Medicine最新文献

{"title":"The application and effect evaluation of continuity precision nursing in patients undergoing coronary angiography and stent implantation: A study of clinical outcomes.","authors":"Limin Tan, Xiaojing Tan, Cangyun Zhang, Lei Tao, Yuan Liao","doi":"10.1097/MD.0000000000041879","DOIUrl":"10.1097/MD.0000000000041879","url":null,"abstract":"<p><p>Coronary artery disease is a major global health burden, with percutaneous coronary intervention (PCI) serving as a key treatment strategy. Despite its efficacy, challenges such as in-stent restenosis, medication nonadherence, unhealthy lifestyles, and psychological distress hinder optimal recovery. Continuity-based precision nursing, which integrates personalized care and multidisciplinary support, offers a potential solution. Therefore, the purpose of this study is to evaluate the effectiveness of continuity-based precision nursing compared to conventional nursing in improving postoperative outcomes for PCI patients. This includes assessing its impact on cardiac function recovery, complication prevention, medication adherence, lifestyle modifications, psychological well-being, and overall quality of life. This study included 112 PCI patients treated from January 2023 to January 2024, divided into an experimental group (continuity-based precision nursing) and a control group (conventional nursing). Propensity score matching resulted in 45 matched pairs. Data collected included demographics, postoperative cardiac function, medication adherence, lifestyle changes, psychological status, complications, satisfaction, and health-related quality of life. Statistical analyses were performed using SPSS, with P < .05 considered significant. Continuity-based precision nursing showed significant benefits over conventional nursing. At 1 month post-PCI, the experimental group had higher left ventricular ejection fraction ≥ 50% rates (86.7% vs 75.6%) and lower in-stent restenosis (6.7% vs 17.8%) and residual stenosis rates (8.9% vs 24.4%, P = .048). Medication adherence was improved (86.7% vs 66.7%, P = .02), with higher rates eof smoking cessation (77.8% vs 55.6%, P = .01), healthy eating (84.4% vs 66.7%, P = .03), and regular exercise (80.0% vs 62.2%, P = .02). Anxiety and depression scores were significantly lower in the experimental group post-intervention. Patient satisfaction (92.5 ± 4.2 vs 85.7 ± 6.1, P < .01) and health-related quality of life (88.4 ± 5.0 vs 81.2 ± 6.0, P < .01) were also markedly higher. Continuity-based precision nursing significantly enhances postoperative outcomes in PCI patients, improving cardiac function, adherence, lifestyle behaviors, and psychological well-being. This model provides a comprehensive framework for coronary artery disease care, with potential for broader clinical application. Further research should evaluate its long-term impact and scalability in diverse settings.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 12","pages":"e41879"},"PeriodicalIF":1.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936598/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abdominal bleeding secondary to isolated mesenteric injury following blunt abdominal trauma: A case report.","authors":"Zhiqiang Ming, Chao Xiao, Rui Xiao, Yongtao Zhang, Xiaoli Hu","doi":"10.1097/MD.0000000000041920","DOIUrl":"10.1097/MD.0000000000041920","url":null,"abstract":"<p><strong>Rationale: </strong>Isolated mesenteric injury often results from traffic accidents causing blunt abdominal trauma, exhibit nonspecific symptoms and signs. Most mesenteric injuries occur concurrently with injuries to other organs, such as the liver and spleen. As a result, the incidence of isolated mesenteric injury is very low and often misdiagnosed.</p><p><strong>Patient concerns: </strong>A 49-year-old male patient presented with abdominal pain following a traffic accident more than 5 hours before admission. Upon admission, his blood pressure was normal but dropped sharply in a short time and presented with shock. Anemia, abrasions in the upper abdomen, cold skin on the dorsum of the foot, rebound pain, muscle tension, and noncoagulation of abdominal blood were all observed during the physical examination. Emergency plain and contrast-enhanced abdominal computed tomography (CT), and mesenteric artery CT angiography revealed a large volume of blood accumulated in the abdomen, pelvis, and jejunal mesentery. The jejunal wall and mesentery were edematous, with mesenteric distortion, and some branches of the inner jejunal artery were not clearly visualized. We found no evidence of liver or splenic rupture.</p><p><strong>Diagnoses: </strong>Mesenteric injury of the jejunum caused acute hemorrhagic anemia and hemorrhagic shock.</p><p><strong>Interventions: </strong>An emergency laparotomy was performed.</p><p><strong>Outcomes: </strong>An emergency laparotomy showed 3 hematomas close to the perforation site, 2 fully split tears in the jejunal mesentery, bleeding from partially exposed veins, a significant amount of blood and clots in the abdominal cavity, and serosal damage at the jejunal mesentery's root. The patient recovered well after we performed abdominal cavity drainage and jejunal mesenteric hemostasis and repair.</p><p><strong>Lessons: </strong>Isolated mesenteric injuries are very rare in clinical practice, and their clinical symptoms and signs are nonspecific, which makes them prone to misdiagnosis and oversight. When a patient satisfies the 4 requirements listed below: abdominal hemorrhage or hematoma; a history of abdominal trauma; no damage to high-risk organs like the liver or spleen; the CT-detected signs of mesenteric injury. Abdominal paracentesis or laparoscopy should be conducted to confirm the diagnosis and initiate further treatment.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 12","pages":"e41920"},"PeriodicalIF":1.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On the rising potential of interdisciplinary rehabilitation in neurological disorders: A mini-review.","authors":"Abdulhameed Tomeh, Abdul Hanif Khan Yusof Khan, Zalina Abu Zaid, King-Hwa Ling, Liyana Najwa Inche Mat, Hamidon Basri, Ahmad Luqman Md Pauzi, Muhammad Hibatullah Romli, Wan Aliaa Wan Sulaiman","doi":"10.1097/MD.0000000000041947","DOIUrl":"10.1097/MD.0000000000041947","url":null,"abstract":"<p><p>Collaboration among health and non-health professionals is growing exponentially as we approach the personalized medicine era, where the intervention plan is tailored according to the patient's needs. This collaboration aims to develop highly efficient, patient-centered, holistic approaches, rather than singular interventions. Interdisciplinary rehabilitation is a rising theme to coordinate the efforts of various professionals, with the ultimate goal of increasing rehabilitants' satisfaction and improving their overall quality of life. A typical rehabilitation team may comprise a rehabilitation physician, rehabilitation nurse, occupational therapist, physiotherapist, speech and language therapist, clinical psychologist, social worker, prosthetist, orthotist, rehabilitation engineer, and dietician. The need for inclusion of additional professions in the rehabilitation team is dynamic and varies depending on the population and health condition. Recently, various countries have begun incorporating interdisciplinary rehabilitation models into their healthcare frameworks. For example, the U.S. Veterans Affairs Polytrauma Rehabilitation Centers have set a precedent for integrating interdisciplinary approaches into neurological rehabilitation, while European nations such as Germany and Sweden have successfully implemented stroke and pain rehabilitation programs. Although interdisciplinary rehabilitation has demonstrated effectiveness in improving patient outcomes, further research is required to explore its long-term benefits, cost-effectiveness, and adaptability in resource-limited settings. In this mini-review, we summarize the current evidence on employing interdisciplinary rehabilitation in patients with neurological disorders and highlight the implications for future research and clinical practice.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 12","pages":"e41947"},"PeriodicalIF":1.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causal association between genetically predicted primary aldosteronism and aortic aneurysm and aortic dissection: A Mendelian randomization study.","authors":"Sen Liu, Jindong Wan, Yi Yang, Dan Wang, Jixin Hou, Peijian Wang","doi":"10.1097/MD.0000000000041951","DOIUrl":"10.1097/MD.0000000000041951","url":null,"abstract":"<p><p>Emerging research indicates a potential pathogenic overlap between primary aldosteronism (PA) and aortic aneurysm (AA)/aortic dissection (AD). Despite case reports suggest a potential link between PA and AA/AD, the causality of this relationship remains unclear. This study is the first to elucidate the causal association between genetically predicted PA and the risk of AA and AD through Mendelian randomization (MR) analysis. Genome-wide significant single nucleotide polymorphisms associated with PA were identified from publicly available genome-wide association study summary statistics. Genetic associations with AA and AD were obtained from the FinnGen database. The inverse-variance weighted (IVW) method, along with complementary MR analysis methods, was employed to generate primary estimates. Sensitivity analyses were performed to ensure the robustness of findings. MR analyses utilizing the IVW method revealed a significant causal association between genetically predicted PA and the risk of AA (OR = 1.038; 95% CI = 1.024-1.053; P < .01), thoracic AA (OR = 1.066; 95% CI = 1.045-1.087; P < .01) and AD (OR = 1.165; 95% CI = 1.113-1.219; P < .01). Conversely, no significant association was observed between PA and abdominal AA (OR = 1.013; 95% CI = 0.993-1.034; P = .210). There was no heterogeneity and horizontal pleiotropy in the MR analyses (P > .05). PA is genetically and causally associated with higher risks of AA and AD. More attention should be paid to the screening and treatment of PA to reduce the incidence of aortic diseases.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 12","pages":"e41951"},"PeriodicalIF":1.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perspective on the nursing management for gestational diabetes mellitus: A perspective.","authors":"Ya-Ting Fan, Xin-Hui Wang, Qing Wang, Xiao-Tong Luo, Jing Cao","doi":"10.1097/MD.0000000000041862","DOIUrl":"10.1097/MD.0000000000041862","url":null,"abstract":"<p><p>This study provides a comprehensive examination of gestational diabetes mellitus (GDM), shedding light on the geographical and ethnic variations in its prevalence. It elucidates the diagnostic evolution, noting the transition from rudimentary glucose tests to the more sophisticated Oral Glucose Tolerance Test (OGTT), which not only facilitates early detection but also standardizes screening protocols. The study delves into the evolution of GDM diagnosis, emphasizing the standardization of the OGTT and its pivotal role in enhancing early detection rates. It meticulously discusses holistic management approaches for GDM, encompassing tailored dietary interventions, prescribed physical activity, and pharmacotherapy. The need for individualized strategies to optimize glucose control is strongly emphasized. The study underscores the significance of mental health in GDM management, advocating for integrated psychological support and stress management interventions to bolster metabolic regulation. An exploration of telemedicine and artificial intelligence highlights their potential to revolutionize GDM care by enabling real-time monitoring and personalized interventions, thus improving patient outcomes. An analysis of health policies and educational efforts underscores their impact on GDM management, advocating for proactive measures to mitigate its prevalence through public health initiatives. The study identifies key research gaps and offers a focused analysis of critical advancements in GDM management, including personalized care strategies and the role of innovative technologies such as artificial intelligence and telemedicine in improving outcomes. Finally, the study calls for further research into personalized treatment modalities and innovative diagnostic tools to address existing gaps in GDM management, particularly in diverse demographic groups.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 12","pages":"e41862"},"PeriodicalIF":1.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of digital health corrective posture exercise program on head and shoulder posture in adolescents: A cluster randomized controlled trial.","authors":"Chang-Yoon Baek, Jung-Hoon Ahn, Jinyoung Lee, Hee-Hwa Lee, Woo-Taek Lim, Hye-Kang Park, Hyeong-Dong Kim","doi":"10.1097/MD.0000000000041893","DOIUrl":"10.1097/MD.0000000000041893","url":null,"abstract":"<p><strong>Background: </strong>Poor posture, particularly forward head posture and rounded shoulders, has become increasingly prevalent among adolescents due to prolonged screen use and sedentary behaviors. This study aimed to investigate the effects of a 6-week digital health corrective posture exercise (DHCPE) program on head and shoulder posture in adolescents.</p><p><strong>Methods: </strong>A total of 36 subjects were recruited and randomly allocated to 3 groups: the DHCPE group, the face-to-face exercise (FTFE) group, and a control group. The DHCPE and FTFE groups participated in the same corrective posture exercise programs. The DHCPE group conducted the digital health intervention remotely through a monitored screen, while the FTFE group engaged in corrective posture exercises on-site with therapists. Each intervention lasted 50 minutes and was conducted 3 times a week over a period of 6 weeks for both groups. The outcome measurements included protracted head and shoulder distances, trunk lean (the angle of shoulder inclination relative to the pelvis), trunk deviation, shoulder and pelvic height levels, and the absolute differences and inequality ratios between both sides. All assessments were conducted both preintervention and postintervention.</p><p><strong>Results: </strong>Both the DHCPE and FTFE groups demonstrated significant improvements in protracted head, left protracted shoulder, and trunk lean following the intervention. The interaction effect revealed that both the DHCPE and FTFE groups exhibited significant improvements in these measurements compared with the control group. Furthermore, no significant differences were found between the improvements observed in the DHCPE group and those in the FTFE group.</p><p><strong>Conclusion: </strong>DHCPE and FTFE were effective in improving head and shoulder posture in adolescents. The improvements in the DHCPE group were comparable to those achieved in the FTFE group. DHCPE has the potential to serve as a viable alternative to FTFE for enhancing head and shoulder posture in this population.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 12","pages":"e41893"},"PeriodicalIF":1.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936633/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety analysis of STA-MCA bypass combined with EDAS in the treatment of patients with moyamoya disease.","authors":"Chao Zhu, Yunhong Wang, Junnan Li","doi":"10.1097/MD.0000000000041769","DOIUrl":"10.1097/MD.0000000000041769","url":null,"abstract":"<p><p>This study evaluates the clinical efficacy and safety of superficial temporal artery to middle cerebral artery (STA-MCA) bypass combined with encephalo-duro-arterio-synangiosis (EDAS) in the treatment of moyamoya disease. A total of 80 patients with moyamoya disease who were treated at our institution between January 2022 and January 2024 were enrolled and randomly assigned to 2 groups: a control group (n = 40) and an observation group (n = 40). The control group underwent EDAS, while the observation group received STA-MCA bypass in addition to EDAS. Surgical success rates, cerebral blood flow (CBF) efficacy markers, neurological function scores, and surgical safety were comprehensively assessed in both groups. The surgical success rate in the observation group was 95.00%, significantly higher than 75.00% in the control group (P < .05). Three days postoperatively, the observation group exhibited significantly higher CBF and cerebral blood volume compared to the control group, with reduced time to peak and mean transit time (P < .05). One month after surgery, the observation group had significantly lower modified Rankin Scale and National Institutes of Health Stroke Scale scores, and higher mini-mental state examination scores compared to the control group (P < .05). The incidence of perioperative complications was 15.00% in the observation group and 17.50% in the control group, with no significant difference between the groups (P > .05). STA-MCA bypass combined with EDAS significantly improves surgical success rates, cerebral hemodynamic parameters, and neurological function outcomes in patients with moyamoya disease without increasing the incidence of surgical complications, indicating favorable safety.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 12","pages":"e41769"},"PeriodicalIF":1.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936565/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Significant correlation between serum DOTL1 levels and pain intensity, sensitivity, and psychological distress in women with fibromyalgia.","authors":"Mehmet Erdem, Tuğba Raika Kiran, Önder Otlu, Rabia Aydoğan Baykara, Feyza İnceoğlu","doi":"10.1097/MD.0000000000041966","DOIUrl":"10.1097/MD.0000000000041966","url":null,"abstract":"<p><p>Disruptor of telomeric silencing 1-like (DOT1L) is a protein involved in epigenetic regulation, as well as in the Wnt and hypoxia signaling pathways. DOT1L has been found to play a role in the pathogenesis of various diseases associated with these pathways. In this study, it was aimed to determine serum DOT1L levels in patients with fibromyalgia (FM) and its association with disease activity. Forty-eight patients diagnosed with FM according to the 2016 American College of Rheumatology criteria and 48 healthy controls were included in the study. Disease activity was measured using clinical questionnaires (Fibromyalgia Impact Questionnaire [FIQ], Visual Analog Scale [VAS], Widespread Pain Index [WPI], Symptom Severity Score [SSS], Pittsburgh Sleep Quality Index [PSQI], Fatigue Severity Scale [FSS], Hospital Anxiety Scale [HAS] and Hospital Depression Scale [HDS]) and DOT1L levels were assessed using Enzyme-Linked ImmunoSorbent Assay in all serum samples. Additionally, routine biochemical analyses were performed. Pain duration, FIQ, VAS, WPI, SSS, PSQI, FSS, HAS, and HDS were found to be statistically significant higher in FM compared to the control group (P = .001). Compared with the control group (0.53 ± 0.12 ng/mL), DOT1L concentrations were significantly higher in patients with FM (1.47 ± 0.13 ng/mL; P = .001). In the FM group, DOT1L levels also showed a positive correlation with the results of the all the clinical questionnaires (P = .001). It was found that the DOT1L measurement value has a statistically significant effect in predicting the difference between the FM and control groups (P = .022). When the cutoff value for DOT1L was set at 0.315 ng/mL, it was found to have 79% sensitivity and 71.7% specificity in detecting FM. This study highlights the potential of DOT1L as a valuable biomarker for FM diagnosis.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 12","pages":"e41966"},"PeriodicalIF":1.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936647/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of dynamic neuromuscular stabilization approach in lumbopelvic stability and gait parameters in individuals with idiopathic scoliosis: A randomized controlled trial.","authors":"Roberta Yi Li Ong, Deepak Thazhakkattu Vasu, Liow Kai Jun, Ng Jia Yuet, Mark Isaac Fernandez, Kiruthika Selvakumar, Joyce Ming Zi Goh","doi":"10.1097/MD.0000000000041905","DOIUrl":"10.1097/MD.0000000000041905","url":null,"abstract":"<p><strong>Background: </strong>Adolescent idiopathic scoliosis (AIS) is a common spinal deformity that leads to impaired lumbopelvic stability, gait dysfunction, and associated pain and psychological distress. This study evaluates the effectiveness of dynamic neuromuscular stabilization (DNS) in improving lumbopelvic stability and gait in AIS patients, comparing it to core stability exercises (CSE). This study evaluates the effectiveness of DNS in improving lumbopelvic stability and gait in AIS patients, comparing it to CSE.</p><p><strong>Methods: </strong>This randomized controlled trial involved participants aged 18 to 25 years with mild to moderate idiopathic scoliosis, who were randomly assigned to either the control or experimental group. Both groups received 12 sessions of supervised exercises over 6 weeks, with the experimental group also incorporating DNS exercises alongside CSE. Lumbopelvic stability was assessed using the single leg squat, while core stability was evaluated with the stabilizer pressure Biofeedback in combination with the Sahrmann core stability test. Additionally, gait spatiotemporal parameters and pelvic dynamics were analyzed using the BTS-G-WALK system.</p><p><strong>Results: </strong>Of 30 participants, 28 completed the study, comprising 12 males and 16 females, with 26 having mild right-sided thoracic scoliosis. Both groups showed improvement in the left single leg squat, with the control group reaching 93.3% \"Good\" performance and the experimental group achieving 69.2%. Gait analysis showed a significant reduction in duration for both groups, with the control group improving from 112.98 to 71.41 seconds (P = .005) and the experimental group improving from 112.33 to 67.68 seconds (P = .021).</p><p><strong>Conclusion: </strong>This ongoing 12-week study shows that the combined DNS and CSE approach significantly improves lumbopelvic stability in individuals with idiopathic scoliosis. However, the impact on gait parameters was minimal, possibly due to the short duration of the intervention and the similar walking strategies of those with single-curve scoliosis and healthy individuals. These findings highlight the potential of integrating DNS into scoliosis rehabilitation and underscore the need for further research to optimize treatment duration and assess long-term functional outcomes.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 12","pages":"e41905"},"PeriodicalIF":1.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936624/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of online mindfulness-based interventions on mental and physical health outcomes in cancer patients: A systematic review and meta-analysis of randomized controlled trials.","authors":"Lichun Xu, Aixuan Guan, Yuxin Huang","doi":"10.1097/MD.0000000000041870","DOIUrl":"10.1097/MD.0000000000041870","url":null,"abstract":"<p><strong>Background: </strong>To determine whether online mindfulness-based interventions (MBIs) help improve the physical and mental health of cancer patients, we conducted a systematic review and meta-analysis of relevant randomized controlled trials (RCTs).</p><p><strong>Methods: </strong>We searched PubMed, Web of Science, Scopus, Embase, Cochrane, Medline, and CINAHL databases for RCTs published up to April 31, 2023. Two reviewers selected and critically appraised the trials and extracted the data. Fourteen RCTs met the inclusion criteria.</p><p><strong>Results: </strong>A total of 14 RCTs with 1316 participants were part of this meta-analysis. The results showed that the online MBI was effective in improving the anxiety level (standardized mean difference [SMD] = -0.30, 95% confidence interval [CI] (-0.59, -0.01), P = .04), stress [SMD = -0.65, 95% CI (-1.23, -0.07), P = .03], quality of life [SMD = 0.33, 95% CI (0.17, 0.50), P < .0001], sleep quality [SMD = -0.38, 95% CI (-0.65, -0.10), P = .007], and fatigue severity [weighted mean difference (WMD) = -3.81, 95% CI (-6.11, -1.51), P = .001] in cancer patients. Not shown to affect depression [SMD = -0.19, 95% CI (-0.54, 0.17), P = .30].</p><p><strong>Conclusion: </strong>Online MBIs may be effective in the reduction of psychological distress and other symptoms in cancer patients. However, in view of the limitations of the current study, more rigorously designed RCTs will be needed in the future.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 12","pages":"e41870"},"PeriodicalIF":1.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11936609/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}