Medical Gas Research最新文献_第7页

Quantitative risk assessment of respiratory exposure to acrylonitrile vapor in petrochemical industry by U.S. Environmental Protection Agency method: a cross-sectional study. 美国环境保护署方法对石化工业中丙烯腈蒸气呼吸暴露的定量风险评估:一项横断面研究。

IF 2.9

Medical Gas Research Pub Date : 2023-07-01 DOI: 10.4103/2045-9912.350859

Ali Asghar Sajedian, Ali Karimi, Mohsen Sadeghi Yarandi, Vahid Ahmadi Moshiran, Aysa Ghasemi Koozekonan, Farideh Golbabaei

{"title":"Quantitative risk assessment of respiratory exposure to acrylonitrile vapor in petrochemical industry by U.S. Environmental Protection Agency method: a cross-sectional study.","authors":"Ali Asghar Sajedian, Ali Karimi, Mohsen Sadeghi Yarandi, Vahid Ahmadi Moshiran, Aysa Ghasemi Koozekonan, Farideh Golbabaei","doi":"10.4103/2045-9912.350859","DOIUrl":"https://doi.org/10.4103/2045-9912.350859","url":null,"abstract":"Acrylonitrile is a potential carcinogen for humans, and exposure to this substance can cause adverse effects for workers. This study aimed to carcinogenic and health risk assessment of acrylonitrile vapor exposure in exposed personnel of a petrochemical complex. This crosssectional study was performed in 2019 in a petrochemical complex. In this study, to sample and determine acrylonitrile's respiratory exposure, the method provided by the National Institute of Occupational Safety and Health (NIOSH 1601) was used, and a total of 45 inhaled air samples were sampled from men workers, aged 39.43 ± 9.37 years. All subjects' mean exposure to acrylonitrile vapors was 71.1 ± 122.8 μg/m3. Also, the mean exposure index among all subjects was 0.02 ± 0.034. The non-carcinogenic risk assessment results showed that the mean Hazard quotient index was 4.04 ± 6.93. The mean lifetime cancer risk index was also 2.1 × 10-3 ± 3.5 × 10-3 and was in the definite risk range. Considering that both carcinogenicity and health indicators of exposure to acrylonitrile in the studied petrochemical complex are more than the recommended limits, the necessary engineering and management measures to control and manage the risk to an acceptable level are essential to improving the worker's health.","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"13 3","pages":"142-148"},"PeriodicalIF":2.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d3/65/MGR-13-142.PMC9979210.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10825631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nitric oxide therapy is beneficial to rehabilitation in professional soccer players: clinical and experimental studies. 一氧化氮治疗对职业足球运动员康复有益:临床和实验研究。

IF 2.9

Medical Gas Research Pub Date : 2023-07-01 DOI: 10.4103/2045-9912.344983

Victoria A Zaborova, Alexandra V Butenko, Anatoly B Shekhter, Alexey L Fayzullin, Alexander V Pekshev, Natalia B Serejnikova, Ol'ga V Chigirintseva, Kira Yu Kryuchkova, Konstantin G Gurevich

{"title":"Nitric oxide therapy is beneficial to rehabilitation in professional soccer players: clinical and experimental studies.","authors":"Victoria A Zaborova, Alexandra V Butenko, Anatoly B Shekhter, Alexey L Fayzullin, Alexander V Pekshev, Natalia B Serejnikova, Ol'ga V Chigirintseva, Kira Yu Kryuchkova, Konstantin G Gurevich","doi":"10.4103/2045-9912.344983","DOIUrl":"https://doi.org/10.4103/2045-9912.344983","url":null,"abstract":"Nitric oxide can activate neutrophils and macrophages, facilitate the synthesis of collagen, which allows significantly accelerating the regeneration of traumatized tissues. We studied the effects of nitric oxide-containing gas flow generated by plasma-chemical device \"Plason\" in a rat model of full-thickness wounds. Histological and morphometric analyses revealed that Plason treated wounds expressed significantly fewer signs of inflammation and contained a more mature granulation tissue on day 4 after the operation. Considering the results of the experimental study, we applied the Plason device in sports medicine for the treatment of lower limb bruises of 34 professional soccer players. Athletes were asked to assess the intensity of pain with the Visual Analogue Scale. Girths of their lower limbs were measured over the course of rehabilitation. Nitric oxide therapy of full-thickness wounds inhibited inflammation and accelerated the regeneration of skin and muscle tissues. Compared with the control, we observed a significant reduction in pain syndrome on days 2-7 after injuries, edema, and hematoma, and shortened treatment duration. This pilot study indicates that the use of nitric oxide is a promising treatment method for sports injuries.","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"13 3","pages":"128-132"},"PeriodicalIF":2.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/49/3a/MGR-13-128.PMC9979209.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10825632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Hydrogen exerts neuroprotective effects by inhibiting oxidative stress in experimental diabetic peripheral neuropathy rats. 氢通过抑制实验性糖尿病周围神经病变大鼠氧化应激发挥神经保护作用。

IF 2.9

Medical Gas Research Pub Date : 2023-04-01 DOI: 10.4103/2045-9912.345171

Xiao-Chen Han, Zhou-Heng Ye, Hui-Jun Hu, Qiang Sun, Dan-Feng Fan

{"title":"Hydrogen exerts neuroprotective effects by inhibiting oxidative stress in experimental diabetic peripheral neuropathy rats.","authors":"Xiao-Chen Han, Zhou-Heng Ye, Hui-Jun Hu, Qiang Sun, Dan-Feng Fan","doi":"10.4103/2045-9912.345171","DOIUrl":"https://doi.org/10.4103/2045-9912.345171","url":null,"abstract":"Diabetic peripheral neuropathy (DPN) is a complex disorder caused by long-standing diabetes. Oxidative stress was considered the critical creed in this DPN pathophysiology. Hydrogen has antioxidative effects on diabetes mellitus and related complications. However, there is still no concern on the beneficial effects of hydrogen in DPN. This paper aimed to evaluate the effects of exogenous hydrogen to reduce the severity of DPN in streptozotocin-induced diabetic rats. Compared with hydrogen-rich saline treatment, hydrogen inhalation significantly reduced blood glucose levels in diabetic rats in the 4th and 8th weeks. With regard to nerve function, hydrogen administration significantly attenuated the decrease in the velocity of motor nerve conduction in diabetic animals. In addition, hydrogen significantly attenuated oxidative stress by reducing the level of malondialdehyde, reactive oxygen species, and 8-hydroxy-2-deoxyguanosine and meaningfully enhanced the antioxidant capability by partially restoring the activities of superoxide dismutase. Further studies showed that hydrogen significantly upregulated the expression of nuclear factor erythroid-2-related factor 2 and downstream proteins such as catalase and hemeoxygenase-1 in the nerves of diabetic animals. Our paper showed that hydrogen exerts significant protective effects in DPN by downregulating oxidative stress via the pathway of nuclear factor erythroid-2-related factor 2, which suggests its potential value in clinical applications.","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"13 2","pages":"72-77"},"PeriodicalIF":2.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8b/a7/MGR-13-72.PMC9555025.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10783731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

New scientific definitions: hyperbaric therapy and hyperbaric oxygen therapy. 新的科学定义:高压氧治疗和高压氧治疗。

IF 2.9

Medical Gas Research Pub Date : 2023-04-01 DOI: 10.4103/2045-9912.356475

Paul G Harch

引用次数: 2

Realizing brain therapy with “smart medicine”: Mechanism and case report of molecular hydrogen inhalation for Parkinson's disease 用“智慧医学”实现脑治疗:分子氢吸入治疗帕金森病的机理及病例报告

Medical Gas Research Pub Date : 2023-01-01 DOI: 10.4103/2045-9912.385949

Yusuke Ichikawa, Bunpei Sato, Shin-ichi Hirano, Yoshiyasu Takefuji, Fumitake Satoh

引用次数: 0

Use of vedolizumab combined with hyperbaric oxygen therapy to treat enteric fistula in Crohn's disease 使用vedolizumab联合高压氧治疗克罗恩病肠瘘

Medical Gas Research Pub Date : 2023-01-01 DOI: 10.4103/2045-9912.385948

EnioChaves Oliveira, Mauro Bafutto, AlexandreAugusto Ferreira Bafutto, CarlosAlberto Ximenes Filho

引用次数: 0

Hyperbaric oxygen therapy increases the effect of 5-fluorouracil chemotherapy on experimental colorectal cancer in mice 高压氧治疗增加5-氟尿嘧啶化疗对小鼠实验性结直肠癌的作用

Medical Gas Research Pub Date : 2023-01-01 DOI: 10.4103/2045-9912.385944

VanessaForesto Machado, JoséJoaquim Ribeiro da Rocha, RogérioSerafim Parra, MarleyRibeiro Feitosa, CaioAbner Leite, StefâniaBovo Minto, SérgioBritto Garcia, ThiagoMattar Cunha, Omar Feres

引用次数: 0

The role of nitric oxide and hydrogen sulfide in spinal cord injury: an updated review 一氧化氮和硫化氢在脊髓损伤中的作用:最新综述

Medical Gas Research Pub Date : 2023-01-01 DOI: 10.4103/2045-9912.385946

Haitao Shen, Gang Cui, Xiaoliang Wen, Yang Ye, Zhengquan Yu, Gang Chen

引用次数: 0

Neuroprotective effects of hydrogen sulfide in Parkinson's disease 硫化氢对帕金森病的神经保护作用

Medical Gas Research Pub Date : 2023-01-01 DOI: 10.4103/2045-9912.385945

Haitao Shen, Zhengquan Yu, Yang Ye, Jinhui Xu, Gang Chen

引用次数: 0

Effects of dexmedetomidine, fentanyl and magnesium sulfate added to ropivacaine on sensory and motor blocks in lower abdominal surgery: a randomized clinical trial 右美托咪定、芬太尼和硫酸镁加入罗哌卡因对下腹部手术感觉和运动阻滞的影响:一项随机临床试验

Medical Gas Research Pub Date : 2023-01-01 DOI: 10.4103/2045-9912.385947

Alireza Kamali, Hesameddin Modir, Negar Hafez-Alsehe, Amir Almasi-Hashiani

引用次数: 0