Medical Journal of the Islamic Republic of Iran最新文献

{"title":"The Effects of Manual Therapy with TECAR Therapy, on Pain, Disability and Range of Motion in Women with Non-specific Chronic Neck Pain.","authors":"Atena Bameri, Marzieh Yassin, Reza Salehi, Soheil Mansour Sohani","doi":"10.47176/mjiri.38.107","DOIUrl":"https://doi.org/10.47176/mjiri.38.107","url":null,"abstract":"<p><strong>Background: </strong>This study was designed to compare the effectiveness of manual therapy alone and a combination of it and TECAR (Transfer Energy Capacitive and Resistive) therapies on the conditions of pain, disability, and neck range of motion (ROM) in patients with non-specific chronic neck pain (NCNP).</p><p><strong>Methods: </strong>In this Randomized controlled study, 30 women with non-specific chronic neck pain were randomly divided into two groups: Manual therapy along with TECAR therapy (intervention group) and single manual therapy (control group). The participants were homogenized in terms of age, height, and weight. Both groups received manual therapy for two weeks and a total of 8 sessions. Furthermore, self-stretching the scalene muscles, upper trapezius, and suboccipital muscles was taught to the participants. After the treatment ended, patients were followed up for two weeks. The primary outcomes in this study were pain and disability. The pain was measured with the VAS index, and disability was measured with two questionnaires, namely the neck disability index (NDI) and neck pain disability scale (NPDS). The secondary outcomes in this study were neck flexion and extension AROM measured with a goniometer. Pain was evaluated in four stages, including before the treatment onset, at the end of session 4, at the end of treatment and after a two-week follow-up, and other conditions were measured in three stages including before the treatment onset, at the end of treatment and after a two-week follow-up. The Repeated Measure ANOVA (2*3), the Wilcoxon test, and the Paired Student's t-test were used. The significance level was set at <i>P</i> ˂ 0.05.</p><p><strong>Results: </strong>The comparison of the two groups indicated that at the end of the treatment period and after the follow-up, the average pain level in the intervention group was lower than that of the control group. The effect size also revealed that the combination of manual and TECAR therapies acts effectively in pain reduction. Furthermore, the combinatorial treatment compared to the single manual therapy was preferable to improving the disability, while after the two-week follow-up period, no statistically significant difference was observed between the two groups. The comparison of neck flexion and extension AROM did not reveal any difference between the two groups. The intragroup comparison also revealed that both the control and intervention groups experienced a significant decrease in pain intensity and disability level and a significant increase in neck flexion and extension AROM after the end of treatment and after a two-week follow-up compared to before the treatment (<i>P</i>> 0.05).</p><p><strong>Conclusion: </strong>Based on the results of this study, TECAR seems to be able to increase the effectiveness of manual treatments as a thermal modality.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"38 ","pages":"107"},"PeriodicalIF":0.0,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11707712/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142951223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost Effectiveness Analysis Rivaroxaban Plus Aspirin versus Aspirin alone in Treatment Cardiovascular Diseases: A Systematic Review.","authors":"Asma Rashki Kemmak, Leila Etemad, Atoosa Haghighizadeh, Nadia Saniee, Omid Rajabi","doi":"10.47176/mjiri.38.106","DOIUrl":"https://doi.org/10.47176/mjiri.38.106","url":null,"abstract":"<p><strong>Background: </strong>Cardiovascular diseases (CVDs) are one of the chronic diseases and the leading cause of death worldwide. More people die from CVDs worldwide than from any other cause each year. The effects of CVDs are not limited to mortality and morbidity but also have important health and economic outcomes.</p><p><strong>Methods: </strong>This was a systematic review that evaluated the economic evaluation of rivaroxaban plus aspirin compared with aspirin alone for the treatment of CVDs. The present study reviewed articles that performed a complete economic evaluation, including cost-effectiveness analysis, cost-utility analysis, and cost-benefit analysis related to the economic evaluation of rivaroxaban compared to enoxaparin for knee replacement patients during the years 2007 and 2023. In order to find relevant studies, databases including Pubmed, Web of Science, Embase, Scopus, Economic Evaluations Database, and Proquest were searched. Inclusion criteria included Studies that carried out a complete economic evaluation including cost-effectiveness analysis, cost-utility analysis, and cost-benefit analysis in relation to the economic evaluation of rivaroxaban plus aspirin compared to aspirin alone for CVD patients, economic evaluation studies carried out using decision analysis models based on the economic evaluation approach, full-text studies, English studies, and were studies published between 2007 and 2023. Exclusion criteria also included partial economic evaluation (such as effectiveness evaluation, cost evaluation, and quality of life evaluation), studies of low methodological quality based on the CHEERS checklist, non-English studies and all protocols, conference abstracts, and letters-to-the-editor.</p><p><strong>Results: </strong>After searching various databases, all retrieved articles were entered into EndNote software, and duplicates were removed. The remaining studies were reviewed independently by two relevant researchers. At this stage, preferred reporting items for systematic reviews (PRISMA) were used to retrieve the final articles. Out of 1048 studies, nine studies met the inclusion criteria. The economic evaluation studies included in the present study were conducted between 2018 and 2023. Cost-effectiveness analysis (CEA) was used in all studies.</p><p><strong>Conclusion: </strong>The findings of the present study showed that rivaroxaban plus aspirin is more cost-effective than aspirin alone in the patient with CVDs, But to generalize the results to other countries of the world, more studies are needed.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"38 ","pages":"106"},"PeriodicalIF":0.0,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11707709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Empagliflozin on Inflammatory Markers in Adults with Type 2 Diabetes: A Retrospective Cohort.","authors":"Hossein Samadanifard, Zahra Barati, Amir Hossein Ghanooni, Delaram Eskandari, Amir Ziaee, Haleh Chehrehgosha, Fatemeh Sarv, Shadi Zahraei","doi":"10.47176/mjiri.38.x","DOIUrl":"https://doi.org/10.47176/mjiri.38.x","url":null,"abstract":"<p><strong>Background: </strong>Inflammation plays a significant role in the development and progression of type 2 diabetes (T2D). Empagliflozin, an SGLT2 inhibitor, has shown some anti-inflammatory effects in patients with T2D. This study aimed to evaluate the impact of empagliflozin on some inflammatory markers in T2D.</p><p><strong>Methods: </strong>This retrospective single-arm cohort study included 40 patients with T2D who were treated with empagliflozin. Inflammatory markers such as serum level of erythrocyte sedimentation rate (ESR), high-sensitivity C-reactive protein (hs-CRP), neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and serum albumin were evaluated at baseline and 12 weeks after empagliflozin treatment. Statistical analysis used paired samples t test, and the statistically significant level was considered <i>P</i> < 0.05.</p><p><strong>Results: </strong>After 12 weeks, a significant reduction was found in ESR (17.75 ± 15.7 mm/hr to 14.72 ± 10.93 mm/hr; <i>P</i> = 0.025). However, the decrease in hs-CRP did not reach significance (<i>P</i> = 0.936). NLR did not show a significant reduction (<i>P</i> = 0.962), but there was a trend toward a significant decrease in PLR (107 ± 33 to 100 ± 35; <i>P</i> = 0.053). The neutrophil count did not change significantly (<i>P</i> = 0.247), but the lymphocyte count significantly increased (2.43 ± 7.85 to 2.57 ± 7.45 109/l; <i>P</i> = 0.014). Serum albumin showed a significant increase (42.8 ± 3.4 to 45.6 ± 3.2 g/l; <i>P</i> < 0.001), indicating a decrease in inflammation.</p><p><strong>Conclusion: </strong>Empagliflozin showed anti-inflammatory effects by reducing ESR and PLR and increasing serum albumin and lymphocyte count in adults with T2D. Monitoring inflammatory markers can serve as an indicator of treatment effectiveness in T2D patients.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"38 ","pages":"x"},"PeriodicalIF":0.0,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11707716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142951227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Factor Influencing Intimate Partner Violence against Women during COVID-19 Pandemic: A Systematic Review and Meta-Analysis.","authors":"Sulmaz Ghahramani, Bita Najjari, Reza Bayattork, Morteza Arab-Zozani","doi":"10.47176/mjiri.38.104","DOIUrl":"https://doi.org/10.47176/mjiri.38.104","url":null,"abstract":"<p><strong>Background: </strong>It seems that the prevalence of intimate partner violence increased during the COVID-19 pandemic. To investigate the prevalence of different types of IPV and its contributing factors on a global scale during the COVID-19 pandemic.</p><p><strong>Methods: </strong>This is a systematic review and meta-analysis study. This study followed the preferred reporting items for systematic reviews and meta-analyses (PRISMA) checklist. All original studies, written in English that reported the overall prevalence of IPV or at least one type of IPV against women during the COVID-19 pandemic were included in this study. PubMed, Embase, Scopus, and Web of Science databases were searched in July 2023. Our general keywords included \"Intimate Partner Violence\", \"Spouse Abuse\", \"Domestic Violence\", \"COVID-19\", and \"SARS-CoV-2\". We used the Joanna Briggs Institute Checklist to assess the quality of all included studies. We conducted a random effect model for meta-analysis using the Mantel-Haenszel method in comprehensive meta-analysis software Version 3. Each type of IPV is calculated as an event rate with a 95% CI for each variable. The I2 statistic test was used to assess the Heterogeneity.</p><p><strong>Results: </strong>Forty-one studies encompassing 14,615 participants met our eligibility criteria and were included in our study. The overall prevalence of IPV was 31% (95% CI: [24.2, 38.8], <i>P</i> < 0.001). Based on type, the highest rate of IPV in the included studies was reported for psychological type (33%, 95% CI: [23.4, 44.3], <i>P</i> = 0.004). The rates of IPV for economic, physical, and sexual types were 19.1% (95% CI: [12.2, 28.6], <i>P</i> < 0.001), 9.5% (95% CI: [6.8, 13.1], <i>P</i> < 0.001), and 8.5% (95% CI: [6.2, 11.7], <i>P</i> < 0.001), respectively. Age, education level, being pregnant, and marital duration were among the most frequent influencing factors.</p><p><strong>Conclusion: </strong>About one-third of women experienced IPV during the COVID-19 pandemic. Psychological IPV emerged as the most prevalent type in the included studies. The most important factors were environmental, social, economic, cultural, and political factors. Age, education level, marital duration, being pregnant, and marital duration were among the most frequent influencing factors.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"38 ","pages":"104"},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11707718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-effectiveness of Telemedicine Intervention for Acute Myocardial Infarction: A Systematic Review.","authors":"Majid Abedinejad, Mohammad Hadian, Soudabe Behrooj, Saeed Bagheri Faradonbeh, Nadia Saniee","doi":"10.47176/mjiri.38.103","DOIUrl":"https://doi.org/10.47176/mjiri.38.103","url":null,"abstract":"<p><strong>Background: </strong>One of the most important causes of mortality in the world is acute myocardial infarction. There are two general treatments including thrombolytic drugs and percutaneous coronary interventions. But, monitoring outpatient AMI treatment from a remote or rural location has emerged as a successful telemedicine technique. So, the present study aimed to review the economic evaluation studies of telemedicine in patients with acute myocardial infarction.</p><p><strong>Methods: </strong>This study was conducted based on Preferred Reporting Items for Systematic Reviews and Meta-Analysis checklist (PRISMA is a 27-item checklist used to improve transparency in systematic reviews) guidelines in 2022. PubMed, Scopus, Web of Science, Proquest, Iranian databases (SID, Magiran), and Google Scholar were searched with the keywords of telemedicine and myocardial infarction from 2000 to 2022. After eliminating duplicates, titles and abstracts were screened based on inclusion and exclusion criteria, details, and the most important results of eligible studies were recorded in the data collection form.</p><p><strong>Results: </strong>904 records were identified in this search, of which 147 were duplicates. Finally, 6 records were included in this study. Among these studies, 4 were cost-effectiveness, one was cost analysis, and one was cost-utility. The willingness to pay threshold was between 20,000 and 100,000, and the outcomes were measured with QALY (Quality-adjusted life-years). The reviewed studies showed that telemedicine can improve outcomes such as quality of life and reduce disease costs.</p><p><strong>Conclusion: </strong>The results showed that telemedicine interventions for acute myocardial infarction can be helpful, and cost-effective. However in some cases, it can cause increased costs and may not have a significant difference in effectiveness with other methods because of the condition and stage of the disease.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"38 ","pages":"103"},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11707721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Affecting Physical Activity in Iraqi Patients with Lower Limb Amputation.","authors":"Mohammed Flayyih Hassan Al-Falahi, Maryam Jalali, Taher Babaee","doi":"10.47176/mjiri.38.102","DOIUrl":"https://doi.org/10.47176/mjiri.38.102","url":null,"abstract":"<p><strong>Background: </strong>Limb loss can negatively affect the psychological and physical well-being, mobility, and social life of people with lower limb amputation. Participating in physical activities is of great importance for these people. This study aimed to explore factors affecting the physical activity of Iraqi lower-limb amputees.</p><p><strong>Methods: </strong>In this cross-sectional study, the participants were asked to fill out the Oswestry disability index (ODI) questionnaire, the 12-item short-form health survey (SF-12), the Trinity Amputation and Prosthesis Experience Scales (TAPES), and the International Physical Activity Questionnaire (IPAQ). The performance-based Timed Up and Go (TUG) test was also assessed. We used a hierarchical regression model to estimate the effect of some parameters on physical activity considering age, sex, and level of amputation.</p><p><strong>Results: </strong>A total of 376 lower limb amputees, aged 20 to 67 years old, completed the tests. The TUG time (beta = 0.406; <i>P</i> < 0.001), mental component score of the SF-12 (beta = 0.214; <i>P</i> < 0.001), ODI (beta = -0.201; <i>P</i> < 0.001), and physical activity component of SF-12 (beta = 0.131; <i>P</i> = 0.002) had significant associations with physical activity.</p><p><strong>Conclusion: </strong>The TUG time was the most critical factor in predicting physical activity. The mental score component of the SF-12 ranked second, showing the importance of family and social support for amputees in their physical activity and emphasizing the importance of including mental and psychosocial plans in the rehabilitation program of lower limb amputees. Low back pain should be taken seriously in lower limb amputees because of its prevalence and the effect of its related disability on the physical activity of amputees. Residual limb pain was also very prevalent. Although it did not contribute to our model, its negative effect on physical activity should not be underestimated.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"38 ","pages":"102"},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11707717/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastroprotective Effects of Betahistine Against an Indomethacin-Induced Gastric Mucosal Ulcer in Rats: The Role of CINC-2α Gene.","authors":"Shaghayegh Tarani, Gelareh Vahabzadeh, Hasan Fallah Huseini, Armin Khavandegar, Bahareh Tavakoli-Far, Roshanak Jazayeri","doi":"10.47176/mjiri.38.100","DOIUrl":"10.47176/mjiri.38.100","url":null,"abstract":"<p><strong>Background: </strong>The role of histamine H3 receptors (H3Rs) in gastric protection and anti-inflammatory function is controversial. In this study, we investigated the gastroprotective effect of a histamine H3 receptor antagonist drug, betahistine, on cytokine-induced neutrophil chemoattractant (CINC) gene expression in a rat model of indomethacin-induced gastric mucosal injury.</p><p><strong>Methods: </strong>In this experiment, rats were divided into four groups; the control group received no treatment, group 2 was treated with indomethacin at a dose of 25 mg/kg, group 3 pre-treated with famotidine at a dose of 50 mg/kg, and group 4 pre-treated with betahistine (as a reference drug) at a dose of 50 mg/kg. The last two groups were followed by indomethacin administration (25 mg/kg), three days later. The obtained values were expressed as the mean and standard error of the mean (mean ± SEM). The level of statistical significance was set at α = 0.05.</p><p><strong>Results: </strong>Indomethacin treatment resulted in large ulcerative lesions with a mean ulcer index of 29± 13.63 mm. However, ulcerative indices were significantly improved in groups pre-treated with famotidine (15.5 ± 8.68 mm; <i>P</i> < 0.05) and betahistine (11±5.66 mm, <i>P</i> < 0.01), compared to the indomethacin-treated group. The expression levels of gastric CINC-2ɑ were significantly elevated in indomethacin-induced groups by 0.028±0.05 in the indomethacin group, 0.005±0.01 in indomethacin + famotidine, and 0.012±0.03 in indomethacin + betahistine groups, compared to the control group (<i>P</i> < 0.05). Besides, pre-treatment with betahistine significantly reduced the expression of CINC-2ɑ induced by indomethacin administration (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Betahistine for five days before administrating indomethacin reduced the ulcer index and downregulated the expression of CINC-2α significantly. Overall, pre-treatment with betahistine protects against the gastric damage induced by indomethacin by lowering the expression of CINC-2ɑ.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"38 ","pages":"100"},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11644103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Clinical and Pathological Characteristics of Thyroid Cancer Surgery in the Pandemic Era.","authors":"Asma Shafaeipour, Mohammad Shirkhoda, Mohammad Yasin Karami, Fatemeh Moosaie, Amirmohsen Jalaeefar, Maziar Motiee-Langroudi, Iraj Harirchi","doi":"10.47176/mjiri.38.99","DOIUrl":"10.47176/mjiri.38.99","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic brought significant challenges for oncology centers and cancer patients, necessitating the implementation of various preventive and restrictive protocols and postponing elective surgeries. We aimed to assess and compare tumor characteristics, including the size, metastasis, and duration of hospitalizations between the periods before and during COVID-19 in patients with thyroid cancer.</p><p><strong>Methods: </strong>The present cross-sectional study was performed at The Institute of Cancer, Tehran University of Medical Sciences, with 143 patients observed 2 years before the pandemic and 92 during March 2020 and March 2022. Clinical and pathological tumor characteristics were compared between the 2 groups, including surgical details, hospitalization and intensive care unit (ICU) admission durations, time intervals between diagnoses and surgeries, and various metastatic factors. All data were analyzed using SPSS software 21. The chi-square test was used for the statistical analysis of qualitative data, and the t test was used for the statistical analysis of continuous data. <i>P</i> < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>The most frequent tumor type was papillary thyroid cancer (134 [93.7%] and 82 [89.13%]; <i>P</i> = 0.209). The right lobe was the most prevalent tumor site both before and during COVID-19, respectively (55 [38.5%] and 29 [31.5%]; <i>P</i> = 0.278). Central (64 [50.8%] and 62 [49.2%]; <i>P</i> < 0.001), and lateral (45 [34.5%] and 45 [48.9 %]; <i>P</i> = 0.045) lymph node metastasis in the first surgery and recurrence (<i>P</i> = 0.006 and <i>P</i> = 0.022, respectively) were significantly higher in patients admitted during the COVID-19 pandemic, respectively. The mean interval between the first surgery and subsequent surgery due to recurrence (<i>P</i> < 0.001), duration of ICU admission (<i>P</i> = 0.010), and hospitalization after the second operation were significantly lower during the pandemic (<i>P</i> = 0.006).</p><p><strong>Conclusion: </strong>During the COVID-19 pandemic, patients exhibited larger tumors, increased lymph node metastasis, and shorter intervals between surgeries. This underscores the need for healthcare decision-makers to implement effective thyroid cancer management strategies in future outbreaks. Our study stands out by analyzing hospitalization and ICU admissions and duration for each patient, unlike any other study. Moreover, we extended our observation period beyond the typical duration found in most of the literature.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"38 ","pages":"99"},"PeriodicalIF":0.0,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11644028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Relationship between QT Dispersion in ECG and Response to Primary PCI in Patients with Acute Myocardial Infarction.","authors":"Mir Mohammad Sadra Ghods Hosseini, Samira Dodangeh, Hamid Reza Javadi, Alireza Razaghi, Majid Haji Karimi","doi":"10.47176/mjiri.38.98","DOIUrl":"10.47176/mjiri.38.98","url":null,"abstract":"<p><strong>Background: </strong>St-elevation myocardial infarction (STEMI) is a serious condition that occurs when the blood flow to one or more coronary arteries is blocked, leading to damage or death of the heart muscle (myocardial injury or necrosis). The present study aimed to compare QTc and QTd intervals in patients with STEMI before and 90 minutes after treatment in Booali Sina Hospital, Qazvin, Iran.</p><p><strong>Methods: </strong>The present study is an analytical cross-sectional study. Between March 2021 and 2022, 107 patients administered to Booali Sina Hospital, Qazvin, Iran, due to STEMI who underwent primary PCI were enrolled in the study. Data including age, sex, height and weight, disease history, QTc interval before and 90 minutes after treatment, QTd before and 90 minutes after treatment and Ejection fraction values were extracted from the patient's files. Then, the relationship between change in QT and QTd after treatment with response to treatment based on ST Resolution was evaluated. SPSS 20.0 statistical program was used for the statistical analysis. All values are given as mean± standard deviation (SD). A p-value of less than 0.05 was considered as significant.</p><p><strong>Results: </strong>The observed mean difference in investigated variables of patients, including age, height, weight, and BMI, was not statistically significant between the two groups (response to treatment and non-response to treatment (<i>P</i> > 0.05). Findings demonstrated that the mean QTd 1 in the response to the treatment group was higher compared to the non-response to the treatment group, and this difference was not statistically significant (<i>P</i> = 0.337). It is remarkable that the mean QTd 2 in the response to treatment group was statistically significantly lower than the non-response to treatment group (<i>P</i> = 0.002).</p><p><strong>Conclusion: </strong>We showed that QTd in the studied patients after primary angioplasty reduced significantly compared to the QTd before the treatment, so the QTd can be considered as a noninvasive measure of the response to the treatment in patients with STEMI.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"38 ","pages":"98"},"PeriodicalIF":0.0,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11644199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasonographic Evaluation of the Masseter Muscle in Skeletal Malocclusions (Class I, II, and III).","authors":"Mahrokh Imanimoghaddam, Fahimeh Farzanegan, Mohammad Taghi Shakeri, Farzaneh Soleymani, Zahra Jamali Paghaleh","doi":"10.47176/mjiri.38.97","DOIUrl":"10.47176/mjiri.38.97","url":null,"abstract":"<p><strong>Background: </strong>There is limited research on the sonographic view of people with skeletal malocclusions. Therefore, this study aimed to evaluate the sonographic findings of the masseter muscle in patients with skeletal malocclusions.</p><p><strong>Methods: </strong>In this descriptive study, 48 patients aged 15-20 years with skeletal class I, II, and III malocclusions (n = 16) who were referred to Mashhad Dental School for treatment were selected. The masseter muscle was evaluated by ultrasound, including transverse and longitudinal scans on both sides of the face in resting and contraction states. The age, gender, muscle thickness, muscle pattern (Malocclusion were classified based on A-point, nasion, B-point (ANB): 0< ANB <4 as class I, ANB > 4 as class II, ANB < 0 as class III), side of chewing, and body mass index (BMI) parameters were measured for each patient. Paired t-tests compared masseter muscle states; ANOVA assessed differences among malocclusion groups.</p><p><strong>Results: </strong>The most commonly observed pattern in the masseter muscle of patients with class III skeletal malocclusions was type II, and in people with class II malocclusions was type I. There was a positive and significant correlation between the thickness of masseter muscle and BMI in each group separately (<i>P</i> < 0.001). However, the masseter muscle pattern did not show a significant correlation with BMI, gender, and age. A significant difference was observed between the thickness of the masseter muscle in the resting and contracted states in each group (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>This study showed that skeletal malocclusions can affect the pattern and internal structure of the masseter muscle in the anterior-posterior dimension of the face. Ultrasound can be a suitable diagnostic tool for these patients.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"38 ","pages":"97"},"PeriodicalIF":0.0,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11644026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}