Medicine最新文献

{"title":"Assessing the timing of amniotomy after Foley balloon catheter removal in women with labor induction: The role of Bishop score: An observational study.","authors":"Yun He, Yu Tao, Qin Ni, Zhuoyue Li, Ying Huang, Lanhua Liu","doi":"10.1097/MD.0000000000041068","DOIUrl":"10.1097/MD.0000000000041068","url":null,"abstract":"<p><p>The timing of amniotomy after the Foley balloon catheter removal is crucial for successful labor induction. This study aimed to assess the effects of the Bishop score on the timing of amniotomy in patients undergoing labor induction after the Foley balloon catheter removal. This was a retrospective cohort study based on electronic medical records. We performed a Chester sampling in patients with singleton-term pregnancies who initially underwent cervical ripening using a Foley balloon catheter at the Obstetrical Department of Taixing People's Hospital from January 2023 to July 2023. A total of 889 patients were admitted to the study. After excluding 330 patients according to the exclusion criteria, 103 patients were included. Following the Foley balloon removal, an amniotomy with a Bishop score < 6 was defined as an amniotomy with an unfavorable Bishop score (n = 62), and an amniotomy with a Bishop score ≥ 6 was defined as an amniotomy with a favorable Bishop score (n = 41). The primary outcome was the incidence of cesarean delivery and the interval from induction to delivery. The secondary outcomes included the incidence of operative vaginal delivery, intrapartum hemorrhage, postpartum hemorrhage, infection, thrombosis, and neonatal outcomes. All statistical comparisons were analyzed by GraphPad Prism 9. All data were presented as the mean ± SD or percentage. Statistical analysis comparing both groups was performed using the t test, chi-square test, or Fisher exact test where appropriate. The baseline data, operative vaginal delivery rate, postpartum hemorrhage rate, infection rate, thrombosis rate, intrapartum and postpartum hemorrhage volume, and neonatal outcomes showed no significant differences between the 2 groups. However, the cesarean delivery rate, interval from induction to delivery, and hemoglobin postdelivery decline were significantly decreased in the favorable Bishop score group. Amniotomy with a favorable Bishop score after Foley balloon catheter removal is linked to lower cesarean delivery rates, shorter induction-to-delivery intervals, and less postdelivery hemoglobin decline without increasing adverse maternal or neonatal outcomes.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"103 51","pages":"e41068"},"PeriodicalIF":1.3,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11666173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonstenotic carotid artery plaques on computed tomography angiography in embolic stroke of undetermined source.","authors":"Mustafa Demir, Aslihan Semiz-Oysu, Eda Ozsezen, Yunus Yasar","doi":"10.1097/MD.0000000000040880","DOIUrl":"10.1097/MD.0000000000040880","url":null,"abstract":"<p><p>This study aims to evaluate the role of <50% stenotic cervical carotid artery plaques in embolic stroke of undetermined source (ESUS), focusing on plaque characteristics in symptomatic versus asymptomatic carotid arteries (contralateral). In this cross-sectional observational study, 81 patients who met the diagnostic criteria for ESUS and underwent were retrospectively analyzed. Carotid plaques causing <50% stenosis were examined, noting features such as plaque thickness, degree of luminal stenosis, irregularity, ulceration, calcification, and hypodensity. These characteristics were compared between the ipsilateral and contralateral carotid arteries. The study involved 33 men and 48 women, with plaques ≥3mm thick significantly more common in the ipsilateral carotid arteries (P < .05). Notable features such as plaque ulceration, irregularity, noncalcified plaque, and hypodensity were significantly more frequent ipsilaterally (P < .05). Of the plaque patients, 54.3% (44/81) were on the ipsilateral side, compared to 29.6% (24/81) on the contralateral side (P = .0024). Our findings underscore the potential significance of non-stenotic carotid plaques in ESUS. These plaques, especially those with certain high-risk characteristics, are more prevalent ipsilaterally and should be considered in clinical evaluations and treatment of ESUS.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"103 51","pages":"e40880"},"PeriodicalIF":1.3,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11666202/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"S100A11 is a potential prognostic biomarker and correlated with tumor immunosuppressive microenvironment in glioma.","authors":"Jikang Fan, Xuya Wang, Xuejun Yang","doi":"10.1097/MD.0000000000040701","DOIUrl":"10.1097/MD.0000000000040701","url":null,"abstract":"<p><strong>Background: </strong>This study investigates the role of S100A11 as a potential biomarker for glioma-associated macrophages (GAMs) and its correlation with GAMs infiltration in glioblastoma multiforme, aiming to better understand the immune microenvironment of glioma.</p><p><strong>Methods: </strong>We conducted a comprehensive study using various techniques and approaches. First, we examined the expression of S100A11 on GAMs through Western blot, immunohistochemistry, and immunofluorescence analyses. Additionally, we utilized single-cell sequencing data and immune infiltration analysis to establish the relationship between S100A11 and GAMs infiltration in glioma.</p><p><strong>Results: </strong>Our findings revealed that S100A11 was highly expressed on GAMs, as validated by Western blot, immunohistochemistry, and immunofluorescence. Moreover, S100A11 exhibited a strong correlation with GAMs infiltration, as evidenced by single-cell data and immune infiltration analysis. These results highlight the significant association of S100A11 with the immune microenvironment surrounding glioma.</p><p><strong>Conclusion: </strong>S100A11 emerges as a promising candidate for regulating glioma immunosuppression and may serve as a potential marker for GAMs. This study sheds light on the crucial role of S100A11 in the crosstalk between GAMs and glioma cells, contributing to our understanding of glioma progression within the tumor microenvironment.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"103 51","pages":"e40701"},"PeriodicalIF":1.3,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11666167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic variation and clinical phenotype analysis of hypermethioninemia caused by MAT1A gene mutation: Case report.","authors":"Jialin Mu, Yulin Li, Meng Sun, Panpan Li, Jingyun Wang, Hui Zou","doi":"10.1097/MD.0000000000040957","DOIUrl":"10.1097/MD.0000000000040957","url":null,"abstract":"<p><strong>Rationale: </strong>The high clinical heterogeneity of hypermethioninemia caused by MAT1A gene defects has resulted in a paucity of studies examining the association between clinical phenotypes, biochemical characteristics, and gene mutations in this patient group. Furthermore, the indications for therapeutic interventions in patients remain unclear. The objective of this study is to provide a foundation for clinical diagnosis, genetic counseling, and follow-up management of hypermethioninemia caused by MAT1A gene defects.</p><p><strong>Patient concerns: </strong>A retrospective analysis of children with hypermethioninemia at Jinan Maternal and Child Health Hospital from January 2016 to December 2023 was performed using tandem mass spectrometry (MS/MS). The screened and diagnosed children were tested for gene mutations using second-generation sequencing technology and confirmed using Sanger sequencing.</p><p><strong>Diagnoses: </strong>Newborn MS/MS screening for diseases demonstrated an elevated methionine level, which was outside the reference range. Upon recalling the newborns, the methionine levels remained elevated, necessitating further refinement of genetic testing. Ultimately, genetic testing confirmed hypermethioninemia, which was attributed to a mutation in the MAT1A gene.</p><p><strong>Interventions: </strong>The intervention for the patients in this study took the following forms: regular follow-up without treatment (n = 3), intake of methionine-free milk powder without any medication (n = 4), intake of methionine-free milk powder with some medication, and eventually liver transplantation (n = 1).</p><p><strong>Outcomes: </strong>A total of 14 mutation types were detected, including 3 compound heterozygous mutation types (c.926G > T, c.37_38delCT, and c.316G > A) that have not been previously reported. One patient had monoheterozygous mutations, including the novel mutation c.550-1G > A. Eight cases were monitored over time, 7 of which demonstrated typical growth and development. One infant with growth retardation was fed a special formula lacking methionine. The patient underwent liver transplantation. Subsequent follow-up examinations showed methionine and homocysteine levels within normal limits and no further neurological manifestations.</p><p><strong>Lessons: </strong>Compound heterozygous mutations c.874C > T and c.896G > A may result in higher levels of methionine, affecting the central nervous system. For newborns with initial methionine levels of >500 µmol/L, treatment with a low-Met diet is recommended. Liver transplantation may be beneficial for children with severe hypermethioninemia, particularly in preventing central nervous system damage.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"103 51","pages":"e40957"},"PeriodicalIF":1.3,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11666203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survival analysis of clear cell renal cell carcinoma based on radiomics and deep learning features from CT images.","authors":"Zhennan Lu, Sijia Wu, Dan Ni, Meng Zhou, Tao Wang, Xiaobo Zhou, Liyu Huang, Yu Yan","doi":"10.1097/MD.0000000000040723","DOIUrl":"10.1097/MD.0000000000040723","url":null,"abstract":"<p><strong>Purpose: </strong>To create a nomogram for accurate prognosis of patients with clear cell renal cell carcinoma (ccRCC) based on computed tomography images.</p><p><strong>Methods: </strong>Eight hundred twenty-two ccRCC patients with contrast-enhanced computed tomography images involved in this study were collected. A rectangular region of interest surrounding the tumor was used to extract quantitative radiomics and deep-learning features, which were filtered by Cox proportional hazard regression model and least absolute shrinkage and selection operator. Then the selected features formed a fusion signature, which was assessed by Cox proportional hazard regression model method, Kaplan-Meier analysis, receiver operating characteristic curves, and concordance index (C-index) in different clinical subgroups. Finally, a nomogram constructed with this signature and clinicopathologic risk factors was assessed by C-index and survival calibration curves.</p><p><strong>Results: </strong>The fusion signature performed better than the radiomics signature. Then we combined this signature and 2 clinicopathologic risk factors. This nomogram showed an increase of about 20% in C-index values when compared to clinical nomogram in both datasets. Its prediction probability was also in good agreement with the actual ratio.</p><p><strong>Conclusion: </strong>The proposed fusion nomogram provided a noninvasive and easy-to-use model for survival prognosis of ccRCC patients in future clinical use, without the requirement to perform a detailed segmentation for radiologists.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"103 51","pages":"e40723"},"PeriodicalIF":1.3,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11666162/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of secukinumab in Takayasu arteritis with myocardial infarction complicated with generalized pustular psoriasis: A case report.","authors":"Tomoyuki Asano, Shuhei Yoshida, Naoki Matsuoka, Masato Ishikawa, Akihiko Sato, Shotaro Ogawa, Kenji Saito, Yuya Sumichika, Haruki Matsumoto, Jumpei Temmoku, Yuya Fujita, Shuzo Sato, Yasuchika Takeishi, Toshiyuki Yamamoto, Kiyoshi Migita","doi":"10.1097/MD.0000000000040994","DOIUrl":"10.1097/MD.0000000000040994","url":null,"abstract":"<p><strong>Rationale: </strong>Takayasu arteritis (TAK) is an autoimmune disease that causes chronic inflammation targeting the aortic wall. Since many patients are resistant to steroid treatment, multiple immunosuppressants or interleukin-6 (IL-6) suppression therapy have served as treatment alternatives. However, there are very few reports on the effectiveness of biologics against inflammatory cytokines upstream of IL-6.</p><p><strong>Patient concerns: </strong>We present a case of TAK in a 51-year-old female presenting with a myocardial infarction. She had persistent carotid wall thickening despite glucocorticoid (GC) therapy, and IL-6 suppression therapy was being proactively considered. While the GC was being tapered, widespread pustules appeared all over her body.</p><p><strong>Diagnosis: </strong>TAK complicated with generalized pustular psoriasis (GPP).</p><p><strong>Interventions: </strong>Aside from GC, the patient was treated with secukinumab (SEC), an anti-IL-17A monoclonal antibody.</p><p><strong>Outcomes: </strong>Immediately after treatment with SEC, the pustules disappeared, and the thickening of the common carotid artery wall improved on ultrasound.</p><p><strong>Lessons: </strong>Since IL-17 is an important cytokine in the pathogenesis of TAK, anti-cytokine therapy targeting IL-17 may be effective for TAK.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"103 51","pages":"e40994"},"PeriodicalIF":1.3,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11666216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of acute angle closure in patients with primary angle closure without prophylactic iridotomy during pharmacological mydriasis for cataract surgery.","authors":"Naris Kitnarong, Theerajate Phongsuphan, Tanapath Tanratanavong","doi":"10.1097/MD.0000000000041020","DOIUrl":"10.1097/MD.0000000000041020","url":null,"abstract":"<p><p>The objective was to study the incidence of acute primary angle closure (acute PAC) during pharmacologic mydriasis before cataract surgery and changes in anterior chamber angle parameters in patients with primary angle closure diseases (PACD) with and without prophylaxis laser peripheral iridotomy (LPI). This was a prospective, comparative study of cataract patients with PACD with and without prophylaxis LPI presented at the Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand during June 2022 to December 2023. The incidence of acute PAC during pharmacologic mydriasis prior to cataract surgery was recorded. Changes in anterior chamber depth (ACD) and anterior chamber angle parameters measured with anterior segment optical coherence tomography before and after cataract surgery were compared between groups using Student t test. There were 195 eyes of 116 patients with a mean age of 70 years enrolled in the study. Eighty patients were women and 36 were men. There were 99 eyes without prophylaxis LPI and 96 eyes with LPI. There was significantly more angle-closure glaucoma in the non-LPI group than in the LPI group. Preoperatively, all anterior chamber angle parameters were significantly greater in the LPI group than in the non-LPI group (P < .001 all parameters), except ACD (P = .83) and anterior chamber width (ACW) (P = .30). All participants underwent uneventful cataract surgery. Postoperatively, all parameters of the anterior chamber angle and ACD increased significantly in both groups. When comparing between groups, all postoperative anterior chamber angle parameters were not significantly different between the groups, but ACD was significantly greater (P = .036) and ACW was lower in the LPI group (P = .008). There was no incidence of acute PAC occurring during pharmacological mydriasis before cataract surgery in both groups. There was no incidence of acute PAC in patients with and without prophylaxis LPI during pharmacological mydriasis in the preoperative preparation for cataract surgery. Eyes without LPI showed significantly lower preoperative anterior chamber angle parameters compared to eyes with previous LPI, but not significantly different postoperatively. The benefits of prophylactic LPI for PACD scheduled for cataract surgery must be further investigated.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"103 51","pages":"e41020"},"PeriodicalIF":1.3,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11666148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research progress on the mechanism of hyperuricemic nephropathy based on multi-omics technique: A review.","authors":"Kaiqing Li, Xue Xia, Tong Fu, Yanchun Ma, Yingwei Wang, Mingming Fan, Songyan Wang, Guoli Xing, Ying Tong","doi":"10.1097/MD.0000000000040975","DOIUrl":"10.1097/MD.0000000000040975","url":null,"abstract":"<p><p>Hyperuricemic nephropathy is a metabolic disease in which renal uric acid deposition and excretion are impaired due to elevated levels of uric acid in the blood, leading to impaired renal tubule function and chronic renal disease. Hyperuricemic nephropathy is one of the important complications of hyperuricemia, which seriously affects the quality of life and prognosis of patients. The pathogenesis of hyperuricemic nephropathy involves a variety of factors, including: amino acid metabolism disorder, energy metabolism abnormality, increased nucleotide metabolism, lipid metabolism disorder and bile acid metabolism imbalance, REDOX process disorder, cell cycle and apoptosis imbalance, signal transduction and inflammatory response enhancement, and intestinal flora imbalance. In recent years, omics techniques such as metabolomics, transcriptomics and intestinal microecology have been used to reveal the metabolic, gene and microflora characteristics of hyperuricemic nephropathy from different levels, as well as their interactions and regulatory mechanisms. This paper reviews these studies, analyzes the existing problems and challenges, and puts forward future research directions and suggestions, aiming at providing new theoretical basis and practical guidance for the prevention and treatment of hyperuricemic nephropathy.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"103 51","pages":"e40975"},"PeriodicalIF":1.3,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11666175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk prediction models for non-invasive ventilation failure in patients with chronic obstructive pulmonary disease: A systematic review.","authors":"Yuming Gao, Bo Yuan, Peng Fan, Mingtao Li, Jiarui Chen","doi":"10.1097/MD.0000000000040588","DOIUrl":"10.1097/MD.0000000000040588","url":null,"abstract":"<p><strong>Background: </strong>Chronic obstructive pulmonary disease (COPD) is a common respiratory condition with high morbidity and mortality. Noninvasive mechanical ventilation (NIV) is often used to manage acute COPD exacerbations, but failure can lead to worse outcomes. This systematic review aimed to evaluate risk prediction models for NIV failure in patients with COPD.</p><p><strong>Methods: </strong>PubMed, Embase, Web of Science, The Cochrane Library, CINAHL, CBM, CNKI, Wanfang, and VIP databases, from database inception to January 10, 2024, were searched for studies on risk prediction models for failure in NIV among COPD patients. Two reviewers independently screened the literature, extracted data, assessed the quality of included studies using the Prediction Model Risk of Bias Assessment Tool, and conducted a systematic evaluation of the prediction models.</p><p><strong>Results: </strong>A total of 11 studies were included, encompassing 13 risk prediction models. The area under the receiver operating characteristic curve for the included models ranged from 0.810 to 0.978. Predictive factors in the models mainly included Acute Physiology And Chronic Health Evaluation II score, pH value, PaCO2, consciousness status, serum albumin level, and respiratory rate.</p><p><strong>Conclusion: </strong>Existing risk prediction models for failure in NIV among patients with COPD demonstrated overall good predictive performance, but exhibited a risk of bias. Further validation is needed to assess the clinical applicability of these models.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"103 51","pages":"e40588"},"PeriodicalIF":1.3,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11666141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent cholangitis due to an intrahepatic calculus caused by migrated coil for vascular embolization: A case report.","authors":"Naotake Funamizu, Kyosei Sogabe, Mio Uraoka, Yuki Numata, Mitsuhito Koizumi, Chihiro Ito, Yoshitomo Ueno, Yoshio Ikeda, Yuzo Umeda","doi":"10.1097/MD.0000000000041038","DOIUrl":"10.1097/MD.0000000000041038","url":null,"abstract":"<p><strong>Rationale: </strong>Pseudoaneurysm is a potential postoperative complication in hepatobiliary and pancreatic surgery, with catheter-based interventions being the first-line treatment. This study reviews the literature on potential secondary complications following arterial embolization. Additionally, we report a case in which a dislodged embolization coil acted as a nidus for bile duct stone formation, leading to recurrent cholangitis. This report aims to raise awareness among clinicians regarding such clinical scenarios.</p><p><strong>Patient concerns: </strong>In the current report, we discuss the case of a 43-year-old male patient, who had undergone coil embolization due to a hepatic artery pseudoaneurysm after biliary reconstruction because of bile duct injury during the laparoscopic cholecystectomy, was admitted to our hospital for repeated cholangitis.</p><p><strong>Diagnoses: </strong>Imaging modalities confirmed that the previously embolized coil had migrated into the bile duct, which was identified as the cause.</p><p><strong>Interventions: </strong>A double-balloon endoscopy revealed stones with a migrated coil as its nucleus.</p><p><strong>Outcomes: </strong>The endoscopic stone removal was completed.</p><p><strong>Lessons: </strong>We encountered a case in which an arterial embolization coil used for the treatment of a pseudoaneurysm migrated into the bile duct, acting as a nidus for stone formation and resulting in recurrent cholangitis. In patients with a history of intrahepatic coil embolization, it is essential to first confirm the location of the coil within the vasculature and then investigate the underlying cause of stone formation. It is important to consider coil migration as a differential diagnosis in cases of bile duct stones following hepatic artery embolization with coils.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"103 51","pages":"e41038"},"PeriodicalIF":1.3,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11666128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}