Acil Servise Başvuran Metil Alkol Zehirlenmelerinin Geriye Dönük Analizi

Taner Şahin, Oğuzhan Bol, Mukerrem Altuntas
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Abstract

Objective: Methyl alcohol poisoning remains a significant cause of mortality and morbidity. This poisoning is still one of the important reasons for admission to emergency services. We aimed to examine the admission complaints, laboratory findings, treatment methods, clinical outcomes and examine the factors affecting the mortality of patients diagnosed with methyl alcohol poisoning in the emergency department. Methods: In this retrospective descriptive study, we analysed the patients who were considered to be diagnosed with methyl alcohol intoxication among those who came to our emergency department due to alcohol intoxication from June 1, 2018 to June 1, 2020. Results: The study included 20 (4.86%) individuals with methyl alcohol poisoning among 411 people who presented to the emergency department due to ethyl and methyl alcohol intake and resulting effects.The mean age of the patients was 47.35±14.2 years and 85% (n=17/20) were male. Upon reviewing the patients' admission symptoms, 70% were observed to have visual problems, 60% complaints of vomiting, 45% shortness of breath, and 40% changes in consciousness. In the study, it was revealed that 18.2%(n=2/11) females and 81.8%(n=9/11) males died, and the mortality rate was calculated as 55%(n=11/20). Conclusions: The presence of visual problems, hypotension, and coma in clinical findings, high anion gap metabolic acidosis, marked osmolar gap, an increase in lactate level, and hyperglycemia in laboratory findings may be the early signs of mortality in patients with methyl alcohol poisoning. Therefore, patients with these signs should be followed up more closely and treated.
目的:甲醇中毒仍然是死亡率和发病率的重要原因。这种中毒仍然是入院急救服务的重要原因之一。我们旨在探讨急诊诊断为甲醇中毒患者的入院投诉、实验室检查、治疗方法、临床结果以及影响死亡的因素。方法:在这项回顾性描述性研究中,我们分析了2018年6月1日至2020年6月1日因酒精中毒来我急诊科就诊的患者中被认为诊断为甲醇中毒的患者。结果:在411名因摄入乙基和甲醇以及由此产生的影响而到急诊室就诊的患者中,该研究包括20名(4.86%)甲醇中毒患者。患者平均年龄47.35±14.2岁,男性占85% (n=17/20)。在回顾患者的入院症状时,观察到70%的患者有视力问题,60%的患者有呕吐,45%的患者呼吸急促,40%的患者意识改变。研究结果显示,女性死亡18.2%(n=2/11),男性死亡81.8%(n=9/11),计算死亡率为55%(n=11/20)。结论:临床表现为视力问题、低血压和昏迷、高阴离子间隙代谢性酸中毒、明显的渗透压间隙、乳酸水平升高和实验室表现为高血糖可能是甲醇中毒患者死亡的早期体征。因此,有这些体征的患者应更密切地随访和治疗。
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