Medical Gas ResearchPub Date : 2025-03-01Epub Date: 2024-06-26DOI: 10.4103/mgr.MEDGASRES-D-24-00022
Yefan Duan, Jianfei Sun
{"title":"New approach of modern pharmacology: from gasotransmitters to traditional mineral drugs.","authors":"Yefan Duan, Jianfei Sun","doi":"10.4103/mgr.MEDGASRES-D-24-00022","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00022","url":null,"abstract":"","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"139-141"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical Gas ResearchPub Date : 2025-03-01Epub Date: 2024-10-02DOI: 10.4103/mgr.MEDGASRES-D-24-00058
Anatoly N Osipov, Natalya A Urakova, Aleksandr L Urakov, Petr D Shabanov
{"title":"Warm alkaline hydrogen peroxide solution as an oxygen-releasing antihypoxic drug: potential benefits and applications.","authors":"Anatoly N Osipov, Natalya A Urakova, Aleksandr L Urakov, Petr D Shabanov","doi":"10.4103/mgr.MEDGASRES-D-24-00058","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00058","url":null,"abstract":"","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"134-135"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative study on the anti-inflammatory and protective effects of different oxygen therapy regimens on lipopolysaccharide-induced acute lung injury in mice.","authors":"Xinhe Wu, Yanan Shao, Yongmei Chen, Wei Zhang, Shirong Dai, Yajun Wu, Xiaoge Jiang, Xinjian Song, Hao Shen","doi":"10.4103/mgr.MEDGASRES-D-24-00044","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00044","url":null,"abstract":"<p><p>Oxygen therapy after acute lung injury can regulate the inflammatory response and reduce lung tissue injury. However, the optimal exposure pressure, duration, and frequency of oxygen therapy for acute lung injury remain unclear. In the present study, after intraperitoneal injection of lipopolysaccharide in ICR mice, 1.0 atmosphere absolute (ATA) pure oxygen and 2.0 ATA hyperbaric oxygen treatment for 1 hour decreased the levels of proinflammatory factors (interleukin-1beta and interleukin-6) in peripheral blood and lung tissues. However, only 2.0 ATA hyperbaric oxygen increased the mRNA levels of anti-inflammatory factors (interleukin-10 and arginase-1) in lung tissue; 3.0 ATA hyperbaric oxygen treatment had no significant effect. We also observed that at 2.0 ATA, the anti-inflammatory effect of a single exposure to hyperbaric oxygen for 3 hours was greater than that of a single exposure to hyperbaric oxygen for 1 hour. The protective effect of two exposures for 1.5 hours was similar to that of a single exposure for 3 hours. These results suggest that hyperbaric oxygen alleviates lipopolysaccharide-induced acute lung injury by regulating the expression of inflammatory factors in an acute lung injury model and that appropriately increasing the duration and frequency of hyperbaric oxygen exposure has a better tissue-protective effect on lipopolysaccharide-induced acute lung injury. These results could guide the development of more effective oxygen therapy regimens for acute lung injury patients.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":" ","pages":"171-179"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical Gas ResearchPub Date : 2025-03-01Epub Date: 2024-06-26DOI: 10.4103/mgr.MEDGASRES-D-24-00002
Steven McGuigan, Brendan F Abrahams, David A Scott
{"title":"A narrative review of gas separation and conservation technologies during xenon anesthesia.","authors":"Steven McGuigan, Brendan F Abrahams, David A Scott","doi":"10.4103/mgr.MEDGASRES-D-24-00002","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00002","url":null,"abstract":"<p><p>Xenon gas has significant advantages over conventional general anesthetic agents but its use has been limited by the cost associated with its production. Xenon also has significant potential for medical use in the treatment of acquired brain injuries and for mental health disorders. As the demand for xenon gas from other industries increases, the costs associated with its medical use are only likely to increase. One solution to mitigate the significant cost of xenon use in research or medical care is the conservation of xenon gas. During delivery of xenon anesthesia, this can be achieved either by separating xenon from the other gases within the anesthetic circuit, conserving xenon and allowing other gases to be excluded from the circuit, or by selectively recapturing xenon utilized during the anesthetic episode at the conclusion of the case. Several technologies, including the pressurization and cooling of gas mixtures, the utilization of gas selective membranes and the utilization of gas selective adsorbents have been described in the literature for this purpose. These techniques are described in this narrative review along with important clinical context that informs how these technologies might be best applied. Whilst these technologies are discussed in the context of xenon general anesthesia, they could be applied in the delivery of xenon gas inhalation for other therapeutic purposes.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"93-100"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical Gas ResearchPub Date : 2025-03-01Epub Date: 2024-08-02DOI: 10.4103/mgr.MEDGASRES-D-24-00016
Zixin Wang, Yin Wang
{"title":"Hydrogen sulfide: a rising star for cancer treatment.","authors":"Zixin Wang, Yin Wang","doi":"10.4103/mgr.MEDGASRES-D-24-00016","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00016","url":null,"abstract":"","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"114-116"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical Gas ResearchPub Date : 2025-03-01Epub Date: 2024-09-25DOI: 10.4103/mgr.MEDGASRES-D-24-00012
Md Habibur Rahman, Cheol-Su Kim, Kyu-Jae Lee
{"title":"Molecular hydrogen gas and its therapeutic potential in recent disease progression.","authors":"Md Habibur Rahman, Cheol-Su Kim, Kyu-Jae Lee","doi":"10.4103/mgr.MEDGASRES-D-24-00012","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00012","url":null,"abstract":"","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"120-121"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical Gas ResearchPub Date : 2025-03-01Epub Date: 2024-10-02DOI: 10.4103/mgr.MEDGASRES-D-24-00059
Kenneth Maiese
{"title":"Biological gases, oxidative stress, artificial intelligence, and machine learning for neurodegeneration and metabolic disorders.","authors":"Kenneth Maiese","doi":"10.4103/mgr.MEDGASRES-D-24-00059","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00059","url":null,"abstract":"","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"145-147"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fatigue disappearance in hemodialysis patients by dual approach with hydrogen gas inhalation and hydrogen-enriched dialysate: two case reports.","authors":"Ryoichi Nakazawa, Shintaro Nagami, Hiroshi Nozaki, Minako Yataka, Kazuhiro Akiyama, Takashi Uchino, Nakanobu Azuma","doi":"10.4103/mgr.MEDGASRES-D-24-00024","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00024","url":null,"abstract":"","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"122-123"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515080/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lung function and blood gas of rats after different protocols of hypobaric exposure.","authors":"Lijun Yin, Yukun Wen, Zhixin Liang, Zhenbiao Guan, Xuhua Yu, Jiajun Xu, Shifeng Wang, Wenwu Liu","doi":"10.4103/mgr.MEDGASRES-D-24-00039","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00039","url":null,"abstract":"<p><p>High-altitude pulmonary edema (HAPE) is a common disease observed in climbers, skiers and soldiers who ascend to high altitudes without previous acclimatization. Thus, a reliable and reproducible animal model that can mimic the mechanisms of pathophysiologic response in humans is crucial for successful investigations. Our results showed that exposure to 4500 m for 2 days had little influence on lung function or blood gas, and exposure to 6000 m for 2 or 3 days could change lung function and blood gas, but most parameters returned to nearly normal levels within 48 hours. This study indicates that exposure to 6000 m for 3 days may induce evident lung edema and significantly alter lung function and blood gas, which may mimic HAPE in clinical practice. Thus, this animal model of HAPE may be used in future studies on HAPE.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"180-187"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}