Medicine最新文献

{"title":"Serum visfatin characteristic peak screening coronary heart disease study based on Raman spectroscopy.","authors":"Lujia Yang, Chaohui Lv, Zhongwei Yang, Feng Shi, Xiayan Liu","doi":"10.1097/MD.0000000000042081","DOIUrl":"10.1097/MD.0000000000042081","url":null,"abstract":"<p><p>This study used Raman spectroscopy to explore differences between serum visfatin and its subcomponents in healthy people and coronary heart disease (CHD) patients. To explore whether serum visfatin can be used as screening biomarker for CDH. In total, 60 CHD patients and 57 healthy people were enrolled from Xinjiang Production and Construction Corps Seventh Division Hospital. Serum samples were collected and detected by Raman spectroscopy, and the characteristic peaks of serum visfatin were analyzed. The spectral peaks analysis showed, the peaks at 850.95, 1265.92, 1336.99, 1446.48, 1603.83, and 1657.69 cm-1 were stronger in the CHD patient sample, and the spectral peaks at 1000.52, 1154.51, and 1515.53 cm-1 were stronger in the healthy sample. Clinical sample verification revealed that the 1265.92 and 1446.48 cm-1 peaks had certain distinguishing effects on CHD patients and healthy people.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e42081"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crohn's disease but not ulcerative colitis elevated risk of end-stage renal disease and mortality: A Taiwan retrospective cohort study.","authors":"Ming-Che Chuang, Tzu-Ju Hsu, Fuu-Jen Tsai, Jye-Lin Hsu, Tsung-Yu Tsai","doi":"10.1097/MD.0000000000042026","DOIUrl":"10.1097/MD.0000000000042026","url":null,"abstract":"<p><p>Inflammatory bowel disease (IBD) is an autoinflammatory disease which may affect extraintestinal organs, including kidney. However, rare research showed that patients with IBD have higher risk of end-stage renal disease (ESRD). Furthermore, lack of studies compared the potential risk of ESRD and mortality among patients with ulcerative colitis (UC) and Crohn disease (CD). We conducted a nationwide cohort study using the National Health Insurance database in Taiwan, from January 2008 to December 2018. A total of 3204 patients diagnosed with IBD were enrolled. IBD cases were identified through the presence of a catastrophic illness certificate, including CD and UC. The study outcomes were the incidence of ESRD and mortality. ESRD diagnosis required a serious illness certificate and was identified using the corresponding ICD-10-CM codes. Mortality was recorded in the Taiwan Death Registry linked with the National Health Insurance database, Cox proportional hazards models were used to estimate the risk factors for ESRD and mortality among IBD patients. CD patients had a significantly higher risk of ESRD (adjust hazard ratio: 2.32, 95% confidence interval: 1.28-4.18) and mortality (adjust hazard ratio: 1.80, 95% confidence interval: 1.37-2.35) compared to healthy individuals. UC patients showed no difference in the risk of ESRD compared to healthy individuals. Instead, among IBD patients, UC poses a relatively lower risk for ESRD compared to other factors like age and other comorbidities. Elevated risk of ESRD and mortality was only noted in patients with CD but not UC. Surprisingly, UC patients had lower risk of ESRD and mortality than CD patients. These findings highlight distinctive patterns of risk associated with CD and UC, emphasizing the importance of considering disease subtype when assessing outcomes such as ESRD and mortality.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e42026"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the regional and demographic variables in alcoholic liver disease-related mortality trends in the United States from 1999 to 2020: A cross sectional study.","authors":"Malik Saad Hayat, Muhammad Mukarram Shoaib, Sara Sohail, Shahzaib Ahmed, Fatima Shahid, Hadia Ahmad, Mohammad Rayyan Naseer, Muhammad Mohtasham Shoaib, Raheel Ahmed","doi":"10.1097/MD.0000000000041988","DOIUrl":"10.1097/MD.0000000000041988","url":null,"abstract":"<p><p>Alcoholism-related liver diseases are becoming one of the leading causes of cirrhosis- related deaths in the United States. Analyzing the temporal trends in alcoholic liver disease-related mortality among individuals, identifying the populations at high risk, and guiding the implementation of tailored interventions to address the escalating effects of alcoholic liver disease (ALD) on public health. Data extracted from death certificates via the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database was examined from 1999 to 2020 for ALD related age-adjusted mortality rates (AAMRs). The data was stratified by year, age, gender, race and geographical region. Annual percentage changes were calculated using Joinpoint Regression Program. A total of 373,302 deaths occurred due to ALD from 1999 to 2020. ALD related AAMRs declined from 1999 to 2006, followed by an initial slow rise till 2018, and then rising rapidly from 2018 to 2020. Individuals aged 55 to 64 had the highest mortality rates. Males had higher AAMRs than females. American Indians or Alaskans exhibited the highest AAMRs, and Asians or Pacific Islanders had the lowest. Western America having the highest mortality rate. New Mexico had the highest AAMR among states. Rural United States was a hotspot for ALD related mortality. There is an overall increase in ALD-related deaths in the United States from 1999 to 2020. The highest AAMRs were observed in American Indians or Alaskan, males, 55 to 64 years of age, in the Western region, in New Mexico state, and rural areas.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e41988"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case report and literature review of self-improving collodion baby in the newborn.","authors":"Yanping Guo, Zhihao Xiao, Xiaoyan Hu, Ying Liu, Guobing Chen","doi":"10.1097/MD.0000000000042045","DOIUrl":"10.1097/MD.0000000000042045","url":null,"abstract":"<p><strong>Rationale: </strong>Self-improving collodion baby (SICB) is a rare subtype of autosomal recessive congenital ichthyosis with distinct clinical features and generally favorable prognosis. This study aims to enhance understanding of SICB by examining its clinical characteristics and recent developments in diagnosis and management. Our findings provide insights that may aid in the etiological diagnosis and treatment of congenital ichthyosis.</p><p><strong>Patient concerns: </strong>We present a case of SICB treated at Peking University Shenzhen Hospital, characterized by the appearance of a collodion membrane at birth. The primary approach involved intensive moisturizing care to manage skin abnormalities.</p><p><strong>Diagnoses: </strong>Based on clinical examination and genetic testing, a diagnosis of SICB was confirmed, with mutations identified in genes commonly associated with autosomal recessive congenital ichthyosis, such as ALOX12B, TGM1, ALOXE3, CYP4F22, and PNPLA1.</p><p><strong>Outcomes: </strong>The patient showed significant improvement following targeted supportive care, consistent with the generally positive prognosis for SICB.</p><p><strong>Lessons: </strong>A comprehensive literature review of 31 SICB cases from 18 studies highlighted that the condition typically presents at birth with a collodion membrane. Intensive moisturizing is the main treatment, and early genetic testing is recommended to facilitate timely diagnosis and intervention. Early diagnosis can support effective genetic counseling and improve outcomes for newborns with ichthyosis.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e42045"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acupuncture clinical hotspots and trends from 2013 to 2022: A bibliometric and visualized analysis.","authors":"Xiangdong Wang, Bo Li, Yuping Ma, Ying Cui, Xinming Yang, Yuxian Li, Anna Jing, Yutong Zhou, Mingyue Li, Sixuan Wang, Yufeng Tu","doi":"10.1097/MD.0000000000041890","DOIUrl":"10.1097/MD.0000000000041890","url":null,"abstract":"<p><p>Through bibliometric analysis, trends in international acupuncture clinical development, key research areas, and current scientific issues were identified based on literature published from 2013 to 2022. Literature on acupuncture in clinical settings was retrieved and analyzed in this study utilizing the Web of Science database. A visualization analysis of the scientific landscape was performed using CiteSpace, VOSviewer, and GraphPad Prism. General statistics regarding the literature were examined, encompassing annual publication trends, citation frequencies, journal distributions, distributions across subject fields. Co-occurrence and cluster analyses of authors, countries, institutions, high-quality literature, and keywords were performed to explore the developmental trends, hotspots, and frontiers in acupuncture research comprehensively and intuitively. A total of 4554 studies were included, with an increasing trend in the number of publications related to the annual acupuncture Scientific Citation Index (SCI). The impact factors of the top 10 journals were mostly 1 to 3 points. The 10 most cited articles primarily concentrated on the use of acupuncture for pain-related disorders. Acupuncture and electroacupuncture are the dominant keywords, with terms such as \"ischemic stroke\" and \"Alzheimer's disease\" emerging from 2019 to 2022. From 2013 to 2022, the output of clinical SCI literature on acupuncture increased, acupuncture research gradually gained international recognition, and China gradually moved toward a dominant position. The most significant clinical research area of acupuncture is its application for analgesia, particularly through acupuncture and electroacupuncture. Future research directions may include the treatment of knee osteoarthritis, cognitive disorders, and assisted reproduction utilizing acupuncture.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e41890"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Appendicitis with perforation caused by metal dental graft: A case report.","authors":"Yinmin Sun, Shiqi Liu, Yufeng Li, Dongwen Quan, Siqi Li","doi":"10.1097/MD.0000000000042056","DOIUrl":"10.1097/MD.0000000000042056","url":null,"abstract":"<p><strong>Rationale: </strong>Under normal circumstances, foreign objects in the digestive tract can be expelled naturally through the anus via the digestive tract's peristalsis mechanism. In clinical practice, foreign bodies ingested orally seldom pass through the cecum into the appendiceal lumen, potentially leading to secondary appendicitis or even perforation - a highly infrequent but severe complication. This article aims to share our experience and insights in managing such rare cases, exploring diagnostic pathways and treatment options, and serving as a reference for colleagues.</p><p><strong>Patient concerns: </strong>A 57-year-old male patient may have accidentally ingested a tooth graft, resulting in right lower quadrat pain. Based on the physical examination and imaging findings, the likelihood of AA with perforation is high.</p><p><strong>Diagnoses: </strong>Acute appendicitis (AA) with perforation.</p><p><strong>Interventions: </strong>Laparoscopic appendectomy (LA) and removal of foreign bodies.</p><p><strong>Outcomes: </strong>After surgical treatment, the patient recovered well, and there were no recent complications such as wound infection, incisional hernia, and massive hemorrhage.</p><p><strong>Lessons: </strong>In the diagnosis of appendicitis caused by foreign bodies, clinical history, physical examination, and imaging are crucial to the diagnosis of the disease. Once diagnosed, surgery should be taken quickly. LA offers several advantages, including minimal trauma, excellent visualization, precise treatment outcomes, and swift patient recovery. Therefore, we recommend it as the preferred treatment for appendiceal perforation caused by foreign bodies.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e42056"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical analysis of 7 cases of cryptogenic new-onset refractory status epilepticus.","authors":"Haiyan Diao, Haixia Qu, Yanhong Wang","doi":"10.1097/MD.0000000000039214","DOIUrl":"10.1097/MD.0000000000039214","url":null,"abstract":"<p><p>There are relatively few studies related to new-onset refractory status epilepticus (NORSE), in which patients with cryptogenic NORSE have more frequent and longer duration seizures than patients with a clear etiology, are more likely to develop drug-refractory epilepsy and have a more likely prognosis of severe cognitive impairment. We conducted a series of case studies to investigate the treatment options and prognosis of NORSE. Seven adult patients with cryptogenic NORSE treated at the Third Hospital of Shanxi Medical University between June 2016 and April 2022 were reviewed. We collected basic information and clinical data of the study subjects, including demographic characteristics, clinical manifestations, laboratory test and imaging data, medication use, and prognostic regression, using a modified Rankin Scale score (MRS). The median age of the 7 patients with cryptogenic NORSE was 32 years (interquartile range 25.00-39.00), and 4 patients (57.1%) were male. Six patients (85.7%) had a history of prodromal fever; 2 (28.6%) patients received high-dose propofol and midazolam and 5 (71.4%) patients received high-dose phenobarbital, of which 4 patients (57.1%) were treated with a ketogenic diet KD. The overall mortality rate was 28.6% (2/7), and 2 patients died during hospitalization (both treated with high-dose propofol and midazolam). Of all surviving patients at discharge, 3 patients (60%) had an mRS score of 2 and 2 patients (40%) had an mRS score of 4. In the 3-month post-discharge follow-up data, all surviving patients had an mRS score of 2. In a retrospective study of our cohort high-dose phenobarbital combined with a ketogenic diet may be safe and effective in the treatment of cryptogenic NORSE.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e39214"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Compliance of infection control practices among registered nurses: A cross-sectional study.","authors":"Suzan Harb, Ghada Abu Shosha, Islam Ali Oweidat, Khalid Al-Mugheed, Majdi M Alzoubi, Sally Mohammed Farghaly Abdelaliem","doi":"10.1097/MD.0000000000042062","DOIUrl":"10.1097/MD.0000000000042062","url":null,"abstract":"<p><p>Nurses are essential in the upkeep, maintenance, and implementation of infection control standards and guidelines by ensuring that their practices reflect the current evidence in the prevention of infectious diseases. The study performed to measure the level of infection control practices compliance among nurses. A cross-sectional design, was performed among nurses in 3 governmental hospitals. Infection control practices Tool were shared between August 2023 and October 2023, made up of 29 questions scored using a 5-point Likert scale. Overall mean levels of infection control practices were rated weak compliance (raw score = 105, mean = 3.64, standard deviation [SD] = 0.9). The items with the highest rated scores were Item 1 (\"I wash my hands before and after giving care to patient\") (raw score = 110, mean = 3.79, SD = 1.0) and Item 25 (\"I inform other units before transferring patients who are under contact precautions\") (raw score = 110, mean = 3.79, SD = 1.1). None of the sociodemographic variables analyzed show a statistically significant relationship with infection control practices, as all P-values are >.05. Nurse, managers, and hospital administrators should ensure that policies reflect the critical significance of infection control practices in preventing further morbidity and mortality among hospitalized patients and protecting the health and well-being of nurses and other healthcare staff.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 14","pages":"e42062"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge of and acceptability towards human papilloma virus vaccine in Saudi Arabia: A cross-sectional survey study.","authors":"Mohammed Samannodi, Shahad Mohammed Mousa, Lama Adnan Mandourah, Shayma Saleh Al-Rubaki, Maram Sulaiman Gubari, Wala Salem Fallatah, Sarah Tayeb, Mohammed A Almatrafi, Mohammed Shaikhomer, Hassan Alwafi, Ahmad A Imam, Enad Alsolami","doi":"10.1097/MD.0000000000041941","DOIUrl":"10.1097/MD.0000000000041941","url":null,"abstract":"<p><p>Vaccination against human papilloma virus (HPV) play a major role in preventing infection with HPV among heterosexual couples. The aim of this study was to assess public knowledge and attitude towards HPV vaccine in Saudi Arabia. This is an online cross-sectional survey study that was conducted between May and June 2023. This study utilized the convenience sampling technique to recruit the study participants. The study participants were invited to participate in this study through social media platforms (X, Facebook, and WhatsApp). Multiple logistic regression was performed to assess the factors associated with better knowledge level and the findings were presented as odds ratios (OR) with 95% confidence intervals (CI) and corresponding p-values. A total of 819 participants were included in the analysis. A total of 355 participants (43.3%) had a good knowledge score and 464 participants (56.7%) had poor knowledge. The total mean of knowledge score was (3.22 ± 2.44). As the table shown, single participants reported a significant higher knowledge score mean (3.59 ± 2.52) compared to married (2.84 ± 2.32) (P = .0001). Participants aged between 18 to 29 years reported a significant higher knowledge score mean (3.57 ± 2.52) compared to participants aged between 40 and 49 years (2.60 ± 2.21) (P = .0001). Participants who lived in Eastern area had significantly higher odds of knowledge compared to other areas (OR = 2.19, 95% CI = 1.45 - 3.33, P = .001). Participants who worked in medical field had significantly higher odds of having good knowledge compared to other jobs (OR = 3.65, 95% CI = 2.39-5.57, P = .0001). Participants who had 2 sexual partners have you had in the past 2 years had a significant higher odd of having good knowledge (OR = 2.05, 95% CI = 1.02-4.12, P = .04). This study identified that a considerable proportion of the study participants demonstrated poor level of knowledge of HPV vaccine. Participants who lived in Eastern area, those who worked in medical field, and those who had 2 sexual partners have you had in the past 2 years had a significant higher odd of having good knowledge. Future studies should be directed towards developing educational campaign to improve public awareness of HPV.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 13","pages":"e41941"},"PeriodicalIF":1.3,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11957628/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143736051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subcutaneous acupuncture improves acyclovir-ineffective cephalofacial herpes zoster: A case report.","authors":"Zhenzhen Wang, Zhenming Zeng, Xiahai Zheng, Haiwei Gao, Haoxiong Chen, Yujia Chen","doi":"10.1097/MD.0000000000042066","DOIUrl":"10.1097/MD.0000000000042066","url":null,"abstract":"<p><strong>Rationale: </strong>Herpes zoster is a common skin disease that manifests as clustered herpes, postherpetic neuralgia (PHN), and other herpes zoster-related complications, as well as eye diseases and various visceral diseases. Pharmaceutical therapy may cause adverse responses and has limited efficacy. Therefore, exploring alternative and effective therapies is important for clinical physicians.</p><p><strong>Patient concerns: </strong>The patient was a 62-year-old female. She suffered from clustered herpes in her left forehead and head, which caused severe pain. The patient had received pharmaceutical therapy but did not respond to it.</p><p><strong>Diagnoses: </strong>Cephalofacial herpes zoster.</p><p><strong>Interventions: </strong>The patient underwent a 1-week course (4 sessions) of subcutaneous acupuncture. The treatment involved fire acupuncture (swift pricking) and common acupuncture (transverse insertion), both of which were performed on the superficial skin layer.</p><p><strong>Outcomes: </strong>After the 4 treatment sessions, the patient's herpes disappeared quickly, and the pain was relieved. After the 12-month follow-up, the patient had no PHN.</p><p><strong>Lessons: </strong>Subcutaneous acupuncture improved the skin lesions condition of herpes zoster rapidly, and relieved the neuralgia effectively. It may prevent the PHN. For patients who are nonresponsive to antiviral medications, especially the elderly population at a high risk of developing PHN, subcutaneous acupuncture (fire acupuncture + common acupuncture) can be considered.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 13","pages":"e42066"},"PeriodicalIF":1.3,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11957639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143736102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}