{"title":"Acid-etched monolithic translucent zirconia laminate veneer for restoring a discolored anterior tooth: A case report.","authors":"Nguyen Viet Anh, Nguyen Thi Trang, Nguyen Thi Loan","doi":"10.1097/MD.0000000000042093","DOIUrl":"10.1097/MD.0000000000042093","url":null,"abstract":"<p><strong>Rationale: </strong>Laminate veneers have become the treatment of choice for restoring tooth esthetics and function conservatively. However, due to their thin nature, the esthetic rehabilitation of discolored teeth following pulp necrosis can be challenging. Translucent zirconia offers a favorable balance between masking ability and optical translucency while maintaining high durability. To enhance the bonding strength between zirconia and adhesive agents, the treatment of the zirconia surface with strong acids has been extensively investigated in laboratory settings. However, the clinical application of this technique has not yet been published.</p><p><strong>Patient concerns: </strong>A discolored anterior incisor that had undergone endodontic treatment.</p><p><strong>Diagnosis: </strong>Discolored anterior incisor following pulp necrosis.</p><p><strong>Interventions: </strong>Restoration of the discolored anterior incisor with an acid-etched translucent zirconia veneer.</p><p><strong>Outcomes: </strong>The monolithic translucent zirconia veneer successfully restored the discolored anterior tooth. A 2-year follow-up demonstrated that the acid-etched surface ensured the long-term survival of the restoration.</p><p><strong>Lessons: </strong>Enhancing bond strength through micromechanical retention created by strong acid etching has proven effective in ensuring a secure bond between the veneer and adhesive cement, contributing to the long-term success of translucent zirconia veneers.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e42093"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
MedicinePub Date : 2025-04-04DOI: 10.1097/MD.0000000000042074
Erfan Barootchi, Sina Arefi, Pardis Zamani, Mohammad Soleimani, Amir Hossein Karimi, Reza Hajebi, Seyyed Hossein Shafiei
{"title":"The study of total hip arthroplasty outcomes among statin users in Sina Hospital, Iran.","authors":"Erfan Barootchi, Sina Arefi, Pardis Zamani, Mohammad Soleimani, Amir Hossein Karimi, Reza Hajebi, Seyyed Hossein Shafiei","doi":"10.1097/MD.0000000000042074","DOIUrl":"10.1097/MD.0000000000042074","url":null,"abstract":"<p><p>Total hip arthroplasty (THA) is a highly effective intervention for hip osteoarthritis. The increasing demand for THA is driven by an expanding pool of eligible patients, including elderly individuals with comorbidities. Statins, which are widely used to reduce cardiovascular risk, have shown potential benefits in reducing postoperative complications after joint arthroplasty. This study aims to evaluate the influence of statin use on THA outcomes and postoperative quality of life (QOL). This retrospective observational cohort study was conducted at a single center. Patients who underwent primary THA between 2015 and 2021 were identified and categorized into the statin-exposed and non-statin cohorts. Patients were interviewed regarding postoperative complications and completed the Short Form-8 questionnaire to assess their QOL. Statistical analyses were performed using t tests, Chi-square tests, and correlation tests. In total, 364 patients were included in the final sample with 37 patients in the statin-exposed cohort. The statin-exposed cohort included significantly older patients with higher comorbidity rates. However, there were no significant differences in postoperative joint or systemic complications or readmission rates between the 2 cohorts. The in-hospital mortality was lower in the statin cohort, but the difference was not statistically significant (0% vs 8.9%, P = .059). There was no significant difference between the 2 cohorts based on the Short Form-8 questionnaire (21.65 ± 8.14 vs 20.16 ± 8.67, P = .310). Contrary to previous studies, this study did not find significant differences in THA outcomes and QOL between statin-exposed and non-statin cohorts. This disparity may be a result of differences in study design, patient populations, and the timing of statin initiation relative to surgery. The findings of this study should be validated through larger studies to assess the effects of statin use more firmly.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e42074"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
MedicinePub Date : 2025-04-04DOI: 10.1097/MD.0000000000042040
Nghia Thuong Nguyen, Nga Anh Thi Nguyen, Hai Phuong Nguyen Tran, Sang Quang Ly
{"title":"Iatrogenic propagation of left main coronary artery dissection during diagnostic coronary angiography: A case report.","authors":"Nghia Thuong Nguyen, Nga Anh Thi Nguyen, Hai Phuong Nguyen Tran, Sang Quang Ly","doi":"10.1097/MD.0000000000042040","DOIUrl":"10.1097/MD.0000000000042040","url":null,"abstract":"<p><strong>Rationale: </strong>Iatrogenic dissection of the left main coronary artery (LMCA) extending to the left anterior descending (LAD) and left circumflex arteries is a very rare but catastrophic complication during coronary intervention. Prompt diagnosis and appropriate management are essential for improving patient outcomes.</p><p><strong>Patient concerns: </strong>We report the case of a 78-year-old male with a past medical history of hypertension and previous myocardial infarction who presented to the emergency department with progressively worsening angina over 2 weeks.</p><p><strong>Diagnoses: </strong>During coronary angiography, LMCA dissection occurred due to catheter manipulation. The dissection extended to both the LAD and left circumflex arteries, causing hemodynamic instability.</p><p><strong>Interventions: </strong>Using a provisional stenting strategy, the dissection was successfully treated with percutaneous transluminal coronary angioplasty and stent placement from the LMCA to the proximal and mid-LAD. Intravascular ultrasound-guided optimization confirmed appropriate stent expansion and apposition after the proximal optimization technique.</p><p><strong>Outcomes: </strong>The patient's chest pain resolved postprocedure, and he remained hemodynamically stable during a 6-month follow-up with patent stents confirmed on check angiogram.</p><p><strong>Lessons: </strong>This case highlights the importance of preventing, recognizing, and promptly managing iatrogenic LMCA dissection to prevent fatal outcomes. Intravascular ultrasound-guided optimization plays a crucial role in ensuring optimal stent placement in these high-risk emergency interventions.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e42040"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
MedicinePub Date : 2025-04-04DOI: 10.1097/MD.0000000000041760
Jiali Zhu, Jianqiang Nie
{"title":"Mendelian-based urolithiasis risk concerning fish consumption and fish oil supplement.","authors":"Jiali Zhu, Jianqiang Nie","doi":"10.1097/MD.0000000000041760","DOIUrl":"10.1097/MD.0000000000041760","url":null,"abstract":"<p><p>The link between fish consumption and urolithiasis risk has been observed in previous observational studies, yet a definitive causal relationship remains uncertain. We acquired data regarding fish consumption, fish oil supplementation, and urolithiasis from publicly available large-scale genome-wide association studies (GWAS). Urolithiasis data were sourced from the FinnGen consortium, comprising 5347 cases and 213,445 controls. Information on fish consumption and fish oil supplementation was extracted from the UK Biobank, encompassing 460,443 samples for oily fish consumption, 460,880 samples for non-oily fish consumption, and 461,384 samples for fish oil intake. We conducted 2-sample Mendelian randomization (MR) analyses employing random effects inverse variance weighting, weighted median, and MR-Egger methods, respectively. Additionally, a sensitivity analysis was executed. Our study revealed a heightened risk of urolithiasis associated with non-oily fish consumption (odds ratio [OR] = 1.78, 95% confidence interval [CI]: 1.04-3.03; P = .03), whereas no causal link was found between oily fish consumption and urolithiasis (OR = 0.92, 95% CI: 0.60-1.40; P = .69). Conversely, fish oil supplementation was linked to a diminished urolithiasis risk (OR: 0.02, 95% CI: 0-0.30; P = .005). Furthermore, our sensitivity analysis yielded no evidence of heterogeneity or pleiotropy in our MR analysis. In summary, our study, utilizing genetic data, suggests that non-oily fish consumption may increase the risk of urolithiasis formation, while fish oil supplementation may mitigate this risk.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e41760"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
MedicinePub Date : 2025-04-04DOI: 10.1097/MD.0000000000042089
Sipei Cheng, Rou Yu
{"title":"Perioperative management of cesarean section in pregnant women complicated by central core disease: A case report and literature review.","authors":"Sipei Cheng, Rou Yu","doi":"10.1097/MD.0000000000042089","DOIUrl":"10.1097/MD.0000000000042089","url":null,"abstract":"<p><strong>Rationale: </strong>The central core disease (CCD) is a relatively uncommon yet frequently encountered condition characterized by slow or nonprogressive weakness primarily affecting the proximal limbs, predominantly observed during infancy or childhood. Pregnancy combined with CCD is an exceedingly rare occurrence, which needs a multidisciplinary approach for perinatal management. However, there remains considerable debate regarding the optimal timing and methodology for pregnancy termination as well as the utilization of anesthesia or sedatives.</p><p><strong>Patient concerns: </strong>We present a case of a patient complicated by CCD, in which we also identified a family carrying a missense mutation of RYR1 (NM_000540) c.13910 C>T (exon 95), p.T4637I (heterozygous). The patient uneventfully delivered a female neonate via cesarean section under continuous epidural anesthesia.</p><p><strong>Diagnoses: </strong>The patient, a 27-year-old pregnant woman with complications of CCD and a missense mutation of RYR1, expressed the desire to terminate her pregnancy.</p><p><strong>Intervention: </strong>Multiple protocols of anesthesia management were developed based on the patient's specific condition and surgical requirements, which included scheduled surgery under neuraxial anesthesia, as well as preparation of general anesthetic drugs, dantrolene sodium, airway devices, and specialized anesthesia machines for emergencies such as cord prolapse or fetal bradycardia.</p><p><strong>Outcomes: </strong>The cesarean section went smoothly with continuous epidural anesthesia at the L3-4 and T12-L1 intervertebral space with the catheter inserted upwards at T12-L1, and downwards at L3-4. The patient and her baby were discharged after 4 days without any complications related to anesthesia.</p><p><strong>Lessons: </strong>The identification of a CCD family in our case not only contributes to a deeper understanding of anesthesia methods in CCD pregnant women but also enriches the variation database of the RYR1 gene, which is essential for conducting long-term follow-up studies.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e42089"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Takayasu arteritis: Diagnosis of a rare clinical entity: A case report.","authors":"Selemon Hileeyesus, Abilo Tadesse, Addissie Fekrie, Berhanu Shetie, Nebiyu Bekele, Guadie Beyazn, Temesgen Tadesse, Weynishet Kebede","doi":"10.1097/MD.0000000000042096","DOIUrl":"10.1097/MD.0000000000042096","url":null,"abstract":"<p><strong>Rationale: </strong>Takayasu arteritis is a rare, autoimmune, granulomatous inflammatory vascular disease of the aorta and its main branches. Delayed diagnosis was attributed to vague early clinical features, lack of specific diagnostic marker, rarity of disease, and lack of awareness by physicians of the disease condition.</p><p><strong>Patient concerns: </strong>A 28-year-old woman presented with sudden onset right sided body weakness associated with transient loss of consciousness, left-sided facial deviation, and slurring of speech. She had history of limb claudication. She was told to have rheumatic regurgitant aortic valve disease 5 years back. Physical examination revealed elevated blood pressure, reduced left radial artery pulse, faintly palpable right dorsalis pedis and posterior tibial arteries pulse, blood pressure asymmetry in arms, early diastolic murmur at erb's area, and right-sided hemiparesis with ipsilateral supra-nuclear facial palsy. Laboratory markers revealed high erythrocyte sedimentation rate. Two dimensional-transthoracic echocardiography and neck Doppler ultrasound revealed aortic regurgitation, and stenosed and thrombosed left common carotid artery, respectively. Post-contrast computed tomography showed thickened, occluded and thrombosed left common carotid artery, stenosed right common carotid artery, and thickened, stenosed and calcified descending thoracic aorta and abdominal aorta. Brain magnetic resonance imaging showed left basal ganglia infarction. Diagnosis of thromboembolic stroke secondary to Takayasu arteritis was made.</p><p><strong>Diagnoses: </strong>Diagnosis of Takayasu arteritis was settled using modified Ishikawa Diagnostic Criteria and American College of Rheumatology Classification Criteria.</p><p><strong>Interventions: </strong>She was started on glucocorticoids 50 mg po daily for 3 months and tapered by 5 mg po weekly over 3 months, azathioprine 100 mg po daily, aspirin 81 mg po daily, atorvastatin 40 mg po daily, amlodipine 10 mg po daily, and cotrimoxazole 960 mg po trice weekly. Physical therapy was continued.</p><p><strong>Outcomes: </strong>The patient showed marked symptomatic improvement after 3 months of treatment. She was referred to higher health institution for evaluation of vascular intervention.</p><p><strong>Lessons: </strong>High index of clinical suspicion is required for early diagnosis of rare diseases to prevent adverse outcomes.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e42096"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
MedicinePub Date : 2025-04-04DOI: 10.1097/MD.0000000000042086
Xiaoping Shi, Yanxing Lv, Yongjiang Jiang, Pianpian Pan, Yueju Cai
{"title":"X-linked dominant chondrodysplasia punctata due to novel mutation in EBP gene: A case report.","authors":"Xiaoping Shi, Yanxing Lv, Yongjiang Jiang, Pianpian Pan, Yueju Cai","doi":"10.1097/MD.0000000000042086","DOIUrl":"10.1097/MD.0000000000042086","url":null,"abstract":"<p><strong>Rationale: </strong>Chondrodysplasia punctata is a rare hereditary disorder that affects bone development. The disease is primarily caused by mutations in the emopamil binding protein (EBP) gene, leading to X-linked dominant metabolic enzyme abnormalities. This study aims to report a novel EBP mutation in X-linked dominant chondrodysplasia punctata type 2 (CDPX2), expanding the genetic spectrum of the disease and highlighting the critical role of combined clinical and genetic diagnosis in guiding prenatal counseling and postnatal management.</p><p><strong>Patient concerns: </strong>Multiple prenatal ultrasounds revealed misalignment of the spinal column and short femur. Postnatally, the infant exhibited craniofacial defects, short limbs, congenital ichthyosis, and alopecia.</p><p><strong>Diagnoses: </strong>Radiographic examination revealed multiple punctate calcifications bilaterally in the pyramids, ischium, pubis, and calcaneus. Whole-exome sequencing of the family revealed a heterozygous mutation, c.204G>A (p.Trp68Ter), in the EBP gene in the affected infant, which is a new pathogenic mutation.</p><p><strong>Interventions: </strong>The infant received continuous positive airway pressure support for respiratory distress, which was discontinued after 7 days due to clinical improvement.</p><p><strong>Outcomes: </strong>At discharge, respiratory status was stable. Follow-up at 3 months showed significant growth delay: weight 4.6 kg (<3rd percentile) and length 54.5 cm (9th percentile).</p><p><strong>Lessons: </strong>This case underscores that meticulous physical examination combined with genetic analysis is critical for diagnosing CDPX2. Early identification of EBP mutations enables accurate prenatal counseling and risk assessment for future pregnancies.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e42086"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
MedicinePub Date : 2025-04-04DOI: 10.1097/MD.0000000000041850
Yisi Zhang, Xiaoguang Chen, Songbin Pan
{"title":"Misdiagnosis of spinocerebellar ataxia type 3 as persistent postural-perceptual dizziness: A case report.","authors":"Yisi Zhang, Xiaoguang Chen, Songbin Pan","doi":"10.1097/MD.0000000000041850","DOIUrl":"10.1097/MD.0000000000041850","url":null,"abstract":"<p><strong>Rationale: </strong>Spinocerebellar ataxia type 3 (SCA3) is the most common autosomal dominant inherited spinocerebellar disorder. The disease can easily be misdiagnosed because the symptoms of SCA3 are diverse and not obvious in the early stages.</p><p><strong>Patient concerns: </strong>A 55-year-old woman had experienced dizziness and an unstable gait since 2017. She was misdiagnosed with persistent postural-perceptual dizziness at another hospital because of normal brain magnetic resonance imaging and emotional abnormalities. In our hospital, there were no abnormalities in routine laboratory tests and brain magnetic resonance imaging, but various examinations showed peripheral and central vestibular dysfunction. She had a typical family history of dizziness and an unstable gait.</p><p><strong>Diagnoses: </strong>The patient was diagnosed with SCA3 by genetic testing.</p><p><strong>Interventions: </strong>The patient underwent a regimen of betahistine therapy combined with vestibular rehabilitation training.</p><p><strong>Outcomes: </strong>The patient exhibited clinical improvement and was discharged after 2 weeks.</p><p><strong>Lessons: </strong>Detailed neuro-otological and neuro-ophthalmological evaluations are helpful for the diagnosis of patients with suspected cerebellar ataxia.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e41850"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
MedicinePub Date : 2025-04-04DOI: 10.1097/MD.0000000000042068
İsmail Tirnova, Maya Gasimova, Behlül Igus, Alpay Yeşilaltay, Derya Kaşkari, Saime Ramadan, Ahmet Serdar Karaca
{"title":"Portal vein thrombosis after laparoscopic appendectomy for acute appendicitis: A case report.","authors":"İsmail Tirnova, Maya Gasimova, Behlül Igus, Alpay Yeşilaltay, Derya Kaşkari, Saime Ramadan, Ahmet Serdar Karaca","doi":"10.1097/MD.0000000000042068","DOIUrl":"10.1097/MD.0000000000042068","url":null,"abstract":"<p><strong>Rationale: </strong>Portal vein thrombosis (PVT) has a complex pathophysiologic pathway and may cause life-threatening clinical complications. Malignancies, hepatic cirrhosis, auto-immune disorders, previous splenectomy, and other causes of thrombocytosis (over 1,000,000/mL) are the most common causes of PVT. On the other hand, hematologic disorders and infectious processes in the abdominal cavity may cause PVT uncommonly. We present a case of PVT following acute appendicitis and laparoscopic appendectomy in this report.</p><p><strong>Patient concerns: </strong>A 32-year-old male was admitted to our emergency room due to lower quadrant pain and vomiting. Acute appendicitis was diagnosed and after a routine laparoscopic appendectomy, the patient was discharged. The patient was admitted to the emergency room with nonspecific epigastric pain on postoperative day 30.</p><p><strong>Diagnoses: </strong>Portal vein thrombosis was diagnosed by computed tomography. Hematologic investigations revealed a homozygous mutation of the methylene tetrahydrofolate 1298 gene.</p><p><strong>Interventions: </strong>Immediate low-molecular-weight heparin administration was initiated. The gastrointestinal system council and interventional radiology team opted for a medical approach and converted the low-molecular-weight heparin to apixaban.</p><p><strong>Outcomes: </strong>The computed tomography revealed the complete resolution of the thrombus on postoperative day 100.</p><p><strong>Lessons: </strong>Laparoscopic appendectomy can be complicated by portomesenteric axis thrombosis. When unusual findings are encountered during the postoperative follow-up period, rapid and detailed examinations should be performed.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e42068"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
MedicinePub Date : 2025-04-04DOI: 10.1097/MD.0000000000042075
Nazire Kilic Safak, Zekiye Karaca Bozdag, Ayca Pamukcu, Ozkan Oguz
{"title":"Clinical importance of the relationship between parietal foramen variations and the sagittal suture.","authors":"Nazire Kilic Safak, Zekiye Karaca Bozdag, Ayca Pamukcu, Ozkan Oguz","doi":"10.1097/MD.0000000000042075","DOIUrl":"10.1097/MD.0000000000042075","url":null,"abstract":"<p><p>This study aims to determine the prevalence, number, and localization of the parietal foramen in relation to the sagittal suture. Forty skulls (80 parietal bones), whose age and sex were unknown, from the Department of Anatomy, Faculty of Medicine, Cukurova University, were studied. Morphometric measurements were performed using a digital caliper. The presence of the parietal foramen and its number, localization, and distance from the sagittal suture were evaluated in this study. SPSS v.20 software was used for statistical analysis. In addition to descriptive statistical methods, the Mann-Whitney U-test was used to evaluate the quantitative data. The parietal foramen was not detected in 19 skulls (47.5%) but was observed unilaterally in 10 skulls (25%) and bilaterally in 11 skulls (27.5%). The parietal foramen was detected in 32 parietal bones (40%). Furthermore, it was observed as single in 30 parietal bones (37.5%) and as double in 2 parietal bones (2.5%); however, the triple parietal foramen was not detected. There were no double foramens in the right parietal bone. The foramen was not observed in 48 (60%) of the parietal bones. The mean distance between the parietal foramen and sagittal suture was as 7.42 ± 5.64 mm. No statistically significant differences were detected between the parietal foramina in terms of their distances to the sagittal suture on either the right or left side (P > .05). Knowledge of the localization of the parietal foramen and its relationship with the sagittal suture helps understand the relationship between the dural venous sinuses and scalp veins. Furthermore, an understanding of these variations may aid in the detection of congenital anomalies. We believe that the results of this study will contribute important morphometric data for anatomists and clinicians.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e42075"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}