Jiahui Zhang, Lili Xu, Gumuyang Zhang, Daming Zhang, Xiaoxiao Zhang, Xin Bai, Li Chen, Qianyu Peng, Zhengyu Jin, Hao Sun
{"title":"Multiparametric MRI to Predict Gleason Score Upgrading and Downgrading at Radical Prostatectomy Compared to Presurgical Biopsy.","authors":"Jiahui Zhang, Lili Xu, Gumuyang Zhang, Daming Zhang, Xiaoxiao Zhang, Xin Bai, Li Chen, Qianyu Peng, Zhengyu Jin, Hao Sun","doi":"10.3348/kjr.2024.1008","DOIUrl":"10.3348/kjr.2024.1008","url":null,"abstract":"<p><strong>Objective: </strong>This study investigated the value of multiparametric MRI (mpMRI) in predicting Gleason score (GS) upgrading and downgrading in radical prostatectomy (RP) compared with presurgical biopsy.</p><p><strong>Materials and methods: </strong>Clinical and mpMRI data were retrospectively collected from 219 patients with prostate disease between January 2015 and December 2021. All patients underwent systematic prostate biopsy followed by RP. MpMRI included conventional diffusion-weighted and dynamic contrast-enhanced imaging. Multivariable logistic regression analysis was performed to analyze the factors associated with GS upgrading and downgrading after RP. Receiver operating characteristic curve analysis was used to estimate the area under the curve (AUC) to indicate the performance of the multivariable logistic regression models in predicting GS upgrade and downgrade after RP.</p><p><strong>Results: </strong>The GS after RP was upgraded, downgraded, and unchanged in 92, 43, and 84 patients, respectively. The AUCs of the clinical (percentage of positive biopsy cores [PBCs], time from biopsy to RP) and mpMRI models (prostate cancer [PCa] location, Prostate Imaging Reporting and Data System [PI-RADS] v2.1 score) for predicting GS upgrading after RP were 0.714 and 0.749, respectively. The AUC of the combined diagnostic model (age, percentage of PBCs, tPSA, PCa location, and PI-RADS v2.1 score) was 0.816, which was larger than that of the clinical factors alone (<i>P</i> < 0.001). The AUCs of the clinical (age, percentage of PBCs, ratio of free/total PSA [F/T]) and mpMRI models (PCa diameter, PCa location, and PI-RADS v2.1 score) for predicting GS downgrading after RP were 0.749 and 0.835, respectively. The AUC of the combined diagnostic model (age, percentage of PBCs, F/T, PCa diameter, PCa location, and PI-RADS v2.1 score) was 0.883, which was larger than that of the clinical factors alone (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Combining clinical factors and mpMRI findings can predict GS upgrade and downgrade after RP more accurately than using clinical factors alone.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":"422-434"},"PeriodicalIF":4.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055267/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Women and the Road to Radiology Leadership: An Asian Perspective.","authors":"Evelyn Lai Ming Ho","doi":"10.3348/kjr.2025.0140","DOIUrl":"https://doi.org/10.3348/kjr.2025.0140","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":"26 5","pages":"397-399"},"PeriodicalIF":4.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"2025 Korean Society of Abdominal Radiology Recommendations on Gallbladder Polyps and Gallbladder Wall Thickening Warrant Further Investigation and Clarification.","authors":"Chen Lin, Liang Zhu","doi":"10.3348/kjr.2025.0201","DOIUrl":"10.3348/kjr.2025.0201","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":"514-515"},"PeriodicalIF":4.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Recommendations for Gallbladder Polyps and Gallbladder Wall Thickening Between KSAR and WFUMB Guidelines.","authors":"Rui Cheng, Yi Dong","doi":"10.3348/kjr.2025.0186","DOIUrl":"10.3348/kjr.2025.0186","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":"508-510"},"PeriodicalIF":4.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lu Qiu, Miaoyan Wang, Surui Liu, Bo Peng, Ying Hua, Jianbiao Wang, Xiaoyue Hu, Anqi Qiu, Yakang Dai, Haoxiang Jiang
{"title":"Multi-Parameter MRI for Evaluating Glymphatic Impairment and White-Matter Abnormalities and Discriminating Refractory Epilepsy in Children.","authors":"Lu Qiu, Miaoyan Wang, Surui Liu, Bo Peng, Ying Hua, Jianbiao Wang, Xiaoyue Hu, Anqi Qiu, Yakang Dai, Haoxiang Jiang","doi":"10.3348/kjr.2024.0718","DOIUrl":"10.3348/kjr.2024.0718","url":null,"abstract":"<p><strong>Objective: </strong>To explore glymphatic impairment in pediatric refractory epilepsy (RE) using multi-parameter magnetic resonance imaging (MRI), assess its relationship with white-matter (WM) abnormalities and clinical indicators, and preliminarily evaluate the performance of multi-parameter MRI in discriminating RE from drug-sensitive epilepsy (DSE).</p><p><strong>Materials and methods: </strong>We retrospectively included 70 patients with DSE (mean age, 9.7 ± 3.5 years; male:female, 37:33) and 26 patients with RE (9.0 ± 2.9 years; male:female, 12:14). The diffusion tensor imaging analysis along the perivascular space (DTI-ALPS) index as well as fractional anisotropy (FA), mean diffusivity (MD), and nodal efficiency values were measured and compared between patients with RE and DSE. With sex and age as covariables, differences in the FA and MD values were analyzed using tract-based spatial statistics, and nodal efficiency was analyzed using a linear model. Pearson's partial correlation was analyzed. Receiver operating characteristic (ROC) curves were used to evaluate the discrimination performance of the MRI-based machine-learning models through five-fold cross-validation.</p><p><strong>Results: </strong>In the RE group, FA decreased and MD increased in comparison with the corresponding values in the DSE group, and these differences mainly involved the callosum, right and left corona radiata, inferior and superior longitudinal fasciculus, and posterior thalamic radiation (threshold-free cluster enhancement, <i>P</i> < 0.05). The RE group also showed reduced nodal efficiency, which mainly involved the limbic system, default mode network, and visual network (false discovery rate, <i>P</i> < 0.05), and significantly lower DTI-ALPS index (F = 2.0, <i>P</i> = 0.049). The DTI-ALPS index was positively correlated with FA (0.25 ≤ <i>r</i> ≤ 0.32) and nodal efficiency (0.22 ≤ <i>r</i> ≤ 0.37), and was negatively correlated with the MD (-0.24 ≤ <i>r</i> ≤ -0.34) and seizure frequency (<i>r</i> = -0.47). A machine-learning model combining DTI-ALPS, FA, MD, and nodal efficiency achieved a cross-validated ROC curve area of 0.83 (sensitivity, 78.2%; specificity, 84.8%).</p><p><strong>Conclusion: </strong>Pediatric patients with RE showed impaired glymphatic function in comparison with patients with DSE, which was correlated with WM abnormalities and seizure frequency. Multi-parameter MRI may be feasible for distinguishing RE from DSE.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":"26 5","pages":"485-497"},"PeriodicalIF":5.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peipei Li, Chengli Li, Yujun Xu, Xiangmeng He, Roberto Blanco Sequeiros, Ming Liu
{"title":"Feasibility of Multiparameter MRI-Guided Percutaneous Biopsy for Central Lung Lesions With Atelectasis.","authors":"Peipei Li, Chengli Li, Yujun Xu, Xiangmeng He, Roberto Blanco Sequeiros, Ming Liu","doi":"10.3348/kjr.2024.0818","DOIUrl":"https://doi.org/10.3348/kjr.2024.0818","url":null,"abstract":"<p><strong>Objective: </strong>To prospectively evaluate the feasibility, accuracy, and safety of multiparameter MRI-guided percutaneous biopsy using a 1T open MRI scanner for evaluating suspicious centrally located lung lesions with associated post-obstructive atelectasis.</p><p><strong>Materials and methods: </strong>In this single-center study, MRI-guided percutaneous coaxial cutting biopsy was performed for 107 suspicious central lung lesions with associated post-obstructive atelectasis in 107 patients between July 2015 and December 2020. A fast T2-weighted imaging (T2WI)-turbo spin echo (TSE) sequence and an enhanced fast T1-weighted imaging (T1WI)-TSE sequence were used to identify, localize, and biopsy lung lesions, and diffusion-weighted imaging (DWI) was used as a supplementary sequence for identifying the lesion location. The final diagnosis was confirmed by surgical histopathology or clinical follow-up for a minimum of 24 months. The sensitivity, specificity, and accuracy for diagnosing lung malignancies were calculated, and the complications were recorded for each case.</p><p><strong>Results: </strong>Using multiparameter MRI, central lung lesions could be clearly distinguished from post-obstructive atelectasis in 96 patients (89.7%). The sensitivity, specificity, and accuracy of MRI-guided percutaneous biopsy for diagnosing lung malignancy was 97.0% (98/101), 100% (6/6), and 97.2% (104/107), respectively. Self-limited hemoptysis occurred in three patients. Pneumothorax occurred in five patients, of which none required pleural drainage. No serious procedure-related complications were observed.</p><p><strong>Conclusion: </strong>As a technology that does not involve ionizing radiation, multiparameter MRI-guided percutaneous coaxial cutting biopsy is a safe and accurate diagnostic technique for evaluating centrally located lung lesions associated with post-obstructive atelectasis.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":"26 5","pages":"498-507"},"PeriodicalIF":4.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144007579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Safety and Efficacy of Radiofrequency Ablation for Superficial Parotid Pleomorphic Adenoma.","authors":"Chih-Ying Lee, Wei-Che Lin, Sheng-Dean Luo, Pi-Ling Chiang, An-Ni Lin, Cheng-Kang Wang, Chun-Yuan Chao","doi":"10.3348/kjr.2024.0909","DOIUrl":"https://doi.org/10.3348/kjr.2024.0909","url":null,"abstract":"<p><strong>Objective: </strong>To retrospectively compare the safety and efficacy of ultrasound-guided radiofrequency ablation (RFA) with parotidectomy for superficial pleomorphic adenoma (PA).</p><p><strong>Materials and methods: </strong>From March 2022 to October 2023, 88 patients diagnosed with superficial parotid PA underwent either RFA (n = 12; mean age, 47.1 years) or parotidectomy (n = 76; mean age, 47.8 years). Patients in the RFA group were matched to those in the surgery group in a 1:1 ratio using propensity scores based on age, sex, tumor volume, diameter, location, and comorbidities. Ultrasound characteristics, cosmetic scores (0-4), numerical rating scale scores (0-10), and complications were assessed before the procedures and at 1-, 3-, and 6-month follow-ups. Outcomes were compared between baseline and follow-up in the RFA group and between the RFA and surgery groups.</p><p><strong>Results: </strong>In the RFA group, significant reductions in tumor volume were observed between baseline (median, 2.02 cm³) and the 1-month follow-up (median, 1.21 cm³; <i>P</i> = 0.015), between the 1-month and 3-month follow-ups (median, 0.53 cm³; <i>P</i> = 0.002), and between the 3- and 6-month follow-ups (median, 0.23 cm³; <i>P</i> = 0.003). The volume reduction ratios at 1, 3, and 6 months were 39.7%, 79.9%, and 88.0%, respectively. The cosmetic score was significantly lower at 3- and 6-month follow-up compared to baseline (median 1 and 1 vs. 4, <i>P</i> = 0.04). The numerical rating scale scores did not differ significantly from baseline throughout follow-up. In the propensity score-matched analysis (12 patients per group), RFA was associated with a shorter median procedure time (61.5 vs. 253.3 minutes; <i>P</i> < 0.001), shorter hospital stay (0 vs. 4 days; <i>P</i> < 0.001), and lower cost (1859.9 vs. 3512.4 USD; <i>P</i> < 0.001) than parotidectomy, with no significant difference in overall complication rates (33.3% [4/12] vs. 41.7% [5/12]; <i>P</i> = 1.000).</p><p><strong>Conclusion: </strong>RFA may be a safe and effective alternative to surgery for superficial parotid PA, offering a shorter median procedure time, shorter hospital stay, and lower costs.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":"26 5","pages":"460-470"},"PeriodicalIF":4.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to \"Artificial Intelligence Combined With Chest Radiography: New Hope for the Opportunistic Screening for Osteoporosis\".","authors":"Chiao-Lin Hsu, Hon-Yi Shi","doi":"10.3348/kjr.2025.0102","DOIUrl":"10.3348/kjr.2025.0102","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":"392-393"},"PeriodicalIF":4.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dong Jun Kim, Nan-He Yoon, Jae Kwan Jun, Mina Suh, Sunhwa Lee, Seongju Kim, Horim A Hwang, Seung Eun Jung, Hooyeon Lee
{"title":"Biennial Mammography Performance in the Korean National Cancer Screening Program From 2009 to 2020.","authors":"Dong Jun Kim, Nan-He Yoon, Jae Kwan Jun, Mina Suh, Sunhwa Lee, Seongju Kim, Horim A Hwang, Seung Eun Jung, Hooyeon Lee","doi":"10.3348/kjr.2024.0866","DOIUrl":"10.3348/kjr.2024.0866","url":null,"abstract":"<p><strong>Objective: </strong>Mammography is essential for reducing breast cancer mortality; however, its performance varies globally. This study aimed to evaluate mammography screening outcomes in Korea over 12 years and investigate regional variations.</p><p><strong>Materials and methods: </strong>We analyzed mammography data from 42 million Korean women, aged 40 years and older, who participated in the Korean National Cancer Screening Program (KNCSP) from 2009 to 2020. Performance metrics-including recall rate (RR), positive predictive value (PPV), sensitivity, specificity, false positive rate (FPR), cancer detection rate (CDR), interval cancer rate (ICR), and dense breast rate (DBR), were computed. Twelve-year trends in these metrics were analyzed using Joinpoint regression. Regional variations were also examined across Korea's 237 districts, stratified by age groups.</p><p><strong>Results: </strong>From 2009 to 2020, 42165405 mammography screenings were conducted through the KNCSP, increasing from 2821132 screenings in 2009 to 3596204 in 2020. The RR decreased from 17.2% in 2009 to 11.2% in 2020 (average annual percent change [AAPC] = -3.7%), while the PPV increased from 0.8% to 2.8%; AAPC = 10.7%), the CDR increased from 1.5 to 3.1 per 1000; AAPC = 7.3%), and the ICR rose from 0.9 to 1.6 per 1000; (AAPC = 5.2%). Regional variations were noted; however, differences in the RR, sensitivity, specificity, and FPR decreased over time.</p><p><strong>Conclusion: </strong>While mammography performance improved from 2009 to 2020, the PPV and sensitivity remain suboptimal, underscoring the need for continuous monitoring. Regional disparities in performance, although reduced, persist. These findings provide essential baseline data for improving mammography quality and addressing inequities in breast cancer screening.</p>","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":"313-323"},"PeriodicalIF":4.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jei Hee Lee, Ji Seon Park, A Leum Lee, Yun-Jung Lim, Seung Eun Jung
{"title":"Training of Radiology Residents in Korea.","authors":"Jei Hee Lee, Ji Seon Park, A Leum Lee, Yun-Jung Lim, Seung Eun Jung","doi":"10.3348/kjr.2024.1151","DOIUrl":"10.3348/kjr.2024.1151","url":null,"abstract":"","PeriodicalId":17881,"journal":{"name":"Korean Journal of Radiology","volume":" ","pages":"291-293"},"PeriodicalIF":4.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}