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Research Progress on the Synthesis of Flavonoids by Saccharomyces Cerevisiae 酿酒酵母合成黄酮类化合物的研究进展
International Journal of Biology and Life Sciences Pub Date : 2023-05-20 DOI: 10.54097/ijbls.v2i3.8652
Tao Luan
{"title":"Research Progress on the Synthesis of Flavonoids by Saccharomyces Cerevisiae","authors":"Tao Luan","doi":"10.54097/ijbls.v2i3.8652","DOIUrl":"https://doi.org/10.54097/ijbls.v2i3.8652","url":null,"abstract":"As a food-safe microorganism, Saccharomyces cerevisiae is widely studied in metabolic engineering and synthetic biology, and can be used as a cell factory to produce natural compounds. Flavonoids are valuable natural products with multiple biological activities such as estrogen, antioxidant, antibacterial and anticancer activities, and are widely used in food, medicine and other fields. However, the development and utilization of flavonoids is limited by problems such as low concentration and long cycle in obtaining them from plants. With the development of metabolic engineering technology and synthetic biology, the synthesis of flavonoids through microbial cell factories has good prospects. Based on microbial synthesis of flavonoids, this paper comprehensively reviews the research progress of some flavonoids synthesized in S. cerevisiae, summarizes and prospects the current difficulties and challenges as well as future research directions.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128033925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Current Status and Suggestions of Ecological Animal Husbandry in the New Era 新时期生态畜牧业的现状与建议
International Journal of Biology and Life Sciences Pub Date : 2023-05-20 DOI: 10.54097/ijbls.v2i3.8659
Yingxiang Yang
{"title":"Current Status and Suggestions of Ecological Animal Husbandry in the New Era","authors":"Yingxiang Yang","doi":"10.54097/ijbls.v2i3.8659","DOIUrl":"https://doi.org/10.54097/ijbls.v2i3.8659","url":null,"abstract":"The construction of ecological civilization was placed in a prominent position as early as the 18th National Congress of the Communist Party of China in 2012. It must be integrated with social, economic, political, and cultural constructions to build a beautiful China and reverse the continuously deteriorating ecological environment. This has nothing to do with people's well-being and the future of the nation is closely linked. At the same time, at the 19th National Congress of the Communist Party of China in 2019, General Secretary Xi Jinping once again proposed \"adhering to the harmonious coexistence between man and nature\", which shows that our understanding of natural environmental protection has deepened and our determination to strengthen the construction of ecological civilization has become firmer. In the new era, in order to promote the construction of ecological civilization, it is necessary to change the traditional animal husbandry model, vigorously develop ecological breeding, and implement the concept of green and sustainable development. The purpose of this article is to make a brief summary of ecological animal husbandry and make suggestions.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125862764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Efficacy of Neoadjuvant Endocrine Therapy in Non-Metastatic Prostate Cancer and Preliminary Experiences of Bone Metastasis Patients 新辅助内分泌治疗非转移性前列腺癌的临床疗效及骨转移患者的初步经验
International Journal of Biology and Life Sciences Pub Date : 2023-05-20 DOI: 10.54097/ijbls.v2i3.8661
Yu Jiang, Qiao Xu, Shihao Wan, Yun-feng He
{"title":"Clinical Efficacy of Neoadjuvant Endocrine Therapy in Non-Metastatic Prostate Cancer and Preliminary Experiences of Bone Metastasis Patients","authors":"Yu Jiang, Qiao Xu, Shihao Wan, Yun-feng He","doi":"10.54097/ijbls.v2i3.8661","DOIUrl":"https://doi.org/10.54097/ijbls.v2i3.8661","url":null,"abstract":"Objective To explore the short-term efficacy of neoadjuvant endocrine therapy (NET) for localized prostate cancer and preliminary exploration of NET in patients with bone metastases. Methods Analyze clinical data of patients undergoing radical prostatectomy (RP) in the First Affiliated Hospital of Chongqing Medical University from January 2017 to January 2021 retrospectively. Patients with localized prostate cancer undergoing NET+RP were selected as the experimental group. The ones who only received RP were chosen as the control group, and the peri- and post-operative outcomes such as down-staging, pathological complete response, positive margin, intraoperative blood loss, and operation time were compared between the two groups. In addition, collect the information of patients with bone metastatic prostate cancer, excluding organ metastases, who received NET+RP over the same time-period and analyzed the short-term efficacy and quality of life. Results In the experimental group, there were more down-staging (13.08% vs. 4.67%, P=0.031), more pathological complete response (12.15% vs. 0.93%, P=0.001), less positive margin (9.35% vs. 29.91%, P< 0.001) and less blood loss (171.45±16.19 vs. 177.76±23.28, P=0.022). NET+RP also showed a satisfying short-term efficacy in patients with bone metastases, with well quality of life. Conclusion NET combined with RP can provide good short-term prognosis and patient satisfaction in patients with prostate cancer, and it is a potential option for patients with bone metastases without organ metastases.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127978931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of the Current Situation and Trends of the Development of Big Health Industry 大健康产业发展现状及趋势分析
International Journal of Biology and Life Sciences Pub Date : 2023-05-20 DOI: 10.54097/ijbls.v2i3.8656
Hanson Qian
{"title":"Analysis of the Current Situation and Trends of the Development of Big Health Industry","authors":"Hanson Qian","doi":"10.54097/ijbls.v2i3.8656","DOIUrl":"https://doi.org/10.54097/ijbls.v2i3.8656","url":null,"abstract":"The medical and health industry aims to maintain and promote people's physical and mental health, including medical services, health management and promotion, health insurance and related services. Compared with the traditional health industry, the big health industry does not sell a single product, but provides solutions for people to live a healthy life, thus creating greater business opportunities. The report of the 19th National Congress stressed the development of the health industry and the building of a healthy China. Health industry is an emerging industry with huge market potential, and it has the characteristics of \"broad employment prospects, large consumption demand, and promoting the health and longevity of citizens\".","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129934278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Microstructure and Mechanical Properties Analysis of Multi-walled Carbon Nanotubes/Polyvinyl Alcohol Conducting Hydrogel Electrode Film 多壁碳纳米管/聚乙烯醇导电水凝胶电极膜的微观结构与力学性能分析
International Journal of Biology and Life Sciences Pub Date : 2023-05-20 DOI: 10.54097/ijbls.v2i3.8655
Shumin Liu, Jia Chen, Jinpeng Sun
{"title":"Microstructure and Mechanical Properties Analysis of Multi-walled Carbon Nanotubes/Polyvinyl Alcohol Conducting Hydrogel Electrode Film","authors":"Shumin Liu, Jia Chen, Jinpeng Sun","doi":"10.54097/ijbls.v2i3.8655","DOIUrl":"https://doi.org/10.54097/ijbls.v2i3.8655","url":null,"abstract":"According to the good conductivity and electrocatalytic activity of nano platinum and multi-walled carbon nanotubes (MWCNTs) and the hydrogel properties of polyvinyl alcohol (PVA), MWCNTs and PVA double-network porous hydrogels were designed and prepared. The surface of the conductive hydrogel electrode film formed a three-dimensional porous structure, and the stacking of the PVA-coated MWCNTs formed a nanoscale micropore structure. However, the micropore network structure inside the electrode film was not obvious, which was the reason why the electrode film did not selectively catalyzed glucose. The elastic modulus of PtNPs/MWCNTs/PVA electrode film is consistent with that of PVA. Its modulus of elasticity is close to that of human tissue.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130444645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low-cost Fermentation of Polyhydroxyfatty Acid Esters 聚羟基脂肪酸酯的低成本发酵
International Journal of Biology and Life Sciences Pub Date : 2023-05-20 DOI: 10.54097/ijbls.v2i3.8665
Xin Zhen, Chung-hua Li
{"title":"Low-cost Fermentation of Polyhydroxyfatty Acid Esters","authors":"Xin Zhen, Chung-hua Li","doi":"10.54097/ijbls.v2i3.8665","DOIUrl":"https://doi.org/10.54097/ijbls.v2i3.8665","url":null,"abstract":"With the depletion of traditional fossil energy and environmental problems, there is an urgent need for alternative materials. Biosynthesis not only achieves low-carbon green economy, but also reduces energy consumption. Polyhydroxyfatty acid ester is a kind of material with excellent performance, but the production cost is high, mainly due to the high cost of fermentation carbon source, fermentation process and other factors. Using waste as substrate not only reduces fermentation costs but also solves environmental problems. On the other hand, mixed strains can be used simultaneously to reduce the cost of fermentation.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133989459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progress in Metastasis and Treatment of Osteosarcoma 骨肉瘤的转移及治疗进展
International Journal of Biology and Life Sciences Pub Date : 2023-05-20 DOI: 10.54097/ijbls.v2i3.8651
T. Song
{"title":"Progress in Metastasis and Treatment of Osteosarcoma","authors":"T. Song","doi":"10.54097/ijbls.v2i3.8651","DOIUrl":"https://doi.org/10.54097/ijbls.v2i3.8651","url":null,"abstract":"Osteosarcoma is a primary malignant tumor originating from mesenchymal tissue. It has the characteristics of high malignancy, easy metastasis (common lung metastasis) and poor prognosis. Metastasis is the main cause of treatment failure and poor prognosis. Although the treatment of osteosarcoma has made some progress in these decades, the 5-year survival rate of patients with metastasis has not increased much. This review explores the molecular mechanism of osteosarcoma metastasis, the current research progress of therapeutic drugs, immunotherapy and targeted therapy, and provides ideas for the treatment of osteosarcoma.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121289159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment Theories of Cervical Radiculopathy with Traditional Chinese Medicine 颈神经根病的中医治疗理论
International Journal of Biology and Life Sciences Pub Date : 2023-05-20 DOI: 10.54097/ijbls.v2i3.8649
Jiahui Qin, Xintong Wang, Shu Yang, Kaiping Li
{"title":"Treatment Theories of Cervical Radiculopathy with Traditional Chinese Medicine","authors":"Jiahui Qin, Xintong Wang, Shu Yang, Kaiping Li","doi":"10.54097/ijbls.v2i3.8649","DOIUrl":"https://doi.org/10.54097/ijbls.v2i3.8649","url":null,"abstract":"Cervical radiculopathy (CR) is a common disease of cervical spine, which is mainly caused by neurodegeneration, middle-aged and old people, and is senility disease. The main clinical manifestations were stiff neck and shoulder pain, limitation of movement, upper limb soreness, radiation pain, numbness and abnormal sensation. This article summarizes the treatment of cervical radiculopathy with traditional Chinese medicine and western medicine by exploring the etiology and main clinical analysis index of nerve root disease.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122926251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Toxic effects of chemical plant residues on soil 化学植物残留物对土壤的毒性作用
International Journal of Biology and Life Sciences Pub Date : 2023-04-09 DOI: 10.54097/ijbls.v2i2.7197
Yilun Dai, Liheng Xia
{"title":"Toxic effects of chemical plant residues on soil","authors":"Yilun Dai, Liheng Xia","doi":"10.54097/ijbls.v2i2.7197","DOIUrl":"https://doi.org/10.54097/ijbls.v2i2.7197","url":null,"abstract":"Soil samples were collected from 6 different areas of the abandoned pesticide factory site, numbered p1, p2, p3, p4, p5, and p6, respectively. Based on the acute toxicity of Luminescent bacteria and Flea and the genotoxicity of Vicia faba root tip micronucleus, the ecotoxicological diagnosis of soil extracts from 6 samples was carried out. The results showed that the relative luminosity of the 6 kinds of extracts to luminescent bacteria were 50.7%, 56.3%, 43.7%, 53.0%, 49.6% and 67.6%, respectively. The 48-hour acute toxicity EC50 of the large flea was 6.15%, 8.65%, 0.57%, 2.52%, 0.33% and 14.94%, respectively. The results of the photobacterial experiment were basically consistent with the acute toxicity results of Flea daphnia, and the results showed that the soil pollution of the pesticide factory site was relatively serious.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130020328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research on social service model of youth vision protection 青少年视力保护社会服务模式研究
International Journal of Biology and Life Sciences Pub Date : 2023-04-08 DOI: 10.54097/ijbls.v2i2.7179
Zeyu Zhang, Zechun Li
{"title":"Research on social service model of youth vision protection","authors":"Zeyu Zhang, Zechun Li","doi":"10.54097/ijbls.v2i2.7179","DOIUrl":"https://doi.org/10.54097/ijbls.v2i2.7179","url":null,"abstract":"Adolescent vision protection has always been a focus of social concern. With the rapid development of modern technology and changes in social lifestyles, adolescents are generally facing risks to their visual health. This paper explores the social service model of youth vision protection through a review of existing literature and questionnaire analysis. Firstly this study aims to analyze and explore the current situation of prevention and control of youth and adolescent vision and the impact of social service models on it through theoretical studies of literature, with the aim of establishing a more complete vision protection system and improving the sustainability and effectiveness of social services for adolescent vision protection. In addition, this paper introduces the current social service model of youth vision protection, including services at school, family and community levels, and discusses the home-school-community linkage model and its construction method, and finally puts forward suggestions for the future social service model of youth vision protection. After the investigation and research, we found that youth vision protection is a complex social issue that requires the joint efforts of the whole society. Through social service models at different levels, comprehensive vision protection services can be provided to adolescents to promote their healthy growth. This study has some reference value for improving the quality of social services for vision protection and enhancing the intervention effects on adolescent vision protection.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132161814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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