Medicine最新文献

{"title":"A comparative study of doctor's meaning construction in diagnostic discourse with different degrees of patient satisfaction: A review.","authors":"Haiying Liang, Caihong Wang","doi":"10.1097/MD.0000000000042528","DOIUrl":"10.1097/MD.0000000000042528","url":null,"abstract":"<p><p>Drawing on the theory of ideational meaning construction in Systemic Functional Linguistics, and using 22,945 words of 4 doctor's outpatient doctor-patient interaction as its data resource, the paper makes a comparative analysis of doctors' meaning construction in their diagnostic discourse via transitivity system employed by doctors with higher patient satisfaction and those with lower patient satisfaction. The results show that doctors with higher patient satisfaction choose more behavioral process, attribute and extent, in the process type, participants, and circumstantial elements respectively, indicating they pay more attention to the detailed information of the disease and patients' daily life in order to give more accurate diagnosis and relieve the pressure of the patients. By contrast, doctors with lower patient satisfaction employ fewer behavioral process, more goal, and more manner, cause and contingency, suggesting they pay less attention to patients' condition and the degree of patients' acceptance and participation, instead emphasizing their authority in medicine and the way of treatment. The research findings offer reference to the harmonious relationship establishment between the doctor and the patient.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 21","pages":"e42528"},"PeriodicalIF":1.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12113918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Length of stay and comorbidity prevalence among individuals with chronic obstructive pulmonary disease in a tertiary care healthcare center in Saudi Arabia; A cross-sectional study.","authors":"Tareq F Alotaibi, Fatmah Othman, Bayan A Alrasheed, Battol M Aldraiwish, Manar M Alharthi, Hessah G Alotaibi, Abdulrhman S Alghamdi, Hassan Aljohani, Mohammed M Alqahtani, Taha T Ismaeil, Mobarak K Alqahtani, Nouf N Alotaibi, Khalid S Alwadeai, Saleh S Algarni, Abdullah M M Alanazi","doi":"10.1097/MD.0000000000041855","DOIUrl":"10.1097/MD.0000000000041855","url":null,"abstract":"<p><p>Chronic obstructive pulmonary disease (COPD) is a major cause of mortality, morbidity, and high healthcare costs. While previous studies have addressed the burden of COPD at the national level, there is a lack of current data examining the prevalence of COPD with comorbidities as a predictor for hospital length of stay (LOS). This study aimed to investigate the average LOS and its predictors among patients with COPD admitted to a tertiary healthcare center. A cross-sectional study was conducted in a tertiary care healthcare center in Saudi Arabia between 2017 and 2022. Adult patients with a primary COPD diagnosis admitted at least once to the medical department during the study period were identified. Data on the demographics and co-existing comorbidities were extracted from the electronic medical records of each patient. The main outcome was the LOS among admitted patients. Linear regression analysis was conducted to examine COPD predictors among the demographic and clinical variables. This study involved 629 patients diagnosed with COPD, primarily females, with a mean age of 74 years. The median length of hospital stay was 5 days, and hypertension was the most common comorbidity among the participants (78.8%). The hospital LOS of male patients was expected to be 1.30 days longer than that of female patients (95% confidence interval, 0.15-2.77), and the hospital LOS of patients with cancer was expected to be 3 days longer than that of patients without cancer (B coefficient, 2.73; 95% confidence interval, 0.78-5.37). Male sex and cancer were strong predictors of prolonged hospitalization among patients with COPD. These findings highlight the need for healthcare providers to observe the presence of these comorbidities when managing COPD in patients to reduce their hospital stay.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 21","pages":"e41855"},"PeriodicalIF":1.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12113970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of a nomogram to predict symptomatic intracranial hemorrhage following endovascular treatment in acute ischemic stroke: A single center retrospective, observational study.","authors":"Lvjie Shen, Bintao Jin, Cao Jiang, Jianqiang Yu, Shuxing Li, Yunhui Wang","doi":"10.1097/MD.0000000000042495","DOIUrl":"10.1097/MD.0000000000042495","url":null,"abstract":"<p><p>Symptomatic intracranial hemorrhage (SICH) is a severe post-endovascular treatment (EVT) complication of acute ischemic stroke, leading to high morbidity, mortality, and neurological deficits. However, despite these risk factors, there is currently no clinically accepted predictive model to predict SICH risk in EVT patients. This study aimed to identify independent perioperative risk factors for SICH and to provide a new nomogram-based predictive model for large vessel occlusion patients. This study retrospectively examined 127 acute ischemic stroke patients receiving EVT from the First Affiliated Hospital of Wenzhou Medical University. Inclusion criteria included the National Institutes of Health Stroke Scale (NIHSS), Alberta Stroke Program Early CT Score (ASPECTS), and American Society of Interventional and Therapeutic Neuroradiology/Society of Interventional Radiology (ASITN/SIR) collateral scores. Using these predictors, a logistic regression model was used to generate the NIHSS/ASPECTS/ASITN (NAA) nomogram. The predictive ability was measured with the area under the receiver operating characteristic curve and calibration plots. Our data demonstrated that SICH patients had significantly higher baseline NIHSS scores (median: 22.38 vs 15.03; P < .001), ASPECTS (median: 5.89 vs 7.69; P < .001), and ASITN/SIR scores (median: 1.62 vs 2.69; P < .001). The NAA nomogram exhibited an area under the receiver operating characteristic curve value of 0.845 (95% confidence interval: 0.763-0.928), which is superior to the predictive performance. Calibration plots were robust in predicting and observing values. The NAA nomogram is a robust predictor of SICH after EVT that is more accurate than any scoring system. More external validation is needed to make it generalizable to diverse clinical settings.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 21","pages":"e42495"},"PeriodicalIF":1.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12114011/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aberrant obturator artery or corona mortis embolization for the treatment of pelvic trauma hemorrhage: Technique and clinical outcomes.","authors":"Yook Kim, Eic Ju Lim","doi":"10.1097/MD.0000000000042491","DOIUrl":"10.1097/MD.0000000000042491","url":null,"abstract":"<p><p>This study aims to assess the safety and efficacy of transcatheter arterial embolization (TAE) of the corona mortis in the aberrant obturator artery (AOA) for the management of bleeding in blunt pelvic trauma. This retrospective analysis included data on 14 patients (mean age, 68.6; range, 34-85 years) who underwent TAE of the corona mortis for managing hemorrhage following pelvic fracture from September 2018 to March 2023. Medical records' data included clinical manifestation, injury severity score, hemodynamic stability, length of stay in intensive care unit, transfusion requirement, complications related to the TAE, and clinical outcomes. Of 14 patients that underwent abdominopelvic computed tomography before the TAE, 12 demonstrated positive imaging findings for bleeding including pseudoaneurysm and contrast media extravasation. Thirteen exhibited ipsilateral fracture of the superior ramus fracture, all had a positive sign of bleeding and underwent super-selective TAE of the corona mortis to control the bleeding. Overall, technical success was achieved in all 14. None of the patients demonstrated any procedure-related complications. TAE of the corona mortis is a safe and effective method for controlling hemorrhage following pelvic bone fractures. In particular, fractures involving the superior pubic ramus or pubic acetabulum warrant close attention to bleeding from the AOA, known as the corona mortis.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 21","pages":"e42491"},"PeriodicalIF":1.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12113967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An infant with IVIG-resistant Kawasaki disease requiring repeated glucocorticoids therapy: A case report and literature review.","authors":"Yifan Ren","doi":"10.1097/MD.0000000000042572","DOIUrl":"10.1097/MD.0000000000042572","url":null,"abstract":"<p><strong>Rationale: </strong>Kawasaki disease (KD) is an acute systemic vasculitis predominantly affecting children, characterized by fever, chapped lips, strawberry tongue, conjunctival hyperemia, rash, and cervical lymphadenopathy. The most severe complication associated with KD is the development of coronary artery abnormalities.</p><p><strong>Patient concerns: </strong>A 1-year and 2-month-old girl was admitted to the hospital with persistent fever, rash, and elevated inflammatory markers.</p><p><strong>Diagnoses: </strong>Despite 36 hours of intravenous immunoglobulin (IVIG) therapy, she remained febrile and was classified as IVIG-resistant.</p><p><strong>Interventions: </strong>Methylprednisolone was administered for 13 days; however, tapering to a single daily dose resulted in symptom recurrence.</p><p><strong>Outcomes: </strong>A subsequent course of intravenous methylprednisolone, administered over 42 days, resolved her symptoms, with follow-up evaluations demonstrating normal echocardiograms and electrocardiograms. The duration of methylprednisolone treatment exceeded standard guideline recommendations for KD; however, the patient achieved full recovery without adverse effects.</p><p><strong>Lessons: </strong>This case highlights the potential efficacy of glucocorticoids as a treatment option for IVIG-resistant KD and emphasizes the necessity for further research into their role as first-line therapy, particularly in patients with IVIG intolerance.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 21","pages":"e42572"},"PeriodicalIF":1.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12113926/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The positive role of Chinese herbal medicine as an adjunctive therapy for refractory gastroesophageal reflux disease: A systematic review and network meta-analysis.","authors":"Ruiting Zhang, Zhenyu Yang, Xiangbin Pan, Yingzhe Liu, Qiusi Huang, Zexi Song, Qianqian Yao, Dongxia Li, Yuan Zhang","doi":"10.1097/MD.0000000000042565","DOIUrl":"10.1097/MD.0000000000042565","url":null,"abstract":"<p><strong>Background: </strong>Proton pump inhibitors are currently the primary treatment option for refractory gastroesophageal reflux disease (rGERD), yet they have limitations, including poor efficacy and potential adverse events. Chinese herbal medicine (CHM) may offer an effective and safe adjunctive therapy.</p><p><strong>Methods: </strong>This network meta-analysis investigate the adjunctive therapeutic effect and safety of CHM on rGERD. Randomized controlled trials (RCTs) of CHM combined with conventional Western medicine in the treatment of rGERD added to 8 online databases from its inception to January 2024 were systematically searched. Review Manager 5.3 and and Stata 14.0 software were used to conduct pairwise meta-analysis and network meta-analysis of RCTs that met the inclusion criteria. In addition, the methodological quality of RCTs was analyzed using the Cochrane Collaboration Risk of Bias ROB 2.0 assessment tool. This study was registered in PROSPERO (International Prospective Register of Systematic Reviews) (CRD42024532264).</p><p><strong>Results: </strong>This study included a total of 19 RCTs, comparing 16 CHMs. Pairwise meta-analysis indicated that CHM combined with conventional Western medicine outperformed the latter in terms of overall clinical efficacy, recurrence rate, and symptom improvement. Network meta-analysis suggested that Shugan Jieyu Capsule may significantly enhance overall clinical efficacy, while Buzhongyiqi Granules may significantly reduce the recurrence rate, Sanji Powders may significantly improve symptoms of acid reflux, Shugan Jieyu Capsule may significantly improve symptoms of heartburn, and Shugan Jianpi Hewei Decoction may significantly improve symptoms of esophageal chest pain, Qingweishu Granules may significantly improve the frequency scale for the symptoms of GERD score. No serious adverse events were reported in any of the RCTs.</p><p><strong>Conclusion: </strong>The findings of this study indicate that CHM offers a positive adjunctive therapeutic benefit for rGERD; however, it is imperative to enhance the quality of future RCTs to validate these preliminary findings.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 21","pages":"e42565"},"PeriodicalIF":1.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12113975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Where did the attack come from? The mysterious case of paralysis mimicking Guillain-Barré syndrome: Case report.","authors":"Wiktor Wagner, Michał Krawiec, Adam Iwanicki, Paweł Krupa, Barbara Gębka-Kępińska, Mateusz Lubiński, Szymon Białka","doi":"10.1097/MD.0000000000042118","DOIUrl":"10.1097/MD.0000000000042118","url":null,"abstract":"<p><strong>Rationale: </strong>Tick-borne encephalitis (TBE) can present with neurological symptoms mimicking Guillain-Barré syndrome (GBS), posing a significant diagnostic challenge. Misidentification may lead to delayed or inappropriate treatment, increasing the risk of complications.</p><p><strong>Patient concerns: </strong>A 49-year-old man presented with flu-like symptoms and progressive paralysis of the left upper limb following a tick bite. His condition rapidly deteriorated despite initial therapy, including facial nerve palsy, further paralysis of the left upper limb, and swallowing difficulties.</p><p><strong>Diagnoses: </strong>The initial clinical picture, cerebrospinal fluid analysis showing elevated protein, and electromyography suggested GBS.</p><p><strong>Interventions: </strong>The patient underwent 6 plasmapheresis sessions for suspected GBS, with no neurological improvement.</p><p><strong>Outcomes: </strong>Due to a lack of improvement and further magnetic resonance imaging findings, a repeated lumbar puncture and serological testing revealed the correct diagnosis of TBE, confirmed by the presence of IgM and IgG antibodies against the TBE virus. After stabilization and intensive care unit discharge, the patient was transferred to a neurology ward and later to a rehabilitation unit. Significant neurological improvement was observed, although partial left upper limb paresis and facial nerve palsy persisted. He was eventually discharged with continued outpatient neurology and cardiology follow-up.</p><p><strong>Lessons: </strong>This case highlights the importance of detailed medical history, including tick exposure, and maintaining a broad differential diagnosis in acute flaccid paralysis. Early consideration of infectious etiologies, particularly in endemic regions, is essential to prevent unnecessary interventions and improve patient outcomes.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 21","pages":"e42118"},"PeriodicalIF":1.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12114061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A young female patient with ventricular septal defect complicated with patent foramen ovale complicated with acute cerebral infarction: A case report.","authors":"Jiaqi Wang, Huiliang Liu, Man Gao, Feifei Zhang, Yi Dang, Xiaoyong Qi","doi":"10.1097/MD.0000000000042035","DOIUrl":"10.1097/MD.0000000000042035","url":null,"abstract":"<p><strong>Rationale: </strong>Ventricular septal defect (VSD) is the most common non-cyanotic congenital heart disease. Patent foramen ovale (PFO) is a common benign lesion in healthy people.</p><p><strong>Patient concerns: </strong>The main symptoms are intermittent dizziness and headache, and weakness in the right limb. Echocardiography showed VSD and PFO, and imaging showed cerebral infarction.</p><p><strong>Diagnoses: </strong>Typical clinical manifestations, echocardiography found VSD, PFO, and imaging examination suggested cerebral infarction, indicating the diagnosis of VSD, PFO, and old cerebral infarction.</p><p><strong>Interventions: </strong>Surgical treatment includes closure of VSD and percutaneous closure of PFO, as well as anticoagulation and other related drugs.</p><p><strong>Outcomes: </strong>Since discharge, the patient's speech impairment and right limb weakness have returned to normal without any discomfort.</p><p><strong>Lessons: </strong>We report a patient with VSD complicated with PFO complicated with cerebral infarction. This case highlights the importance of understanding the specific pathological changes in patients with VSD combined with PFO for treatment and prognosis.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 21","pages":"e42035"},"PeriodicalIF":1.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12113914/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of educational attainment on gestational diabetes mellitus is mediated by body mass index: A Mendelian randomization study.","authors":"Shengjiao Zhu, Ruifeng Gui, Jiao Mu, Kun Tong, Guoqiang Chen","doi":"10.1097/MD.0000000000042008","DOIUrl":"10.1097/MD.0000000000042008","url":null,"abstract":"<p><p>Gestational diabetes mellitus (GDM) is a common pregnancy complication associated with adverse maternal and neonatal outcomes. While numerous studies have investigated the factors influencing GDM, the relationship between educational attainment and the GDM risk remains less explored. This study employs a Mendelian randomization (MR) approach to estimate the causal relationship between educational attainment, as a proxy for socioeconomic inequality, and the risk of GDM, and to quantify the roles of body mass index (BMI) as a potential mediator. We performed a two-sample MR study of genetically predicted educational attainment (instrumented using 1271 variants from 766,345 individuals) and gestational diabetes mellitus (116,363 individuals) using the largest genome-wide association studies. We used a two-step MR to quantify the proportion of education's effect on GDM mediated by BMI (681,275 individuals). Each standard deviation increase in educational attainment (4.2 years of schooling) was protective of GDM (odds ratios: 0.67; 95% confidence intervals [CI]: 0.59, 0.76). Higher educational attainment was also protective for BMI [β = -0.27 standard deviation (~1.3 kg/m2); 95% CI: -0.32, -0.22]. BMI mediated 35% (95% CI: 25%, 46%) of the total effect of education on GDM. Higher educational attainment has a protective effect on GDM risk. Interventions to reduce excess adiposity at the population level may reduce this risk, but the effect of education on GDM remains largely unexplained. Further investigation is necessary to identify additional risk factors that function as potentially modifiable mediators.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 21","pages":"e42008"},"PeriodicalIF":1.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12113916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early versus delayed surgery for sciatica: A single-center observational study.","authors":"Jingmao Zheng, Zhipeng Zhu, Zhaolin Xie, Zhilin Cheng, Tianpei Chen, Qinmian Wu, Ying Li","doi":"10.1097/MD.0000000000042479","DOIUrl":"10.1097/MD.0000000000042479","url":null,"abstract":"<p><p>Lumbar discectomy can improve symptoms of sciatica caused by lumbar disc herniation (LDH) faster than conservative treatment. However, the optimal timing of surgery for LDH has scarcely been explored. The prospectively collected clinical outcome data from patients who underwent microdiscectomy for sciatica due to LDH were retrospectively analyzed. Patients were divided into 2 groups according to the duration of sciatica before surgery: early surgery (<6 months); and delayed surgery (≥6 months). Visual analog scale (VAS) scores for low back pain (LBP), leg pain (LP), and Oswestry disability index (ODI) were compared between the 2 groups preoperatively, and at 1, 3, 6, and 12 months postoperatively. In total, 122 and 115 patients comprised the early and delayed surgery groups, respectively. There were no significant differences between the 2 groups in terms of sex, age, body mass index, comorbidities, surgical procedure, surgical segment, preoperative LBP, LP VAS scores, or ODI. A significantly higher proportion of patients in the delayed surgery group were prescribed opioids preoperatively versus those in the early surgery group (25.2% vs 10.7%, respectively; P = .003). The duration of sciatica was significantly shorter in the early surgery group than that in the delayed surgery group (3.9 vs 12.2 months; P < .001). LBP VAS scores were significantly lower in the early versus delayed surgery group at 1 and 3 months postoperatively. Additionally, LP VAS scores and ODI in the early surgery group were significantly lower than those in the delayed surgery group at 1 month postoperatively. There was no significant difference in complication rates between the 2 groups (5.7% vs 5.2%; P = .860). Compared with delayed surgery, early surgery improved pain and disability in patients diagnosed with sciatica. However, this advantage tended to decline over time postoperatively, resulting in comparable long-term outcomes.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 21","pages":"e42479"},"PeriodicalIF":1.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12113973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}