Journal of Vector Borne Diseases最新文献

{"title":"Impact of diverse musical genres on blood-feeding and mating behavior in Aedes aegypti mosquitoes.","authors":"Chew Yan Ni, Nur Faeza Abu Kassim, Noor Moukhni Ayub, Sara Abdelrahman Abuelmaali, Abadi M Mashlawi, Hamady Dieng","doi":"10.4103/JVBD.JVBD_111_24","DOIUrl":"10.4103/JVBD.JVBD_111_24","url":null,"abstract":"<p><strong>Background objectives: </strong>Sound plays an important role in mosquito foraging and sexual interactions. Mosquitoes utilize acoustic signals for host location, sexual recognition, and mating, which is achieved through the rhythmic beating of their wings to generate distinct sounds characterized by specific flight tone frequencies.</p><p><strong>Methods: </strong>In this study, electronic music (Tremor by Dimitri Vegas, Martin Garrix and Like Mike) and country music (Country Road by John Denver) were played in high and low volumes to investigate the influence of different genres of music on the blood feeding and mating responses of Aedes aegypti . The observations encompassed monitoring the landing attempts, blood-feeding endeavors, and mating behavior of Ae. aegypti.</p><p><strong>Results: </strong>High-volume electronic and country music with elevated pitch and amplitude significantly reduced host attacks and blood-feeding attempts by female mosquitoes compared to low-volume or music-off conditions.</p><p><strong>Interpretation conclusion: </strong>However, significant reduction of successful copula was only observed in Ae. aegypti mosquitoes exposed under electronic music with high volume. As transmission of dengue is through blood feeding and mating, this discovery may open new possibilities for developing music-based control strategies against mosquito-borne diseases.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"211-217"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142786097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serotypic and genotypic profile of dengue virus outbreaks in India between 2011 and 2017.","authors":"Ashvini Kumar Yadav, Divya Namdeo, Prashant Khare, Shashwati Nema, Abhijit Pakhare, Rashmi Chowdhary, Debasis Biswas","doi":"10.4103/JVBD.JVBD_101_24","DOIUrl":"10.4103/JVBD.JVBD_101_24","url":null,"abstract":"<p><p>The epidemiology of dengue has been demonstrating significant changes in recent years, with rising incidence of infection in countries with known endemicity and occurrence of fresh outbreaks in previously unaffected territories. India, which has been a traditional hotspot dengue virus (DENV) transmission in the endemic south-east Asian region, has been affected by the sweeping changes in dengue epidemiology. Two remarkable developments characterize the alterations witnessed by India from 2011-2017. First, all parts of the country have witnessed abrupt replacement of existing DENV lineages with emerging novel strains. Second, co-circulation of multiple serotypes of DENV have been reported from all across the country from 2011-2017; thereby hinting at the transition of the country towards hyper-endemicity. Considering the potential clinical implications of such epidemiological transformation in terms of increasing involvement of pediatric patients and growing predisposition to serious complications, the present review provides an update on the serotypic and genotypic profile of dengue outbreaks that have been witnessed by different zones of India between 2011 and 2017. Dividing the country into northern, southern, eastern, western, central and north-eastern zones, we describe discrete zone-specific distribution patterns of DENV serotypes and genotypes and observe simultaneous circulation of different DENV strains in different parts of the country. Random shifts in the genetic characteristics of the circulating strains and widespread co-circulation of all four serotypes underscore the need for undertaking continuous and representative molecular surveillance of the circulating DENV strains across the country for prompt identification of emerging strains and novel mutants; gain insights into the formulation of dengue vaccines and develop a clearer understanding of the molecular basis of immune evasion, disease epidemiology and pathogenesis.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"135-142"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haematological parameters as predictors of severe dengue: A study from northern districts of West Bengal, India.","authors":"Sudipta K Roy, Bappaditya Ghosh, Ayan Chakraborty, Santanu Hazra, Bidyut K Goswami, Soumen Bhattacharjee","doi":"10.4103/JVBD.JVBD_119_24","DOIUrl":"10.4103/JVBD.JVBD_119_24","url":null,"abstract":"<p><strong>Background objectives: </strong>A hike in dengue cases was recorded in last two years, resulting from both single and multiple-serotypes of dengue virus (DENV) and secondary infections, culminating in significant hospitalizations and deaths in India. This study focuses on evaluating symptomatic and haematological parameters in acute dengue patients of the northern part of West Bengal to predict disease severity early on and to analyze the correlation between circulating DENV serotypes with severity.</p><p><strong>Methods: </strong>Dengue patients (N=540) diagnosed as NS1 positives were categorized into 13.7% severe DHF (N=74) and 86.3% mild DF (N=466) and prediction of risk was done using logistic regression. DENV RNA was isolated from blood, converted to cDNA, and detected/serotyped via RT-qPCR by using DENV specific primers.</p><p><strong>Results: </strong>Only 14.48% (N=11) patients showed single serotypic (DENV2 or DENV3) infection of dengue. In contrast, multi-serotypic infections (N=65) with the prevalence of DENV-2 and DENV-3 co-infections were found among the dengue patients, affecting severe changes in the most critical haematological parameters such as haematocrit and platelet count. The multivariate binary logistic regression model revealed that only six parameters viz., age (p=0.032), presence of joint pain (p=0.015), Haemoglobin level (p<0.001), total RBC count (p=0.024), total WBC count (p=0.003), lymphocyte% (p=0.019) were found to be significantly associated with the risk of DHF.</p><p><strong>Interpretation conclusion: </strong>Most prevalent DENV-2 and DENV-3 infections significantly impact haematocrit and platelet counts in the study region. Our prediction model, incorporating age, joint pain, haemoglobin, RBC, WBC, and lymphocyte, may effectively predict dengue severity.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"218-225"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142786083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dengue fever complicated with bilateral Psoas hematoma and superadded infection: A case report.","authors":"Nonita Thockchom, Rajat Sharma, Prasan Kumar Panda, Avneet Kumar Gupta","doi":"10.4103/JVBD.JVBD_193_23","DOIUrl":"10.4103/JVBD.JVBD_193_23","url":null,"abstract":"<p><p>Dengue hemorrhagic fever (DHF) typically presents with various bleeding manifestations such as epistaxis, gum bleeding, and gastrointestinal bleeding. However, spontaneous large muscle hematoma formation is a rare complication. This case report discusses a patient with DHF who developed bilateral psoas muscle hematomas, a very uncommon presentation. The patient experienced acute abdominal pain and was diagnosed with psoas muscle hematomas complicated by bacterial infection. Conservative treatment, including fluid management, blood transfusions, and antibiotics, led to the patient's full recovery. This case highlights the importance of suspecting muscle hematomas in DHF patients who present with sudden abdominal or flank pain, especially in the context of dropping hemoglobin and platelet counts. Imaging techniques such as ultrasonography and CT scans are critical for diagnosis. Early diagnosis, close monitoring, and appropriate conservative management are essential for preventing serious outcomes. Prompt treatment of any secondary infections is crucial for patient recovery. This case report reminds clinicians to consider a rare complication.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"242-247"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical evaluation of AYUSH-SL in patients receiving mass drug administration for treatment of chronic inflammatory lymphedema: A doubleblind placebo-controlled multicentric study.","authors":"Achintya Mitra, Gurucharan Bhuyan, C Muralikrishna, S M Naser, K K Ratha, G Babu, B Venkateswarlu, Sujata Dhoke, Chiranjib Bagchi, Renu Singh, Arunabh Tripathi, Rakesh Rana, B S Sharma, Shruti Khanduri, Bharti Gupta, Bcs Rao, Adarsh Kumar, M M Padhi, N Srikanth, K S Dhiman, Santanu K Tripathi","doi":"10.4103/JVBD.JVBD_61_24","DOIUrl":"10.4103/JVBD.JVBD_61_24","url":null,"abstract":"<p><strong>Background objectives: </strong>A 2.5-year placebo-controlled double-blind trial was conducted to investigate the safety and efficacy of AYUSH-SL, a poly-herbal ayurvedic formulation on filarial lymphedema in different endemic areas of India. Lymphatic filariasis (LF) is caused by parasitic nematodes from Wuchereria bancrofti, Brugia malayi, or B. timori that are transmitted through mosquitoes. In Ayurveda, LF has been elaborately narrated under the heading Shlipada and literature also includes detailed therapeutic measures.</p><p><strong>Methods: </strong>The multicenter, prospective, parallel group interventional study in which 180 participants were recruited within the duration through competitive enrollment. Diagnosed cases of Grade I and Grade II filarial lymphedema of Grade I and Grade II (lower extremities) were included in the trial. The study group was treated with mass drug administration and AYUSH-SL or its placebo tablet.</p><p><strong>Results: </strong>The control group had received mass drug administration and a matching placebo. The primary outcome measure was the reduction in edema calculated for analysis by percentage reduction from baseline at the 4 th , 12 th and 24 th week. Secondary outcome measures included improved quality of life (QoL), which was assessed using the Lymphatic Filariasis Specific QoL Questionnaire, and prevention of recurrence of acute episodes, which was evaluated by investigating the presence and severity of episodes in the past four weeks. The water displacement method for the evaluation of the efficacy of the intervention was shown to be highly significant compared to the baseline value (right leg; 3071.60±970.482, 2828.40±829.339, p<0.001and left leg; 3158.69±1136.391, 2890.73±1077.475, p<0.001).</p><p><strong>Interpretation conclusion: </strong>There was significant improvement of Quality of Life in the LF QoL Questionnaire (p<0.001) at each follow-up visit in both groups. Safety estimations on hematologic and biochemical parameters were within limits and or changes were not significant. The results revealed that AYUSH-SL is safe and effective for lymphatic filariasis due to its comprehensive anti-inflammatory, antimicrobial, and anti-allergic activities.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"202-210"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142786078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of artificial intelligence for quantifying Plasmodium berghei in blood samples of infected mice.","authors":"Noha Talal Zelai","doi":"10.4103/JVBD.JVBD_86_24","DOIUrl":"10.4103/JVBD.JVBD_86_24","url":null,"abstract":"<p><strong>Background objectives: </strong>In malaria infection, quantifying blood parasitemia is a critical step for evaluating the severity of the disease. This has generally been conducted manually, and thus its accuracy depends on technician expertise. There is an urgent need for an automated technique to overcome manual errors. The aim of this study was to find an alternative method for counting malaria blood parasitemia.</p><p><strong>Methods: </strong>This study evaluated the accuracy of automated counting using QuPath compared to manual counting. GraphPad Kappa evaluated agreement between high and low parasitemia in both counting methods using Cohen's test.</p><p><strong>Results: </strong>QuPath was revealed to be a promising method that has fair agreement and no statistically significant differences compared to manual counting.</p><p><strong>Interpretation conclusion: </strong>Automated quantification is suggested to be a time and effort-saving technique and therefore is a worthwhile alternative to manual counting.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"233-236"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142983802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reworking the treatment of Indian Post kala-azar dermal leishmaniasis: A two-step therapy.","authors":"Sushruta Kathuria, Yugansh Gautam, Niti Khunger, Shruti Sharma, Ruchi Singh","doi":"10.4103/JVBD.JVBD_205_24","DOIUrl":"10.4103/JVBD.JVBD_205_24","url":null,"abstract":"<p><p>In the current scenario, treatment of Post kala-azar dermal leishmaniasis (PKDL) is intravenous liposomal amphotericin B or oral miltefosine. Over the years, there has been a gradual decline in the efficacy of miltefosine and a rise in permanent loss of vision. Moreover, in non-endemic states of India, miltefosine is not freely available. In view of this, we attempted a two-step regimen of liposomal amphotericin B and itraconazole to treat two patients of PKDL diagnosed on histopathology as well as PCR. We found this treatment to be highly effective with complete recovery.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"248-251"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accelerating the fight towards malaria elimination: Bridging gaps to achieve health equity in India.","authors":"Vani H Chalageri, B M Shrinivasa, N Sujith Nath, Prerana Nandish, Anup Anvikar","doi":"10.4103/JVBD.JVBD_92_24","DOIUrl":"10.4103/JVBD.JVBD_92_24","url":null,"abstract":"<p><p>Malaria continues to remain a serious threat to public health, especially in regions with socio-economic and healthcare disparities. The work attempts to contextualize the current scenario of malaria transmission, the advancement made towards its elimination and the multi-dimensional strategies that may be required to overcome cultural and regional barriers; with a focus on India's goal to eliminate malaria by 2030. The epidemiological spread of malaria across the country is nuanced; wherein an overall reduction of malaria cases recorded over the years (signifying success) could be juxtaposed with more concentration of cases in certain regions. These areas with higher transmission rates are majorly populated by vulnerable social categories like communities living in and near isolated areas, forests, and mountainous regions. This disproportionate distribution signifies the need for focused interventions that take into account localised cultural contexts. Obstacles like drug-resistant strains of parasites, insecticide resistance being developed by vectors and the limitations of existing diagnostic tools are also discussed in the context of socio-demographic changes like urbanization and migration. As India is moving towards elimination phase, health equity has been identified as a key concern. Ensuring equitable access to diagnostic tools, curative facilities and preventive measures becomes key for malaria elimination. In addition to a strong healthcare system, community level involvement engendering community ownership is put forth as a key factor for the success of interventions. Opportunities to improve these efforts through the incorporation of cutting-edge technology, like drone surveillance for vector control and artificial intelligence for diagnosis and rapid identification and response to outbreak have also been brought to the fore. This work emphasizes the significance of an equity-focused approach to malaria elimination, integrating innovative tools and engendering community level cooperation.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"129-134"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current prospects of green-metallic nanoparticles in mosquito control: A brief review.","authors":"Monalisa Pramanik, Priya Roy","doi":"10.4103/JVBD.JVBD_17_24","DOIUrl":"10.4103/JVBD.JVBD_17_24","url":null,"abstract":"<p><p>Mosquitoes (Diptera: Culicidae) transmit many pathogens and parasites such as viruses, bacteria, protozoans and nematodes, which cause serious diseases such as malaria, dengue, yellow fever and chikungunya fever, encephalitis and filariasis. Traditionally, control of these mosquitoes has relied on the use of several chemical insecticides. These insecticides have been used to control various life stages of mosquitoes, but some of these insecticides are causing harm to the environment, human, plants and animals which in turn cause environmental pollution. Presently, nanoparticles are thought to be used as an effective insecticide. Most of the nanoparticles having insecticidal properties are prepared through green synthesis method, where extracts from plants, fungi, bacteria, and even dead insects have been efficaciously employed to decrease or kill mosquito population. Biological and green synthesis methods have resulted in the production of less toxic or nontoxic and sustainable nanoparticles for further application in mosquito control. The evaluation of green chemistry or biological techniques for synthesizing metal NPs from plant extracts and other biological organisms has drawn the attention of many researchers. This review explores the usefulness of green synthesized metal nanoparticles on larvae, pupae and adults of mosquitoes.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"143-153"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141902189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demographic trend in dengue infection.","authors":"Raja Rajeswari, Radhika Raman, N P Nivek, R Syed Rasheed, R D Niranjhana Raajasri","doi":"10.4103/JVBD.JVBD_71_24","DOIUrl":"10.4103/JVBD.JVBD_71_24","url":null,"abstract":"<p><strong>Background objectives: </strong>Dengue fever is one of the most common causes of undifferentiated tropical fevers in hospitalized children across India with the highest recorded morbidity and mortality in children less than 15 years of age. Although common, there is still a knowledge gap regarding its epidemiological factors. The aim of this work was to study the clinical profile and demographic trend over the past 5 years in children with confirmed dengue infection.</p><p><strong>Methods: </strong>This was an observational study of children admitted as in-patients over the past 5 years and diagnosed with dengue infection by serology. Categorical data were presented as percentages. Data regarding rainfall was collected from rainfall statistics from the Indian Meteorological department and correlated based on the T-test. The incidence of dengue infection in COVID-19 predominant years was analyzed using the correlation plot and trend of severe dengue infection over the years was noted by a line plot.</p><p><strong>Results: </strong>The study showed a positive correlation between rainfall and an increase in the incidence of cases. There were relatively reduced number of cases during COVID-19 which was interpreted from the correlation plot. The line plot determined the trend of severity of presentation and more severe cases presented in the years 2019, 2021 and 2022.</p><p><strong>Interpretation conclusion: </strong>Other than the pathophysiology, studies to understand the change in the severity of clinical presentation every year could help in augmenting vector control measures.</p>","PeriodicalId":17660,"journal":{"name":"Journal of Vector Borne Diseases","volume":" ","pages":"237-241"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141902190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}