Medical Journal of the Islamic Republic of Iran最新文献

{"title":"Sonographic Evaluation of the Superficial Back Line Myofascial Release in Plantar Fasciitis: A Single-Blind Randomized Controlled Trial.","authors":"Seyed Mehdi Mohsenipour, Ali Amiri, Javad Sarrafzadeh, Farid Bahrpeyma","doi":"10.47176/mjiri.39.60","DOIUrl":"10.47176/mjiri.39.60","url":null,"abstract":"<p><strong>Background: </strong>Myofascial tissues are interconnected, and fascia connects them to forming a web of myofascial chains. This research investigated whether incorporating myofascial release along the superficial backline offers additional benefits compared to a localized gastrocnemius release in managing clinical symptoms and plantar fascia thickness in individuals with chronic plantar fasciitis.</p><p><strong>Methods: </strong>This was an add-on design a single-blind randomized clinical trial that was conducted with 30 chronic plantar fasciitis patients. Subjects were randomized into two groups: the Gastrocnemius Myofascial Release (G-MFR) group and the Chain Myofascial Release (C-MFR) group. Each participant underwent four MFR sessions over two weeks. Outcome measures included the Numeric Pain Rating Scale (NPRS), the Foot Function Index (FFI), and ultrasound-based evaluations of plantar fascia thickness. Due to the non-normal distribution of change scores, between-group comparisons were performed using the Mann-Whitney test with the Hodges-Lehmann estimator, and effect sizes were reported using r values.</p><p><strong>Results: </strong>Both groups exhibited significant improvements in NPRS and FFI scores post-intervention (<i>P</i><0.001), with the C-MFR group showing greater reductions in both measures (for NPRS: <i>P</i>=0.004, r=0.686 and for FFI: <i>P</i>=0.004, r=0.518). However, while plantar fascia thickness decreased significantly in the C-MFR group (<i>P</i>=0.001, r=0.829), no significant change was observed in the G-MFR group (<i>P</i>=0.422, r=0.206). The reduction in thickness for C-MFR compared to G-MFR was not statistically significant (<i>P</i>=0.233, r=0.222).</p><p><strong>Conclusion: </strong>This study suggests that myofascial release in the superficial backline chain is more effective than isolated gastrocnemius release for improving NPRS and FFI scores in chronic plantar fasciitis. Future studies with longer follow-ups may clarify the long-term effects of these interventions on plantar fascia thickness.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"60"},"PeriodicalIF":0.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study of the Effectiveness of Apoptosis Biomarkers in the Diagnosis of Gastric Cancer in Kazakhstan: A Review of Systematic Evidence.","authors":"Anar Tulyayeva, Yerbolat Iztleuov, Nurgul Kereyeva, Marzhan Aitmagambetova, Saule Akhmetova","doi":"10.47176/mjiri.39.59","DOIUrl":"10.47176/mjiri.39.59","url":null,"abstract":"<p><strong>Background: </strong>Gastric cancer in Kazakhstan shows low survival rates due to late diagnosis. This study aimed to explore apoptosis biomarkers to improve early detection and diagnostic accuracy. By investigating biomarkers like p53, RAS, miRNAs, and inflammation markers, the study sought to identify potential indicators for better prognosis and survival outcomes.</p><p><strong>Methods: </strong>This systematic review was conducted using the keywords \"apoptosis biomarkers\" OR \"gastric cancer\" AND \"Kazakhstan\" OR \"Kazakhstani\" in the PubMed and Google Scholar databases, yielding 2,025 records. After filtering, 24 studies were selected for analysis. Quality was assessed using the Newcastle-Ottawa Scale, and data were extracted and synthesized for critical findings.</p><p><strong>Results: </strong>This systematic review on apoptosis biomarkers in gastric cancer diagnosis in Kazakhstan highlights key findings across diverse studies. Biomarkers with the strongest diagnostic potential include p53, RAS, miRNAs (e.g., miR-21, miR-34a), and inflammation markers like NLR (neutrophil-to-lymphocyte ratio), PLR (platelet-to-lymphocyte ratio), and SII (systemic immune-inflammation index). Cytokines, including IL-2 and TNF, were linked to prognosis. DNA repair markers such as γ-H2AX and 53BP1 correlated with improved survival rates. Male predominance was consistent, with 63.1% to 66.4% of participants being male. Key environmental risk factors include Helicobacter pylori infection and heavy metal contamination. Survival rates ranged from 7.3% (Stage IV) to 50.5% (Stage I). The study also observed a statistically significant reduction in mortality rates from 14.0 to 8.9 per 100,000 (p<0.001), reflecting improvements in cancer management and diagnostic interventions.</p><p><strong>Conclusion: </strong>This review underscores the pivotal role of apoptosis biomarkers in gastric cancer diagnosis in Kazakhstan. Biomarkers such as p53, RAS, and inflammation indices are integral to prognosis. Personalized diagnostic approaches, early detection, and targeted treatments can significantly improve survival outcomes and cancer management in this population.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"59"},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Efficacy of Topical <i>Arnebia euchroma</i> Product with Topical Phenytoin on Pressure Ulcer in Patients with Spinal Cord Injury: A Triple-Blind, Randomized Clinical Trial.","authors":"Sakineh Erabi, Ali Ghobadi, Fataneh Hashem-Dabaghian, Mostafa Dahmardehei, Hoorieh Mohammadi Kenari","doi":"10.47176/mjiri.39.58","DOIUrl":"10.47176/mjiri.39.58","url":null,"abstract":"<p><strong>Background: </strong><i>Arnebia euchroma (Ae)</i> in traditional Persian medicine is used for wound treatment. This study assessed the efficacy of <i>Ae</i> liniment on pressure ulcer (PU) remedy in patients with Spinal Cord Injury.</p><p><strong>Methods: </strong>In this triple-blind, randomized clinical trial, grade 2 and 3 wounds were randomly assigned to receive either <i>Ae</i> liniment or Phenytoin Cream 1% twice a day for 5 weeks. Recovery was measured by the wound size, exudate, and tissue type by the \"Pressure Ulcer Scale for Healing\" (PUSH) tool on days 0, 7, 14, 21, 28, and 35. PUSH score between groups was compared with the Mann-Whitney U test, and also within each group by Friedman test.</p><p><strong>Results: </strong>74 patients (37 in each group) participated and completed the study. Mean±SD of PUSH Scores at baseline, and 1,2,3,4,5 week after the treatment in <i>Ae</i> group were 9.73±2.65, 9.92±3.08, 8.24±3.86, 7±4.08, 5.22±4.3, 3.41±3.85 and in Phenytoin group were 10.05±1.85, 9.97±1.9, 9.59±2.08, 9.22±2.09, 8.54±2.72, 7.57±3.26. PUSH Score decrease in the <i>Ae</i> group was70.33 ± 32.25% , and in group 2 was 27.67± 26.8% (<i>P</i> < 0.001), which indicates that in comparison of the PUSH Score decrease between the two groups, this reduction was significantly higher in the <i>Ae</i> group. During the study, complete wound healing was observed in 16 patients (43.2%) in the <i>Ae</i> group and in the Phenytoin group in 3 wounds (8.1%) (<i>P</i> = 0.010). No side effects were reported in either group.</p><p><strong>Conclusion: </strong>PU healing was significantly better in the <i>Ae</i> group than phenytoin cream. It may be considered as a potential option in the treatment of PU in patients with Spinal Cord Injury.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"58"},"PeriodicalIF":0.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Assessment of the Diagnostic Accuracy of Magnetic Resonance Diffusion Kurtosis Imaging in Diagnosing Degenerative Lumbar Spine Disease: A Scoping Review.","authors":"Neil Abraham Barnes, Winniecia Dkhar, Rajagopal Kadavigere, Abhimanyu Pradhan","doi":"10.47176/mjiri.39.57","DOIUrl":"10.47176/mjiri.39.57","url":null,"abstract":"<p><strong>Background: </strong>Degenerative disorders of the lumbar spine are a common cause of chronic pain and disability, particularly in older adults. They involve the progressive degeneration of intervertebral discs, which leads to symptoms such as lower back pain, nerve compression, and neurological deficits. While traditional MRIs are a widely used and effective tool for diagnosing many spinal conditions, including degenerative disorders of the lumbar spine, they do have limitations when it comes to detecting early microstructural changes in the intervertebral discs and other spinal components. This limitation can delay diagnosis and intervention in the early stages of degeneration, which is critical for preventing progression. The scoping review aims to sensitize the current evidence on the diagnostic performance of Diffusion Kurtosis Imaging (DKI) in detecting and characterizing degenerative changes in the lumbar spine.</p><p><strong>Methods: </strong>Using the Arksey and O'Malley framework, we performed an extensive literature search across Scopus, Embase, and PubMed to identify relevant studies published between January 2010 and 2024. The selection criteria included 3T MRI studies utilizing DKI techniques aimed at evaluating degenerative changes in the lumbar spine.</p><p><strong>Results: </strong>The total number of studies included in this study was 3 out of 355, where our preliminary findings indicate that the DKI parameters demonstrated an early detection of microstructural changes within the degenerative lumbar spine as compared to the healthy controls. Accordingly, these changes are highly correlated with clinical symptoms and the extent of degeneration observed on conventional MRI, suggesting that DKI is more sensitive to detecting early microstructural changes.</p><p><strong>Conclusion: </strong>MR Diffusion Kurtosis Imaging offers a substantial potential for detecting subtle microstructural changes in the lumbar spine degeneration at an early stage, that is crucial for earlier diagnosis and intervention. The integration of DKI sequence into clinical practice could result in an increase in diagnostic accuracy and patient outcomes.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"57"},"PeriodicalIF":0.0,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Dental Caries and Associated Factors in 3-Year-Old Iranian Children: An Application of Random Forest for Zero-Inflated Poisson Process.","authors":"Fatemeh Masaebi, Masoud Salehi, Zahra Ghorbani, Mehdi Azizmohammad Looha, Morteza Mohammadzadeh, Marzie Deghatipour, Denis Larocque, Farid Zayeri","doi":"10.47176/mjiri.39.56","DOIUrl":"10.47176/mjiri.39.56","url":null,"abstract":"<p><strong>Background: </strong>Dental caries, caused by bacterial activity leading to tooth decay, has a profound impact on children's quality of life. This study aimed to investigate factors associated with dental caries in 3-year-old Iranian children.</p><p><strong>Methods: </strong>A cross-sectional study was conducted involving 815 three-year-old children who were referred to healthcare centers in the southern region of Tehran Province, Iran. Truncated random forest, traditional random forest, and a log-linear model were employed, utilizing the number of dental caries (including excess zeros) as the outcome variable. Predictors included sex, tooth brushing, dental flossing, sweet consumption, dental visits, and parental education level.</p><p><strong>Results: </strong>The log-linear model's rate ratio (RR) indicated that boys were more likely to have at least 1 decayed tooth compared to girls (RR, 1.11). Dental floss usage significantly reduced childhood dental caries (RR, 2.74). Variable importance analysis from 2 random forests identified dental floss usage, dental visits, and the father's educational level as the most impactful factors on childhood caries. Results based on mean squared error (MSE) demonstrated that the truncated random forest (MSE, 0.002) outperformed the log-linear model (MSE, 0.959) and exhibited similar performance to the traditional random forest model (MSE, 0.006).</p><p><strong>Conclusion: </strong>The truncated random forest model demonstrated superior performance compared to traditional random forest and log-linear models. From a clinical perspective, promoting knowledge and practices related to good oral health habits in parents and their children emerges as a crucial strategy for reducing the risk of childhood caries.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"56"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors for Surgical Site Infections in Elective and Emergency Surgeries: A Prospective Cohort Study.","authors":"Hazem A Megahed, Ahmed Taki-Eldin, Abdel-Monem A Mohamed, Masoud Kh El-Syed Ibrahim, Ashraf Ali Abdel Aziz, Hatem A Megahed, Mohamed Zeen Zeen Farg, Ahmed M Kandel, Abdorabih Alemam, Khaled Mohamed Salamh, Lamiaa Z Elmoursi, Ahmed Yousef, Mona F El Wakel","doi":"10.47176/mjiri.39.55","DOIUrl":"10.47176/mjiri.39.55","url":null,"abstract":"<p><strong>Background: </strong>Surgical site infections (SSIs) cause morbidity, disabilities, and healthcare costs. This study aims to assess patient- and surgery-related factors influencing SSIs with standardized preoperative, operative, and postoperative care.</p><p><strong>Methods: </strong>This prospective cohort study involved 140 patients undergoing elective or emergency surgeries at Al-Azhar University Hospitals, Egypt, from October 2020 to September 2021. Patients were stratified into two groups: emergency (Group A) and elective (Group B). Risk factors for SSIs were assessed through observational and analytical methods, focusing on adults aged 15 and older without prior infections. The chi-square test was utilized to assess the strength of associations for categorical variables. Statistical significance was determined at a p-value under 0.05, with a 95% confidence interval employed for all analyses. Data were tabulated using a spreadsheet and analyzed with IBM SPSS Statistics for Windows, Version 20.</p><p><strong>Results: </strong>Among 140 patients, 25 developed SSIs (19 men, 6 women). Significant differences were found in wound type (<i>P</i> = 0.001, surgery type (<i>P</i> = 0.002), and operative time (<i>P</i> = 0.010). SSI risk was higher for dirty (45.8%), contaminated (31.3%), and clean-contaminated (12.9%) wounds. Prolonged operative times (≥60 minutes) increased SSI risk (57.9% vs. 40.6%, <i>P</i> = 0.010). Diabetic patients had a higher incidence. In emergency surgeries, E. coli, Staphylococcus aureus, and Pseudomonas aeruginosa predominated, while S. aureus and Citrobacter were more common in elective surgeries. Amikacin, metronidazole, azithromycin, and imipenem were effective antibiotics.</p><p><strong>Conclusion: </strong>SSIs were more common in emergency surgeries. Risk factors included smoking, diabetes, wound contamination, and prolonged operative times. Effective antibiotic use and infection control measures can decrease SSI occurrence.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"55"},"PeriodicalIF":0.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tele-practice Versus In-Person Voice Therapy: Impacts on Vocal Characteristics of Voice Actors.","authors":"Sadaf Salehi, Leila Ghelichi, Maryam Tarameshlu","doi":"10.47176/mjiri.39.54","DOIUrl":"10.47176/mjiri.39.54","url":null,"abstract":"<p><strong>Background: </strong>Voice actors are a group of professional voice users who have heavy vocal demands in their profession and, as a result, experience a high percentage of vocal complaints. This study aimed to assess the impact of tele-practice compared to in-person voice therapy on various voice characteristics in voice actors.</p><p><strong>Methods: </strong>A pilot clinical trial was carried out on 14 voice actors and actresses who were allocated to two groups. All participants received the same voice therapy interventions for 60 minutes per session, three sessions per week for 6 weeks. Sessions for one group were held in person, while the other group received therapy remotely. The acoustic measurements, aerodynamic measurements, auditory-perceptual judgment, and self-perceived measurements as outcome measures were assessed before treatment, post-treatment, and four weeks after the end of the treatment for each group. Repeated measure ANOVA was applied to within-groups comparisons, and the Kruskal-Wallis test was used to between-group comparisons.</p><p><strong>Results: </strong>Shimmer, MPT, CAPE-V scores, VTD scores, and VHI scores improved significantly post-treatment and showed sustained improvement over time in both groups. Fundamental frequency, jitter, harmonic-to-noise ratio, and /s/ to /z/ ratio did not change significantly after treatment in both groups. None of the outcome measures had significant differences between groups in any assessment points. The power of the study was 80%.</p><p><strong>Conclusion: </strong>Tele-practice can have the same effects as in-person voice therapy. In addition, providing vocal hygiene counseling alongside continuous warm-up and cool-down exercises, breathing exercises, and head and neck exercises can lead to improved voice condition and reduced voice complaints.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"54"},"PeriodicalIF":0.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Universal Health Coverage in Iran: The Way Forward.","authors":"Mohsen Asadi-Lari, Syed Jaffar Hussain, Elham Ahmadnezhad, Zhaleh Abdi","doi":"10.47176/mjiri.39.53","DOIUrl":"10.47176/mjiri.39.53","url":null,"abstract":"","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"53"},"PeriodicalIF":0.0,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Influencing Women's Cancer Screening Behavior: A Case Study in South Eastern Iran.","authors":"Naeemeh Shahdadi, Nouzar Nakhaei, AliAkbar Haghdoost","doi":"10.47176/mjiri.39.52","DOIUrl":"10.47176/mjiri.39.52","url":null,"abstract":"<p><strong>Background: </strong>Southeast areas of Iran, particularly Kerman province, are among the deprived areas of the country which have received less attention in research about cancer screening. This study focused on screening behaviors in a relatively deprived population of Jiroft and Rabor districts of Kerman province to determine the effective factors in women's common cancers screening.</p><p><strong>Methods: </strong>In this cross-sectional study, we interviewed 970 women aged 20 to 69 years from urban and rural areas of two counties of Kerman province in Iran (Jiroft and Rabor counties), proportional to their population sizes. Participants were asked about their cancer screening history, knowledge, and attitude toward common cancers, as well as their health literacy, all measured on a scale from 0 to 100. Independent samples t-tests, ANOVA, and Pearson's correlation coefficient were utilized to examine the relationships between variables. Subsequently, a bivariate and multivariate linear regression model was used to investigate the relationship between the screening score and the other variables with 95% confidence intervals.</p><p><strong>Results: </strong>The scores for screening, knowledge, and attitude were 14.6, 58.1, and 54, respectively, while health literacy was 18.6. The correlation coefficients between screening and health literacy, awareness, attitude, and knowledge ranged from 0.2 to 0.33. Screening history was lower among older women, those with less education, housekeepers, and divorced women. There was a significant relationship between knowledge about risk factors, attitude, and health literacy.</p><p><strong>Conclusion: </strong>Although studied women had relatively acceptable scores in knowledge and attitude, cancer screening rates were relatively low. This suggests that a comprehensive approach to health promotion, beyond just health education, is needed to improve cancer screening practices among women in studied areas.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"52"},"PeriodicalIF":0.0,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual Mobility Acetabular Cup Utilization in Total Hip Arthroplasty: Mitigating Instability Risks.","authors":"Javad Khaje Mozafari, Amir Aminian, Ali Yeganeh, Mansour Abolghasemian","doi":"10.47176/mjiri.39.51","DOIUrl":"10.47176/mjiri.39.51","url":null,"abstract":"<p><strong>Background: </strong>With the increase in life expectancy and the rising number of total hip arthroplasty (THA) cases, the rate of complications is also expected to increase. One of the most challenging complications is dislocation, which is the leading cause of revision surgery within the first year after THA. This study aimed to assess hip instability rates in high-risk patients who underwent dual mobility cup (DMC) implantation.</p><p><strong>Methods: </strong>This retrospective study reviewed all patients who underwent THA with DMC at Rasul-e-Akram Hospital between 2014 and 2021. DMC was used in high-risk patients for dislocation, including those with neuromuscular diseases (e.g., Parkinson's disease, poliomyelitis) and intracapsular femoral neck fractures (FNF), instead of the standard cup. Clinical outcomes, instability, and other complications were recorded. All data was analyzed using SPSS software version 27.0.1. The chi-squared test was used to compare binary variables, and the student's t-test was used to compare numerical variables after checking for normal distribution.</p><p><strong>Results: </strong>A total of 163 patients (168 hips) underwent THA with DMC, with a mean age of 58 ± 5.3 years. Five patients had bilateral total hip surgery. The average follow-up time was 48 ± 5.8 months. The average BMI of patients was 28.3 ± 3.1. The preoperative Harris Hip Score (HHS) was 49 ± 8.5, while the postoperative HHS at the four-year follow-up was 89 ± 2.4. None of the patients experienced a dislocation requiring revision, and One case of severe wear on the polyethylene's inner surface and intraprosthetic dislocation, without a dislocated metal head, was identified and revised. No cases of component loosening or significant osteolysis were observed.</p><p><strong>Conclusion: </strong>The use of DMC can significantly reduce the dislocation rate in patients with risk factors such as femoral neck fractures while improving patient satisfaction and restoring near-normal function. We recommend greater consideration of this cup in patients at risk of dislocation.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"51"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12313306/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}