NanoImpact最新文献_第2页

Nano versus bulk: Evaluating the toxicity of lanthanum, yttrium, and cerium oxides on Enchytraeus crypticus 纳米与体积：评估镧、钇和铈氧化物对隐斑斑腹虫的毒性。

IF 4.7 3区环境科学与生态学

NanoImpact Pub Date : 2025-01-01 DOI: 10.1016/j.impact.2024.100540

Joana Santos , Inês Neca , Ana Capitão , João Nogueira , José A.S. Santos , Edgar Pinto , Angela Barreto , Ana L. Daniel-da-Silva , Vera L. Maria

{"title":"Nano versus bulk: Evaluating the toxicity of lanthanum, yttrium, and cerium oxides on Enchytraeus crypticus","authors":"Joana Santos , Inês Neca , Ana Capitão , João Nogueira , José A.S. Santos , Edgar Pinto , Angela Barreto , Ana L. Daniel-da-Silva , Vera L. Maria","doi":"10.1016/j.impact.2024.100540","DOIUrl":"10.1016/j.impact.2024.100540","url":null,"abstract":"<div><div>Considering the increase in demand for rare earth elements (REEs) and their accumulation in soil ecosystems, it is crucial to understand their toxicity. However, the impact of lanthanum, yttrium and cerium oxides (La<sub>2</sub>O<sub>3</sub>, Y<sub>2</sub>O<sub>3</sub> and CeO<sub>2</sub>, respectively) on soil organisms remains insufficiently studied. This study aims to unravel the effects of La<sub>2</sub>O<sub>3</sub>, Y<sub>2</sub>O<sub>3</sub> and CeO<sub>2</sub> nanoparticles (NPs) and their corresponding bulk forms (0, 156, 313, 625, 1250 and 2500 mg/kg) on the terrestrial species <em>Enchytraeus crypticus</em>. The effects on survival, reproduction (21 days (d)), avoidance behavior (2 d) and DNA integrity (2 and 7 d) of <em>E. crypticus</em> were evaluated. No significant effects on survival were observed. For La<sub>2</sub>O<sub>3</sub>, the bulk form affected more endpoints than the NPs, inducing avoidance behavior (1250 mg/kg) and DNA damage (1250 mg/kg - 2 d; 2500 mg/kg - 7 d). The Y<sub>2</sub>O<sub>3</sub> NPs demonstrated higher toxicity than the bulk form: decreased reproduction (≥ 1250 mg/kg); induced avoidance behavior (≥ 625 mg/kg) and DNA damage (≥ 156 mg/kg - 2 d; 2500 mg/kg - 7 d). For CeO<sub>2</sub>, both forms exhibited similar toxicity, decreasing reproduction (625 mg/kg for bulk and 2500 mg/kg for NPs) and inducing DNA damage at all tested concentrations for both forms. REEs oxides toxicity was influenced by the REEs type and concentration, exposure time and material form, suggesting different modes of action. This study highlights the distinct responses of <em>E. crypticus</em> after exposure to REEs oxides and shows that REEs exposure may differently affect soil organisms, emphasizing the importance of risk assessment.</div></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"37 ","pages":"Article 100540"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142895806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mixtures of polystyrene micro and nanoplastics affects fat and glucose metabolism in 3T3-L1 adipocytes and zebrafish larvae

IF 4.7 3区环境科学与生态学

NanoImpact Pub Date : 2025-01-01 DOI: 10.1016/j.impact.2025.100549

Jung Eun Kim , Narayan Sah Sonar , Laxmi Sen Thakuri , Jin Woo Park , Ki-Tae Kim , Dong Young Rhyu

{"title":"Mixtures of polystyrene micro and nanoplastics affects fat and glucose metabolism in 3T3-L1 adipocytes and zebrafish larvae","authors":"Jung Eun Kim , Narayan Sah Sonar , Laxmi Sen Thakuri , Jin Woo Park , Ki-Tae Kim , Dong Young Rhyu","doi":"10.1016/j.impact.2025.100549","DOIUrl":"10.1016/j.impact.2025.100549","url":null,"abstract":"<div><div>Microplastics (MPs) and nanoplastics (NPs) are pervasive pollutants that pose a hazard to human health. Although most previous studies have investigated the effects of MPs and NPs on digestion, oxidative stress, and inflammation in diverse models, the combined effect of plastic mixtures (PM) containing MPs and NPs on obesity and type 2 diabetes mellitus (T2DM) remains unknown. The hypothesis of our study is to verify the association between PM exposure and clinical features of metabolic diseases such as lipogenesis and insulin resistance. Therefore, we investigated the effects of PM on fat and glucose metabolism in 3T3-L1 cells and high-fat diet (HFD)-induced zebrafish larvae. PM exposure increased cell viability, differentiation, adipogenesis (<em>PPARγ</em> and <em>C/EBPα</em>), and lipogenesis (<em>FAS</em> and <em>SREBP-1c</em>), while it decreased glucose uptake and inhibited insulin signal (<em>IRS1</em>, <em>PI3K</em>, <em>AKT,</em> and <em>GLUT4</em>) expression 3T3-L1 cells. In zebrafish larvae, PM mainly bioaccumulated in the intestine and pancreatic tissue, reducing glucose uptake and increasing body weight and blood glucose compared to controls. Moreover, PM significantly increased adipogenic differentiation (<em>PPARγ</em>) and synthesis (<em>FASN</em> and <em>FABP</em>), proinflammatory cytokines (<em>TNF-α</em> and <em>IL-6</em>), and gluconeogenesis (<em>PCK1</em> and <em>G6Pase</em>). Conversely, energy and fat metabolism (<em>AMPKα</em> and <em>adiponectin</em>), insulin production (<em>INSα</em>), signaling pathway (<em>IRS1</em>, <em>AKT,</em> and <em>GLUT2</em>), and anti-inflammatory cytokines (<em>IL-10</em> and <em>IL-4</em>) were suppressed. Overall, this study sheds light on the mechanisms responsible for the detrimental effects of PM exposure on fat and glucose metabolism, providing insights into metabolic disorders, like type 2 diabetes, in both in vitro and in vivo models.</div></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"37 ","pages":"Article 100549"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolomics reveals the toxicity of polystyrene nanoplastics in the gills of Acrossocheilus yunnanensis

IF 4.7 3区环境科学与生态学

NanoImpact Pub Date : 2025-01-01 DOI: 10.1016/j.impact.2025.100552

Qianqian Xiang , Ruisi Yang , Zexiang Hua , Peng Wang , Jilai Zhang , Wenyu Long , Xuexiu Chang

{"title":"Metabolomics reveals the toxicity of polystyrene nanoplastics in the gills of Acrossocheilus yunnanensis","authors":"Qianqian Xiang , Ruisi Yang , Zexiang Hua , Peng Wang , Jilai Zhang , Wenyu Long , Xuexiu Chang","doi":"10.1016/j.impact.2025.100552","DOIUrl":"10.1016/j.impact.2025.100552","url":null,"abstract":"<div><div>Although the ecotoxicity of polystyrene nanoplastics (PS-NP) to fish has been widely reported, their impact on the metabolic processes in fish gills and the underlying mechanisms remains unclear. Here, we investigated the effects of PS-NP on the morphology, oxidative stress, and metabolism of <em>Acrossocheilus yunnanensis</em> gills using conventional physicochemical indicators and metabolomics analysis. The results showed that PS-NP caused oxidative stress, and resulted in gill tissue lesions (e.g., proliferation and sloughing of gill epithelial cells). Metabolomics results showed that PS-NP exposure induced 75–164 differentially expressed metabolites (DEMs) in fish gills, and they were mainly related to lipid metabolism. DEMs induced by high concentration of PS-NP compared with low concentration of PS-NP were not only significantly enriched in glycerophospholipid metabolism, but also in sphingolipid metabolism, nucleic acid metabolism, and a variety of signaling pathways. In conclusion, the results of this work suggest that PS-NP cause disruption of phospholipid metabolism mainly by disrupting the integrity of gill tissue, which provides a new perspective for understanding the impact mechanism of PS-NP on fish gills. Given that fish play essential roles in maintaining ecological balance, the adverse effects of PS-NP on fish gills could ultimately disrupt the stability and health of the aquatic ecosystem.</div></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"37 ","pages":"Article 100552"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143480368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A catalytic perspective to nanomaterials reactivity-based toxicity; implications for single- and multiple-component nanomaterials (nanocomposites) 纳米材料反应毒性的催化研究对单组分和多组分纳米材料（纳米复合材料）的影响。

IF 4.7 3区环境科学与生态学

NanoImpact Pub Date : 2025-01-01 DOI: 10.1016/j.impact.2025.100542

Miguel A. Bañares, Victor Alcolea-Rodriguez , Raquel Portela

{"title":"A catalytic perspective to nanomaterials reactivity-based toxicity; implications for single- and multiple-component nanomaterials (nanocomposites)","authors":"Miguel A. Bañares, Victor Alcolea-Rodriguez , Raquel Portela","doi":"10.1016/j.impact.2025.100542","DOIUrl":"10.1016/j.impact.2025.100542","url":null,"abstract":"<div><div>The extended use of a given product normally precedes concerns about it. The reactivity-based nanotoxicity is a major concern that must be tackled from its fundamental understanding to its regulatory management. Moreover, concepts and ideas must seamlessly flow between relevant performers. Functional nanomaterials have been used in many fields; among these, catalysis is probably the earliest more extended application of nanomaterials, these are engineered to afford specific properties, and are typically known as Engineered Nanomaterials (ENMs). Heterogenous catalysis shares its basic features with reactivity-based toxicity. In both cases, we are dealing with phenomena triggered by reactions occurring at the surface of the nanomaterial. Therefore, the extensive knowledge in heterogeneous catalysis is key to understanding reactivity-based nanotoxicology. In this regard, determining surface exposure is fundamental to mechanistically comprehend dose-response, similar to how catalysis shifted from mass-based to surface-centered metrics. Catalysis science made a further refinement iteration: reactions occur at surfaces, though not all surfaces are necessarily reactive, making it crucial to normalize per reactive site. This perspective focuses on two key aspects that link heterogeneous catalysis and reactivity-based nanotoxicity: the reactive sites on the surface of nanomaterials and how different combinations of nanomaterials appear and perform. A comment is also made regarding the somewhat vague term <em>‘multicomponent nanomaterial</em>,’ which is contrasted with the well-defined, established, and widely accepted term <em>‘nanocomposite’</em> within the chemical community. Clear and precise terminology and concepts are essential for effective research and regulation.</div></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"37 ","pages":"Article 100542"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143008507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bayesian network modelling for predicting the environmental hazard of silver nanomaterials in soils

IF 4.7 3区环境科学与生态学

NanoImpact Pub Date : 2025-01-01 DOI: 10.1016/j.impact.2025.100553

Irini Furxhi , Sarah Roberts , Richard Cross , Elise Morel , Anna Costa , Elma Lahive

{"title":"Bayesian network modelling for predicting the environmental hazard of silver nanomaterials in soils","authors":"Irini Furxhi , Sarah Roberts , Richard Cross , Elise Morel , Anna Costa , Elma Lahive","doi":"10.1016/j.impact.2025.100553","DOIUrl":"10.1016/j.impact.2025.100553","url":null,"abstract":"<div><div>In alignment with the European Union's Green Deal, which directs safe and sustainable practices for all chemicals, including nanomaterials (NMs) and advanced materials (AdMa), this study addresses the environmental hazard of silver NMs to terrestrial ecosystems. In the context of safe and sustainable by design (SSbD) framework, there is a need for methodologies that integrate pHysicochemical characteristics and experimental conditions to reliably predict their hazards to exposed species. Bayesian Networks (BN) represent a pivotal machine-learning (ML) tool with the potential to accelerate the SSbD process by leveraging predictive capabilities. In this study, we employed BN models trained on a literature-derived dataset capturing the ecotoxicity of silver (Ag) NMs in soils, focusing on predicting chronic no-observed effect concentrations (chronic NOECs). The model incorporates physicochemical characteristics such as surface treatment, nominal particle diameter and particle shape as provided by manufacturers, species information such as life stage and taxonomic class, and exposure medium characteristics. The BN, refined through expert insights, achieved an average predictive accuracy of approximately 82 % across the output labels. The study also extracted interpretable rules from the BN, outlining environmental safety criteria and identified key factors influencing NM hazard for terrestrial organisms. The critical need for experimental datasets that provide fuller details of physiochemical characteristics and experimental conditions, as well as current limitations, are highlighted. This modelling approach facilitates the rapid screening of the potential hazards of AgNMs to terrestrial ecosystems, with the potential to accelerate safety evaluations and rationalise experimental demands.</div></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"37 ","pages":"Article 100553"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanoparticles induced glomerular endothelial leakiness promoting albuminuria level

IF 4.7 3区环境科学与生态学

NanoImpact Pub Date : 2025-01-01 DOI: 10.1016/j.impact.2025.100548

Yingqi Wang , Shen Zhao , Nengyi Ni , Hongyu Chen , Wenjian Zhao , Kuoran Xing , Xiao Sun , Xiuli Jing

{"title":"Nanoparticles induced glomerular endothelial leakiness promoting albuminuria level","authors":"Yingqi Wang , Shen Zhao , Nengyi Ni , Hongyu Chen , Wenjian Zhao , Kuoran Xing , Xiao Sun , Xiuli Jing","doi":"10.1016/j.impact.2025.100548","DOIUrl":"10.1016/j.impact.2025.100548","url":null,"abstract":"<div><div>Nanomaterials have been widely used in various fields due to their excellent properties. However, the long-term exposure of humans to the environment of nanomaterials may lead to some pathological and physiological changes, such as the disruption of the glomerular filtration barrier (GFB), which can lead to high permeability and filterable albumin. Glomerular albuminuria results from the failure of the GFB, which may be caused by activation of the Notch1 signaling pathway. The reduction of glomerular endocalyx results in the level of VE-cadherin being diminished between endothelial cells, leading to leakiness in the endothelium. As previously discovered, certain nanoparticles, such as negatively charged gold nanoparticles of appropriate size, can directly facilitate the onset of endothelial leakiness through disrupting connections between vascular endothelial cells, in a process known as nanomaterial-induced endothelial leakiness (NanoEL). In this study, the negatively charged Au NPs with a diameter of 20 nm were synthesized first. Through the co-incubation of 20 nm Au NPs with a single layer of continuous HUVECs, we revealed that the synthesized 20 nm Au NPs could break the tight junctions and cause endothelial cell leakage. In addition, by constructing an endothelial leakage model between glomerular vascular endothelial cells, we confirmed that 20 nm Au NPs can generate NanoEL between glomerular endothelial cells, involving downstream processes coinciding with Notch signaling activation, resulting in the increase of urinary protein. The results of this study add to the understanding of the behaviour of nanoparticles in complex biological systems.</div></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"37 ","pages":"Article 100548"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143427650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regulatory preparedness for multicomponent nanomaterials: Current state, gaps and challenges of REACH 多组分纳米材料的监管准备：REACH的现状、差距和挑战。

IF 4.7 3区环境科学与生态学

NanoImpact Pub Date : 2025-01-01 DOI: 10.1016/j.impact.2024.100538

Neil Hunt , Vikram Kestens , Kirsten Rasmussen , Elena Badetti , Lya G. Soeteman-Hernández , Agnes G. Oomen , Willie Peijnenburg , Danail Hristozov , Hubert Rauscher

{"title":"Regulatory preparedness for multicomponent nanomaterials: Current state, gaps and challenges of REACH","authors":"Neil Hunt , Vikram Kestens , Kirsten Rasmussen , Elena Badetti , Lya G. Soeteman-Hernández , Agnes G. Oomen , Willie Peijnenburg , Danail Hristozov , Hubert Rauscher","doi":"10.1016/j.impact.2024.100538","DOIUrl":"10.1016/j.impact.2024.100538","url":null,"abstract":"<div><div>In 2018 the European Commission adopted revisions to the Annexes of Regulation (EC) No 1907/2006 concerning registration, evaluation, authorisation and restriction of chemicals (REACH) to introduce nanomaterial-specific clarifications and provisions. Multicomponent nanomaterial (MCNM) is a non-regulatory term that has been used in recent EU-funded projects to describe nanomaterials with a complex structure and/or composition and which are expected to be increasingly used in products in the near future. This paper examines the regulatory preparedness of REACH, and its revised Annexes, for MCNMs. Several situations have been identified where there is potential confusion and uncertainty around how regulatory definitions used in REACH should be applied to MCNMs. If a MCNM cannot be identified as falling within a specific definition, understanding the regulatory obligations that apply to it is very difficult. Examples of these grey areas include how the term “surface functionalisation or modification” applies when a chemical is physisorbed to the surface of a nanoform, and the identity of the substance that should be registered when the modification takes it outside the definition of a nanoform. We conclude that the regulatory preparedness can be improved by amending the REACH guidance on information requirements for nanoforms and revising the definition of “nanoform” in line with the updated EC Recommendation on the definition of nanomaterial.</div></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"37 ","pages":"Article 100538"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Micro-nanoscale polystyrene co-exposure impacts the uptake and translocation of arsenic and boscalid by lettuce (Lactuca sativa) 微纳米聚苯乙烯共暴露影响生菜对砷和硼酸钠的吸收和转运。

IF 4.7 3区环境科学与生态学

NanoImpact Pub Date : 2025-01-01 DOI: 10.1016/j.impact.2025.100541

Trung Huu Bui , Nubia Zuverza-Mena , Emilie Kendrick , Carlos Tamez , Manavi Yadav , Sarah Alotaibi , Christian Dimkpa , Glen DeLoid , Omowunmi Sadik , Philip Demokritou , Jason C. White

{"title":"Micro-nanoscale polystyrene co-exposure impacts the uptake and translocation of arsenic and boscalid by lettuce (Lactuca sativa)","authors":"Trung Huu Bui , Nubia Zuverza-Mena , Emilie Kendrick , Carlos Tamez , Manavi Yadav , Sarah Alotaibi , Christian Dimkpa , Glen DeLoid , Omowunmi Sadik , Philip Demokritou , Jason C. White","doi":"10.1016/j.impact.2025.100541","DOIUrl":"10.1016/j.impact.2025.100541","url":null,"abstract":"<div><div>The influence of micro-nanoplastics (MNPs) on the fate and effects of other pollutants present in the environment is largely unknown. This study evaluated if the root exposure to MNPs (polystyrene, PS; 20 or 1000 nm) had an impact on the accumulation of arsenic and boscalid (As and Bos) in lettuce (<em>Lactuca sativa</em>). Under hydroponic conditions, plants were co-exposed to MNPs at 10 or 50 mg/L, and to 1 mg/L of each environmental pollutant (EP). For soil-like media, plants were exposed to MNPs at 50 and EPs at 10 mg/kg. Phytotoxicity was enhanced by PS under both growth conditions, particularly by nanoscale PS (nPS), although impacts were less in potting mix-grown plants. Nanoscale PS had a greater impact than microscale PS (μPS) on As fate; the As translocation factor from roots to the edible shoots was increased 3-fold in plants exposed to nPS (50 mg/L) and EPs. PS dose and size had a variable impact on Bos uptake and translocation. Fluorescent microscopy analysis of lettuce co-exposed to MNPs and EPs suggests that nPS is entering the roots and translocating to the leaves, while μPS mostly remains in the roots. Pyrolysis-GC/MS showed that in solid media, the presence of EPs significantly increased the translocation of nPS to lettuce shoots from 4.43 ± 0.53 to 46.6 ± 9.7 mg/kg, while the concentration of μPS in the shoots remained the same regardless of the presence of EPs (ranging between 13.2 ± 5.5 to 14.2 ± 4.1 mg/kg). These findings demonstrate that co-exposure of MNPs with other EPs can significantly impact co-contaminant accumulation and toxicity, presenting an unknown risk to humans and other receptors.</div></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"37 ","pages":"Article 100541"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142965662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of polystyrene nanoplastics on physiology, nutrient uptake, and root system architecture of aeroponically grown citrus plants 聚苯乙烯纳米塑料对气培柑橘植株生理、养分吸收和根系结构的影响。

IF 4.7 3区环境科学与生态学

NanoImpact Pub Date : 2025-01-01 DOI: 10.1016/j.impact.2024.100536

Khalid Hussain , John-Paul Fox , Xingmao Ma , Lorenzo Rossi

{"title":"Impact of polystyrene nanoplastics on physiology, nutrient uptake, and root system architecture of aeroponically grown citrus plants","authors":"Khalid Hussain , John-Paul Fox , Xingmao Ma , Lorenzo Rossi","doi":"10.1016/j.impact.2024.100536","DOIUrl":"10.1016/j.impact.2024.100536","url":null,"abstract":"<div><div>The widespread presence of plastic pollution has become a challenge for both aquatic and terrestrial plants. Notably, nanoplastics (NPs) have been found to enter the root tissues and translocate to different organs of plants; however, most previous studies were performed using crop or vegetable seedlings, and the extent NPs accumulation in fruit tree plants, particularly citrus, and their impacts remains unclear. This study was designed to fill this gap by determining the uptake and accumulation of green, fluorescent polystyrene nanoplastics (PS-NPs) of two different sizes (20 nm and 50 nm in diameter) in citrus rootstock (‘US-942’) in an aeroponic system and their impact on plant growth and physiological functions, nutrient uptake, and root system architectural and anatomical traits. The 20 nm PS-NPs negatively impacted the root system architecture (total root length, root surface area, number of root forks) and nutrient contents (N, P, K, Mg, S, B, Fe, Cu, Mn) at both 15 and 30 days after treatment; however, no significant differences were recorded for growth and physiological parameters. Microscopic analysis of roots revealed that under both the PS-NPs treatments, root apoplastic barriers were fully developed near the root tips. Furthermore, PS-NPs are predominantly adhered to the root surface, and no signs of uptake and translocation were recorded in root sections. However, alterations to the external root cell layers were observed. This research sheds light on the impact of PS-NPs on plant roots and their physiology and contributes to a better understanding of these emerging pollutants on tree crop horticulture.</div></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"37 ","pages":"Article 100536"},"PeriodicalIF":4.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142770167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gut-lung microbiota dynamics in mice exposed to Nanoplastics 暴露于纳米塑料的小鼠肠肺微生物群动态。

IF 4.7 3区环境科学与生态学

NanoImpact Pub Date : 2024-10-01 DOI: 10.1016/j.impact.2024.100531

Nur Kaluç , Sara Bertorello , Oğuz Kaan Tombul , Simone Baldi , Giulia Nannini , Gianluca Bartolucci , Elena Niccolai , Amedeo Amedei

{"title":"Gut-lung microbiota dynamics in mice exposed to Nanoplastics","authors":"Nur Kaluç , Sara Bertorello , Oğuz Kaan Tombul , Simone Baldi , Giulia Nannini , Gianluca Bartolucci , Elena Niccolai , Amedeo Amedei","doi":"10.1016/j.impact.2024.100531","DOIUrl":"10.1016/j.impact.2024.100531","url":null,"abstract":"<div><div>Concern has grown over potential health effects of micro- and nanoplastics (M/NPs) exposure. There is significant interest in understanding their impact on animal and human microbiota due to its crucial role in preserving health, as research in this area is rapidly advancing. We conducted a sub-chronic exposure study involving 12 male mice, divided into two groups: a control group (<em>n</em> = 6) and a PET-NPs exposure group (n = 6). PET-NPs, administered by oral gavage at a dose of 0.5 mg/day in 0.1 ml/mice, were given daily for 28 days. Microbiota analyses were performed on lung, colon, oral cavity, and stool samples using 16S rRNA sequencing. Additionally, fecal short and medium-chain fatty acids were analyzed by GC/MS. No significant changes were observed in the fecal and oral microbiome of the treated mice, nor in the fecal fatty acid levels. However, there were prominent alterations in the colon, characterized by increased abundance of Gram-negative bacteria belonging to <em>Veillonella</em> and <em>Prevotella</em> genera, and of amino acid metabolism pathways, coupled with a decrease in <em>Lactobacillus</em>. PET-NPs ingestion caused unexpected alterations in the lung microbiome with an increase in the <em>Pseudomonas</em> and changes in microbial energy metabolism and nitrogen utilization. This study provides insights into the differential impact of PET-NPs exposure on various microbiome niches.</div></div>","PeriodicalId":18786,"journal":{"name":"NanoImpact","volume":"36 ","pages":"Article 100531"},"PeriodicalIF":4.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142504274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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