Journal of Vector Borne Diseases最新文献

{"title":"Indicators sandflies and environment associated to spatial landscaping change in Chocó Biosphere Reserve UNESCO.","authors":"Sandra Enríquez, Jazzmín Arrivillaga-Henríquez, Paul Duque, Vanessa Herrera, Franklin Vaca, Marco Sánchez, Mateo Roldán, Lenin Ron-Garrido, C Alfonso Molina","doi":"10.4103/jvbd.jvbd_52_23","DOIUrl":"10.4103/jvbd.jvbd_52_23","url":null,"abstract":"<p><strong>Background objectives: </strong>Sandflies are vector insects associated with terrestrial forest ecosystems; in the Ecuadorian Andes, they participate in the transmission of human cutaneous leishmaniasis. This geographical area represents an opportunity to evaluate the role of sandflies as bioindicators of the degree of intervention of tropical humid forest ecosystems (THF) associated with changes in the ecology of the local landscape.</p><p><strong>Methods: </strong>CDC-light traps were used for collecting adult sandflies in February 2020 in a humid tropical forest within the Chocó Biosphere Reserve. All species were identified using morphological keys. Analysis data about abundance, richness, species accumulation, diversity index, species composition communities, species sex proportion, spatial sandflies environmental, Renyi's Diversity Profile were performed to compare six spatial habitats in Mashpi locality, Ecuador.</p><p><strong>Results: </strong>Sandflies were collected (n-1435); the main species are represented by Trichophoromyia reburra, Nyssomyia trapidoi, Psathyromyia aclydifera, Psychodopygus panamensis and Lutzomyia hartmanni. Only Th. reburra is associated with not intervened forest, while the other three species are associated with intervened forest within Mashpi in the Choco Biosphere Reserve. The secondary forest has major sandflies' richness, while the primary forest exhibits major abundance.</p><p><strong>Interpretation conclusion: </strong>Th. reburra is a sandfly restricted to the Andean Forest and is a bioindicator of the high environmental health quality of the forest, while Ny. trapidoi and Pa. aclydifera are bioindicators of environmental disturbances in the forest. Additionally, Ps. panamensis, Lu. hartmanni and Ny. trapidoi are bioindicators of human impact and the risk of leishmaniasis.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":"61 2","pages":"236-242"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141450783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effectiveness of training mothers with regard to pediculosis preventive behavior among school students: A Protection Motivation Theory study.","authors":"Roghayeh Mohammadpour, Siamak Mohebi, Abolfazl Mohammadbeigi, Zeynab Gholamrezaee-Sarvelat, Roghaye Ahangari, Alireza Omidi Oskouei","doi":"10.4103/jvbd.jvbd_146_22","DOIUrl":"10.4103/jvbd.jvbd_146_22","url":null,"abstract":"<p><strong>Background objectives: </strong>Lice infestation is considered as a reemerging problem as well as a health challenge. Based on Protection Motivation Theory, the present study was conducted to investigate the effectiveness of training mothers in regard to pediculosis preventive behavior among school students.</p><p><strong>Methods: </strong>In a critical trial, 180 mothers of primary school daughters were assessed in two study groups in the Iranian city of Qom in 2021. They received training intervention in a course of four ninety-minute sessions during four weeks. After six months, the post-test questionnaire and the checklist were completed by them. The data were gathered using a valid and reliable questionnaire. Finally, data analysis was performed using SPSS 20.</p><p><strong>Results: </strong>After the training intervention, a significant difference was observed within the intervention group in scores of the prevention motivation constructs (P<0.001). Besides, there was a significant difference between the mean scores of the preventive behavior of the mothers and daughters in the intervention group before the training intervention and six months after it (P<0.001). However, no significant difference was seen before and after the intervention in the control group (P>0.05). Additionally, no significant differences were observed between the intervention and control groups (P<0.001) in terms of comparing the mean score differences of all the constructs of protection motivation theory, the mothers' behavior and the daughters' behavior checklist.</p><p><strong>Interpretation conclusion: </strong>The results indicate the effectiveness of training mothers based on Protection Motivation Theory in regard to pediculosis. Therefore, it seems that in developing training programs, utilizing this theory could prove useful to bring about changes in the individuals' behavior regarding the prevention of pediculosis.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":"61 2","pages":"195-202"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141450826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structure-based virtual screening study for identification of potent insecticides against Anopheles gambiae to combat the malaria.","authors":"Nawal Helmi","doi":"10.4103/jvbd.jvbd_158_23","DOIUrl":"10.4103/jvbd.jvbd_158_23","url":null,"abstract":"<p><strong>Background objectives: </strong>Vector-borne infectious diseases contribute significantly to global mortality, with over 700,000 annual deaths, and malaria alone accounts for more than 400,000 of these fatalities. Anopheles gambiae, a prominent mosquito species, serves as a primary vector for transmitting malaria to humans. To address this issue, researchers have identified the D1-like dopamine receptor (DAR), specifically DOP2, as a promising target for developing new insecticides.</p><p><strong>Methods: </strong>The three-dimensional structure of DOP2 from A. gambiae was unavailable; in-silico approach was used to model and validate DOP2 structure. The Discovery Studio 2021 program was used to identify potential binding sites on DOP2. Virtual screening of 235 anti-parasitic compounds was performed against DOP2 using PyRx 0.8.</p><p><strong>Results: </strong>The screening demonstrated strong binding and interactions with active site residues of DOP2 for five compounds: Diclazuril, Kaempferol, Deracoxib, Clindamycin, and Diaveridine. These compounds exhibited higher binding affinity values compared to the control (Asenapine). In addition, the predicted physiochemical properties for these compounds were within acceptable ranges and there were no violations in drug-likeness properties.</p><p><strong>Interpretation conclusion: </strong>These compounds show promise as potential new insecticides targeting A. gambiae mosquito by inhibiting the DOP2 protein. However, additional experimental validation is required to optimize their efficacy as DOP2 inhibitors.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":"61 2","pages":"253-258"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141450825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microscopic and molecular investigation of vector borne haemoprotozoan diseases in dromedary camel of North Gujarat, India.","authors":"Dhyanjyoti Sarma, Bhupamani Das, Niral Patel, Arun Patel, Abhinav Suthar, Ankit Prajapati, R M Patel","doi":"10.4103/jvbd.jvbd_105_23","DOIUrl":"10.4103/jvbd.jvbd_105_23","url":null,"abstract":"<p><strong>Background objectives: </strong>Vector-borne haemoprotozoan diseases comprise diverse group of single celled organism transmitted by haematophagus invertebrates. The current study was aimed at the identification of major haemoprotozoan (Babesia, Theileria and Trypanosoma) in dromedary camel of North Gujarat region in India using microscopy and Polymerase Chain Reaction (PCR).</p><p><strong>Methods: </strong>A total of 234 blood samples were screened by the microscopic and molecular detection assays. Molecular prevalence studies of Theileria, Trypanosoma spp and Babesia was undertaken using 18s ribosomal DNA, RoTat 1.2 and SS rRNA gene respectively. The data relating to microscopic and molecular prevalence along with associated risk factors were analysed by statistical methods.</p><p><strong>Results: </strong>The overall prevalence of hamoprotozoan disease based on microscopic and molecular investigation was 23.50%. The sensitivity and specificity (95% Confidence Interval) of PCR assay was 100% in comparison to microscopy (45.45 % sensitive and 100 % specific). The kappa coefficient between PCR and microscopy indicated good level of agreement with a value of 0.704 and SE of 0.159.</p><p><strong>Interpretation conclusion: </strong>Despite holding much significance to the animal sector, little work has been undertaken in regional parts of India regarding camel parasites. The present study offers first preliminary research data investigating haemoprotozoan disease using parasitological and molecular methods in camels in the region.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":"61 2","pages":"259-266"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141450824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bamboo stumps that are artificially in use put pressure on dengue and chikungunya vector control in Dhaka city, Bangladesh.","authors":"Rajib Chowdhury, Shyla Faria, Vashkar Chowdhury, Md Sahidul Islam, Shireen Akther, Sakila Akter","doi":"10.4103/jvbd.jvbd_152_23","DOIUrl":"10.4103/jvbd.jvbd_152_23","url":null,"abstract":"<p><strong>Background objectives: </strong>Aedes aegypti and Ae. albopictus mosquitoes breed in natural and artificial containers, and they transmit dengue and chikungunya. A study was conducted to identify the contribution of bamboo stumps to these disease vectors that were used in the flower garden as pillars to hold the bamboo flex fence.</p><p><strong>Methods: </strong>Two sizes of whole bamboo were used to hold fences around gardens at Dhaka University, Bangladesh, and were painted red and green. Mosquito larvae and pupae were collected from bamboo stumps between July and August, and vectors were identified up to the species level. The data were analyzed using the STATA/MP 14.2 version.</p><p><strong>Results: </strong>83.5% and 0.2% were Ae. albopictus and Ae. aegypti, respectively, and the remaining were Culex and Ar-migeres species. Ae. albopictus, Ae. aegypti, and both species-positive bamboo stumps were 46.9, 0.7, and 47.1%, respectively. 54.5% of the bamboo stumps had at least one mosquito species. The average stump depth for Aedes positive stumps (mean=11.7 cm, SE = 0.5) was significantly (p <0.001) higher than the Aedes negative stumps (mean = 9.5 cm, SE = 0.4). 53.8% and 38.0% stumps were found Aedes positive on the ground and upper sides of fences, respectively, and found significant (p<0.01) differences between both sides. A zero-inflated negative binomial count model is significant at a 5% level of significance, χ2(4) = 11.8, p = 0.019 (<0.05) for Ae. albopictus. Stump depth is found to have a significant positive effect on the number of Aedes-positive stumps.</p><p><strong>Interpretation conclusion: </strong>Artificially used natural containers are adding pressure to current mosquito control activities as mosquitoes are breeding on them, which needs additional attention.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":"61 2","pages":"227-235"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141450778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of repellent from patchouli (Pogestemon cablin) varieties of Southeast Sulawesi against Aedes aegypti.","authors":"Reni Yunus, Mubarak, Nurhayu Malik, Dian Yuniar Syanti Rahayu, Muhammad Sultanul Aulyah, Ida Mardhiah Afrini","doi":"10.4103/jvbd.jvbd_38_22","DOIUrl":"10.4103/jvbd.jvbd_38_22","url":null,"abstract":"<p><strong>Background objectives: </strong>The incidence of Dengue Hemorrhagic Fever (DHF) continues to increase over time in the world, including Indonesia. One of the prevention efforts against dengue virus transmission is to avoid vector mosquito bites by the use of repellants. Using repellents can reduce exposure to mosquito bites that may cause infection with the dengue virus. This study aimed to determine the effectiveness of repellent lotion composed of patchouli batik extract (Pogostemon cablin) from Southeast Sulawesi varieties against Aedes aegypti mosquitoes.</p><p><strong>Methods: </strong>The research subjects were Aedes aegypti adult mosquitoes. The research consisted of three stages. The first stage was a phytochemical test (qualitative method), the second stage was the analysis of patchouli essential oil (GC-MS method) and the third stage was a test of the effectiveness of lotions made from patchouli extract in lotion preparations against Aedes aegypti.</p><p><strong>Results: </strong>The results of the effectiveness test of patchouli leaf repellent (Pogestemon cablin) lotion preparations were as follows: for a concentration of 2.5%, protective power 81.5%; concentration 5%, protection power 83.67%; concentration 7.5%, protection power 88.64 %; the concentration of 10%, protection power 90.44%, and the concentration of 12.5% had protection power 90.89%. Probit analysis and linear regression showed the value of ProbitLc 50 was 6.631.</p><p><strong>Interpretation conclusion: </strong>The results of the effectiveness test of Pogestemon cablin repellent lotion preparations with the most effective concentrations were 10% and 12.5%. The results of ANOVA test indicated there was no difference in the average value of the protection power in patchouli leaves.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":"61 2","pages":"167-175"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141450781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The potential habitat and environmental fitness change of Aedes albopictus in Western Eurasia for 2081-2100.","authors":"Attila J Trájer","doi":"10.4103/jvbd.jvbd_143_23","DOIUrl":"10.4103/jvbd.jvbd_143_23","url":null,"abstract":"<p><strong>Background objectives: </strong>The range of Aedes albopictus, the most important vector mosquito in Western Eurasia is growing due to climate change. However, it is not known how it will influence the habitats occupied by the species and its environmental fitness within its future range.</p><p><strong>Methods: </strong>To study this question, the habitat characteristic of the mosquito was investigated for 2081-2100.</p><p><strong>Results: </strong>The models suggest a notable future spread of the mosquito in the direction of Northern Europe and the parallel northward and westward shift of the southern and eastern potential occurrences of the mosquito. The models suggest a notable increase in generation numbers in the warmest quarter, which can reach 4-5 generations in the peri-Mediterranean region. However, both the joint survival rate of larvae and pupae and the number of survival days of adults in the warmest quarter exhibit decreasing values, as does the potential disappearance of the mosquito in the southern regions of Europe and Asia Minor, along with the growing atmospheric CO2 concentration-based scenarios.</p><p><strong>Interpretation conclusion: </strong>While in 1970-2000 Aedes albopictus mainly occupied the hot and warm summer temperate regions of Europe, the species will inhabit dominantly the cool summer temperate (oceanic) and the humid continental climate territories of North and North-Eastern Europe in 2081-2100.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":"61 2","pages":"243-252"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141450827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An eco-epidemiological analysis of dengue outbreak in Port Blair, South Andaman Island, India.","authors":"Sasmita Rani Jena, M Kaliyamoorthy, T K Bhattacharyya, Kalpana Baruah","doi":"10.4103/jvbd.jvbd_144_23","DOIUrl":"10.4103/jvbd.jvbd_144_23","url":null,"abstract":"<p><strong>Background objectives: </strong>In Port Blair, the capital of Andaman & Nicobar Islands, in the Bay of Bengal, India, there was a sudden increase in fever cases resembling the symptoms of dengue in the monsoon period of 2022. Hence, an investigation was carried out to find out epidemiological and entomological reasons behind the outbreak.</p><p><strong>Methods: </strong>An entomological survey was carried out in 24 wards of Port Blair Municipal Council (PBMC) area, epidemiological data of last six years (January-December 2017-2021 and January-October 2022) and patient details of the year 2022 were collected. Both the epidemiological and entomological data were analyzed concerning time and place.</p><p><strong>Results: </strong>During this outbreak period tyres (22.4%) came out as a major breeding habitat followed by small discarded materials (17.5%), metal drums (15.3%), and plastic drums (11.7%). In rainy season, peri-domestic breeding (55%) was more than the domestic breeding (45%) habitat. Ae. aegypti had a high preference for indoor large containers (100-1000 L) like plastic tank, metal drum and cement tank whereasAe. albopictus prefers to breed in medium sized plastic container (20-100 L) and outdoor water receptacles like tyres, flower pots, and domestic discarded materials.</p><p><strong>Interpretation conclusion: </strong>By source reduction, indoor space spray and outdoor fogging, vector density was controlled which curtailed the transmission and within eight weeks a decreasing trend of dengue cases was noticed. A regular entomological survey is crucial to know the seasonality and key breeding habitats of the vector for proper planning of vector control.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":"61 2","pages":"220-226"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141450777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Cutaneous Leishmaniasis lesion caused by Leishmania major Using Leech Therapy in BALB/c Mice.","authors":"Leila Shirani-Bidabadi","doi":"10.4103/JVBD.JVBD_114_22","DOIUrl":"https://doi.org/10.4103/JVBD.JVBD_114_22","url":null,"abstract":"<p><strong>Background objectives: </strong>Amphotericin B, Allopurinol, Glucantime and Beta-Glucan are the main drugs currently used for the treatment of cutaneous leishmaniasis. In present study, we evaluated the effect of medical leeches on BALB/c mice models infected with Leishmania parasites.</p><p><strong>Methods: </strong>To create animal models of leishmaniasis, BALB/c mice were inoculated with the standard Leishmania major strain MRHO / IR / 75 / ER. Treatment was performed through blood sampling with leeches. We used medical leech (Hirudo medicinalis) species. This leech is a European medicinal leech, one of several species known used as medicinal leech. 22 mice infected with Leishmania major were used for the tests .The studied mice were divided into two groups which were named with the letters L and D. The duration of blood sampling was 25 min for initial treatment, 20 min for the 2nd blood sampling and 15 min for the third times and onwards. Meglumine antimoniate (Glucantime) is a pentavalent antimony (SbV) that recommended by the World Health Organization as a golden standard treatment for all kind of leishmaniasis, but many side effects are still reported. Criteria for anti-leshmania assessment of Leech were including: Leech saliva has an anti-leishmania effect by acting on the purin pathway. Leech saliva prevents the growth and multiplication of Leishmania by a mechanism of action similar to Glucantim (breaking ATP).</p><p><strong>Results: </strong>The duration of leech treatment in BALB/c mice infected with L.major parasites was about 6-8 weeks. Out of the 22 leishmaniasis mice models that underwent treatment, 13 survived until the end of the treatment duration. The recovery rate was about 56%; lesions improved in five out of the 13 surviving mice models. Paired t-test showed a significant difference between the mean wound size at the beginning of treatment and the 8th week of treatment (PV <0.0001).</p><p><strong>Interpretation conclusion: </strong>Considering the fact that the standard drugs for the treatment of leishmaniasis have many side effects, alternative therapies such as leech therapy can be effectively used to treat these chronic wounds. There are about 20 active substances in leech saliva. These substances include antistasin, eglins, guamerin, hirudin, saratin, bdellins, complement, and carboxypeptidase inhibitors. Leech saliva is an anticoagulant, anti-inflammation and prevents the platelet. Leech therapy was effective in treating leishmaniasis wounds in BALB/c mice. In this study, there was complete wound healing in 56% of the mice models.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139735566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distribution changes of cutaneous leishmaniasis: A postulated risk of disease transmission in Hambantota, Sri Lanka.","authors":"K A Mangala Sudarshani","doi":"10.4103/0972-9062.393969","DOIUrl":"https://doi.org/10.4103/0972-9062.393969","url":null,"abstract":"<p><strong>Background objectives: </strong>Leishmaniasis is caused by various species of Leishmania. Approximately 20 of them are pathogenic to mammals. In Sri Lanka, cutaneous leishmaniasis (CL) is an established vector-borne disease. CL originates and spreads mainly through sand fly bite in many endemic countries. Objective of the present study was to compare the geographical distribution and demographic features of CL cases in 2014 and 2016 in Hambantota district, Sri Lanka.</p><p><strong>Methods: </strong>The patients who were presented to the Tangalle Base Hospital from June to December in 2014 and 2016 were examined and a descriptive study was carried out using a structured-questionnaire. Slit -skin smears were collected from each patient, Giemsa-stained and examined under the light microscope to identify Leishmania amastigotes.</p><p><strong>Results: </strong>Out of 256 and 314 suspected CL patients, 156 and 155 were identified positive for the year 2014 and 2016 respectively. Out of 12 District Secretary Divisions in the Hambantota district, highest number of CL cases, 85 and 86 was reported from Tangalle DSD in 2014 and 2016 respectively. Number of identified CL patients in Beliatta DSD had increased from 50 to 67 during the study period. In both years, majority of the CL patients were ≥ 50 years old with males more infected than females. Although CL association with occupations were insignificant, housewives were the highly (23%) infected occupants in this area.</p><p><strong>Interpretation conclusion: </strong>Based on present findings, geographical distribution within DSDs in Hambantota district had changed. It emphasizes the importance of CL as a health problem in Hambantota district.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139491602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}