Journal of the Turkish German Gynecological Association最新文献

{"title":"What is your diagnosis?","authors":"Mishu Mangla, Ruchira Nautiyal, Neha Dagar","doi":"10.4274/jtgga.galenos.2022.2022-5-3","DOIUrl":"https://doi.org/10.4274/jtgga.galenos.2022.2022-5-3","url":null,"abstract":"A 25-year-old primigravida, was admitted to the antenatal ward at 32 weeks gestation with decreased fetal movements. The patient lived in a remote hilly region and did not go for antenatal checkups because of the non-availability of transport due to the lockdown imposed during the coronavirus pandemic. The patient did not undergo an anomaly scan in the first or second trimester. The present pregnancy was conceived spontaneously, without any history of ovulation induction. There was no history of consanguineous marriage. There was no history of teratogenic drug exposure in the antenatal period. The patient did not have any risk factors for gestational diabetes, body mass index was 22.6 kg/m 2 , and family history was not significant. Blood sugar profile was normal after admission, and during the intrapartum and postpartum periods while hemoglobinA1c was normal at 5.8%. On examination, the fundal height corresponded to 26 weeks, and fetal parts were palpable superficially, suggesting decreased liquor and fetal growth restriction (FGR). The ultrasound showed a single live fetus in breech presentation, corresponding to gestational age 32 weeks with severe FGR, abdominal circumference less than the third centile, biparietal diameter and head circumference at the fifth centile and femur length at the tenth centile with placenta praevia and almost absent liquor. Due to grossly decreased liquor, the radiologist could not comment on fetal anatomy at this gestation. A Doppler study of the umbilical arteries suggested reversed end-diastolic flow with brain sparing effect. Cardiotocography was suggestive of prolonged late decelerations. After discussion with the parents, the patient was taken for lower segment caesarean section because of primigravida with placenta praevia, breech presentation and Stage 4 FGR with high suspicion of fetal acidosis (1).","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7f/c9/JTGGA-23-322.PMC9743352.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10403332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of biacromial and bideltoid distance on shoulder dystocia and birth weight in newborns","authors":"Elif Terzi,&nbsp;Pervin Demir","doi":"10.4274/jtgga.galenos.2022.2022-6-10","DOIUrl":"https://doi.org/10.4274/jtgga.galenos.2022.2022-6-10","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the relationship between neonatal biacromial and bideltoid diameter (BDD), birth weight and shoulder dystocia (SD).</p><p><strong>Material and methods: </strong>This was a prospective observational study conducted on 161 pregnancies who applied to Private Lokman Hekim Hospital for follow-up between February 2021 and August 2021. Maternal height, weight, parity, and presence of SD in the second stage of labor were evaluated in the patients included in the study. The weight, height, head circumference, biacromial and BDD measurements of newborn babies were taken within the first two hours after birth. The primary purpose of the study was to evaluate the relationship between the biacromial and BDD and SD. The secondary purpose of the study was to evaluate the relationship between the biacromial and BDD and macrosomia.</p><p><strong>Results: </strong>The mean age and post-pregnancy body mass index of the participants were 31.3±4.4 years and 29.0±4.0 kg/m2, respectively, and 42.9% (n=69) delivered vaginally. The incidence of macrosomia was 6.8% (n=11) in all women and the incidence of SD was 7.2% (n=5) in women who had vaginal deliveries. The mean biacromial diameter (BAD) was 12.4±1.0 cm and the mean BDD was 18.2±1.7 cm. A correlation rate of 0.373 was found between SD and the BAD, and 0.484 between SD and the BDD. The correlation coefficients between macrosomia and the biacromial and BDD were 0.213 and 0.420, respectively. In cases in which the BDD was ≥21 cm, the sensitivity for SD was 100%, the specificity was 90.63%, and the accuracy was 91.30%. The cut-off point for the BAD was ≥14 cm, and the sensitivity and specificity for SD was 63.64% and 89.33%, respectively. The highest correlation for SD was obtained in cases in which there was a history of SD (0.648).</p><p><strong>Conclusion: </strong>The relationship between neonatal biacromial and BDD, and macrosomia and SD were significant. There was no difference between the correlation values of the two measurements in terms of SD. However, the correlation coefficient of the BDD was greater for macrosomia.</p>","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ba/a2/JTGGA-23-241.PMC9743354.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10746584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awareness, knowledge and attitude toward the relationship between periodontal health and pregnancy outcomes among obstetrician-gynecologist healthcare professionals in Turkey: Results of 11^th Turkish-German Gynecological Association Congress based survey","authors":"Resul Turabi,&nbsp;Ömer Birkan Agrali,&nbsp;Başak Doğan","doi":"10.4274/jtgga.galenos.2022.2021-9-13","DOIUrl":"https://doi.org/10.4274/jtgga.galenos.2022.2021-9-13","url":null,"abstract":"Objective: The aim of this study was to evaluate the knowledge and practice behavior of Turkish obstetrician-gynecologists regarding oral healthcare during pregnancy and the association between periodontal disease and adverse pregnancy outcomes. Material and Methods: A cross-sectional study was conducted on randomly selected Turkish obstetrician-gynecologists using a questionnaire consisting of 26 questions during 11th Turkish-German Gynecological Association Congress. Participation in the survey was voluntary. Results Out of 435 attendees approached, 382 (88%) of the gynecologists at the Congress participated in the written questionnaire. Most of the participants (96.1%) acknowledged a connection between oral health and pregnancy, and 77.5% agreed that periodontal disease may affect the outcome of pregnancy. Moreover, a high proportion of participants were aware of the clinical signs of periodontal diseases, mainly gingival bleeding (92.1%). However, almost 20% of participants thought that dental treatment could be performed safely in the first or last trimester of pregnancy. Only 36.9% of participants recommended guidance on dental examination for their patients during prenatal care. Conclusion: This study demonstrated that Turkish obstetrician-gynecologists have a relatively high degree of knowledge with respect to the relationship between periodontal disease and pregnancy outcomes, but practice behavior was poorly correlated with their knowledge.","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/00/aa/JTGGA-23-275.PMC9743345.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10399156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of the reproductive and oncologic outcomes of fertility-sparing surgery for early-stage cervical cancer","authors":"Farr Nezhat,&nbsp;Hadi Erfani,&nbsp;Camran Nezhat","doi":"10.4274/jtgga.galenos.2022.2022-9-7","DOIUrl":"https://doi.org/10.4274/jtgga.galenos.2022.2022-9-7","url":null,"abstract":"<p><p>In this review, we aim to evaluate the current literature on reproductive and oncologic outcomes after fertility-sparing surgery for early-stage cervical cancer (stage IA1-IB1). This is a systematic review of the existing literature using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) checklist to report on fertility-sparing surgery and its outcomes in early-stage cervical cancer. Outcomes of interest were subsequent clinical pregnancy rate, reproductive outcomes, and cancer recurrence outcomes. Included in this systematic review were 68 studies encompassing 3,592 patients who underwent fertility-sparing surgery. Of these, reproductive outcomes were reported in 1096 pregnancies. The mean clinical pregnancy rate was 53.2%. Those who underwent vaginal radical trachelectomy had the highest clinical pregnancy rate (67.5%). The mean live birth rate was 67.8% in our study. Twenty-one percent of pregnancies after fertility-sparing surgery required assisted reproductive technology. The mean cancer recurrence rate was 3.2%, and the cancer death rate was 0.6% after a median follow-up period of 40.1 months with no statistically significant difference across surgical approaches. Offering fertility-sparing surgery in early-stage cervical cancer is reasonable. Highest clinical pregnancy rate is associated with vaginal radical trachelectomy. Moreover oncologic outcomes of minimally invasive approaches were comparable with abdominal approaches. We encourage detailed preoperative counseling and multidisciplinary approach to achieve best outcomes.</p>","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f3/c1/JTGGA-23-287.PMC9743349.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10403330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Different perspectives on translational genomics in personalized medicine","authors":"Berkcan Doğan,&nbsp;Hale Göksever Çelik,&nbsp;Reyhan Diz Küçükkaya,&nbsp;Ece Gümüşoğlu Acar,&nbsp;Tuba Günel","doi":"10.4274/jtgga.galenos.2022.2021-11-4","DOIUrl":"https://doi.org/10.4274/jtgga.galenos.2022.2021-11-4","url":null,"abstract":"<p><p>Personalized medicine is a relatively new and interesting concept in the medical and healthcare industries. New approaches in current research have supported the search for biomarkers, based on the genomic, epigenomic and proteomic profile of individuals, using new technological tools. This perspective involves the potential to determine optimal medical interventions and provide the optimal benefit-risk balance for treatment, whilst it also takes a patient's personal situation into consideration. Translational genomics, a subfield of personalized medicine, is changing medical practice, by facilitating clinical or non-clinical screening tests, informing diagnoses and therapeutics, and routinely offering personalized health-risk assessments and personalized treatments. Further research into translational genomics will play a critical role in creating a new approach to cancer, pharmacogenomics, and women's health. Our current knowledge may be used to develop new solutions that can be used to minimize, improve, manage, and delay the symptoms of diseases in real-time and maintain a healthy lifestyle. In this review, we define and discuss the current status of translational genomics in some special areas including integration into research and health care.</p>","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/59/b9/JTGGA-23-314.PMC9743355.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10403331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Critical analysis of the FIGO 2018 cervical cancer staging","authors":"Leila Cristina Soares,&nbsp;José Carlos Damian Junior,&nbsp;Ricardo José de Souza,&nbsp;Marco Aurélio Pinho de Oliveira","doi":"10.4274/jtgga.galenos.2022.2022-1-10","DOIUrl":"https://doi.org/10.4274/jtgga.galenos.2022.2022-1-10","url":null,"abstract":"Cancer staging is a process that changes with technological development leading to improvements in diagnosis, prognosis, and treatment. Therefore, the International Federation of Gynecology and Obstetrics (FIGO) updated the classification of cervical cancer staging in 2018. The main changes in the FIGO 2018 system occurred in stages IA, IB, and IIIC, as well as the inclusion of any imaging modality or pathological findings to allocate the stage (1). However, some conditions still need adjustments to differentiate each stage of the system. Only the depth of invasion is now considered as the cut-off for stage IA, assigning stage IA as stroma invasion less than 5.0 mm, and further subdivided into stage IA1 and IA2 at a cutoff of 3.0 mm (1). The change at this stage was about the lateral extent of the lesion, which is no longer considered. After removing the lateral extent criterion, there is a concern with different cases being analyzed in the same way. It is also unclear whether clinically visible cases with stromal infiltration up to 3 mm would be IA1 or IB stage. Tumor size has been recognized as a prognostic factor in stage IB for a long time, with larger tumor sizes displaying higher rates of nodal involvement, and decreased survival rates (2). At this stage, FIGO 2018 has included three substages, rather than two. In terms of stage IIIB, Katanyoo (3) demonstrated that patients with a lower third vaginal invasion associated with parametrial involvement have poorer survival outcomes than patients at the same stage without a lower third of vaginal invasion. More studies are needed to verify these findings. However, if the finding of vaginal invasion in IIIB has worse prognosis, our suggestion is that stage IIIB should be subdivided into stage IIIB1, with involvement of only the parametrium, and IIIB2, with involvement of the lower third of the vagina and parametrium. In FIGO 2018, any patient with positive lymph nodes automatically gets upstaged to stage IIIC (1). Ayhan et al. (2) suggested an increase in the number of sub-stages. This classification might be more prognostic than the current 2018 FIGO staging system, as more patients would be allocated to each sub-stage (2). We suggest that lymph node involvement accompany each stage without modifying the original stage instead of grouping them in stage IIIC. Radiotherapy may be of limited value for patients with cervical adenocarcinoma and may not represent the best treatment, being an important prognostic factor for local failure (4). Different prognoses and treatment needs within the same stage would require some differentiation, as in endometrial cancer, where the serous papillary type is considered highgrade endometrial carcinoma (FIGO grade 3) (5). An optimal staging system should assign cases to prognostic categories, define the anatomical extent of disease, refer patients for individualized treatments, and compare patients and their outcomes between centers (1,2). These observations on st","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2e/00/JTGGA-23-325.PMC9743344.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10399654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The etiology of adnexal masses in women with a history of non-gynaecological malignancy: recurrence, second, primary or none?","authors":"Harika Yumru Celiksoy,&nbsp;Hamdullah Sozen,&nbsp;Merve Baktiroglu,&nbsp;Samet Topuz,&nbsp;Yavuz Salihoglu","doi":"10.4274/jtgga.galenos.2021.2021-0031","DOIUrl":"https://doi.org/10.4274/jtgga.galenos.2021.2021-0031","url":null,"abstract":"<p><strong>Objective: </strong>The occurrence of adnexal masses in patients with a history of non-gynaecological malignancy (NGM) raises concerns for malignancy, either primary or metastasis. Subsequent treatment and prognosis depends on the etiology. Our aim was to investigate the characteristics and results of the patients with suspicious adnexal masses, who had a history of NGM.</p><p><strong>Material and methods: </strong>The records of 61 patients with a history of NGM were analyzed, who were operated for an adnexal mass. Complex adnexal masses were included in the analysis while simple cysts were excluded.</p><p><strong>Results: </strong>The most common NGM origins were gastrointestinal (gastric and colorectal) tract and breast. Of all adnexal masses, four were benign (6.5%), 22 were primary ovarian malignancy (36.1%) and 35 were metastasis (57.4%). Two of the 22 primary cases were borderline ovarian tumor. Among the characteristics of primary and metastatic groups, laterality in pathology results and serum CA125 levels were statistically different (p<0.05). Among the patients with history of gastrointestinal cancers, the percentage of ovarian metastasis was 81%. Primary ovarian malignancy was most frequently (64%) observed among the patients with history of breast cancers.</p><p><strong>Conclusion: </strong>For patients with a history of gastrointestinal cancer, recurrence of the cancer in the form of ovarian metastasis was more likely, rather than a second primary cancer. The risk of primary ovarian cancer (POC) was remarkable in those with history of a breast cancer. A multidisciplinary strategy, including a gynaecological oncologist, plays an important role in managing these cases, regardless of whether or not it is a POC.</p>","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/36/da/JTGGA-23-263.PMC9743350.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10392148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The accuracy of antenatal ultrasound screening in Malta: a population-based study","authors":"Jeremy Borg Myatt,&nbsp;Miriam Gatt,&nbsp;Mark Cordina,&nbsp;Victor Grech,&nbsp;Simon Attard-Montalto","doi":"10.4274/jtgga.galenos.2022.2022-4-1","DOIUrl":"https://doi.org/10.4274/jtgga.galenos.2022.2022-4-1","url":null,"abstract":"<p><strong>Objective: </strong>To analyse the accuracy of antenatal ultrasound screening in Malta, comparing detection rates within the private and public sectors, and with the rest of Europe. To assess local trends in accuracy for each organ system.</p><p><strong>Material and methods: </strong>Ethics approval was obtained to gather routinely collected data from the national congenital anomalies registry between 2016 and 2018. This was analysed to determine local antenatal ultrasound accuracy rates and trends. Electronic medical appointment record data was also used to indirectly determine whether a significant difference existed in the detection of antenatal anomalies in mothers scanned privately and those scanned within the public sector. χ2-for-trend was used to analyse changes in the accuracy rates. European Surveillance of Congenital Anomalies (EUROCAT) data was used to compare scanning accuracy in Malta and other EUROCAT centres.</p><p><strong>Results: </strong>The local rate of undetected congenital anomalies was 62.0% for public scans and 83.9% for private scans. Local trends over the three-year period showed an improvement in accuracy rates in detecting isolated syndromes (p=0.05), anomalies of the renal system (p=0.02) and craniofacial anomalies (p=0.05). Malta’s overall performance was similar to other EUROCAT centres.</p><p><strong>Conclusion: </strong>Scans carried out within the public sector are more accurate than private scans, and Malta’s overall performance was similar to other EUROCAT centres.</p>","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/08/33/JTGGA-23-222.PMC9743353.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10457063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fetal pulmonary artery Doppler parameters in pregnancies complicated with intrahepatic cholestasis of pregnancy: a prospective case-control study","authors":"Betül Yakıştıran,&nbsp;Atakan Tanaçan,&nbsp;Orhan Altınboğa,&nbsp;Sarkhan Elbayiyev,&nbsp;Fuat Emre Canpolat,&nbsp;Aykan Yücel","doi":"10.4274/jtgga.galenos.2021.2021-9-21","DOIUrl":"https://doi.org/10.4274/jtgga.galenos.2021.2021-9-21","url":null,"abstract":"<p><strong>Objective: </strong>The primary aim of this study was to determine whether pulmonary artery acceleration time (AT) to ejection time (ET) ratio (PATET) was altered in fetuses of mothers with intrahepatic cholestasis of pregnancy (IHCP). The secondary aim was to investigate the association between fetal pulmonary artery Doppler parameters with neonatal outcomes in pregnancies complicated by IHCP.</p><p><strong>Material and methods: </strong>This prospective case control study was conducted in a tertiary perinatal-neonatal center. A total of 18 fetuses whose mothers’ pregnancies were complicated by IHCP were included as the study group and a total of 37 fetuses of mothers with healthy pregnancies were selected as controls. Fetal pulmonary artery Doppler parameters (AT; ET; AT/ET ratio) were assessed and neonatal outcomes were evaluated.</p><p><strong>Results: </strong>Mean pulmonary artery AT, ET and PATET were significantly different between the groups (p=0.001, p=0.024 and p=0.003, respectively). The mean PATET value in the IHCP group was 0.217±0.029 while in the control group it was 0.180±0.020. While PATET values were correlated with gestational age at birth, respiratory distress and need for neonatal intensive care admission were not correlated with PATET.</p><p><strong>Conclusion: </strong>Higher values of PATET may be a useful biomarker of fetal lung damage, secondary to IHCP.</p>","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6e/bd/JTGGA-23-249.PMC9743351.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10398120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical treatment of endometrioid endometrial carcinoma - laparotomy versus laparoscopy","authors":"Sascha Baum,&nbsp;Ibrahim Alkatout,&nbsp;Louisa Proppe,&nbsp;Christos Kotanidis,&nbsp;Achim Rody,&nbsp;Antonio Simone Laganà,&nbsp;Soteris Sommer,&nbsp;George Gitas","doi":"10.4274/jtgga.galenos.2022.2021-12-2","DOIUrl":"https://doi.org/10.4274/jtgga.galenos.2022.2021-12-2","url":null,"abstract":"<p><strong>Objective: </strong>Recent publications have raised doubts about the oncological safety of a laparoscopic approach in the treatment of endometrial cancer. The aim of this study was to investigate the beneficial aspects of laparoscopy versus laparotomy in patients with endometrial cancer, and present oncological outcomes.</p><p><strong>Material and methods: </strong>A retrospective study of patients who underwent surgery for the treatment of endometrioid endometrial cancer was performed. Surgical outcomes and complications in patients who were treated by laparoscopy or open surgery were compared. The patients were followed for 5-years. Patients’ characteristics, tumor stage, complications rate and oncologic outcome were analyzed.</p><p><strong>Results: </strong>A total of 151 patients were included. The laparoscopy (n=80) and laparotomy (n=71) groups were homogeneous in regards of demographic data and tumor stage. Median average blood loss (1.31 vs. 1.92 g/dL), the mean duration of hospitalization (5.73 vs. 12.25 days), intraoperative (0 vs. 6%), and severe postoperative complications (5.1 vs. 14.3%) were significantly lower in the laparoscopy group. The numbers of pelvic or para-aortic lymph nodes removed during systematic lymphadenectomy were similar in both groups. Women who underwent laparoscopy and those who underwent laparotomy had similar five-year recurrence-free survival rates (88.7% vs. 91.5%, p=0.864), as well as similar overall five-year survival rates (91.2% vs. 97.2%, p=0.094).</p><p><strong>Conclusion: </strong>The oncological outcome of laparoscopy was similar to that of laparotomy in the treatment of patients with endometrial cancer. However, surgical outcomes and morbidity rates were significantly better in patients treated by laparoscopy. Clinical trials are essential to evaluate the oncological efficacy of laparoscopy in patients with endometrial cancer.</p>","PeriodicalId":17440,"journal":{"name":"Journal of the Turkish German Gynecological Association","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2e/eb/JTGGA-23-233.PMC9743356.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10457064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}