Konuralp Tıp Dergisi最新文献

{"title":"Investigation of Serum Folate-Receptor-1 Levels in Patients with Non-Small Cell Lung Cancer","authors":"A. Çelikkol, E. Şeber, S. Güzel, A. Yolcu, T. Yetişyiğit, A. Yılmaz","doi":"10.18521/ktd.1165651","DOIUrl":"https://doi.org/10.18521/ktd.1165651","url":null,"abstract":"Objective: Histopathological overexpression of folate receptor-1 (FOLR1) involved in folate transport in cell growth has been reported in various cancers. Increased serum FOLR1(sFOLR1) has also been reported in epithelial ovarian cancer. The aim was to investigate sFOLR1 levels in non-small cell lung cancer (NSCLC) patients and the response prediction of the standard chemotherapy targeting folic acid metabolism. \u0000Method: In this prospective study, sFOLR1 levels were investigated in 30 healthy individuals and 60 patients with stage4 malign metastatic NSCLC before and after standard chemotherapy. The commercial immunoassay (ELISA) kit used for analysis of sFOLR1. Serum carcinoembryonic antigen (CEA), vitamin B12, and folate levels were also investigated. \u0000Result: In NSCLC patients sFOLR1 levels were significantly higher(p","PeriodicalId":174708,"journal":{"name":"Konuralp Tıp Dergisi","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133503470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Health Promoting Lifestyle Habits During Pandemic Period: A cross-sectional study","authors":"Funda Gökgöz Durmaz, F. Cihan","doi":"10.18521/ktd.1160147","DOIUrl":"https://doi.org/10.18521/ktd.1160147","url":null,"abstract":"Objective: The COVID-19 pandemic imposed lifestyle changes. The aim of this study was to evaluate the health-promoting lifestyle habits of individuals who applied to a primary care center during the pandemic period. \u0000Methods: This descriptive and cross-sectional study was conducted with the voluntary participation of 524 individuals. The data was collected through a research questionnaire form and the Health Promoting Lifestyle Scale (HPLS). \u0000Results: Women accounted for 58.2% (n=305) of all participants, 45.2% of them (n=237) had chronic disease and 32.1% (n=168) were smoking. Mean age was 41.26±14.28 (min:18, max:75) years old. Among these participants, %53.2 had equal income to their expenses (n=279), 52.3% experienced sleep pattern changes (n=274), 35.7% had COVID-19 disease and 66.6% vaccinated for COVID-19. The mean HPLS score was 162.75±8.10 points. Interpersonal relationships, stress management and total HPLS scores were higher in women (p","PeriodicalId":174708,"journal":{"name":"Konuralp Tıp Dergisi","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134267850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ROMATOİD ARTRİTTE GÖZ BULGULARI: FARKLI OLGULAR VE ORANLARI","authors":"Yasemin Fatma Çeti̇nkaya","doi":"10.18521/ktd.1114791","DOIUrl":"https://doi.org/10.18521/ktd.1114791","url":null,"abstract":"Objective: The aim of this study is to determine the accompanying ocular findings, frequency and to examine the complications in Rheumatoid Arthritis (RA) patients. \u0000Method: Medical records of Rheumatoid Arthritis patients who were consulted with the eye clinic between 2017 and 2022, were retrospectively reviewed. Demographic features, eye examination findings, and detected eye diseases were noted. \u0000Results: The records of 23840 Rheumatoid Arthritis and related patients who were consulted with the Eye Clinic were reviewed. From these patient records, 2691 patients, who were especially diagnosed with seropositive Rheumatoid Arthritis, were evaluated in detail within the scope of the study. Ophthalmological examination findings obtained from the records were examined. In particular, anterior segment biomicroscopy, Schirmer test, tear break-up time (BUT) and fundus examination was evaluated. 2067 of the patients were female and 624 were male. And the mean age was examined. When the average age is examined; patients aged 41-65 years were the most common (1795 patients (1374 women, 421 men)). The most common sign of ocular involvement was a dry eye(%25.97). Less frequently, episcleritis was found in 4.57% of patients, and scleritis was found in 1.37%. There were no patients with posterior or necrotizing scleritis among the patients examined. In addition, posterior scleritis of the cornea, scleromalacia, or retinal vasculitis were not detected in our patients. \u0000Conclusion: Rheumatoid Arthritis is a disease that can progress with extra-articular findings and may even appear as the first finding. Ocular findings may accompany the disease at a considerable rate. It can also affect the prognosis of the disease with the right perspective.","PeriodicalId":174708,"journal":{"name":"Konuralp Tıp Dergisi","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131722472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Turkish Validity and Reliability of the Satisfaction with Simulation Experience Scale","authors":"Hilal Tüzer, V. Kocatepe, Tuba Yılmazer, B. Inkaya, Vesile Ünver, T. Levett-Jones","doi":"10.18521/ktd.1086313","DOIUrl":"https://doi.org/10.18521/ktd.1086313","url":null,"abstract":"Objective: Research on simulation-based experience focuses primarily on the student's level of knowledge, skills, self-confidence, and satisfaction. There is only one scale in Turkish that can be used to measure satisfaction with the simulation experience. The aim of this study was to establish the validity and reliability of the Turkish version of the Satisfaction with Simulation Experience Scale (SSES). \u0000Methods: The study sample consisted of 130 nursing students from two universities. Data were collected using a student information form, the Turkish version of the Satisfaction with Simulation Experience Scale (SSES-TR) and the Scale of Student Satisfaction and Confidence in Learning (SSSCL). The original SSES was translated into Turkish. Thirteen academics, who were experts in nursing and simulation, were consulted for content validity. Expert feedback was collected in a form to determine the content validity ratio using Lawshe's technique. The Turkish adaptation of the SSES was performed by four linguists to ensure linguistic validity. The correlation between the SSES-TR and SSSCL was determined using concurrent validity and Pearson’s Correlation. Internal consistency tests were used to test reliability. The SSES-TR was administered to 35 students as a test-retest with an interval of two weeks to determine its consistency across time. \u0000Results: The SSES-TR had a Cronbach’s alpha (α) of 0.928. The correlation between SSES-TR items and total and subscale scores ranged from 0.492 to 0.749. Test-retest reliability coefficients showed that the SSES-TR total score and subscale scores were compatible. \u0000Conclusion: The SSES-TR is a reliable and valid measure that can be used to assess nursing students’ satisfaction with simulation-based experience.","PeriodicalId":174708,"journal":{"name":"Konuralp Tıp Dergisi","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129229361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short-Term Effect of Kinesio Taping On Neck Pain and Disability in Patients with Loss of Cervical Lordosis: A Randomized Controlled Study","authors":"E. Tastaban","doi":"10.18521/ktd.1160513","DOIUrl":"https://doi.org/10.18521/ktd.1160513","url":null,"abstract":"Objective: The patients with loss of cervical lordosis have weakened neck extensors. This study aimed to investigate the effect of Kinesio taping, applied to the cervical extensors, on neck pain and disability in patients with loss of cervical lordosis. Methods: A total of 111 patients with neck pain due to loss of cervical lordosis completed the study (54 Kinesio tape group, 57 control group). All patients were given paracetamol 1500 mg/day for four days. Additionally, the Kinesio tape group received one session of Kinesio taping treatment. Neck pain intensity was assessed using the Visual Analogue Scale, and neck disability was evaluated using the Neck Disability Index. The measurement points were baseline and day 4. Results: Visual Analogue Scale and Neck Disability Index scores were similar at baseline. Statistically significant improvements in the levels of pain and disability were observed in both groups; however, there was further change in the Kinesio tape group (p","PeriodicalId":174708,"journal":{"name":"Konuralp Tıp Dergisi","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124022413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The clinical correlations of fatigue in patients with sarcoidosis","authors":"Pınar Yıldız Gülhan, Ege Güleç Balbay, M. Erçelik, A. Annakkaya, P. Arbak, Özlem Özdemir Kumbasar","doi":"10.18521/ktd.1084080","DOIUrl":"https://doi.org/10.18521/ktd.1084080","url":null,"abstract":"Introduction: Fatigue is considered a frequent and characteristic feature of sarcoidosis. This study was designed to determine the prevalence of fatigue in patients with sarcoidosis and to determine its potential clinical correlations in relation to symptom severity. \u0000Methods: A total of 56 sarcoidosis patients were included. Data on patient demographics, anthropometrics, disease characteristics, pulmonary function tests, 6-min walking distance (6MWD), blood biochemistry and hemogram findings were retrieved from hospital records. Psychometric instruments involved fatigue assessment scale (FAS), Beck Depression Inventory (BDI) and Short Form-36 (SF-36) for health-related QOL (HRQOL). \u0000Results: Mean±SD patient age was 50.9±11.9 years. Of 56 patients, 44 were females and 12 were males. When compared to FAS score","PeriodicalId":174708,"journal":{"name":"Konuralp Tıp Dergisi","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115685437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acil Servise Başvuran Metil Alkol Zehirlenmelerinin Geriye Dönük Analizi","authors":"Taner Şahin, Oğuzhan Bol, Mukerrem Altuntas","doi":"10.18521/ktd.1147742","DOIUrl":"https://doi.org/10.18521/ktd.1147742","url":null,"abstract":"Objective: Methyl alcohol poisoning remains a significant cause of mortality and morbidity. This poisoning is still one of the important reasons for admission to emergency services. We aimed to examine the admission complaints, laboratory findings, treatment methods, clinical outcomes and examine the factors affecting the mortality of patients diagnosed with methyl alcohol poisoning in the emergency department. \u0000Methods: In this retrospective descriptive study, we analysed the patients who were considered to be diagnosed with methyl alcohol intoxication among those who came to our emergency department due to alcohol intoxication from June 1, 2018 to June 1, 2020. \u0000Results: The study included 20 (4.86%) individuals with methyl alcohol poisoning among 411 people who presented to the emergency department due to ethyl and methyl alcohol intake and resulting effects.The mean age of the patients was 47.35±14.2 years and 85% (n=17/20) were male. Upon reviewing the patients' admission symptoms, 70% were observed to have visual problems, 60% complaints of vomiting, 45% shortness of breath, and 40% changes in consciousness. In the study, it was revealed that 18.2%(n=2/11) females and 81.8%(n=9/11) males died, and the mortality rate was calculated as 55%(n=11/20). \u0000Conclusions: The presence of visual problems, hypotension, and coma in clinical findings, high anion gap metabolic acidosis, marked osmolar gap, an increase in lactate level, and hyperglycemia in laboratory findings may be the early signs of mortality in patients with methyl alcohol poisoning. Therefore, patients with these signs should be followed up more closely and treated.","PeriodicalId":174708,"journal":{"name":"Konuralp Tıp Dergisi","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116199581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerrahi Tedavi uygulanmış Ayak Bileği Kırıklarının Klinik, Radyolojik ve Fonksiyonel Sonuçlarının Değerlendirilmesi","authors":"C. Güler, Z. Karaduman, Zafer Orhan, Şafak Orhan, Yalçın Turhan, Mehmet Arıcan, Ozan Turhal","doi":"10.18521/ktd.1113371","DOIUrl":"https://doi.org/10.18521/ktd.1113371","url":null,"abstract":"Amaç \u0000Ayak bileği vücudun yürüme fonksiyonunda önemli bir eklemdir. Deplase ve stabil olmayan kırıkların ve eklem uyumunun konservatif yöntemlerle sağlanamadığı durumlarda cerrahi tedavi gerekir. Cerrahi tedavinin temel amacı, normal bir tibiotalar ilişki için talusun ayak bileği içindeki anatomik pozisyonunu sağlamaktır. Ayak bileği kırıklarında tedavi sonuçlarını etkileyen en önemli faktörler kırık tipi, malleol kırığı sayısı, redüksiyonun yeterliliği ve hastanın yaşıdır. \u0000Yöntem \u0000Ocak 2006-Ekim 2015 tarihleri arasında polikliniğimize başvuran, ayak bileği kırığı tanısı alan ve cerrahi tedavi uygulanan 73 hasta retrospektif olarak klinik, fonksiyonel ve radyolojik olarak değerlendirildi ve sağlam ayak bileği ile karşılaştırıldı. \u0000Bulgular \u0000Ameliyat olan hastalardan; 34'ünde bimalleol kırığı (%46.58), 8'inde (%10.96) trimalleol kırığı, 14'ünde lateral malleol kırığı (%19.18), 13'ünde medial malleol kırığı (%17.81), 1’inde posterior malleol kırığı ile birlikte ayak bileği çıkığı (%1.37) ve 1’inde de medial malleol kırığı ile birlikte arka malleol kırığı vardı (%1.37). Lauge Hansen sınıflamasına göre en sık SER (Supinasyon Eksternal Rotasyon) kırık tipi (14 olgu) (%19.18), ardından ikinci en sık PER (Pronasyon Eksternal Rotasyon) kırık tipi (14 olgu) (%19.18) idi. belirlendi. Supinasyon Addüksiyon tipi 10 vaka (% 13.70) ve PAP (Pronasyon Abdüksiyon) tipi 7 vaka (% 9.59) vardı. Danis - Weber sınıflamasına göre en sık Tip C (21 vaka) (% 52.50) ve ikinci en sık Tip B (14 vaka) (% 35,00) idi. Kaynama süresi kırık tipine göre incelendiğinde istatistiksel olarak anlamlı farklılık gözlenmedi (p=0,064). Her 3 skorlama sistemine göre istatistiksel olarak anlamlı olmasa da ameliyat öncesi bekleme süresinin uzaması ile kötü sonuç oranı arttı. Weber'e göre mükemmel iyileşme 18-42 yaş grubunda istatistiksel olarak anlamlı derecede yüksek bulundu (p=0,029) ve Weber'e göre bimalleolar kırıklarda kötü sonuç anlamlı olarak daha yüksek bulundu. Weber protokolüne göre lateral malleol kırığında mükemmel sonuç anlamlı olarak daha yüksek bulundu. Posterior malleol saptanan trimalleolar kırığı olan hastaların AOFAS (Amerikan Ortopedik Ayak ve Ayak Bileği Derneği) skoru 92.11; Buradan posterior malleol stabilizasyonunun ayak bileği fonksiyonel skorunu olumlu etkilediği belirlendi. \u0000Sonuç \u0000Ayak bileği kırıklarında cerrahi tedavi uygulanacaksa fibula uzunluğu sağlanmalı, eklem yüzeyinin anatomik olarak küçültülmesi amacıyla rijit iç tespit yapılmalı ve ayak bileği hareketlerine erken başlanmalıdır.","PeriodicalId":174708,"journal":{"name":"Konuralp Tıp Dergisi","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133671245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aile Hekimliği Uzmanlık Eğitiminde Simülasyon Temelli Eğitim Yaklaşımlarının Değerlendirilmesi","authors":"Merve Altintop, Kerem Uzun, Serdar Karakullukçu, Cüneyt Ardıç","doi":"10.18521/ktd.1128251","DOIUrl":"https://doi.org/10.18521/ktd.1128251","url":null,"abstract":"Amaç: Etkinliğimizin amacı TUKMOS (Tıpta Uzmanlık Kurulu Müfredat Oluşturma ve Standart Belirleme Sistemi) Aile Hekimliği uzmanlık eğitimi müfredatında yer alan girişimsel yetkinlikleri simülasyon merkezimizdeki imkanlar kullanılarak Aile Hekimliği Asistanlarına sunularak beceri düzeylerinin arttırılmasıdır. \u0000Gereç ve Yöntem: TÜBİTAK-BİDEP 2237 Destekleme Programı doğrultusunda planladığımız ‘RSİM 1. Aile Hekimliği Asistanları Simülayon Eğitimi’ projesini toplam 32 Aile Hekimi asistanın katılımıyla gerçekleştirdik. Tüm katılımcılara eğitim ön test-son test uygulandı. Ayrıca 34 sorudan oluşan simülasyon eğitimi geri bildirim anketi yapılmıştır. \u0000Bulgular: Eğitime katılanların %71,9’u(n:23) kadın, %56,2’si(n:18) üniversite hastanesinde çalışmaktaydı. Hekimlikte geçen aktif çalışma süresi 2 yıldan az olanlar %59,4 (n:19), asistanlık eğitim süresi 2-3 yıl olanlar %53,1 (n:17) idi. Katılımcıların ön test ve son test ortalama puanları karşılaştırıldığında arasındaki fark istatistiksel olarak anlamlı bulundu(p","PeriodicalId":174708,"journal":{"name":"Konuralp Tıp Dergisi","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132756017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sağlık Öğrencileri İçin Ruh Sağlığı Okuryazarlık Ölçeğinin Türkçeye Uyarlanması: Geçerlik ve Güvenirlik Çalışması","authors":"Seher PALANBEK YAVAŞ, Caner Baysan, A. Önal, Özkan Ayvaz","doi":"10.18521/ktd.1113580","DOIUrl":"https://doi.org/10.18521/ktd.1113580","url":null,"abstract":"Amaç: Bu çalışmada, Sağlık Öğrencileri için Ruh Sağlığı Okuryazarlık Ölçeğinin (RSOÖ-SÖ) Türkçe uyarlaması için geçerlilik ve güvenilirlik yapılması amaçlanmıştır. \u0000Method: Çalışma örneklemi 18-27 yaş arasında İstanbul Tıp Fakültesinde öğrenim gören 275 kişiden oluşmaktadır. RSOÖ-SÖ ölçeği, Ruhsal Hastalıklara Yönelik İnanç Ölçeği (RHYİÖ) ve Pozitif Mental Sağlık Ölçeğini (PMSÖ) veri toplamada kullanılmıştır. Dil uyarlaması için çeviri, geri çeviri, uzman görüşleri ve pilot uygulama yapılmıştır. Geçerlik için kapsam geçerlilik indeksi, doğrulayıcı faktör analizi ve güvenilirliği test etmek için Cronbach alfa analizi, test-tekrar test yöntemi kullanılmıştır. \u0000Bulgular: Ölçeğin kapsam geçerlilik indeksi 0.99 ve doğrulayıcı faktör analizine göre madde yükleri 0.38-0.94 olduğu bulunmuştur. Cronbach alfa katsayısı tüm ölçek için 0.79, beş alt boyutu için ise 0.60-0.89 arasında olduğu belirlenmiştir. Eşdeğer ölçüt geçerliliğinde RHYİÖ ile negatif yönlü zayıf korelasyon (r=-0.391, p","PeriodicalId":174708,"journal":{"name":"Konuralp Tıp Dergisi","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122625140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}