Journal of the Science of Food and Agriculture最新文献

{"title":"Optimization of kestose production by a Saccharomyces cerevisiae invertase exhibiting selective transfructosylation.","authors":"Sirilak Baramee, Suratsawadee Tiangpook, Apinya Singkhala, Prattana Ketbot, Rattiya Waeonukul, Patthra Pason, Chakrit Tachaapaikoon, Khanok Ratanakhanokchai","doi":"10.1002/jsfa.70503","DOIUrl":"10.1002/jsfa.70503","url":null,"abstract":"<p><strong>Background: </strong>Kestoses, short-chain fructooligosaccharides (FOSs), are valued for their intestinal, immunomodulatory, sweetness, and prebiotic properties compared with longer-chain FOSs. Although invertases are widely used for kestose production, most enzymes generate mixed FOS products. This study investigates a GH32 invertase from Saccharomyces cerevisiae (ScINV), heterologously expressed in Escherichia coli, with an emphasis on its product selectivity for kestose production.</p><p><strong>Results: </strong>Under optimized conditions (600 g L^-1 initial sucrose concentration, 1.0 μmol L^-1 enzyme, pH 6.0, and 45 °C), ScINV produced 54.1 g L^-1 kestoses after 24 h, corresponding to a yield of 9.0% and a purity of 7.5%. Purification by ligand-exchange chromatography using XA2004-30-Ca resin increased kestose purity to 19.4% with complete recovery, whereas higher-resolution fractionation achieved 100% purity with a reduced recovery of 14.9%.</p><p><strong>Conclusion: </strong>ScINV exhibits selective kestose production without formation of higher-degree FOSs. Although partial peak overlap limits single-step recovery, purification using XA2004-30-Ca resin provides a promising basis for scale-up. Coupling this approach with continuous simulated moving bed technology may improve process efficiency and industrial feasibility. © 2026 Society of Chemical Industry.</p>","PeriodicalId":17725,"journal":{"name":"Journal of the Science of Food and Agriculture","volume":" ","pages":"4199-4206"},"PeriodicalIF":3.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146180765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative transcriptome analysis of kiwifruit reveals candidate genes involved in soft rot resistance against Botryosphaeria dothidea.","authors":"Danni Lv, Yuxiao Li, Xiaoxia Zuo, Jing Yang, Guiqing Tu, Jing Wang, Zhipeng Cai, Yonggen Shen, Huaying Du, Wei Zhang, Liqin Zhu","doi":"10.1002/jsfa.70519","DOIUrl":"10.1002/jsfa.70519","url":null,"abstract":"<p><strong>Background: </strong>Soft rot caused by Botryosphaeria dothidea is a common disease in postharvest kiwifruit. Kiwifruit cultivars show varying susceptibility, but the molecular mechanisms underlying these differences are poorly understood.</p><p><strong>Results: </strong>This study revealed that the 'Jinyan' (JY) kiwifruit cultivar exhibited greater resistance to B. dothidea and higher contents of total phenolics, flavonoids, and lignin compared to 'Jinkui' (JK). Transcriptome analysis revealed that 4011 genes were differentially expressed, with 1892 being upregulated and 2119 downregulated, between the resistant (JY) and susceptible (JK) kiwifruit cultivars on the first day post-inoculation. GO and KEGG enrichment analyses indicated that differentially expressed genes (DEGs) were primarily associated with defense response functions and metabolic pathways. The DEGs related to phenylalanine metabolism (DHQS, ADT, TAT, GOT2, 4CL, CHS, CHI, CCR, F5H, BGLU, BGLU2, BGLU4, POD12, POD55), calcium (Ca²⁺) signaling pathway (CALM2, CML23), transcription factors (WRKY22, MYC2), plant hormone signaling pathway (ATP7, ETR, EBF1_2, PP2C16, SAPK2), and MAPK signaling pathway (MKK4_5) were identified as key markers of resistance to B. dothidea. The expression patterns of these genes related to the key pathways were further validated by real-time quantitative polymerase chain reaction; most of these genes show higher expression levels in JY than in JK. In total, these candidate genes and their associated pathways were found to be associated with kiwifruit resistance to B. dothidea-induced soft rot.</p><p><strong>Conclusion: </strong>This study revealed the functional genes and defense pathways involved in governing soft rot resistance in kiwifruit against B. dothidea. These results contribute to understanding the molecular differences in disease resistance between resistant and susceptible kiwifruit cultivars. © 2026 Society of Chemical Industry.</p>","PeriodicalId":17725,"journal":{"name":"Journal of the Science of Food and Agriculture","volume":" ","pages":"4284-4294"},"PeriodicalIF":3.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146194971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic role of silicon and rapeseed cake in enhancing phosphorus dynamics and nutrient biofortification of rice in acidic soils.","authors":"Nader Saad Elsayed, Yinhang Xia, Kai Zhang, Yuxiang Lin, Jiayi Fan, Ola Kh Shalaby, Zhenhua Zhang","doi":"10.1002/jsfa.70548","DOIUrl":"10.1002/jsfa.70548","url":null,"abstract":"<p><strong>Background: </strong>Rice is a major global staple crop; however, zinc (Zn) and iron (Fe) deficiencies highlight the need to improve its nutritional value. In acidic soils, nutrient imbalances often restrict phosphorus (P) availability, limiting crop productivity. Soil amendments such as rapeseed cake (RC), an organic nutrient source, and silicon (Si), a chemical amendment, are used in rice systems, yet their combined effects on soil P dynamics and nutrient biofortification remain poorly understood.</p><p><strong>Results: </strong>A two-season field experiment was conducted in Xiangtan, Hunan Province, China, using four treatments: (1) recommended NPK fertilization (control), (2) RC replacing 30% of urea-N, (3) Si applied at 30 kg SiO₂ ha^-1, and (4) combined application of Si and RC (Si + RC). Soil P fractions, grain yield, phytic acid (PA), and Zn bioavailability were assessed. Both Si and Si + RC significantly increased soil Olsen P by 33-47% (from 9.6 to 12.8-14.1 mg kg^-1) across two seasons. The Si + RC treatment increased exchangeable P by up to 48% and organic-bound P by 38-70%, while reducing mineral-bound P by 18-26%. Importantly, Si + RC reduced shoot-to-grain P translocation by 56-70%, decreased grain PA concentration by 20-25%, and lowered the PA/Zn molar ratio from 22 to 12, indicating improved Zn bioavailability.</p><p><strong>Conclusions: </strong>This short-term field study indicates that RC enhanced sustainability by replacing 30% of urea fertilizer, while the combined application of Si and RC simultaneously enhanced grain biofortification and soil nutrient sustainability in acidic paddy soil. © 2026 Society of Chemical Industry.</p>","PeriodicalId":17725,"journal":{"name":"Journal of the Science of Food and Agriculture","volume":" ","pages":"4363-4371"},"PeriodicalIF":3.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147276599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Egg yolk hydrolysate shows moderate impact on osteoporosis in ovariectomized rats.","authors":"Ilekuttige Priyan Shanura Fernando, Da Shi, Zihan Wang, Michael Doschak, Jianping Wu","doi":"10.1002/jsfa.70511","DOIUrl":"10.1002/jsfa.70511","url":null,"abstract":"<p><strong>Background: </strong>This study investigated the protective effect of egg yolk hydrolysate (FC) on osteoporosis in ovariectomized (OVX) rats, a well-established model of postmenopausal bone loss. OVX rats were fed diets supplemented with 0.2% or 1% FC for 13 weeks. The regulatory effects were evaluated by measuring bone mineral density (BMD) and microarchitecture using computed tomography, analyzing serum bone remodeling biomarkers, and examining osteoclast differentiation and resorption activity in isolated bone marrow cells. Western blotting was used to evaluate the expression of key osteoclastogenic proteins.</p><p><strong>Results: </strong>FC 1% supplementation significantly improved trabecular BMD and percentage bone volume in OVX rats. Treatment with FC 1% also significantly increased serum osteocalcin levels (P = 0.028). Furthermore, FC 1% significantly reduced osteoclast differentiation (decreased tartrate-resistant acid phosphatase-positive area by approximately 49%, P < 0.05) and bone resorption activity. At the molecular level, FC 1% significantly decreased cellular Fos (c-Fos) expression, whereas other osteoclastogenic proteins, including nuclear factor of activated T-cells cytoplasmic 1 (NFATc1), cathepsin K and matrix metalloproteinase 9 (MMP-9), showed non-significant downward trends.</p><p><strong>Conclusion: </strong>These findings indicate that FC exerts moderate protective effects against bone loss in OVX rats by simultaneously suppressing osteoclast activity and enhancing bone formation. These results support the potential of egg yolk hydrolysate as a functional food ingredient for osteoporosis management, particularly in postmenopausal women. Further investigations are needed to fully understand the underlying mechanisms and assess long-term efficacy. © 2026 The Author(s). Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.</p>","PeriodicalId":17725,"journal":{"name":"Journal of the Science of Food and Agriculture","volume":" ","pages":"4218-4227"},"PeriodicalIF":3.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13067072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146150148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolomic and ionomic signatures of maize (Zea mays L.) genotypes exhibiting differential temperature tolerance.","authors":"Salika Ramazan, Rahul Beniwal, Zahoor A Dar, Manzoor A Shah","doi":"10.1002/jsfa.70662","DOIUrl":"https://doi.org/10.1002/jsfa.70662","url":null,"abstract":"<p><strong>Background: </strong>Maize (Zea mays L.) is a major cereal crop of global importance, valued not only for its nutritional importance but also for its diverse phytochemical composition. Metabolomics offers a comprehensive platform to investigate physiological and biochemical alterations caused by various factors and facilitates the analysis of metabolic alterations associated with varying temperature tolerance in maize genotypes.</p><p><strong>Results: </strong>In the present study, we employed gas chromatography-mass spectrometry-based untargeted metabolomics, X-ray fluorescence-based elemental profiling, seedling-stage morphological assessment, and priming-mediated germination assays to evaluate three maize genotypes differing in low-temperature (LT) tolerance from the Kashmir Himalayas. A total of 68 metabolites were identified, with unique genotype-specific distributions as follows: 19 in SMC-7 (LT susceptible), 23 in SMC-4 (moderately LT tolerant), and eight in KG-3 (LT tolerant). The rest of the metabolites were shared among the genotypes. KG-3 was characterized by the accumulation of diverse secondary metabolites with potential pharmacological relevance, whereas SMC-4 showed relative enrichment in functional fatty acids and rare sugars. In contrast, SMC-7 exhibited higher levels of polyols and primary sugars that may be associated with general metabolic functions. However, the implications of all these metabolites in terms of dietary and health relevance remains to be further validated. Elemental analysis revealed significant genotype-specific differences in micronutrient allocation, with KG-3 exhibiting elevated levels of K, Fe, and Zn, which could be related to its better agronomic performance and tolerance under LT stress. Morphological evaluation further confirmed KG-3 as highly adaptable to LT conditions. In seed priming experiments, a combined treatment of 50 mmol L^-1 KNO₃ and 8 mmol L^-1 H₂O₂ resulted in the highest germination rate (100%), with SMC-7 and SMC-4 responding more positively than KG-3.</p><p><strong>Conclusion: </strong>Collectively, these findings highlight the metabolic, nutritional, and physiological bases of differential LT tolerance in maize genotypes, and suggest that genotypes such as KG-3 hold promise for both stress-resilient cultivation and nutritional enhancement in temperate agroecosystems. © 2026 Society of Chemical Industry.</p>","PeriodicalId":17725,"journal":{"name":"Journal of the Science of Food and Agriculture","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Yak whey powder enhanced antioxidant activity in aging mice by regulating gut microbiota.","authors":"Xiaojing Tian, Qianyu Wang, Weinan Zhang, Shuqin Chen, Fumei Zhang, Jia Wei, Yumei Wei, Gendi Liu, Li Song, Tisong Liang, Zilin Qiao","doi":"10.1002/jsfa.70639","DOIUrl":"https://doi.org/10.1002/jsfa.70639","url":null,"abstract":"<p><strong>Background: </strong>The aging process is closely related to the accumulation of oxidative stress and imbalance in the gut microbiota. Yak whey powder is rich in various bioactive components; however, whether it can improve the antioxidant status of aging organisms by regulating gut microbiota remains to be elucidated. This study aims to investigate the effects of yak whey powder on d-galactose-induced aging mice by evaluating its impact on antioxidant capacity, gut microbiota, and fecal odor profiles.</p><p><strong>Results: </strong>Intervention with yak whey powder significantly improved the content of superoxide dismutase, thymus index, and weight-gain rate in aged mice, while concurrently reducing malondialdehyde levels. The structure and relative abundance of gut microbiota were regulated, characterized by an increase in the levels of beneficial Lactobacillus and a decrease in the levels of potentially pathogenic Helicobacter. Furthermore, fecal odor varied among different interventions and was effectively discriminated with canonical discriminant analysis. Significant correlations (P < 0.05) were observed among the antioxidant indices, relative abundance of intestinal microbiota, and fecal odor information.</p><p><strong>Conclusion: </strong>This study demonstrated that yak whey powder ameliorated oxidative stress and modulated gut dysbiosis in aged mice. The strong correlations between the microbiota, odor profiles, and antioxidant markers suggested that the gut microbiota mediated the antioxidant effects of yak whey powder. These findings established a theoretical foundation for understanding the antioxidant properties of yak whey powder, and provided direction for its development and utilization. © 2026 Society of Chemical Industry.</p>","PeriodicalId":17725,"journal":{"name":"Journal of the Science of Food and Agriculture","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating phenotypic traits, multivariate statistics, and machine-learning models to predict yield in Himalayan kiwifruit (Actinidia deliciosa) orchards.","authors":"Shilpa Sharma, Rakesh Kumar Gupta, Vishal Singh Rana, Umesh Sharma","doi":"10.1002/jsfa.70689","DOIUrl":"https://doi.org/10.1002/jsfa.70689","url":null,"abstract":"<p><strong>Background: </strong>Understanding the morphological and physiological determinants of kiwifruit (Actinidia deliciosa A. Chev.) yield is essential to improve orchard productivity in Himalayan hill agro-ecosystems. However, most previous studies have focused on individual agronomic factors and have rarely integrated multivariate phenotypic traits with advanced predictive modeling approaches. The aim of this study was to evaluate whether combining multivariate statistical techniques with machine-learning algorithms could improve identification of key traits influencing yield variability in Himalayan kiwifruit orchards.</p><p><strong>Results: </strong>Thirty vegetative, floral, phenological, and fruit biometric traits were recorded from 210 vines of Actinidia deliciosa 'Allison' across three major kiwifruit-growing districts of Himachal Pradesh, India. Descriptive analysis revealed substantial phenotypic variability in canopy vigor, flowering intensity, and fruit morphology. Correlation analysis showed that fruit number per shoot, fruit width, and flowering duration were associated positively with total fruit yield, whereas leaf-to-fruit ratio showed a negative association. Principal component analysis identified five components explaining 79.1% of total phenotypic variance, representing canopy vigor, floral load, fruit morphology, and source-sink balance. Among machine-learning models, random forest achieved the highest predictive accuracy (R² = 0.84; RMSE = 6.20 kg), outperforming gradient boosting and support vector regression. Feature importance analysis consistently identified fruits per shoot, fruit width, vine girth, flowering duration, and leaf-to-fruit ratio as the most influential predictors.</p><p><strong>Conclusion: </strong>The integration of multivariate statistical analysis with machine learning provides a robust framework for identifying key trait-based indicators of yield variability. These findings can support clonal selection, optimized pruning strategies, and site-specific orchard management to increase productivity in Himalayan kiwifruit systems. © 2026 Society of Chemical Industry.</p>","PeriodicalId":17725,"journal":{"name":"Journal of the Science of Food and Agriculture","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrative review on the domestication process and secondary metabolism of Ugni molinae: From ecological functions to food applications.","authors":"Manuel Chacón-Fuentes, César Burgos-Díaz, Mauricio Opazo-Navarrete, Grace Armijo-Godoy, Macarena Barra, Javier Espinoza, Leonardo Bardehle","doi":"10.1002/jsfa.70691","DOIUrl":"https://doi.org/10.1002/jsfa.70691","url":null,"abstract":"<p><p>Ugni molinae, a Patagonian berry traditionally consumed fresh and increasingly explored for value-added applications, has attracted growing interest for the functional food industry due to its distinctive sensory attributes and bioactive profile. The domestication program initiated by Instituto de Investigaciones Agropecuarias (INIA) in 1996 led to the development of cultivars such as Red Pearl INIA and South Pearl INIA, improving fruit quality and yield and being associated with shifts in secondary metabolite profiles that may depend on genotype, environment, and management conditions. This metabolism includes phenolics, flavonoids, carotenoids, and pentacyclic triterpenoids associated with antioxidant and antimicrobial activities. Evidence suggests that domestication may alter specific flavonol profiles, indicating possible trade-offs between agronomic traits and ecological functions. This integrative review was conducted through structured searches in Scopus, Web of Science, and PubMed databases covering publications from 2000 to 2025 using combinations of the terms 'Ugni molinae', 'murtilla', 'murta', and 'Chilean guava'. Peer-reviewed articles published in English or Spanish addressing domestication, propagation, phytochemistry, chemical ecology, and food applications were screened for relevance, resulting in 96 studies included in the final synthesis. Previous reviews have primarily addressed phytochemical composition and biological activities of U. molinae. The objective of this review is to provide an integrated overview of the species, encompassing its domestication history, propagation strategies, secondary metabolite composition, ecological roles, and emerging food applications. By linking chemical ecology with technological potential, this work addresses an underexplored integrative dimension and identifies current knowledge gaps and future research priorities required to support the sustainable valorization of this native species. © 2026 Society of Chemical Industry.</p>","PeriodicalId":17725,"journal":{"name":"Journal of the Science of Food and Agriculture","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construction of a xanthan gum-sodium carboxymethylcellulose hydrogel for enhanced gastrointestinal stability and in vivo calcium bioavailability of Mytilus edulis-derived peptide-calcium complex.","authors":"Guang Li, Xuening Yu, Yuewen Xu, Xiaoyang Liu, Dayong Zhou","doi":"10.1002/jsfa.70678","DOIUrl":"https://doi.org/10.1002/jsfa.70678","url":null,"abstract":"<p><strong>Background: </strong>Calcium is an important mineral nutrient for the body, playing a crucial role in bone growth. However, it has been demonstrated that calcium bioavailability is reduced due to the action of gastric acid and digestive enzymes on peptide-calcium chelates. Therefore, enhancing the structural stability of calcium in the complex environment of the gastrointestinal tract through a novel delivery system is a key strategy for improving calcium bioavailability. In this study, hydrogels (XC) composed of xanthan gum (XG) and sodium carboxymethylcellulose (CMC) were employed as carriers for Mytilus edulis protein hydrolysate-calcium (ME-Ca), thereby forming composite hydrogels (XCME-Ca).</p><p><strong>Results: </strong>The optimal formulation for the XC hydrogels was determined (XG: 20 mg mL^-1; CMC: 10 mg mL^-1). XCME-Ca hydrogels exhibited distinctive properties, including a shift in the ultraviolet-visible, decreased fluorescence intensity, alterations in infrared spectra and X-ray diffraction peaks, enhanced thermal stability, and changes in microstructure. In a calcium-deficient mouse model, the XCME-Ca-M hydrogel (Ca²⁺: 133.33 mg kg^-1) was observed to restore femur and tibia weight by 12.18% and 26.66%, respectively, and length by 5.19% and 15.34%, respectively, when compared with the model group. Furthermore, the maximum bone load attained 87.44% and 88.69% of the control group, respectively, with significant reparative effects observed on microstructural damage in both the femur and the tibia.</p><p><strong>Conclusion: </strong>The results indicate that the development of the hydrogel system addresses key issues such as poor stability and low bioavailability of peptide-calcium chelates in the gastrointestinal environment, providing an innovative solution to enhance their calcium absorption efficacy. © 2026 Society of Chemical Industry.</p>","PeriodicalId":17725,"journal":{"name":"Journal of the Science of Food and Agriculture","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interaction between Chinese olive (Canarium album L.) polyphenols and gut microbiota: Potential implications for inflammatory bowel disease.","authors":"Shuzhen Zhang, Fangqing He, Huize Zeng, Yu He, Junfan Mai, Meiying Li","doi":"10.1002/jsfa.70685","DOIUrl":"https://doi.org/10.1002/jsfa.70685","url":null,"abstract":"<p><strong>Background: </strong>Polyphenols' interaction with gut microbiota is crucial for their bioactivity and intestinal health benefits, yet this effect varies individually due to differences in microbiota structure. Using fecal samples from healthy individuals (n = 3), ulcerative colitis (UC) patients (n = 3), and Crohn's disease (CD) patients (n = 3), we employed an in vitro digestion and fermentation model combined with 16S rRNA sequencing to compare polyphenol-microbiota interactions among these groups.</p><p><strong>Results: </strong>Polyphenol intervention consistently increased Bifidobacterium abundance while decreasing Firmicutes and Bacteroidetes across all groups. Meanwhile, there were significant differences among the groups in the abundance of certain bacterial genera such as Akkermansia, Enterobacter, and Lactobacillus, as well as in the production of short-chain fatty acids like propionate, butyrate, and isobutyrate. Further analysis revealed that in the healthy group, the relative abundance of some beneficial bacteria (such as Akkermansia) was positively correlated with the level of catechins, while in the UC and CD groups, the proliferation of inflammation-related bacterial genera such as Flavonifractor promoted the production of benzoic acid.</p><p><strong>Conclusion: </strong>This study elucidated the adaptive regulation of polyphenols on different gut microbiota and the role of microbiota in modulating the differentiation of polyphenol metabolites, providing a theoretical basis for the development of precision nutrition intervention strategies for inflammatory bowel disease (IBD) based on the interaction between microbiota and polyphenols. © 2026 Society of Chemical Industry.</p>","PeriodicalId":17725,"journal":{"name":"Journal of the Science of Food and Agriculture","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}