JURNAL BIOMEDIK (JBM)最新文献

{"title":"Latihan Fisik Pada Pasien Obesitas","authors":"Pricillia J. Oroh, Herlina I. S. Wungow, J. N. Engka","doi":"10.35790/jbm.13.1.2021.31773","DOIUrl":"https://doi.org/10.35790/jbm.13.1.2021.31773","url":null,"abstract":"Abstract: Increase in cases of obese patients in developed and developing countries is a problem that occurs from year to year. Prevalence rates of obesity cases has increased in the last 5 years. Prevalence rate of obesity in Indonesia is 21.8%. North Sulawesi is the province with the highest obesity in Indonesia. Obesity can cause many health problems, therefore it takes effort by doing regular physical exercise, in order to increase the body metabolism for obese patients. Purpose of this study is to determine the effect/benefit of physical exercise in obese patients. Material and method used is a literature review with five databases, namely, Clinical Key, PubMed, Science Direct, and Indonesian Scientific Repository. Keywords used are physical activity OR physical training OR exercise program OR exercise therapy OR obesity. Study selection stage obtained 20 literature consisting of 19 randomized controlled trials, and 1 experimental study. Results of the literature review study show that all physical exercise provides benefits to the body, but aerobic physical exercise is mostly done in obese patients. Conclusion: Physical exercise in the form of aerobic exercise, anaerobic exercise, and regular resistance training can provide weight loss, and reduce body fat in obese patients.Key words: physical exercise, physical activity, obesity.  Abstrak: Peningkatan kasus pasien obesitas di negara maju, dan negara berkembang merupakan suatu masalah yang terjadi dari tahun ke tahun. Prevalensi kasus obesitas meningkat pada 5 tahun terakhir. Tingkat prevalensi obesitas di Indonesia adalah 21,8%. Sulawesi Utara merupakan provinsi dengan obesitas tertinggi di Indonesia. Obesitas dapat menyebabkan banyak gangguan kesehatan bagi tubuh, maka diperlukan upaya dengan melakukan latihan fisik yang tepat, agar mampu meningkatkan metabolisme tubuh bagi pasien obesitas. Tujuan penelitian adalah untuk mengetahui pengaruh atau manfaat latihan fisik pada pasien obesitas. Materi dan metode penelitian yang digunakan literature review dengan lima database yaitu Clinical Key, PubMed, Science Direct, dan Repositori Ilmiah Indonesia. Kata kunci yang digunakan yaitu physical activity OR physical training OR exercise program OR exercise therapy OR obesity. Tahap seleksi studi didapatkan 20 literatur terdiri dari 19 randomized controlled trial, dan 1 penelitian eksperimental. Hasil penelitian literature review menunjukkan semua latihan fisik memberikan manfaat bagi tubuh, tetapi latihan fisik aerobik paling banyak dilakukan pada pasien obesitas. Kesimpulan: Latihan fisik dalam bentuk latihan aerobik, latihan anaerobik, dan latihan daya tahan yang teratur dapat memberikan penurunan berat badan, dan mengurangi lemak tubuh pada pasien obesitas.Kata kunci:  Latihan fisik, aktifitas fisik, obesitas","PeriodicalId":17726,"journal":{"name":"JURNAL BIOMEDIK (JBM)","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87171343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Korelasi antara Derajat Deviasi Septum Nasi dengan Aerasi Telinga Tengah dan Rongga Mastoid menggunakan Modalitas CT Scan","authors":"Rio Andono, Nikmatia Latief, Nurlaily Idris","doi":"10.35790/jbm.13.1.2021.32183","DOIUrl":"https://doi.org/10.35790/jbm.13.1.2021.32183","url":null,"abstract":"Abstract: Nasal septum deviation can affect the middle ear aeration-mastoid pneumatization system. The aim of this study was to analyze the correlation between the degree of nasal septum deviation with middle ear aeration and mastoid cavity using CT scan. Conducted retrospectively on nasal septum deviation patients who underwent a CT scan of paranasal sinuses at the central radiology department of  UNHAS, Makassar for the period of January 2018 to September 2020. Samples were as many as 48 patients aged >18 years who had diagnosed nasal septum deviation. The degree of nasal septum deviation is divided into mild (<9°), moderate (9-15°) and severe (>15°). The statistical method used was the Spearman correlation test. There was significant correlation between the degree of nasal septum deviation with ipsilateral tympanic membrane retraction with a p value 0,001 and ipsilateral mastoid pneumatization with a p value of 0.03 (<0,05). The results of this study indicate that there is significant correlation between the degree of nasal septum deviation with ipsilateral tympanic membrane retraction  and ipsilateral mastoid pneumatization. There is a correlation between moderate and severe nasal septum deviation with ipsilateral middle ear effusion, where the deviation degree of the nasal septum is getting increased, then there is a tendency for an increase in ipsilateral middle ear effusion compared to contralateral side.Keywords: Degree of nasal septum deviation, middle ear effusion, tympanic membrane retraction, mastoid pneumatization, CT Scan Abstrak: Deviasi septum nasi dapat mempengaruhi tekanan telinga tengah-sistem pneumatisasi mastoid. Tujuan penelitian ini adalah untuk menganalisis korelasi antara derajat deviasi septum nasi dengan aerasi telinga tengah dan rongga mastoid menggunakan modalitas CT-scan. Dilakukan secara retrospektif pada penderita deviasi septum nasi yang menjalani pemeriksaan CT-scan sinus paranasalis di instalasi radiologi sentral RS UNHAS, Makassar periode Januari 2018 sampai September 2020. Sampel sebanyak 48 orang dengan usia >18 tahun yang didiagnosis deviasi septum nasi. Derajat deviasi septum nasi dibagi menjadi ringan (<9°), sedang (9°-15°), dan berat (>15°) Metode statistik yang digunakan uji korelasi Spearman. Terdapat korelasi yang bermakna antara derajat deviasi septum nasi dengan retraksi membran timpani ipsilateral 0,001 dan pneumatisasi mastoid ipsilateral 0,03 (<0,05). Hasil penelitian ini menunjukkan terdapat korelasi yang bermakna antara derajat deviasi septum nasi dengan retraksi membran timpani ipsilateral dan pneumatisasi mastoid ipsilateral. Terdapat korelasi antara deviasi septum nasi derajat sedang dan berat dengan efusi telinga tengah ipsilateral, dimana semakin bertambah derajat deviasi septum nasi maka ada kecenderungan peningkatan efusi telinga tengah ipsilateral dibandingkan kontralateral.Kata kunci: Derajat deviasi septum nasi, efusi telinga tengah, retraksi membran timpani, pneumatisasi mastoid, CT S","PeriodicalId":17726,"journal":{"name":"JURNAL BIOMEDIK (JBM)","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72941961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Luaran Maternal dan Perinatal pada Preeklampsia Berat dan Eklampsia","authors":"Anastasia M. Lumentut, Hermie M. M. Tendean","doi":"10.35790/jbm.13.1.2021.32109","DOIUrl":"https://doi.org/10.35790/jbm.13.1.2021.32109","url":null,"abstract":"Abstract: Preeclampsia and  eclampsia are a complication in pregnancy which can increase the maternal and neonatal morbidity and mortality in Indonesia. This study aimed to illustrate outcome severe preeclampsia and eclampsia at RSUP Prof. Dr. R. D. Kandou Manado on period January 1st – December 31st, 2018. Design of study is descriptive retrospective method. The results of study, in the period from January 1st – December 31st, 2018 at RSUP Prof. Dr. R. D. Kandou Manado there are 1366 deliveries which 322 cases (23.57%) severe preeclampsia and 12 cases (0.88%) eclampsia. For severe preeclampsia obtained maternal age ≥ 35 years as much as 128 cases (39.8%), gestational age 37–40 weeks as much as 186 cases (56.3%), cesarean section delivery as much as 214 cases (66.5%), appropriate gestational age as much as 257 cases (79.8%), APGAR Score 4-6 as much as 165 cases (64.3%), perinatal mortality as much as 8 cases (6.08o/oo). For eclampsia obtained maternal age between 21-29 years as much as 5 cases (41.6%), gestational age < 37 weeks as much as 7 cases (58.3%), cesarean section delivery as much as 12 cases (100%), small gestational age as much as 9 cases (75%), maternal mortality as much as 8 cases (5.95%o), perinatal mortality as much as 2 cases (1.52o/oo). In conclusion, outcomes of severe preeclampsia and eclampsia obtained in accordance  with the literature where APGAR Score babies are not very good so it affects the rate of perinatal mortality. Perinatal mortality caused by intrauterine hypoxia and prematurity.Key Words: severe preeclampsia, eclampsia, maternal mortality, perinatal mortality  Abstrak: Preeklampsia dan eklampsia merupakan komplikasi kehamilan yang dapat meningkatkan morbiditas dan mortalitas maternal maupun perinatal di Indonesia. Tujuan penelitian utuk mengetahui luaran maternal dan perinatal pada preeklampsia berat dan eklampsia di RSUP Prof. Dr. R. D. Kandou Manado periode 1 Januari– 31 Desember 2018. Penelitian menggunakan metode deskriptif retrospektif. Hasil penelitian, pada periode 1 Januari - 31 Desember 2018 di RSUP Prof. Dr. R. D. Kandou Manado terdapat 1366 persalinan diantaranya 322 kasus (23.57%) preeklampsia berat dan 12 kasus (0.88%) eklampsia. Untuk preeklampsia berat didapatkan usia ≥ 35 tahun sebanyak 128 kasus (39.8%), kehamilan 37–40 minggu sebanyak 186 kasus (56.3%), persalinan seksio sesarea sebanyak 214 kasus (66.5%), berat badan bayi sesuai masa kehamilan sebanyak 257 kasus (79.8%), nilai APGAR 4–6 sebanyak 165 kasus (64.3%) dan kematian perinatal sebanyak 8 kasus (6.08o/oo). Untuk eklampsia didapatkan pada usia 21-29 tahun sebanyak 5 kasus (55.6%), kehamilan < 37 minggu sebanyak 6 kasus (66.7%), persalinan seksio sesarea sebanyak 12 kasus (100%), berat badan bayi kecil masa kehamilan sebanyak 9 kasus (75%), kematian maternal sebanyak 8 kasus (5.95%o), kematian perinatal sebanyak 2 kasus (1.52o/oo). Sebagai simpulan, hasil luaran preeklampsia berat dan eklampsia sesuai dengan kepustakaan bahwa nilai APGAR b","PeriodicalId":17726,"journal":{"name":"JURNAL BIOMEDIK (JBM)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79515941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hubungan Antara Parameter Geometrik Sagital Lumbosakral Dengan Kejadian Hernia Nukleus Pulposus Pada Pasien Yang Dilakukan Pemeriksaan MRI Lumbosakral","authors":"Martin L. Simanjuntak, Muhammad Ilyas, Bachtiar Murtala, Alfi Zainuddin","doi":"10.35790/jbm.13.1.2021.32080","DOIUrl":"https://doi.org/10.35790/jbm.13.1.2021.32080","url":null,"abstract":"Abstract: The research aimed at analyzing the relationship between the lumbosacral sagittal geometric parameter and the herniated nucleus pulposus incident in the patients undergoing the lumbosacral MRI examination. The research was conducted in the Radiological Installation of Doctor Wahidin Sudirohusodo Hospital, Makassar from February to April 2020. Samples were as many as 65 patients. The data were analyzed using Spearman's correlation and Chi-square tests. The research result indicates that there is the significant relationship between the global lumbosacral angle (p=0.020, r=0.287), sacral table angle (p=0.018, r=0.292), lumbar sagittal balance axis (p=0.011, r=0.313), age (p=0.004, r=0.354) and the herniated nucleus pulposus incident. The smaller the global lumbosacral angle, the higher the herniated nucleus pulposus degree. The greater the sacral table angle and lumbar sagittal balance axis, the higher the herniated nucleus pulposus degree. The greater the age (old), the higher the herniated nucleus pulposus degree. There is no significant relationship between the sacral kyphosis angle (p=0.127), sex (p=0.717), body mass index (p=0.220) and the herniated nucleus pulposus incident. However, there is the tendency that the smaller the sacral kyphosis angle, the higher the herniated nucleus pulposus degree. There is also the tendency that the greater the body mass index, the higher the herniated nucleus pulposus degree.Key words: Global lumbosacral angle, sacral table angle, sacral kyphosis angle, lumbar sagittal balance axis, age, sex, body mass index, herniated nucleus pulposus Abstrak: Penelitian ini bertujuan menganalisis hubungan antara parameter geometrik sagital lumbosakral dengan kejadian hernia nukleus pulposus pada pasien yang dilakukan pemeriksaan MRI lumbosakral. Penelitian ini dilaksanakan di Instalasi Radiologi Rumah Sakit Dokter Wahidin Sudirohusodo Makassar mulai bulan Februari sampai dengan bulan April 2020. Jumlah sampel sebanyak 65 pasien. Metode yang digunakan adalah Uji korelasi Spearman dan Chi Square. Hasil penelitian menunjukkan ada hubungan yang bermakna antara sudut global lumbosacral (p=0,020, r=-0,287), sudut sacral table (p=0,018, r=0,292), lumbar sagittal balance axis (p=0,011, r=0,313), umur (p=0,004, r=0,354) dengan kejadian hernia nukleus pulposus. Semakin kecil sudut global lumbosacral maka semakin tinggi derajat hernia nukleus pulposus. Semakin besar sudut sacral table dan lumbar sagittal balance axis maka semakin tinggi derajat hernia nukleus pulposus. Semakin bertambah umur (tua) maka semakin tinggi derajat hernia nukleus pulposus. Tidak ada hubungan yang bermakna antara sudut sacral kyphosis (p=0,127), jenis kelamin (p=0,717), indeks massa tubuh (p=0,220) dengan kejadian hernia nukleus pulposus. Namun, terlihat kecenderungan bahwa semakin kecil sudut sacral kyphosis maka semakin tinggi derajat hernia nukleus pulposus. Terlihat juga kecenderungan bahwa semakin besar indeks massa tubuh maka semakin tinggi d","PeriodicalId":17726,"journal":{"name":"JURNAL BIOMEDIK (JBM)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76163630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hubungan Kadar Interleukin 6 dan Interleukin 10 Serum pada Pasien Cedera Otak Berat Akibat Trauma","authors":"Rustandy Natsir, E. Prasetyo, M. C. Oley, F. Langi","doi":"10.35790/jbm.13.1.2021.32475","DOIUrl":"https://doi.org/10.35790/jbm.13.1.2021.32475","url":null,"abstract":"Abstract: The elevated of serum interleukin-6 (IL-6) and interleukin-10 (IL-10) levels in patients with traumatic brain injury (TBI) have been documented. The correlation between levels of serum IL-6 and IL-10 in the early phase could provide an assessment of prognosis and outcome in patients with severe TBI. This study was aimed to obtain the correlation of levels of IL-6 and IL-10 serum in severe TBI patients. This was an observational and analytical study with a cross sectional design. Venous blood samples for serum IL-6 and IL-10 were taken less than 24 hours post injury. Age and sex were recorded and variable selection was carried out gradually. A proportional regression model was used to assess the correlation between IL-6 and IL-10 serum levels. The results showed that there were 20 patients with severe TBI admitted to the Emergency Room. The mean IL-6 serum level was 22.0 pg/mL (SD±4.6 pg/mL) and the mean IL-10 serum level was 105.7 pg/mL (SD±16.7 pg/mL). The levels of the two biomarkers were not significantly different among men and women in the population study. The Pearson correlation test resulted in an r value of 0.46 and a p value of 0.041. The results of the regression modelling presented that increased IL-6 serum level was followed by increased IL-10 serum level of nearly 2 pg/mL (p=0.041). After controlling variations in other variables, the regression coefficient value for this correlation increased up to nearly 3 pg/mL (p=0.001). In conclusion, there is a correlation between the serum level of IL- 6 and IL-10 in patients with severe TBI.Keywords: interleukin 6 (IL-6), interleukin 10 (IL-10), severe traumatic brain injury (TBI) Abstrak: Peningkatan kadar interleukin 6 (IL-6) dan interleukin (IL-10) serum pada pasien dengan cedera otak akibat trauma (COT) telah didokumentasikan. Namun, hubungan tingkat keparahan dan mortalitas antara IL-6 dan IL-10 pada fase awal trauma masih perlu diteliti untuk mendapatkan korelasi dan pemahaman lebih baik tentang peran IL-6 dan IL-10 agar dapat dijadikan sebagai penilaian prognosis dan luaran pada pasien dengan COT berat. Penelitian ini bertujuan untuk mengevaluasi hubungan kadar IL-6 dan IL-10 serum pada pasien dengan COT berat. Jenis penelitian ialah analitik observasional dengan desain potong lintang. Sampel darah vena untuk IL- 6 dan IL-10 serum diambil kurang dari 24 jam pasca trauma. Usia dan jenis kelamin dicatat dan seleksi variabel dilakukan secara bertahap. Digunakan model regresi proporsional untuk menilai hubungan kadar IL-6 dan IL-10 serum pada pasien COT berat. Hasil penelitian mendapatkan 20 pasien dengan COT berat yang masuk ke Instalasi Rawat Darurat Bedah (IRDB). Rerata kadar IL-6 serum 22,0 pg/mL (SD±4,6 pg/mL) dan rerata IL-10 serum 105,7 pg/mL (SD±16,7 pg/mL). Kadar serum kedua biomarker ini relatif tidak jauh berbeda pada laki-laki maupun perempuan. Hasil uji korelasi Pearson mendapatkan nilai r= 0,46 dengan p=0,041. Hasil pemodelan regresi mengindikasikan setiap pg/mL pe","PeriodicalId":17726,"journal":{"name":"JURNAL BIOMEDIK (JBM)","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90776740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Korelasi Posisi Tip Catheter Double Lumen dengan Nilai Quick of Blood pada Pemasangan CDL Tunneling Vena Jugularis Interna Kanan di RSUP Prof. Dr. R. D. Kandou","authors":"Angga P. Tubagus, Djony E. Tjandra, Richard M. Sumangkut","doi":"10.35790/JBM.11.2.2019.23322","DOIUrl":"https://doi.org/10.35790/JBM.11.2.2019.23322","url":null,"abstract":"Abstract: Chronic kidney disease (CKD) is a global public health problem with increasing prevalence and incidence. Patients with CKD require kidney replacement therapy such as hemodialysis. The quick of blood (Qb) value is one of the most important determinants for adequate hemodialysis. Many factors can affect the Qb value, inter alia the catheter tip position. It is very complex and still controversial to determine the optimal position of the catheter itself. This study was aimed to determine the correlation between the double lumen catheter tip position and Qb value in insertion of the right internal jugular vein CDL tunneling at Prof. Dr. R. D. Kandou hospital. This was a correlation analytical study with a cross-sectional design. The position of the CDL tips were evaluated by using chest x-ray and the Qb values were determined by using hemodyalisis machine. Data were analyzed by using point-biserial correlation test. In total, 55 patients were included, mostly were males (56.4%) and late elderly (41.8%). The results showed that the average Qb value with CDL tip position in intraatrial (178.2 ml/minute) was slightly higher than the average Qb value with CDL tip position in CAJ (171.6 ml/minute). The bivariate analysis showed that the position of the double-lumen catheter tip had a weak positive correlation but not significant with the Qb value. Conclusion: There was a correlation but not statistically significant between the position of the CDL tip and the Qb value.Keywords: CKD, catheter tip position, catheter double-lumen, Quick of bloodAbstrak: Penyakit ginjal kronik (PGK) merupakan masalah kesehatan masyarakat global dengan prevalensi dan insidens yang terus meningkat. Pasien gagal ginjal memerlukan terapi pengganti ginjal seperti hemodialisis. Nilai quick of blood (Qb) merupakan salah satu penentu yang sangat penting bagi hemodialisis yang adekuat. Banyak faktor yang dapat memengaruhi nilai Qb, salah satunya ialah posisi tip kateter. Hal yang menentukan posisi optimal dari kateter sendiri sangat kompleks dan masih kontroversial. Penelitian ini bertujuan untuk mengetahui korelasi antara posisi tip kateter double lumen dengan nilai quick of blood pada pemasangan CDL vena jugularis interna kanan di RSUP Prof. Dr. R. D. Kandou Manado. Jenis penelitian ialah analitik korelasi dengan desain potong lintang. Alat ukur yang digunakan ialah foto toraks untuk menentukan posisi tip CDL dan mesin hemodialisa untuk melihat nilai Qb. Data hasil penelitian dianalisis dengan uji korelasi point-biserial. Subyek penelitian ini sebanyak 55 pasien, lebih banyak yang berjenis kelamin laki-laki (56,4%) dan berada dalam kategori usia lansia akhir (41,8%). Hasil penelitian menunjukkan nilai rerata Qb posisi tip CDL di intraatrial (178,2 ml/menit) sedikit lebih tinggi daripada rerata nilai Qb posisi tip CDL di CAJ (171,6 ml/menit). Hasil analisis data mendapatkan korelasi positif lemah dan tidak bermakna (antara posisi tip catheter double-lumen dengan nilai Qb. S","PeriodicalId":17726,"journal":{"name":"JURNAL BIOMEDIK (JBM)","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91065095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validasi International Prostate Symptom Score Versi Bahasa Indonesia pada Penderita Lower Urinary Tract Symptoms di Poliklinik Urologi RSUP Prof. Dr. R. D. Kandou Manado","authors":"Stephanus J. Ch. Tangel, A. Monoarfa, R. Monoarfa","doi":"10.35790/JBM.11.2.2019.23320","DOIUrl":"https://doi.org/10.35790/JBM.11.2.2019.23320","url":null,"abstract":"Abstract: Lower urinary tract symptoms (LUTS) due to BPH frequently occur in elderly men. Indonesian version of International Prostate Symptom Score (IPSS-Ina) is commonly used in the hospitals in Indonesia, including Prof. Dr. R. D. Kandou Hospital in Manado. However, there is still no study about IPSS-Ina validation in Manado. This study was perfomed by giving IPSS-Ina questionnaire to two sample groups, the treatment and the control groups. IPSS validation was tested by correlating the IPSS score and quality of life score. Reliability of IPSS-Ina was also tested by using internal consistancy test and test-retest to the two groups. There were 50 patients that fulfilled the inclusion and exclusion criteria, divided into the two groups as mentioned before. The oldest patients was 67 years in the treatment group, and the youngest one was 21 years in the control group. The Pearson correlation test showed that all correlations had P values <0.05, therefore, all 8 questions in the IPSS-Ina used in patients not yet treated with TURP were valid. The Cronbach test showed that the 8 questions had realibility of 0.93, which meant that the 8 questions translated into Indonesian had very high consistancy. The t test of treatment group before and after TURP resulted in t= 11.221 and a P value <0.001. Conclusion: IPSS-Ina has very good validation and reliability to people in Manado. Therefore, it has similar purpose, intention, and function to WHO version, and it has sensitivity to the changes of symptoms and signs of BPH patients before and after TURP.Keywords: IPSS, LUTS, validation, BPHAbstrak: Lower urinary tract symptoms (LUTS) akibat BPH sering terjadi pada laki-laki usia lanjut. International Prostate Symptom Score (IPSS) versi bahasa Indonesia sudah banyak digunakan di berbagai rumah sakit di Indonesia, termasuk RSUP Prof. Dr. R. D. Kandou Manado. Penelitian ini bertujuan untuk memvalidasi IPSS versi bahasa Indonesia di Manado. Penelitian dilakukan dengan memberikan kuesioner IPSS versi bahasa Indonesia (IPSS-Ina) kepada dua kelompok subyek, yaitu kelompok uji dan kontrol. Validasi IPSS diuji dengan mengorelasikan hasil skor IPSS yang didapat dengan skor kualitas hidup (Quality of Life). Reliabilitas IPSS-Ina diuji melalui dua cara yaitu dengan uji konsistensi internal dan uji test-retest pada kelompok subyek. Hasil penelitian mendapatkan 50 pasien yang memenuhi kriteria inklusi dan eksklusi penelitian, dibagi menjadi dua kelompok (uji dan control). Usia tertinggi 67 tahun pada kelompok uji, dan terendah 21 tahun pada kelompok kontrol. Hasil uji korelasi Pearson mendapatkan semua nilai korelasi memiliki nilai P <0,05, jadi ke 8 pertanyan yang terdapat dalam IPSS-Ina yang digunakan pada pasien yang belum mendapatkan terapi TURP ialah valid. Hasil uji Cronbach memperlihatkan ke 8 pertanyaan ini memiliki reliabiltas sebesar 0,93, yang berarti ke 8 pertanyaan skoring BPH dari WHO yang diterjemahkan ke dalam bahasa Indonesia memiliki konsisten yang sangat ","PeriodicalId":17726,"journal":{"name":"JURNAL BIOMEDIK (JBM)","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86362095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Dietary Habits and Prehypertension among Indonesian Young Adults at Prof. Dr. R. D. Kandou Hospital Manado","authors":"Ribka Wowor","doi":"10.35790/JBM.11.2.2019.23318","DOIUrl":"https://doi.org/10.35790/JBM.11.2.2019.23318","url":null,"abstract":"Abstract: Prehypertension is a warning sign, early in age which denotes the risk of hypertension later on in life. Clinical and academic challenges of medical students may have adverse effect on their lifestyle, predisposing vulnerable subjects to elevated blood pressure. This study was aimed to determine the association between dietary habits and prehypertension among Indonesian young adults in Manado. This was an analytical study with a cross-sectional study. Subjects were 111 medical students (undergraduate and postgraduate) aged between 20-30 years, of either sex. A pre-tested questionnaire was used to elicit the details on physical activity, family history of hypertension, tobacco use, and dietary habits. According to JNC-7 guidelines, a systolic blood pressure (SBP) of 120 to 139 mmHg and/or diastolic blood pressure (DBP) of 80 to 89 mmHg is considered as prehypertension. Of the 111 subjects, 22.5% showed blood pressure levels within the range of prehypertension. Chi-square analysis revealed that junk food consumption (OR=3,152; 95% CI=1,253-7,925; P=0,023), and soft drink consumption (OR=4,747; 95% CI=1,797-12,539; P=0,002) were the risk factors of prehypertension. Conclusion: Dietary habits were associated with the prehypertension among young adults in Manado.Keywords: dietary habits, prehypertension, young adultsAbstrak: Prehipertensi merupakan tanda peringatan dini akan resiko terjadinya hipertensi di kemudian hari. Mahasiswa kedokteran memiliki kesibukan studi terutama pada masa kepaniteraan klinik di Rumah Sakit. Tuntutan dalam pendidikan dan pelayanan sekaligus di RS berdampak terhadap pola aktivitas mereka sehari-hari sehingga dapat memengaruhi tekanan darah. Penelitian ini bertujuan untuk mengetahui hubungan antara diet (konsumsi makanan dan minuman) dengan kejadian prehipertensi pada mahasiswa kedokteran Univrsitas Sam Ratulangi. Jenis penelitian ialah analitik dengan desain potong lintang. Hasil penelitian mendapatkan 111 mahasiswa kedokteran peserta P3D dan PPDS (calon spesialis) berusia antara 20-30 tahun sebagai subyek penelitian. Dilakukan pemeriksaan tekanan darah dan berat badan. Penentuan kebiasaan makan ditetapkan berdasarkan hasil pengisian kuesioner. Definisi prehipertensi berdasarkan kriteria JNC 7 yaitu tekanan darah sistolik lebih dari 120 mmHg tapi kurang dari 140 mmHg, dan atau tekanan darah diastolik lebih dari 80 mmHg tapi kurang dari 90 mmHg. Uji Chi-square dilakukan untuk melihat hubungan antara konsumsi junk food dan soft drink dengan kejadian prehipertensi dan didapatkan adanya hubungan antara konsumsi junk food (OR=3,152; 95% CI=1,253-7,925; P=0,023), dan soft drink (OR=4,747; 95% CI=1,797-12,539; P=0,002) dengan kejadian prehipertensi pada subyek dewasa muda. Simpulan: Diet (konsumsi junk food dan soft drink) berhubungan dengan kejadian prehipertensi pada subyek dewasa muda di Manado.Kata kunci: diet, prehipertensi, dewasa muda","PeriodicalId":17726,"journal":{"name":"JURNAL BIOMEDIK (JBM)","volume":"147 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75510566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prehipertensi sebagai Prediktor Perlemakan Hati Non Alkoholik pada Obesitas Sentral Usia Dewasa Muda","authors":"Fadil Dewantara, F. Wantania","doi":"10.35790/JBM.11.2.2019.23326","DOIUrl":"https://doi.org/10.35790/JBM.11.2.2019.23326","url":null,"abstract":"Abstract: Fatty liver is one of the early complications of obesity in adolescents. This state may develop to steatohepatitis and liver cirrhosis in the future. Recent studies show the association between prehypertension and left ventricular hypertrophy in adolescents. This study was aimed to determine prehypertension as a risk factor of non alcoholic fatty liver disease (NAFLD) in central obesity. This study was conducted at the Department of Internal Medicine Prof. Dr. R. D. Kandou Hospital, Manado. There were 50 medical students (undergraduate and postgraduate) aged 20-40 years of either sex included in this study. Blood pressure, body weight, and waist circumferences were measured. According to JNC-7 guidelines, a systolic blood pressure of 120 to 139 mmHg and/or diastolic blood pressure of 80 to 89 mmHg is considered as prehypertension. The results showed that of 25 subjects with NAFLD, there were 18 subjects with prehypertension, while only 9 subjects with prehypertension in non NAFLD group. There was a significant association between prehypertension and the incidence of NAFLD in central obesity (OR=4,571; CI 95%=1,383-15,109; P=0,011). Conclusion: Prehypertension is a risk factor of NAFLD in young adults with central obesity. We may use prehypertension to predict the occurence of NAFLD in young adults with central obesity.Keywords: prehypertension, fatty liver, central obesityAbstrak: Perlemakan hati merupakan salah satu komplikasi dini dari obesitas yang bisa terjadi sejak usia muda dan dapat berlanjut menjadi sirosis bila tidak segera ditangani. Penelitian terdahulu telah melaporkan adanya hubungan antara prehipertensi dengan pembesaran jantung kiri pada laki-laki usia dewasa muda dengan obesitas sentral. Penelitian ini bertujuan untuk membuktikan apakah prehipertensi dapat dijadikan prediktor penyakit perlemakan hati non alkoholik (PPHNA) pada dewasa muda dengan obesitas sentral. Jenis penelitian ialah analitik dengan studi kohort retrospektif (case-control study). Penelitian dilakukan di RSUP Prof. Dr. R. D. Kandou Manado. Subyek penelitian ialah mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi (FK Unsrat) dan PPDS Ilmu Penyakit Dalam FK UNSRAT dengan obesitas sentral (lingkar perut >90 cm). Diagnosis PPHNA ditegakkan oleh dua radiolog yang berbeda. Diagnosis prehipertensi ditegakkan bila tekanan darah sistolik ≥130 mmHg tetapi <140 mmHg, dan atau tekanan darah diastolik >85 mmHg tetapi < 90 mmHg. Dari 50 subyek penelitian ini, 25 di antaranya dengan PPHNA dan 25 non PPHNA sebagai kelompok kontrol. Pada kelompok PPHNA terdapat 18 subyek dengan prehipertensi dan 7 subyek normotensi. Pada kelompok non PPHNA terdapat 9 subyek dengan prehipertensi dan sisanya dengan normotensi. Uji chi square terhadap hubungan antara prehipertensi dengan kemungkinan terjadi PPHNA pada obesitas sentral mendapatkan adanya hubungan bermakna antara prehipertensi dengan kejadian PPHNA pada subyek (OR=4,571; CI 95%=1,383-15,109; P=0,011). Simpulan: Prehipe","PeriodicalId":17726,"journal":{"name":"JURNAL BIOMEDIK (JBM)","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84982652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteomyelitis: A Literature Review","authors":"Rangga B V Rawung, C. Moningkey","doi":"10.35790/JBM.11.2.2019.23317","DOIUrl":"https://doi.org/10.35790/JBM.11.2.2019.23317","url":null,"abstract":"Abstrak: Infeksi pada tulang dan sendi masih merupakan kasus yang menantang. Kondisi ini memberikan banyak penyulit baik kepada dokter maupun pasien. Meski terapi antibiotika dilaporkan memberikan hasil yang memuaskan pada banyak kasus infeksi, tidak demikian pada kasus infeksi tulang dan sendi. Hal ini berhubungan dengan struktur anatomi dan fisiologi dari tulang. Diperlukan sebuah strategi tata laksana yang baik untuk mencapai hasil yang optimal. Prinsip dasar yang utama dalam mencapai pengobatan yang optimal ialah penegakan diagnosis awal yang tepat, termasuk di dalamnya proses investigasi pemeriksaan mikrobiologi dan patologi. Diperlukan pengertian dasar serta pengenalan kembali anatomi, fisiologi, patofisiologi, dan tata laksana terkini tentang osteomielitis untuk mencapai tatalaksana yang optimal.Kata kunci: diagnosis dan tata laksana osteomielitisAbstract: Infection in bone and joint is still a challenging case. It gives a lot of problems and frustration to the physician and patient. The successful antibiotic therapy in most infectious diseases is abortive to achieve in bone and joint infections because the different characteristic in anatomy and physiology of these structures. Therefore, treatment strategy, including non operative and operative techniques is required to deal with such conditions. The basic principle to achieve a successful management of osteomyelitis in general is correct initial diagnosis including investigation for microbiological and pathological examinations to allow the proper and long term lasting therapy of antibiotic. For that reason, it is required to have the basic understanding in dealing with this issue, obvious and updated. It is commited to review the pathophysiology, the diagnosis, and the management of osteomyelitis in order to presents basic facilities in dealing with osteomyelitis.Keywords: osteomyelitis diagnosis and management","PeriodicalId":17726,"journal":{"name":"JURNAL BIOMEDIK (JBM)","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75636988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}