Journal of the Turkish German Gynecological Association最新文献

{"title":"Erratum.","authors":"","doi":"10.4274/jtgga.galenos.2025.e004","DOIUrl":"10.4274/jtgga.galenos.2025.e004","url":null,"abstract":"","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":"26 1","pages":"71"},"PeriodicalIF":1.2,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143615813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.4274/jtgga.galenos.2025.e005","DOIUrl":"10.4274/jtgga.galenos.2025.e005","url":null,"abstract":"","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":"26 1","pages":"72"},"PeriodicalIF":1.2,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143615816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Manual reduction in conjunction with Arabin pessary to reduce first trimester urinary retention relapse.","authors":"Paola Algeri, Federico Licciardi, Nunzia Mastrocola, Laura Imbruglia, Greta Cagninelli, Patrizia D'Oria","doi":"10.4274/jtgga.galenos.2024.2024-4-2","DOIUrl":"10.4274/jtgga.galenos.2024.2024-4-2","url":null,"abstract":"","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":"26 1","pages":"65-67"},"PeriodicalIF":1.2,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143615827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of non-functioning pituitary adenomas on pregnancy.","authors":"Özge Baş Aksu, Özgür Demir, Asena Gökçay Canpolat, Demet Çorapçıoğlu","doi":"10.4274/jtgga.galenos.2024.2024-6-1","DOIUrl":"10.4274/jtgga.galenos.2024.2024-6-1","url":null,"abstract":"<p><strong>Objective: </strong>Non-functioning pituitary adenomas (NFPAs) are a group of hormonally inactive adenomas. The aim of this study was to investigate the possible effects of NFPAs on pregnancy.</p><p><strong>Material and methods: </strong>Thirty patients with NFPAs and without hormone deficiency or excess were included. We retrospectively evaluated anterior pituitary hormone levels, follow-up periods, pituitary imaging findings, symptoms associated with adenoma size increase during pregnancy, adverse pregnancy outcomes, delivery procedures, pregnancy week at delivery, birth weight, and lactation duration.</p><p><strong>Results: </strong>The mean age of the patients was 41.26±9.06 years, and the mean follow-up after diagnosis was 92.8 months. Seven were diagnosed with macroadenomas (defined as the largest diameter >10 mm) and 23 had microadenomas. There were 92 pregnancies in total. The incidence of nausea-vomiting and visual impairment during pregnancy were more common in the macroadenoma group (p=0.016 and p=0.042, respectively). Spontaneous pregnancy rates were high. The patients with NFPAs did not have an increased risk of pregnancy-related complications compared to the general population, and there were no obvious negative effects on fetal development or lactation. NFPAs were not associated with an increased cesarean section rate.</p><p><strong>Conclusion: </strong>These findings suggest that NFPAs, even macroadenomatous NFPAs, have no negative effects on pregnancy outcomes, fetal development, or lactation.</p>","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":"26 1","pages":"20-25"},"PeriodicalIF":1.2,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143615869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.4274/jtgga.galenos.2025.e006","DOIUrl":"10.4274/jtgga.galenos.2025.e006","url":null,"abstract":"","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":"26 1","pages":"72"},"PeriodicalIF":1.2,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143615818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.4274/jtgga.galenos.2025.e003","DOIUrl":"10.4274/jtgga.galenos.2025.e003","url":null,"abstract":"","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":"26 1","pages":"71"},"PeriodicalIF":1.2,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143615811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of <i>TNP1</i> and <i>PRM1</i> gene expression in male infertility patients with low or high sperm DNA fragmentation.","authors":"Yavuz Şahin, Elif Sibel Aslan, Süleyman Aktuna, Volkan Baltacı","doi":"10.4274/jtgga.galenos.2024.2024-5-3","DOIUrl":"10.4274/jtgga.galenos.2024.2024-5-3","url":null,"abstract":"<p><strong>Objective: </strong>The transition nuclear protein 1 (<i>TNP1</i>) gene is a member of the TNP family and is abundantly expressed during spermatogenesis. Protamine 1 (<i>PRM1</i>), another sperm nuclear protein, is abundant in many species. The present study aimed to evaluate transition nuclear protein 1 (<i>TNP1</i>) and protamine 1 (<i>PRM1</i>) gene expression in infertile male patients with low and high sperm DNA fragmentation (SDF).</p><p><strong>Material and methods: </strong>Semen samples (n=100) were obtained from male participants undertaking treatment with intracytoplasmic sperm injection. The expression levels of <i>TNP1</i> and PRM1 were measured using real-time quantitative polymerase chain reaction. The data were compared with statistical tests, (independent samples T- or Mann-Whitney U) as appropriate. A p<0.05 was considered significant.</p><p><strong>Results: </strong>Patients with low-SDF exhibited a significantly lower sperm concentration compared to those with high-SDF (p=0.002). There was significant down regulation of <i>TNP1</i> (p=0.036) and <i>PRM1</i> (p=0.04) in patients exhibiting high-SDF levels compared to those with low-SDF levels. A significant moderate positive correlation was observed between the relative expression levels of <i>TNP1</i> and <i>PRM1</i> (r=0.459, p<0.001).</p><p><strong>Conclusion: </strong>In the present study <i>TNP1</i> and <i>PRM1</i> were differentially expressed in male patients being treated for infertility and who had low or high-SDF.</p>","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":"26 1","pages":"7-14"},"PeriodicalIF":1.2,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143615821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative predictors of concurrent endometrial carcinoma in patients with endometrial intraepithelial neoplasia: the role of HALP score and other inflammatory markers.","authors":"Okan Aytekin, Çiğdem Karagöz, Esra Göktaş, Abdurrahman Alp Tokalıoğlu, Gülşah Tiryaki Güner, Yeşim Özkaya Uçar, Fatih Kılıç, Taner Turan","doi":"10.4274/jtgga.galenos.2025.2024-12-5","DOIUrl":"10.4274/jtgga.galenos.2025.2024-12-5","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to identify preoperative factors that predict concurrent endometrial carcinoma in patients with endometrial intraepithelial neoplasia (EIN), focusing on inflammatory markers, such as hemoglobin, albumin, lymphocyte, and platelet (HALP) score, prognostic nutritional index (PNI), the modified systemic inflammatory score (mSIS), clinical characteristics, and imaging findings.</p><p><strong>Material and methods: </strong>A retrospective review was conducted of patients diagnosed with EIN who underwent hysterectomy and bilateral salpingo-oophorectomy between 2019 and 2024. Data collected included demographic details, cancer antigen-125 levels, hematological parameters, HALP score, PNI, mSIS, and preoperative endometrial thickness. Statistical analyses were performed to evaluate the associations between these factors and concurrent endometrial carcinoma.</p><p><strong>Results: </strong>Concurrent endometrial carcinoma was identified in 39 (19.9%) of the total of 196 patients included. Significant predictors included older age (p<0.001), lower platelet count (p<0.001), and endometrial thickness greater than 13 mm (p=0.044). Inflammatory markers such as the HALP score, PNI, and mSIS did not show significant associations. The majority of cases with carcinoma were International Federation of Gynecology and Obstetrics stage IA (76.9%) and grade 1 endometrioid tumors (94.9%).</p><p><strong>Conclusion: </strong>Advanced age, reduced platelet count, and increased endometrial thickness are key predictors of concurrent endometrial carcinoma in patients with EIN. These findings may be useful for improved preoperative risk stratification and inform surgical planning. Further research is needed to explore the role of inflammatory biomarkers in this context.</p>","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":"26 1","pages":"34-40"},"PeriodicalIF":1.2,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143615862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usefulness of delayed primary closure in unplanned caesarean section to reduce surgical site infection in a resource-poor high population country: a randomised controlled trial.","authors":"Jhuma Biswas, Shyamal Dasgupta, Mallika Datta, Poushali Sanyal, Namrata Bhattacharya, Mostafa Kamal","doi":"10.4274/jtgga.galenos.2024.2024-7-1","DOIUrl":"10.4274/jtgga.galenos.2024.2024-7-1","url":null,"abstract":"<p><strong>Objective: </strong>Surgical site infection (SSI) is a common complication, especially following emergency caesarean section (CS) leading to maternal morbidity and prolonged hospital stay. Results are conflicting regarding the ideal method of skin closure after abdominal surgery in clean contaminated and contaminated wound. To compare the outcome of wound health between primary and delayed primary closure (DPC) of skin incision in emergency CS.</p><p><strong>Material and methods: </strong>A total of 70 pregnant women undergoing emergency caesarean deliveries with a history of membrane rupture were randomized into group A (n=40) and group B (n=30). In group A monofilament sutures were placed in skin incision but the wound was left open for daily dressing with normal saline. It was closed by tying the monofilament sutures on fifth day and stitches were removed on seventh day. In group B skin was apposed by a routine primary closure procedure.</p><p><strong>Results: </strong>No patient in group A required secondary wound closure following SSI (p<0.001) and duration of hospital stay was also significantly reduced (p<0.05).</p><p><strong>Conclusion: </strong>This trial demonstrated that DPC is effective in reduction of requirement of secondary stitches due to SSI in emergency CS.</p>","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":"26 1","pages":"1-6"},"PeriodicalIF":1.2,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143615872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.4274/jtgga.galenos.2025.e001","DOIUrl":"10.4274/jtgga.galenos.2025.e001","url":null,"abstract":"","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":"26 1","pages":"70"},"PeriodicalIF":1.2,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143615806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}