Nanoscale Advances最新文献

{"title":"Modulations of the work function and morphology of a single MoS2 nanotube by charge injection†","authors":"Maja Remškar, Janez Jelenc, Nikolai Czepurnyi, Matjaž Malok, Luka Pirker, Rupert Schreiner and Andreas K. Hüttel","doi":"10.1039/D4NA00490F","DOIUrl":"10.1039/D4NA00490F","url":null,"abstract":"<p >Both the miniaturization of transistor components and the ongoing investigation of material systems with potential for quantum information processing have significantly increased current interest of researchers in semiconducting inorganic nanotubes. Here we report on an additional outstanding aspect of these nanostructures, namely the intrinsic coupling of electronic and mechanical properties. We observe electronic and morphology changes in a single MoS<small>₂</small> nanotube, exposed to charge injections by means of an atomic-force-microscopy tip. An elliptic deformation of the nanotube and helical twisting of the nanotube are visible, consistent with the reverse piezoelectric effect. Work-function changes are found to be dependent on the polarity of the injected carriers. An unexpected long-term persistence of the shape deformations is observed and explained with accumulation of structural defects and the resultant strain, which could cause a memory-like charge confinement and a long lasting modulation of the work function.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":null,"pages":null},"PeriodicalIF":4.6,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/na/d4na00490f?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141743420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atomically dispersed Pt1Ir1 pair for synergetic hydrogenation of levulinic acid to γ-valerolactone","authors":"Boyang Liu, Lin-Wei Chen, Lei Wang","doi":"10.1039/d4na00419a","DOIUrl":"https://doi.org/10.1039/d4na00419a","url":null,"abstract":"Atomically dispersed metal catalysts have attracted numerous attentions in various important reaction due to the high atom utilization and specific coordination environment. However, the monometallic single sites sometimes presented undesirable catalytic performance, which usually need the synergistic effect with the neighboring metal atoms, such as dimers or trimers. Different metal pairs on various solid carrier have been reported, nonetheless, huge challenges remain to precisely prepare metal pair-site. Here, we presented a versatile strategy to synthesized atomically Pt1Ir1 pair via the strong metal-sulfur interaction over the porous sulfur-doped carbons. The Pt1Ir1 pair sites presented high activity and stability for hydrogenation of levulinic acid to γ-valerolactone.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141743532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficient siRNA delivery to murine melanoma cells via a novel genipin-based nano-polymer†","authors":"Giulia Della Pelle, Tim Bozic, Marija Vukomanović, Gregor Sersa, Bostjan Markelc and Nina Kostevšek","doi":"10.1039/D4NA00363B","DOIUrl":"10.1039/D4NA00363B","url":null,"abstract":"<p >Small-interfering RNAs (siRNAs) are therapeutic nucleic acids, often delivered <em>via</em> cationic polymers, liposomes, or extracellular vesicles, each method with its limitations. Genipin, a natural crosslinker for primary amines, was explored for siRNA delivery scaffolds. Spermine/genipin-based G<em>x</em>S5 polymers were synthesized, showing slightly positive <em>ζ</em> potential at neutral pH and intrinsic fluorescence. We then tuned their polymerization adding glycine to the reaction batch, from 1 to 10 molar ratio with genipin, therefore conferring them a “zwitterionic” character. G<em>x</em>S5 efficiently internalized into B16F10 murine melanoma cells, and exhibited strong siRNA-complexing ability and they were able to elicit up to 60% of gene knock-down without any toxicity. This highlights G<em>x</em>S5's potential as a safe, replicable, and tunable platform for therapeutic nucleic acid delivery, suggesting broader applications. This innovative approach not only sheds light on the intricate genipin reaction mechanism but also underscores the importance of fine-tuning nanoparticle properties for effective siRNA delivery. G<em>x</em>S5's success in mitigating cytotoxicity while maintaining delivery efficacy signifies a promising step towards safer and more efficient nucleic acid therapeutics.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":null,"pages":null},"PeriodicalIF":4.6,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/na/d4na00363b?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141743530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chiral porphyrin-SiO2 nano helices-based sensors for vapor enantiomers recognition†","authors":"Ilaria Di Filippo, Zakaria Anfar, Gabriele Magna, Piyanan Pranee, Donato Monti, Manuela Stefanelli, Reiko Oda, Corrado Di Natale and Roberto Paolesse","doi":"10.1039/D4NA00217B","DOIUrl":"10.1039/D4NA00217B","url":null,"abstract":"<p >The ability of olfaction to distinguish odors is based on many different properties deriving from the molecular structure, including chirality. Even if the electronic nose (e-nose) concept has been widely used in strict analogy with biological systems to implement sensor arrays that recognize and distinguish complex odor matrices, the fabrication of an enantioselective e-nose remains a challenge. This paper introduces an array of quartz microbalances (QMB) functionalized with sensitive materials made of a combination of achiral receptors and silica nanohelices grafted by chiral and achiral porphyrins. In this combination, nanohelices provide a chiral template for the spatial arrangement of porphyrins, while porphyrins act as receptors that can interact differently with analytes. Remarkably, even if single sensors show scarce enantioselectivity, the signals of the overall array achieve recognition of the chiral identity of the five diverse enantiomeric pairs tested when the data are processed with proper multivariate algorithms. Such an innovative and generalizable approach is expected to enable the formation of an extensive library of readily integrable chiral receptors in enantioselective sensor arrays, potentially revolutionizing diverse fields such as agrochemicals, medicine, and environmental sciences.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":null,"pages":null},"PeriodicalIF":4.6,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/na/d4na00217b?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141743529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scalable DNA recognition circuits based on DNA strand displacement","authors":"Fang Wang, Beiyu Shi, Ying Chen, Xiaolong Shi, Zheng Kou, Xiao-Li Qiang","doi":"10.1039/d4na00379a","DOIUrl":"https://doi.org/10.1039/d4na00379a","url":null,"abstract":"DNA is a kind of nano-molecule considered to be computable on the molecular level, and the precise Watson-Crick principle of base pairing has made it possible for DNA to be a novel computer material. The DNA strand displacement technology has greatly facilitated the development of DNA computing in both logical and intelligent computation. In this paper, we proposed and implemented a molecular recognition circuit based on DNA strand displacement, which can achieve recognition and summation functions. This circuit has a simple molecular composition and is easily scalable. A cross-inhalation module was integrated based upon the molecular recognition circuit to construct a molecular comparator. Considering the advantages of modularity and the experimental feasibility of scalable recognition circuit, it could be used as pattern signal recognition and classification module in smart molecular circuits or biosensors.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141743534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Yield Seedless Synthesis of Mini Gold Nanorods: Partial Silver Decoupling Enabling Effective Nanorods Elongation With Tunable Surface Plasmon Resonance Beyond 1000 nm and CTAB-Free Functional Coating for mTHPC Conjugation","authors":"Mike Rozenberg, Matěj Bárta, Anya Muzikansky, Melina Zysler, Karolina Siskova, Yitzhak Mastai, David Zitoun","doi":"10.1039/d4na00507d","DOIUrl":"https://doi.org/10.1039/d4na00507d","url":null,"abstract":"Gold nanorods with reduced dimensions possess better cellular uptake and absorption efficiency. The ability to synthesize gold nanorods while maintaining tunability of the aspect ratio towards an increased value is challenging, as it requires careful control of the reaction conditions, often employing additional parameters such as pH modification or the use of polymeric additives. We demonstrate a seedless approach for the synthesis of mini (width&lt;10 nm) gold nanorods with tunable longitudinal surface plasmon resonance from ~700 nm to &gt;1000 nm with aspect ratios ranging from ~3 to ~7 without the use of any polymeric additives or pH modification. A single mild reduction agent, hydroquinone, allows for up to ~98% reaction yield from the gold precursor. A mechanism for the elongation is proposed based on partial silver decoupling from the reaction. Finally, the particles are coated with various capping agents to allow functionalization and conjugation of mTHPC drug molecules used in photodynamic treatments and the cytotoxic CTAB is removed to increase their biocompatibility.","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141743535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimization and scalability assessment of supercapacitor electrodes based on hydrothermally grown MoS2 on carbon cloth†","authors":"Jasna Mannayil, Olli Pitkänen, Minna Mannerkorpi and Krisztian Kordas","doi":"10.1039/D4NA00368C","DOIUrl":"10.1039/D4NA00368C","url":null,"abstract":"<p >MoS<small>₂</small> is a well-known 2D transition metal dichalcogenide (TMD) with feasibility for energy storage applications due to its eco-friendliness and high electroactive surface area. Electrodes based on MoS<small>₂</small> are typically made by either immobilizing its multiphase nanocomposites, having binders and conductive fillers, or by directly growing the materials on current collectors. In this work, we follow and optimize this latter approach by applying a hydrothermal route to directly synthesize MoS<small>₂</small> nanostructures on carbon cloth (MoS<small>₂</small>@CC) hence enabling binder-free current collector electrodes. Raman spectroscopy and electron microscopy analyses confirmed the formation of 2H MoS<small>₂</small> nanosheets with hexagonal structure. The as-prepared electrodes were used to assemble symmetric supercapacitor cells, whose performance were tested in various types of electrolytes. Electrochemical measurements indicate that both precursor concentration and growth time significantly affect the device performance. Under optimized conditions, specific capacitance up to 226 F g<small>⁻¹</small> (at 1 A g<small>⁻¹</small> in 6 M KOH) was achieved, with corresponding energy and power densities of 5.1 W h kg<small>⁻¹</small> and 2.1 W kg<small>⁻¹</small>. The device showed good stability, retaining 85% capacitance after 1000 cycles. Furthermore, the electrodes assessed in PYR14-TFSI showed energy and power densities of up to 26.3 W h kg<small>⁻¹</small> and 2.0 kW kg<small>⁻¹</small>, respectively, indicating their feasibility not only in aqueous but also in ionic liquid electrolytes. In addition, galvanostatic charge/discharge measurements conducted on devices having footprint sizes from 1 cm<small>²</small> to 25 cm<small>²</small> show very similar specific capacitances, which proves scalability and thus the practical relevance of the binder-free electrodes demonstrated in this study.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":null,"pages":null},"PeriodicalIF":4.6,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/na/d4na00368c?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141743536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of different flexible substrates on the photothermal reduction quality of graphene oxide†","authors":"Matheus Guitti Bonando, Gabriel Monte Mór Moreira, Nathália Maria Moraes Fernandes, David Steinberg, Alisson Ronieri Cadore, Cecília de Carvalho Castro Silva and Lúcia Akemi Miyazato Saito","doi":"10.1039/D4NA00385C","DOIUrl":"10.1039/D4NA00385C","url":null,"abstract":"<p >In this work, we demonstrate the impact of the photothermal reduction quality of graphene oxide (GO), which is affected by the material composition, roughness, and thermal properties of the membrane substrates. We show high efficiency reduced graphene oxide (rGO) conversion by applying a 405 nm pulsed laser in ambient conditions onto different flexible substrates. Three filter membranes, such as nylon, cellulose acetate, and nitrocellulose, are used as rGO thin film substrates, achieving sheet resistance of 51 ± 2, 58 ± 3, and 620 ± 40 Ω sq<small>⁻¹</small>, respectively, which has been the lowest resistance reported in ambient conditions. Finally, we demonstrate that such flexible materials can be applied as temperature sensors ranging from 35 °C to 100 °C. The best sensitivity is achieved using nylon membranes, showing a smoother rGO surface and lower defect density.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":null,"pages":null},"PeriodicalIF":4.6,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/na/d4na00385c?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141743538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic antioxidant and antibacterial effects of a Zn-ascorbate metal–organic framework loaded with marjoram essential oil†","authors":"Rana R. Haikal, Noha El Salakawy, Alaa Ibrahim, Shaimaa L. Ali and Wael Mamdouh","doi":"10.1039/D4NA00519H","DOIUrl":"10.1039/D4NA00519H","url":null,"abstract":"<p >Antimicrobial resistance (AMR) has become an immense threat to public health leading to an urgent need for development of new technologies to tackle such a challenge. Plant-based drugs, specifically essential oils (EOs) and plant extracts, have shown significant potential as effective green antimicrobial agents. However, they suffer from high volatility and low thermal stability resulting in their inefficient utilization in commercial settings. Among the various nanoencapsulation technologies reported, metal–organic frameworks (MOFs) have been recently investigated as potential nanocarriers of EOs in attempt to enhance their stability. Herein, we report the utilization of Zn-ascorbate MOF for the encapsulation of marjoram essential oil (MEO) with synergistic antioxidant and antibacterial activities. The prepared composite was thoroughly characterized <em>via</em> a number of techniques and its antibacterial performance was investigated against various strains of Gram-negative and Gram-positive bacteria. The results demonstrated that the antioxidant activity originated from the ascorbic acid ligand (<small>L</small>-Asc), while the antibacterial activity originated from Zn<small>²⁺</small> ions as well as encapsulated MEO.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":null,"pages":null},"PeriodicalIF":4.6,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/na/d4na00519h?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141718644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fair surface modification with mixed alkanethiols on gold nanoparticles through minimal unfair ligand exchange†","authors":"Kun Xiong, Masaharu Nagayama, Kuniharu Ijiro and Hideyuki Mitomo","doi":"10.1039/D4NA00270A","DOIUrl":"10.1039/D4NA00270A","url":null,"abstract":"<p >Surface modification with functional molecules is essential for introducing various surface properties. As gold nanoparticles (AuNPs) have extraordinary chemical, physical, and optical properties, control of their surface, mainly through modification with mixed alkanethiols <em>via</em> Au–S interactions, has attracted much attention. However, surface modification of AuNPs with mixed alkanethiols to provide a strictly regulated composition remains challenging. Further, there are very few methods that can easily establish the nature of ligands and their replacement with similar molecules at nanoparticle surfaces, limiting precise analyses. Herein, we demonstrate an unfair ligand exchange between oligo(ethylene glycol) (OEG)-attached alkanethiols as a source of unfair surface modification utilizing programable thermo-responsive properties of OEG-alkanethiols-modified AuNPs and fair surface modification with mixed OEG-alkanethiols by minimizing this effect. OEG-alkanethiols-modified AuNPs show an assembly/disassembly behavior in response to the solution temperature. Assembly temperature (<em>T</em><small>_A</small>) changes in the presence of other OEG-alkanethiols, confirming the ligand exchange between alkanethiols in an aqueous solution. Kinetic analyses indicate that the competitive exchange reaction of these two alkanethiols results in an unfair ligand exchange, which leads to gradual changes in surface composition. As this ligand exchange between alkanethiols takes a longer time compared to that from citric acid, which initially covered the AuNPs, exact surface modification of AuNPs with OEG-alkanethiols is performed by moderate reaction conditions (25 °C, several to 24 hours). This insight regarding “more prolonged reaction is not always better” could be widely applied for surface modifications with various thiol-ligands.</p>","PeriodicalId":18806,"journal":{"name":"Nanoscale Advances","volume":null,"pages":null},"PeriodicalIF":4.6,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/na/d4na00270a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141718640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}