Journal of the Formosan Medical Association最新文献

{"title":"Comment on \"Intermittent phototherapy in neonatal hyperbilirubinemia: A pilot randomized controlled trial in Taiwan\": Comparability requires a non-inferiority framework.","authors":"Zulinigeer Abudunasier, Haikuo Wang, Ming Lei","doi":"10.1016/j.jfma.2026.09.014","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.09.014","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148977204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expanding treatment guidelines for chronic hepatitis B: A narrative review.","authors":"Chih-Lin Lin, Jia-Horng Kao","doi":"10.1016/j.jfma.2026.09.015","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.09.015","url":null,"abstract":"<p><p>A significant proportion of chronic hepatitis B (CHB) patients who do not meet the conventional treatment criteria are designated \"grey zone\" or \"indeterminate phase\" patients. Although the grey zone patients have a higher HCC risk than inactive hepatitis B virus (HBV) carriers, the clinical significance of treating these patients remains controversial. Current international guidelines recommend antiviral therapy for chronic HBV infection, because antiviral therapy can reduce hepatocellular carcinoma (HCC) incidence in patients with sustained response. Several recent cohort studies showed that antiviral therapy for CHB patients in the \"grey zone\" could lower the risk of cirrhosis, HCC, and liver-related events, especially in high-risk subgroups such as older patients, those with low platelets, and HBeAg-positive individuals. Lines of evidence from retrospective studies, meta-analysis, and randomized trials also support initiating treatment before biochemical or histological deterioration occurs. However, expanding treatment indications for CHB may increase pill burden, reduce adherence, and raise the concerns of relapse or resistance. In addition, affordability and patient compliance should also be addressed. Taken together, clinical evidence and public health rationale lend support to expand treatment eligibility for a broader population of CHB patients, which is an essential step to achieve the WHO's 2030 elimination targets of HBV.</p>","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148977228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Comment on \"Long-term effect of AST-120 on delaying renal replacement therapy initiation in CKD: A propensity score overlap-weighted retrospective cohort study\".","authors":"Chin-Te Tseng, Fan-Yu Chen, Ann Charis Tan, Chih-Ching Lin","doi":"10.1016/j.jfma.2026.09.020","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.09.020","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148977169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to the comment on 'Invasive fungal rhinosinusitis: experience from a 4-year case series of 49 adult patients at a tertiary hospital in Vietnam'.","authors":"Le Buu Chau, Nguyen Nhat Tai, Nguyen Viet Khai, Dang Van Tri","doi":"10.1016/j.jfma.2026.09.017","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.09.017","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148969579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolic score for insulin resistance is associated with myopia in adolescents: A cross-sectional study with a complementary independent cohort.","authors":"Yicheng Huang, Ruixiang Fang, Xu Lian, Xiarong Huang, Zhenxin Lei, Zongzheng Lan, Nuo Xu, Yi Cui","doi":"10.1016/j.jfma.2026.09.013","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.09.013","url":null,"abstract":"<p><strong>Background: </strong>Adolescent myopia has risen sharply, yet the role of metabolic dysregulation remains unclear. This cross-sectional study investigated the association between the Metabolic Score for Insulin Resistance (METS-IR) and myopia in adolescents, and tested whether the interaction with obesity reflects biological synergy.</p><p><strong>Methods: </strong>Cross-sectional analysis of 3946 adolescents aged 12-19 years from NHANES with complementary analysis in an independent clinical cohort of 561 East Chinese adolescents. Myopia was defined as spherical equivalent ≤ -0.5 diopters. Multivariable logistic regression, subgroup analyses, restricted cubic spline analyses, and sensitivity analyses were performed to assess the association, identify effect modifiers, characterize dose-response relationships, and evaluate the interaction.</p><p><strong>Results: </strong>In NHANES, myopic adolescents had significantly higher METS-IR levels than non-myopes (32.1 vs. 31.3, P = 0.024). After full adjustment, high METS-IR (>31.84) was associated with 17% greater odds of myopia (OR = 1.17, 95% CI: 1.03-1.34), with a linear dose-response relationship and a myopia-specific exploratory reference point of 31.67. The association was significantly stronger in adolescents with obesity (P for interaction = 0.039). Sensitivity analyses using individual METS-IR components and the BMI-independent triglyceride-glucose index confirmed that the amplification of risk by obesity represents a statistical interaction consistent with biological synergy. In the independent cohort, the association remained significant after adjusting for parental myopia (OR = 1.13, 95% CI: 1.02-1.26).</p><p><strong>Conclusion: </strong>Higher METS-IR is independently associated with increased myopia risk in adolescents, particularly in those with obesity, and highlights METS-IR as a practical metabolic marker for risk stratification that may help guide nutritional and lifestyle interventions.</p>","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148956231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Clinical predictors of severe and fatal respiratory syncytial virus infection in adults and the elderly: A retrospective cohort study\".","authors":"Feng Lu, Lulu Wang","doi":"10.1016/j.jfma.2026.09.008","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.09.008","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148956175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From correlation to causation: The need for multimodal imaging and progressive overload reporting in exercise-dopamine research.","authors":"Fujun Xiao","doi":"10.1016/j.jfma.2026.09.009","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.09.009","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148956172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From promising signatures to clinically credible prediction: Strengthening microbiome-metabolome prognostic research.","authors":"Fang Yang, Jinying Cheng","doi":"10.1016/j.jfma.2026.09.007","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.09.007","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148929848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to \"From promising signatures to clinically credible prediction: Strengthening microbiome-metabolome prognostic research\".","authors":"Shuaibu Abdullahi Hudu, Emad A Morad, Ghusun M Alhazimi, Abdulgafar Olayiwola Jimoh","doi":"10.1016/j.jfma.2026.09.012","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.09.012","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148920306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Taiwan joint consensus on the management of osteoporosis in patients with diabetes.","authors":"Jawl-Shan Hwang, Jung-Fu Chen, Shih-Te Tu, Chih-Hsing Wu, Chih-Yuan Wang, Der-Sheng Han, Chun-Chuan Lee, Chung-Mei Ouyang, Shu-Mei Chen, Chung-Hwan Chen, Feng-Hsuan Liu, Horng-Yih Ou","doi":"10.1016/j.jfma.2026.08.051","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.08.051","url":null,"abstract":"<p><p>Diabetes mellitus is increasingly recognized as a major contributor to skeletal fragility. Diabetes-related factors, including alterations in bone microarchitecture and heightened fall risk, contribute to an increased risk of fragility fractures regardless of bone mineral density. To address the distinct challenges in managing bone health in diabetes, the Taiwanese Association of Diabetes Educators, in collaboration with the Taiwanese Osteoporosis Association and the Endocrine Society of the Republic of China, established an expert committee to develop consensus statements based on major existing guidelines, current evidence, and expert opinion. Early screening for osteoporosis should be considered for individuals with diabetes, and adjustments to risk calculation may be needed to avoid underestimation of fracture risk. Nonpharmacologic management is a key component of optimizing bone health. Current evidence supports that anti-osteoporosis treatments demonstrate similar efficacy in individuals with and without diabetes, although certain agents may improve glycemic parameters. Selection of antihyperglycemic therapy requires consideration of potential positive or negative impact on bone mineral density and fracture risk. System-level strategies are needed to enhance multidisciplinary collaboration, heighten awareness, support systematic management, and integrate bone health into routine care. This consensus aims to provide a practical, evidence-based approach to optimize bone health in this high-risk population.</p>","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148920325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}