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Real-World Tolvaptan Use in Autosomal Dominant Polycystic Kidney Disease: Insights from Two US Medical Centers. 托伐普坦在常染色体显性多囊肾病中的实际应用：来自两个美国医学中心的见解
IF 3
Kidney360 Pub Date : 2025-09-01 Epub Date: 2025-04-22 DOI: 10.34067/KID.0000000816
Vinamratha Rao, Shahed Ammar, Abrar Alshorman, Michelle Fravel, Kerri A McGreal, Franz T Winklhofer, Lama Noureddine, Diana I Jalal, Alan S L Yu, Reem A Mustafa
{"title":"Real-World Tolvaptan Use in Autosomal Dominant Polycystic Kidney Disease: Insights from Two US Medical Centers.","authors":"Vinamratha Rao, Shahed Ammar, Abrar Alshorman, Michelle Fravel, Kerri A McGreal, Franz T Winklhofer, Lama Noureddine, Diana I Jalal, Alan S L Yu, Reem A Mustafa","doi":"10.34067/KID.0000000816","DOIUrl":"10.34067/KID.0000000816","url":null,"abstract":"","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":" ","pages":"1522-1531"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12483031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pain Management in Autosomal Dominant Polycystic Kidney Disease: Clinical Challenges and a Stepwise Algorithmic Approach. 常染色体显性多囊肾病的疼痛管理：临床挑战和逐步算法方法。
IF 3
Kidney360 Pub Date : 2025-09-01 Epub Date: 2025-07-07 DOI: 10.34067/KID.0000000907
Abdul Hamid Borghol, Fadi George Munairdjy Debeh, Ahmad Ghanem, Marie Therese Bou Antoun, Vineetha Rangarajan, Jonathan Mina, Mohamed Hassanein, Lyle W Baker, Sahil Gupta, Shennen A Mao, Christy L Hunt, Marie C Hogan, Michael A Mao, Fouad T Chebib
{"title":"Pain Management in Autosomal Dominant Polycystic Kidney Disease: Clinical Challenges and a Stepwise Algorithmic Approach.","authors":"Abdul Hamid Borghol, Fadi George Munairdjy Debeh, Ahmad Ghanem, Marie Therese Bou Antoun, Vineetha Rangarajan, Jonathan Mina, Mohamed Hassanein, Lyle W Baker, Sahil Gupta, Shennen A Mao, Christy L Hunt, Marie C Hogan, Michael A Mao, Fouad T Chebib","doi":"10.34067/KID.0000000907","DOIUrl":"10.34067/KID.0000000907","url":null,"abstract":"<p><p>Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic kidney disorder. It is primarily caused by pathogenic variants in the PKD1 or PKD2 genes. This leads to the development of numerous kidney cysts, which can result in kidney enlargement and progression to kidney failure. Pain is a common symptom in ADPKD and can negatively affect quality of life (QOL). This pain is often due to the continuous growth of kidney and liver cysts or associated cystic complications. We present a case of a 29-year-old woman with ADPKD who experienced chronic, refractory right-sided flank pain that significantly affected her QOL. Her pain persisted despite taking daily multimodal analgesics and undergoing multiple invasive interventions. She had an unusual asymmetric disease with the right kidney accounting for only 24% of her kidney function. After exhausting all other pain control strategies, she underwent right nephrectomy and partial hepatectomy, which led to substantial improvement in pain and QOL. This review describes the causes, manifestations, and management strategies for abdominal and/or flank pain in ADPKD, including a practical stepwise algorithm to guide clinicians in managing pain and improve QOL of patients with ADPKD. Pain in ADPKD can either be acute or chronic and can lead to significant physical and psychologic distress. Effective pain management in ADPKD requires a multidisciplinary approach, incorporating both nonpharmacologic and pharmacologic interventions such as gabapentin or tolvaptan in select cases. Interventions considered in ADPKD pain control include cyst aspiration with sclerotherapy, celiac plexus blockade, spinal cord stimulation, renal denervation, or nephrectomy.</p>","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":" ","pages":"1618-1631"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12483046/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144584286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibody-Based Imaging of Lymphatic Architecture in Murine Kidneys. 基于抗体的小鼠肾脏淋巴结构成像。
IF 3
Kidney360 Pub Date : 2025-09-01 Epub Date: 2025-08-08 DOI: 10.34067/KID.0000000919
Arin L Melkonian, Gelare Ghajar-Rahimi, Malgorzata M Kamocka, Tarek M El-Achkar, Timmy C Lee, James F George, Anupam Agarwal
{"title":"Antibody-Based Imaging of Lymphatic Architecture in Murine Kidneys.","authors":"Arin L Melkonian, Gelare Ghajar-Rahimi, Malgorzata M Kamocka, Tarek M El-Achkar, Timmy C Lee, James F George, Anupam Agarwal","doi":"10.34067/KID.0000000919","DOIUrl":"10.34067/KID.0000000919","url":null,"abstract":"","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":" ","pages":"1586-1595"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12483051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144804286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Selenium Heist: Uremic Toxins Orchestrate Kidney Ferroptotic Stress in CKD. 硒盗窃：尿毒症毒素在CKD中协调肾脏铁致应激。
IF 3
Kidney360 Pub Date : 2025-09-01 Epub Date: 2025-09-25 DOI: 10.34067/KID.0000000930
Bolisetty Subhashini, Navjot Pabla
{"title":"The Selenium Heist: Uremic Toxins Orchestrate Kidney Ferroptotic Stress in CKD.","authors":"Bolisetty Subhashini, Navjot Pabla","doi":"10.34067/KID.0000000930","DOIUrl":"10.34067/KID.0000000930","url":null,"abstract":"","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":"6 9","pages":"1427-1429"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12483042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intradialytic Parenteral Nutrition during In-Center Hemodialysis of Patients Leads to Increase in Albumin without Compromising Safety: Retrospective Analysis. 在中心血液透析患者的透析内肠外营养导致白蛋白增加而不影响安全性：回顾性分析。
IF 3
Kidney360 Pub Date : 2025-09-01 Epub Date: 2025-04-01 DOI: 10.34067/KID.0000000789
Maiya Slusser-Hogan, Jamie Haight, Lori Gabriel, Mark A Hardy, Karin Hehenberger
{"title":"Intradialytic Parenteral Nutrition during In-Center Hemodialysis of Patients Leads to Increase in Albumin without Compromising Safety: Retrospective Analysis.","authors":"Maiya Slusser-Hogan, Jamie Haight, Lori Gabriel, Mark A Hardy, Karin Hehenberger","doi":"10.34067/KID.0000000789","DOIUrl":"10.34067/KID.0000000789","url":null,"abstract":"","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":" ","pages":"1532-1540"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12483036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: The Effect of Sodium-Glucose Cotransporter 2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists on 24-Hour Urine Parameters: A Retrospective Cohort Study. 修正：钠-葡萄糖共转运蛋白2抑制剂和胰高血糖素样肽-1受体激动剂对24小时尿液参数的影响：一项回顾性队列研究。
IF 3
Kidney360 Pub Date : 2025-09-01 Epub Date: 2025-08-11 DOI: 10.34067/KID.0000000956
Jennifer A Schaub, Mary K Oerline, Joseph J Crivelli, Naim M Maalouf, Sara L Best, John R Asplin, John M Hollingsworth, Vahakn Shahinian, Ryan S Hsi
{"title":"Correction to: The Effect of Sodium-Glucose Cotransporter 2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists on 24-Hour Urine Parameters: A Retrospective Cohort Study.","authors":"Jennifer A Schaub, Mary K Oerline, Joseph J Crivelli, Naim M Maalouf, Sara L Best, John R Asplin, John M Hollingsworth, Vahakn Shahinian, Ryan S Hsi","doi":"10.34067/KID.0000000956","DOIUrl":"10.34067/KID.0000000956","url":null,"abstract":"","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":" ","pages":"1636-1638"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12483035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atrial Fibrillation in Advanced CKD: To Anticoagulate, or Not, and With What? 晚期CKD房颤：抗凝，或不，和什么？
IF 3
Kidney360 Pub Date : 2025-09-01 Epub Date: 2025-09-25 DOI: 10.34067/KID.0000000869
Muhammad S Ajmal, Wolfgang C Winkelmayer
{"title":"Atrial Fibrillation in Advanced CKD: To Anticoagulate, or Not, and With What?","authors":"Muhammad S Ajmal, Wolfgang C Winkelmayer","doi":"10.34067/KID.0000000869","DOIUrl":"10.34067/KID.0000000869","url":null,"abstract":"","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":"6 9","pages":"1435-1437"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12483049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Different Definitions of Erythropoiesis-Stimulating Agent Hyporesponsiveness with Major Adverse Cardiovascular Events: Insights from ASCEND-D. 不同定义的促红细胞生成剂低反应性与主要心血管不良事件的关联：来自ASCEND-D的见解
IF 3
Kidney360 Pub Date : 2025-09-01 Epub Date: 2025-05-07 DOI: 10.34067/KID.0000000808
Finnian R McCausland, Sushrut S Waikar, Brian Claggett, Gearoid M McMahon, Osvaldo M V Neto, Anjay Rastogi, Kearkiat Praditpornsilpa, Ricardo Correa-Rotter, Vijay Kher, Lucia Del Vecchio, Scott D Solomon, Ajay K Singh
{"title":"Association of Different Definitions of Erythropoiesis-Stimulating Agent Hyporesponsiveness with Major Adverse Cardiovascular Events: Insights from ASCEND-D.","authors":"Finnian R McCausland, Sushrut S Waikar, Brian Claggett, Gearoid M McMahon, Osvaldo M V Neto, Anjay Rastogi, Kearkiat Praditpornsilpa, Ricardo Correa-Rotter, Vijay Kher, Lucia Del Vecchio, Scott D Solomon, Ajay K Singh","doi":"10.34067/KID.0000000808","DOIUrl":"10.34067/KID.0000000808","url":null,"abstract":"","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":" ","pages":"1541-1548"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12483048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypercalcemia in a Patient with CKD Undergoing Left Total Hip Arthroplasty. CKD左全髋关节置换术患者的高钙血症。
IF 3
Kidney360 Pub Date : 2025-09-01 Epub Date: 2025-09-25 DOI: 10.34067/KID.0000000794
Saud Alsaleh, Trevor Stevens, William Fissell
{"title":"Hypercalcemia in a Patient with CKD Undergoing Left Total Hip Arthroplasty.","authors":"Saud Alsaleh, Trevor Stevens, William Fissell","doi":"10.34067/KID.0000000794","DOIUrl":"10.34067/KID.0000000794","url":null,"abstract":"","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":"6 9","pages":"1632-1633"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12483055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Indoxyl Sulfate Contributes to Selenium Deficiency and Renal Ferroptosis by Decreasing the Expression of Selenium Transport Protein Selenoprotein P. 硫酸吲哚酚通过降低硒转运蛋白SEPP1的表达参与硒缺乏和肾铁下沉。
IF 3
Kidney360 Pub Date : 2025-09-01 Epub Date: 2025-05-22 DOI: 10.34067/KID.0000000837
Takehiro Nakano, Yutaka Kitazato, Takumu Ogawa, Kai Tokumaru, Yuhi Shintani, Takuma Yoshitake, Kohei Yasuno, Hitoshi Maeda, Motoko Tanaka, Kazutaka Matsushita, Toru Maruyama, Hiroshi Watanabe
{"title":"Indoxyl Sulfate Contributes to Selenium Deficiency and Renal Ferroptosis by Decreasing the Expression of Selenium Transport Protein Selenoprotein P.","authors":"Takehiro Nakano, Yutaka Kitazato, Takumu Ogawa, Kai Tokumaru, Yuhi Shintani, Takuma Yoshitake, Kohei Yasuno, Hitoshi Maeda, Motoko Tanaka, Kazutaka Matsushita, Toru Maruyama, Hiroshi Watanabe","doi":"10.34067/KID.0000000837","DOIUrl":"10.34067/KID.0000000837","url":null,"abstract":"","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":" ","pages":"1448-1461"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12483056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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