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Renal Disease and Kidney Transplantation in Hispanic American Persons. 西班牙裔美国人的肾病和肾移植。
IF 3.2
Kidney360 Pub Date : 2024-11-01 Epub Date: 2024-09-16 DOI: 10.34067/KID.0000000579
Girish K Mour, Aleksandra Kukla, Andres Jaramillo, Daniel S Ramon, Hani M Wadei, Mark D Stegall
{"title":"Renal Disease and Kidney Transplantation in Hispanic American Persons.","authors":"Girish K Mour, Aleksandra Kukla, Andres Jaramillo, Daniel S Ramon, Hani M Wadei, Mark D Stegall","doi":"10.34067/KID.0000000579","DOIUrl":"10.34067/KID.0000000579","url":null,"abstract":"<p><p>The Hispanic population of the United States is the second largest racial or ethnic group, comprising 18.7% of the population. However, this population is incredibly heterogeneous differing in genetic traits, cultural upbringing, educational backgrounds, and financial status. The impact of this heterogeneity on the prevalence and outcomes of renal disease and kidney transplantation is understudied compared with non-Hispanic White and Black populations. What is known appears to be underrecognized. This review aims to critically assess current medical literature on Hispanic individuals, focusing on etiological factors, disease progression, and outcomes related to CKD and kidney transplantation. By doing so, we aim to underscore key areas for further in-depth investigation.</p>","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":" ","pages":"1763-1770"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142290225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Activation of PIEZO1 Attenuates Kidney Cystogenesis In Vitro and Ex Vivo. 激活 PIEZO1 可减轻体外和体内肾脏囊肿的发生
IF 3.2
Kidney360 Pub Date : 2024-11-01 Epub Date: 2024-10-02 DOI: 10.34067/KID.0000000598
Qingfeng Fan, Mohamad Hadla, Zack Peterson, Grace Nelson, Hong Ye, Xiaofang Wang, Jean Marc Mardirossian, Peter C Harris, Seth L Alper, Y S Prakash, Arthur Beyder, Vicente E Torres, Fouad T Chebib
{"title":"Activation of PIEZO1 Attenuates Kidney Cystogenesis In Vitro and Ex Vivo.","authors":"Qingfeng Fan, Mohamad Hadla, Zack Peterson, Grace Nelson, Hong Ye, Xiaofang Wang, Jean Marc Mardirossian, Peter C Harris, Seth L Alper, Y S Prakash, Arthur Beyder, Vicente E Torres, Fouad T Chebib","doi":"10.34067/KID.0000000598","DOIUrl":"10.34067/KID.0000000598","url":null,"abstract":"","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":" ","pages":"1601-1612"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sodium-Glucose Cotransporter-2 Inhibitors versus Glucagon-Like Peptide 1 Receptor Agonists Effects on Kidney and Clinical Outcomes in Veterans with Type 2 Diabetes. SGLT-2 抑制剂与 GLP-1 受体激动剂对 2 型糖尿病退伍军人肾脏和临床结果的影响。
IF 3.2
Kidney360 Pub Date : 2024-11-01 Epub Date: 2024-10-03 DOI: 10.34067/KID.0000000597
Candis M Morello, Linda Awdishu, Stepfanie Lam, Amy Heman, Mark Bounthavong
{"title":"Sodium-Glucose Cotransporter-2 Inhibitors versus Glucagon-Like Peptide 1 Receptor Agonists Effects on Kidney and Clinical Outcomes in Veterans with Type 2 Diabetes.","authors":"Candis M Morello, Linda Awdishu, Stepfanie Lam, Amy Heman, Mark Bounthavong","doi":"10.34067/KID.0000000597","DOIUrl":"10.34067/KID.0000000597","url":null,"abstract":"","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":" ","pages":"1633-1643"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142372221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Championing the Dialysis Patient Voice: How has the US Legislation Fared? 支持透析患者的声音：美国的立法情况如何？
IF 3.2
Kidney360 Pub Date : 2024-11-01 Epub Date: 2024-08-21 DOI: 10.34067/KID.0000000000000560
Osama El Shamy
{"title":"Championing the Dialysis Patient Voice: How has the US Legislation Fared?","authors":"Osama El Shamy","doi":"10.34067/KID.0000000000000560","DOIUrl":"10.34067/KID.0000000000000560","url":null,"abstract":"","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":" ","pages":"1744-1746"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global Perspective of Acute Kidney Injury: Nigeria. 急性肾损伤的全球视角：尼日利亚。
IF 3.2
Kidney360 Pub Date : 2024-11-01 Epub Date: 2024-09-11 DOI: 10.34067/KID.0000000575
Ugochi Chika Onu, Bala Waziri, Ngozi Rita Mbanefo
{"title":"Global Perspective of Acute Kidney Injury: Nigeria.","authors":"Ugochi Chika Onu, Bala Waziri, Ngozi Rita Mbanefo","doi":"10.34067/KID.0000000575","DOIUrl":"10.34067/KID.0000000575","url":null,"abstract":"","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":" ","pages":"1741-1743"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142290222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Origins and Molecular Mechanisms Underlying Renal Vascular Development. 肾血管发育的起源和分子机制。
IF 3.2
Kidney360 Pub Date : 2024-11-01 Epub Date: 2024-08-08 DOI: 10.34067/KID.0000000000000543
Yusuke Nishimura, Sanshiro Hanada
{"title":"Origins and Molecular Mechanisms Underlying Renal Vascular Development.","authors":"Yusuke Nishimura, Sanshiro Hanada","doi":"10.34067/KID.0000000000000543","DOIUrl":"10.34067/KID.0000000000000543","url":null,"abstract":"<p><p>Kidneys play a crucial role in maintaining homeostasis within the body, and this function is intricately linked to the vascular structures within them. For vascular cells in the kidney to mature and function effectively, a well-coordinated spatial alignment between the nephrons and complex network of blood vessels is essential. This arrangement ensures efficient blood filtration and regulation of the electrolyte balance, blood pressure, and fluid levels. Additionally, the kidneys are vital in regulating the acid-base balance and producing hormones involved in erythropoiesis and blood pressure control. This article focuses on the vascular development of the kidneys, summarizing the current understanding of the origin and formation of the renal vasculature, and the key molecules involved. A comprehensive review of existing studies has been conducted to elucidate the cellular and molecular mechanisms governing renal vascular development. Specific molecules play a critical role in the development of renal vasculature, contributing to the spatial alignment between nephrons and blood vessels. By elucidating the cellular and molecular mechanisms involved in renal vascular development, this study aims to advance renal regenerative medicine and offer potential avenues for therapeutic interventions in kidney disease.</p>","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":" ","pages":"1718-1726"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141906966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Kidney Injury Associated with Anticancer Therapies: Small Molecules and Targeted Therapies. 与抗癌疗法相关的 AKI：小分子和靶向治疗。
IF 3.2
Kidney360 Pub Date : 2024-11-01 Epub Date: 2024-08-26 DOI: 10.34067/KID.0000000566
Jaya Kala, Teresa Joseph, Marta Pirovano, Roberta Fenoglio, Laura Cosmai
{"title":"Acute Kidney Injury Associated with Anticancer Therapies: Small Molecules and Targeted Therapies.","authors":"Jaya Kala, Teresa Joseph, Marta Pirovano, Roberta Fenoglio, Laura Cosmai","doi":"10.34067/KID.0000000566","DOIUrl":"10.34067/KID.0000000566","url":null,"abstract":"<p><p>Molecular targeted therapy has revolutionized cancer treatment by significantly improving patient survival compared with standard conventional chemotherapies. The use of these drugs targets specific molecules or targets, which block growth and spread of cancer cells. Many of these therapies have been approved for use with remarkable success in breast, blood, colorectal, lung, and ovarian cancers. The advantage over conventional chemotherapy is its ability to deliver drugs effectively with high specificity while being less toxic. Although known as \"targeted,\" many of these agents lack specificity and selectivity, and they tend to inhibit multiple targets, including those in the kidneys. The side effects usually arise because of dysregulation of targets of the inhibited molecule in normal tissue. The off-target effects are caused by drug binding to unintended targets. The on-target effects are associated with inhibition toward the pathway reflecting inappropriate inhibition or activation of the intended drug target. Early detection and correct management of kidney toxicities is crucial to preserve kidney functions. The knowledge of these toxicities helps guide optimal and continued utilization of these potent therapies. This review summarizes the different types of molecular targeted therapies used in the treatment of cancer and the incidence, severity, and pattern of nephrotoxicity caused by them, with their plausible mechanism and proposed treatment recommendations.</p>","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":" ","pages":"1750-1762"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142073201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Social Deprivation Index with Home Dialysis Technique Failure: A Single-Center Experience. 社会贫困指数与家庭透析技术失败的关系：单中心经验。
IF 3.2
Kidney360 Pub Date : 2024-11-01 Epub Date: 2024-08-23 DOI: 10.34067/KID.0000000000000557
Justin Weissberg, Catherine Liu, TramAnh Phan, Scott Liebman, Sai Subhodhini Reddy, Catherine A Moore
{"title":"Association of Social Deprivation Index with Home Dialysis Technique Failure: A Single-Center Experience.","authors":"Justin Weissberg, Catherine Liu, TramAnh Phan, Scott Liebman, Sai Subhodhini Reddy, Catherine A Moore","doi":"10.34067/KID.0000000000000557","DOIUrl":"10.34067/KID.0000000000000557","url":null,"abstract":"","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":" ","pages":"1644-1651"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142044039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety and Efficacy of Vadadustat Once Daily and Three Times Weekly in Patients With Dialysis-Dependent CKD With Anemia. 每日一次和每周三次服用伐杜司他治疗透析依赖型慢性肾病贫血患者的安全性和有效性
IF 3.2
Kidney360 Pub Date : 2024-11-01 Epub Date: 2024-09-04 DOI: 10.34067/KID.0000000567
Laura Kooienga, Steven Burke, Amarnath Kathresal, Wenli Luo, Zhihui Yang, Zhiqun Zhang, Rafal Zwiech, German T Hernandez
{"title":"Safety and Efficacy of Vadadustat Once Daily and Three Times Weekly in Patients With Dialysis-Dependent CKD With Anemia.","authors":"Laura Kooienga, Steven Burke, Amarnath Kathresal, Wenli Luo, Zhihui Yang, Zhiqun Zhang, Rafal Zwiech, German T Hernandez","doi":"10.34067/KID.0000000567","DOIUrl":"10.34067/KID.0000000567","url":null,"abstract":"","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":" ","pages":"1652-1661"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in 24-Hour Urine Chemistry in Patients with Nephrolithiasis during Weight Loss with Glucagon-Like Peptide 1-Based Therapies. 肾炎患者在使用胰高血糖素样肽-1疗法减肥期间 24 小时尿液化学成分的变化
IF 3.2
Kidney360 Pub Date : 2024-11-01 Epub Date: 2024-09-18 DOI: 10.34067/KID.0000000580
Karen Feghali, Xilong Li, Naim M Maalouf
{"title":"Changes in 24-Hour Urine Chemistry in Patients with Nephrolithiasis during Weight Loss with Glucagon-Like Peptide 1-Based Therapies.","authors":"Karen Feghali, Xilong Li, Naim M Maalouf","doi":"10.34067/KID.0000000580","DOIUrl":"10.34067/KID.0000000580","url":null,"abstract":"","PeriodicalId":17882,"journal":{"name":"Kidney360","volume":" ","pages":"1706-1712"},"PeriodicalIF":3.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142290221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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