Lasers in Medical Science最新文献

{"title":"Evaluating the efficacy of femtosecond laser-assisted arcuate keratotomy in correcting low-to-moderate astigmatism during femtosecond laser-assisted cataract surgery in Chinese patients.","authors":"Xue Ding, Shaowei Li, Fan Zhang, Chenxi Hu, Ruihua Zhao, Weikang Bi, Daguang Bi, Qiumei Li","doi":"10.1007/s10103-025-04394-y","DOIUrl":"https://doi.org/10.1007/s10103-025-04394-y","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the astigmatism correcting effect of the femtosecond laser-assisted arcuate keratotomy (FSAK) during femtosecond laser-assisted cataract surgery (FLACS) in Chinese people.</p><p><strong>Methods: </strong>The retrospective study included consecutive patients who underwent combined FSAK and FLACS, with corneal astigmatism of 0.75 to 2.25 diopters (D). Three vectors of astigmatism were analyzed using the Alpines vector analysis: target-induced astigmatism (TIA), surgically induced astigmatism (SIA), and difference vector (DV). The correction index (CI), angle of error (AE), magnitude of error (ME), and coefficient of adjustment (CA) were calculated. Corneal astigmatism was measured before and 3 months after surgery.</p><p><strong>Results: </strong>A total of 129 eyes from 107 patients were enrolled. The corneal astigmatism was significantly reduced from 1.34 ± 0.36 D to 0.69 ± 0.47 D (P < 0.001). The TIA was 1.36 ± 0.37 D, the SIA was 1.16 ± 0.69 D, and the DV was 0.7 ± 0.47 D. The ME (difference between SIA and TIA) was - 0.2 ± 0.65 D, and the CI (ratio of SIA to TIA) was 0.86 ± 0.49. The CA (inverse of the CI) was 1.79 ± 1.65. The AE was - 0.02° ± 18.33°. The corneal astigmatism significantly decreased in all axes of astigmatism (P < 0.001). Postoperatively, the residual astigmatism magnitudes were 0.76 ± 0.44 D in with-the-rule (WTR), 0.63 ± 0.51 D in against-the-rule (ATR), and 0.62 ± 0.44 D in oblique (OBL). The CI values were 0.65 ± 0.31, 1.22 ± 0.52, and 0.80 ± 0.40 in WTR, ATR, and OBL, respectively.</p><p><strong>Conclusion: </strong>The modified FSAK for Chinese cataract patients effectively and safely reduced corneal astigmatism.</p>","PeriodicalId":17978,"journal":{"name":"Lasers in Medical Science","volume":"40 1","pages":"142"},"PeriodicalIF":2.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of different Raman spectrometer models in the quantification of blood serum analytes.","authors":"Hector Enrique Giana, Luisa Oliveira Souza, Landulfo Silveira","doi":"10.1007/s10103-025-04413-y","DOIUrl":"https://doi.org/10.1007/s10103-025-04413-y","url":null,"abstract":"<p><p>The analytical performance of three commercial Raman spectrometers in determining the concentrations of analytes associated with diagnosing metabolic, cardiovascular, and renal disorders has been compared. Two portable and one benchtop spectrometers were tested to predict the serum concentrations of triglycerides (TRI), cholesterol (COL), high-density cholesterol, creatinine, urea, and glucose in 193 serum samples using partial least squares (PLS) regression and PLS discriminant analysis, the latter for classifying samples as either altered or within reference values. Strong correlations (r > 0.81) were obtained for TRI and COL analytes using the benchtop and one of the portable spectrometers, and the classification accuracy rates exceeded 90%, suggesting potential for use in clinical screening. Adding a glucose solution improved the correlation and the root mean square error for TRI and COL analytes; however, it did not enhance the correlation or error for the glucose analyte. Raman spectroscopy showed potential to support routine laboratory activities and may have applications in clinical screening.</p>","PeriodicalId":17978,"journal":{"name":"Lasers in Medical Science","volume":"40 1","pages":"143"},"PeriodicalIF":2.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effectiveness of nitrogen plasma skin rejuvenation in the treatment of acne vulgaris in Asians.","authors":"Kento Takaya, Kazuo Kishi","doi":"10.1007/s10103-025-04381-3","DOIUrl":"https://doi.org/10.1007/s10103-025-04381-3","url":null,"abstract":"<p><p>Reports on the use of plasma skin regeneration for the treatment of acne vulgaris are limited. We aimed to report on the effectiveness of nitrogen PSR in the treatment of acne vulgaris. Participants with acne vulgaris were enrolled and underwent three consecutive PSR sessions at 4-week intervals. Facial surface analysis was performed as an evaluation of treatment efficacy through objective computerized evaluation using the Canfield VISIA imaging system. Post-treatment subjective evaluations were performed and analyzed using the Clinical Global Impression Improvement Scale (CGI-I) and the Patient Global Impression Improvement Scale (PGI-I). Pain levels and other complications were recorded at each follow-up visit. At 2 months after the final treatment, the patients' subjective evaluation of the treatment was obtained. Twenty patients were included in the analysis. There was a significant improvement in the porphyrin VISIA System score and in the erythematous area. Additionally, the fine lines, pores, and skin texture showed significant improvements after three sessions, and both the mean CGI-I and PGI-I scores improved significantly. Two patients experienced temporary acne worsening; however, no other side effects were observed. All patients were satisfied with the treatment and did not report any significant adverse effects on their lifestyle. Nitrogen PSR is an effective and safe treatment for inflammatory acne, with minimal recovery time and no significant complications.</p>","PeriodicalId":17978,"journal":{"name":"Lasers in Medical Science","volume":"40 1","pages":"141"},"PeriodicalIF":2.1,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the correlation between fluorescence-featured intraoral scanner, laser fluorescence and spectrophotometric analyses in caries-affected dentin: an in-vitro diagnostic accuracy study.","authors":"Özlem Kanar, Bora Korkut, Dilek Tağtekin","doi":"10.1007/s10103-025-04390-2","DOIUrl":"10.1007/s10103-025-04390-2","url":null,"abstract":"<p><p>To investigate the relation between the caries scoring system of the fluorescence intraoral scanner (IOS) Trios 4 (3Shape, Denmark)a red laser light-induced fluorescence device DIAGNOdent Pen (Kavo, Germany), and the color parameters (L*a*b*) by a clinical contact type hybrid spectrophotometer Rayplicker (Borea, France) in the assessment of caries affected dentin tissue. Caries lesions were minimally invasively removal from 186 extracted molars. Teeth were scanned using Trios4, and the integrated software scored the cavity floor regarding the colors (yellow, initial caries; red, moderate-extensive caries) depending on the fluorescence features. Then the DIAGNOdent measurements were obtained from each cavity's deep and discolored surface points following the previously obtained Trios4 colors. Thus, the Trios4 reading could be quantitatively assessed. Cross-polarization photographs were using the Rayplickerand L*a*b color parameters, and 3D Master (VITA) color mapping was obtained by using the RayPlicker's software. Spearman's Rho Correlation, Kappa, Mann Whitney-U, One-way Analysis-of-Variance, and Kruskal Wallis tests were used for the statistical analyses (P < 0.05). Sensitivity, specificity and AUC were calculated. Trios4 and DIAGNOdent were positively correlated (r = 0.733;P < 0.001). The L*parameter by Rayplicker and Trios4 was negatively correlated(r=-0.742;P < 0,001). The a*parameter by Rayplicker and Trios4 scoring positively correlated(r = 0.552;P < 0.001). No significant correlation was observed between b*parameter by Rayplicker and Trios4 (r = 0.023; P = 0.760). DIAGNOdent readings according toTrios4 scorings were significant (P < 0.001). The teeth without caries scored by the Trios4 corresponded to the median value of 29 in DIAGNOdent readings, and 88 for the teeth with caries (by Trios4 / yellow-red). The agreement between the Trios4 and DIAGNOdent was 52.2% for the specimens with no residual caries. The presence of caries scores by the Trios 4 corresponded to the DIAGNOdent readings of %100 for all the teeth evaluated. Regarding the RayPlicker assessments, 33% of the sound cavities corresponded to 2M3 color, and 73% corresponded to 5M3 color. Trios4 scorings presented 0.782 AUC, 56.30% sensitivity, and 100% specificity in DIAGNOdent reference. Trios4 scoring was considered coherent with the DIAGNOdent Pen. DIAGNOdent readings and the Level of L* and a* parameters in the dentin tissue might be considered interrelated. Fluorescence-featured scanner devices can be useful clinical tools to evaluate remaining dentin tissue during the caries removal procedure.</p>","PeriodicalId":17978,"journal":{"name":"Lasers in Medical Science","volume":"40 1","pages":"140"},"PeriodicalIF":2.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative efficacy and safety of greenlight laser vaporization, anatomical vaporization, and enucleation for benign prostatic hyperplasia: a systematic review and meta-analysis.","authors":"Min Wang, Shiqi Chen, Yu Xi, Nanxiang Huang, Li Zhang, Jinlong Liu","doi":"10.1007/s10103-025-04389-9","DOIUrl":"https://doi.org/10.1007/s10103-025-04389-9","url":null,"abstract":"<p><p>This study compares the surgical and functional outcomes of photoselective vaporization of the prostate (PVP), anatomical PVP (aPVP), and Greenlight laser enucleation of the prostate (GreenLEP) in the treatment of benign prostatic hyperplasia (BPH). A comprehensive search was conducted in February 2024 across PubMed, the Cochrane Library, and EMBASE databases, following PRISMA guidelines and registered with PROSPERO (CRD42024518321). Thirteen studies were included, with 11 analyzed in the meta-analysis. Compared to PVP, aPVP had longer operation times (MD: -11.42 min, 95% CI: -15.70 to -7.14, p < 0.00001), higher energy utilization (MD: -56.83 kJ, 95% CI: -61.16 to -52.50, p < 0.00001), and greater energy density (MD: -0.57 kJ/mL, 95% CI: -0.75 to -0.39, p < 0.00001). GreenLEP showed superior energy efficiency (MD: 212.95 kJ, 95% CI: 40.41 to 385.50, p = 0.02) and functional outcomes, particularly in Qmax, PVR, and PSA levels at final follow-up. GreenLEP also had the lowest re-operation rate (OR: 27.30, 95% CI: 8.52 to 87.51, p < 0.00001) and was most effective for larger prostates. No significant differences in early, late, or major complications were observed across techniques. This meta-analysis highlights that aPVP and GreenLEP offer superior functional and efficiency benefits compared to PVP while maintaining comparable safety. GreenLEP is particularly advantageous for larger prostates, providing an effective and safe alternative.</p>","PeriodicalId":17978,"journal":{"name":"Lasers in Medical Science","volume":"40 1","pages":"139"},"PeriodicalIF":2.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An ex vivo experimental study comparing the effects of the holmium: yttrium-aluminum-garnet and thulium fiber lasers on testicular tissue.","authors":"Mustafa Karaaslan, Mehmet Yilmaz, Melike Ordu, Mehmet Emin Sirin","doi":"10.1007/s10103-025-04388-w","DOIUrl":"https://doi.org/10.1007/s10103-025-04388-w","url":null,"abstract":"<p><p>The effects of lasers on testicular tissue have not yet been investigated in detail. In this experimental ex vivo study, we aimed to demonstrate and compare the effects of the holmium:yttrium-aluminum-garnet (Ho:YAG) and thulium fiber laser (TFL) lasers on testicular tissue. An ex vivo experiment was performed using calf testes. A 100W Ho:YAG laser and a 60W TFL devices with a setting spectrum at 10-60W, a frequency of 20-40 Hz, energy levels at 0.5-1-1.5 J, and medium pulse duration were tested. Histopathological parameters such as Incision depth (ID), vaporization area (VA), coagulation area (CA), and total laser area (TLA = VA + CA) were evaluated. In testicular tissue without a tunica layer, a statistically significant difference was found in the mean VA and TLA values between the Ho:YAG and TFL, in favor of Ho:YAG (p = 0.003, p = 0.003, respectively). In testicular tissue with a tunica layer, there was a statistically significant difference in mean VA, CA, TLA, ID values between Ho:YAG and TFL, in favor of Ho:YAG (all p < 0.001). At 1.5 J-20 Hz and 1.5 J-40 Hz, we observed that the features indicating tissue dissection, such as VA and ID, were lower in the TFL than those in Ho:YAG, while CA values were higher. VA, CA, TLA, ID values were significantly increased in tissue with tunica compared to non-tunicated tissue in both the Ho:YAG and TFL applications. At 30W and 60W, the penetrative effect of the TFL on tissue was less than that of the Ho:YAG, but its coagulation property was superior. What is Known: • Ho:YAG and TFL lasers are widely used in urology, primarily for stone and prostate surgeries, with established tissue effects in these contexts. What is New: • This study is the first to examine and compare the histopathological effects of these lasers on testicular tissue, providing insights into their potential applications in testicular surgery.</p>","PeriodicalId":17978,"journal":{"name":"Lasers in Medical Science","volume":"40 1","pages":"138"},"PeriodicalIF":2.1,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fractional carbon dioxide laser treatment of hypertrophic scar clinical and histopathological evaluation.","authors":"Zaynab Sayed Keshk, Manal Mohammad Salah, Nevien Ahmed Samy","doi":"10.1007/s10103-025-04371-5","DOIUrl":"10.1007/s10103-025-04371-5","url":null,"abstract":"<p><p>Hypertrophic scar could be associated with several complications that interfere with patient daily activities, physical and psychological health and impact patient quality of life. Several therapeutics and maneuvers are used for treatment of hypertrophic scar with variable success and side effects. We aim to evaluate safety and efficacy of fractional carbon dioxide laser on treatment of hypertrophic scar both clinically and histopathologically. Hypertrophic scars in each patient of total thirty patients were subjected to random division with sealed envelope into two parts, part A treated with fractional carbon dioxide laser every month for 5 sessions, and part B lift without treatment for control. Hypertrophic scars in each patient were single or multiple, Single scar was more than 15 cm length. Clinical evaluation was done by two blinded dermatologists, using Vancouver Scar Scale (VSS) and Patient and Observer Scar Assessment Scale (POSAS) for each part before, 3 months and 6 months after treatment. Histopathological evaluation was done for each part before and 3 months after treatment by measuring epidermal thickness, collagen area percent, and elastin area percent. The upper significant clinical and histopathological improvement was shown in carbon dioxide laser treated parts than control parts without significant side effects for fractional carbon dioxide laser treatment. Treatment of hypertrophic scar with fractional carbon dioxide laser is beneficial and generally considered safe, with minimal risk of harm when performed with appropriate laser parameters for male and female patients with skin type III and IV, at different ages and different body regions.</p>","PeriodicalId":17978,"journal":{"name":"Lasers in Medical Science","volume":"40 1","pages":"137"},"PeriodicalIF":2.1,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11897074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the effects of laser photobiomodulation at wavelength of 660 nm and 808 nm in full-thickness burns in rats: a pre-clinical study.","authors":"Juliana Narcizo Kuamoto, Vitória Gonzaga Acerbi, Gabriela Saab Sampaio, Anne Missrie, Livia Assis, Fernando Anselmo Oliveira, Elaine Caldeira Oliveira Guirro, Patricia Brassolatti, Ana Laura Martins de Andrade","doi":"10.1007/s10103-025-04391-1","DOIUrl":"https://doi.org/10.1007/s10103-025-04391-1","url":null,"abstract":"<p><p>Third-degree burns are severe thermal injuries that require prolonged recovery periods and are associated with significant sequelae. Photobiomodulation therapy (PBMT) has emerged as a promising approach for treating skin injuries, although parameter selection remains controversial. This study investigated the effects of PBMT using red (wavelength 660 nm) and infrared (wavelength 808 nm) lasers on tissue repair in third-degree burns in rats. Twenty-four male Wistar rats were divided into three groups: control group (CG, laser off), red laser group (RLG, 660 nm), and infrared laser group (IRLG, 808 nm). Treatments were performed three times per week for 21 days, totaling nine applications, with parameters of 3 J energy, 100 mW power, and 5 points distributed around the lesion. Both the RLG and IRLG groups demonstrated faster wound healing and better tissue organization compared to the CG, along with increased collagen deposition. The IRLG group showed superior histological results, indicating greater efficiency in tissue repair. This study demonstrates the effectiveness of PBM with red (660 nm) and infrared (808 nm) lasers in accelerating full-thickness burn healing in rats, with 808 nm showing superior results. The findings highlight PBM's potential in enhancing collagen synthesis and its promise as a therapy for burn recovery.</p>","PeriodicalId":17978,"journal":{"name":"Lasers in Medical Science","volume":"40 1","pages":"136"},"PeriodicalIF":2.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kinematic and sensory-motor analysis of the effects of treatments with photobiomodulation in rats with experimentally induced spinal injury.","authors":"Luis FIlipe Karatanasov Beloni, Leonardo Borges de Lima, Débora Campos Chaves Correia, Alessandro Corrêa Mendes, Luciana Barros Sannt'Anna, Emilia Angela Lo Schiavo Arisawa, Fernanda Pupio Silva Lima, Mario Oliveira Lima","doi":"10.1007/s10103-025-04399-7","DOIUrl":"https://doi.org/10.1007/s10103-025-04399-7","url":null,"abstract":"<p><p>The aim of this study was to evaluate the kinematic and sensorimotor parameters after application of photobiomodulation (PBM) in rats with experimentally induced spinal cord injuries (SCI). The animals were randomly divided into 3 experimental groups containing 5 animals each and respecting the following arrangement: C (control, simulation of surgical procedures); I (injury, induction of SCI) and PBM (photobiomodulation, SCI + application of photobiomodulation therapy). All animals underwent movement tests after 3, 7, 10 and 14 days, respectively, after the surgical procedure, and the following movement parameters were evaluated: mean velocity (MV), ground reaction force (GRF) and sciatic functional index (SFI) using integrated equipment capable of digitally collecting the proposed data. The mean results of the MV data obtained by groups C, I and PBM were compared and a statistically significant difference was found, being: C x I (p = 0.001) and I x PBM (p = 0.002), respectively. Considering the SFI data obtained by groups C, I and PBM, a statistically significant difference was observed when comparing C x I (p = 0.011). The mean results of the GRF data obtained by groups C, I and PBM were compared and the results showed a statistically significant difference in C x I (p = 0.001), C x PBM (p = 0.026) and I x PBM (p = 0.002), respectively. Therefore, there was an improvement in motor function between the 7th and 14th day after SCI, represented by the increase in speed and better GRF distribution in the PBM group.</p>","PeriodicalId":17978,"journal":{"name":"Lasers in Medical Science","volume":"40 1","pages":"134"},"PeriodicalIF":2.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of photobiomodulation on monocyte dynamics and cytokine levels following plyometric exercise in physically active men.","authors":"Igor Martins Silva, Lucas Schipper, Fabio Santos de Lira, Tiago Kiefer, Pedro Roosevelt Torres Romão, Gilson Pires Dorneles, Alessandra Peres","doi":"10.1007/s10103-025-04386-y","DOIUrl":"https://doi.org/10.1007/s10103-025-04386-y","url":null,"abstract":"<p><p>Photobiomodulation (PBMT) has been investigated as a non-invasive approach to modulate inflammation and muscle recovery, especially after intense exercise. This study aimed to evaluate the impact of PBMT on the dynamics of monocyte subpopulations and cytokine levels after a plyometric exercise session in physically active men aged 18-25 years. This randomized, double-blind, placebo-controlled study, 22 participants were divided into PBMT and placebo groups. Blood samples were collected before, immediately after, and 72 h post-exercise. Monocyte subpopulations were analyzed by flow cytometry, while cytokine levels (TNF-α and MCP-1) were quantified using enzyme-linked immunosorvent assays (ELISA). Plyometric exercise increases classic monocytes (CD14 + CD16-) at 72 h compared in the PBMT group (+ 2,38% p = 0.035). Intermediate monocytes (CD14 + CD16 +), increase immediately after (p < 0.001) and 72 h (PTBM + 21,43%; placebo + 36%; p = 0.023) after exercise in the both group; Non-classical monocytes (CD14-CD16 +) showed differences between groups at 72 h (11,11%; p = 0.002). Exercise increased TNF-α and MCP-1 levels immediately after (p < 0.01 for both groups). PBMT reduced TNF-α levels below baseline at 72 h (-12,50%; p = 0.035), while MCP-1 remained elevated in the placebo group (+ 27,78%; p < 0.035). Differences in MCP-1 changes (Δ%) were observed 72 h post-exercise (p = 0.03). These findings suggest that PBMT attenuates inflammation and promotes immune recovery after exercise.</p>","PeriodicalId":17978,"journal":{"name":"Lasers in Medical Science","volume":"40 1","pages":"135"},"PeriodicalIF":2.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}