affected my access to the care I was entitled to.","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"22 5","pages":"255-256"},"PeriodicalIF":40.0,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147381320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperinsulinaemia as a cause of obesity and cardiometabolic diseases. 高胰岛素血症是肥胖和心脏代谢疾病的原因。
IF 40.5 1区 医学
Nature Reviews Endocrinology Pub Date : 2026-03-09 DOI: 10.1038/s41574-026-01240-1
Nicola Guess,James D Johnson,Allan Vaag,Abd A Tahrani,Barbara Corkey,Jennifer E Bruin,Jon P Little
{"title":"Hyperinsulinaemia as a cause of obesity and cardiometabolic diseases.","authors":"Nicola Guess,James D Johnson,Allan Vaag,Abd A Tahrani,Barbara Corkey,Jennifer E Bruin,Jon P Little","doi":"10.1038/s41574-026-01240-1","DOIUrl":"https://doi.org/10.1038/s41574-026-01240-1","url":null,"abstract":"This narrative Review explores the role of hyperinsulinaemia as a potential independent contributor to obesity and cardiometabolic diseases. We argue that scientific discussions about the role of hyperinsulinaemia as a causal factor in these conditions have not sufficiently distinguished between postprandial insulin excursions and chronically elevated basal levels of insulin. We summarize findings from observational and experimental human trials, as well as preclinical models, and outline how reasonable evidence suggests that chronic (basal) exposure to elevated levels of insulin, rather than normal postprandial insulin excursions in isolation, might have a role in promoting or exacerbating the development of adiposity. We discuss the putative contributors to hyperinsulinaemia, including genetic predisposition, early-life influences, diet, environmental pollutants and physical inactivity, highlighting causality knowledge gaps relevant to the prevention of obesity and cardiometabolic diseases.","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"47 1","pages":""},"PeriodicalIF":40.5,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147381319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The gut microbiome and ageing trajectories: mechanisms and clinical implications. 肠道微生物组和衰老轨迹：机制和临床意义。
IF 40.5 1区 医学
Nature Reviews Endocrinology Pub Date : 2026-03-03 DOI: 10.1038/s41574-026-01236-x
Andrea Ticinesi,Stefania Maggi,Antonio Nouvenne,Giovanni Zuliani,Claudio Franceschi
{"title":"The gut microbiome and ageing trajectories: mechanisms and clinical implications.","authors":"Andrea Ticinesi,Stefania Maggi,Antonio Nouvenne,Giovanni Zuliani,Claudio Franceschi","doi":"10.1038/s41574-026-01236-x","DOIUrl":"https://doi.org/10.1038/s41574-026-01236-x","url":null,"abstract":"This Review discusses the current state of knowledge on the contribution of the gut microbiome as a potential key actor in defining how we age. The gut microbiome is a complex ecosystem that establishes lifelong dynamic interactions with the host at multiple levels (several gut-organ axes), differently influencing ageing patterns and age-related disease onset and progression across populations. Accordingly, the definition of a 'normative' gut microbiome remains elusive, depending largely on the interaction with the external environment. In this complex scenario, the causal role of the gut microbiome in defining the ageing trajectory and its precise contribution to various organ-specific age-related diseases is still uncertain in clinical terms and could be context specific. Multiparametric and uniqueness indexes within a given population have shown a certain capacity for predicting disability and mortality. However, the gut microbiome is shaped over time by exposure to different intrinsic and environmental factors, resulting in a high degree of inter-individual variability, a key phenomenon that should be considered to develop novel personalized strategies to counteract age-related disease and frailty.","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"52 1","pages":""},"PeriodicalIF":40.5,"publicationDate":"2026-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147346368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dual benefits of HIF activation HIF激活的双重好处。
IF 4 1区 医学
Nature Reviews Endocrinology Pub Date : 2026-02-27 DOI: 10.1038/s41574-026-01241-0
Claire Greenhill
{"title":"Dual benefits of HIF activation","authors":"Claire Greenhill","doi":"10.1038/s41574-026-01241-0","DOIUrl":"10.1038/s41574-026-01241-0","url":null,"abstract":"","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"22 5","pages":"260-260"},"PeriodicalIF":40.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147317798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信
小红书