Journal of the Formosan Medical Association最新文献_第7页

Response to "comment on associations between neonatal jaundice and autism spectrum disorder or attention deficit hyperactivity disorder: Nationwide population based cohort study". 对 "关于新生儿黄疸与自闭症谱系障碍或注意缺陷多动障碍之间关系的评论：基于全国人口的队列研究"。

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-09-27 DOI: 10.1016/j.jfma.2024.09.034

Hung-Chieh Chou, Hung-Chih Lin, Kuang-Hua Huang, Yu-Chia Chang

引用次数: 0

Checklist 核对表

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-09-27 DOI: 10.1016/S0929-6646(24)00423-6

引用次数: 0

Copyright transfer statement 版权转让声明

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-09-27 DOI: 10.1016/S0929-6646(24)00425-X

引用次数: 0

Genophenotypic correlates and long-term outcome prognosticators of left ventricular non-compaction in children. 儿童左心室不充盈的基因型相关性和长期预后结果。

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-09-26 DOI: 10.1016/j.jfma.2024.09.032

Wei-Chieh Tseng, Shuenn-Nan Chiu, Jyh-Ming Jimmy Juang, Wen-Pin Chen, Ni-Chung Lee, Mei-Hwan Wu

{"title":"Genophenotypic correlates and long-term outcome prognosticators of left ventricular non-compaction in children.","authors":"Wei-Chieh Tseng, Shuenn-Nan Chiu, Jyh-Ming Jimmy Juang, Wen-Pin Chen, Ni-Chung Lee, Mei-Hwan Wu","doi":"10.1016/j.jfma.2024.09.032","DOIUrl":"https://doi.org/10.1016/j.jfma.2024.09.032","url":null,"abstract":"Background: To investigate the outcomes, clinical prognosticators, and genetic profiles of pediatric left ventricular non-compaction (LVNC).Methods: All subjects were <18 years old, diagnosed with LVNC between January 2008 and December 2020. Whole-exome sequencing was undertaken. The primary endpoint was composite outcome, including death, heart transplant, and left ventricular assist device implantation.Results: Thirty-three patients were enrolled, males predominating (57.6%). Median age at diagnosis was 0.33 (0.1-7.2) years. Family history was documented in four (12.1%). Five (15.2%) had sustained arrhythmias. Mean follow-up period was 9.5 years, and 5- and 10-year event-free survival were 84.8% and 66.9%, respectively. Seven died of heart failure, four received heart transplants, and one required left ventricular assist device placement. Log of baseline NT-proBNP (adjusted odds ratio [aOR] = 4.4, p = 0.012) and lack of improvement in NT-proBNP (aOR = 41.2, p = 0.033) impacted the primary outcome most significantly. Eighteen out of 25 genetic testing (72%) revealed chromosomal anomalies, or pathogenic or likely pathogenic variants. Three genetic variants (PLEKHM2 p.G419R, RYR2 p.V2571A, and SCN5A p.M1676I) were significantly associated with the primary outcome (p = 1.52 × 10-6).Conclusions: Pediatric LVNC is a rare disorder with variable genetic underpinnings. Baseline NT-proBNP values and lack of improvement in NT-proBNP levels were important predictors of poor long-term outcomes. Pathogenic genetic variants or chromosomal anomalies are not unusual.","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Practices for introducing complementary foods in Taiwan: A nationwide survey from 2013 to 2016. 台湾引进辅食的做法：2013年至2016年全国调查。

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-09-25 DOI: 10.1016/j.jfma.2024.09.026

Jia-Jia Tsai, Yi-Yu Su, Hsi Chang, Hsiu-Chen Lin, Jung-Tzu Ku, Mu-Ming Chien

{"title":"Practices for introducing complementary foods in Taiwan: A nationwide survey from 2013 to 2016.","authors":"Jia-Jia Tsai, Yi-Yu Su, Hsi Chang, Hsiu-Chen Lin, Jung-Tzu Ku, Mu-Ming Chien","doi":"10.1016/j.jfma.2024.09.026","DOIUrl":"https://doi.org/10.1016/j.jfma.2024.09.026","url":null,"abstract":"Background/purpose: Introducing complementary foods to infants is a critical stage in their healthy growth and development process. In this study, we analyzed the feeding habits and choices of caregivers in Taiwan during this essential transition period.Methods: Data from the 2013-2016 Nutrition and Health Survey in Taiwan were analyzed. Using a multistage stratified sampling technique, we collected data through questionnaires on the feeding practices, challenges, and information sources associated with complementary feeding. We also investigated the timing of introducing various foods. Certain feeding indicators recommended by the World Health Organization were modified and used for analysis.Results: Among 439 caregivers of infants aged 2-24 months, complementary feeding typically began at 5 months, and it primarily began with cereals and pureed foods. At 6-8 months of age, 98.29% of the infants received these foods. Only 48.39% of infants aged 6-24 months consumed eggs or flesh foods. Among the primary challenges for caregivers were concerns regarding infants' adaptation to new foods (38.2%), refusal of foods by infants (37.1%), and uncertainty regarding which foods to introduce (11.4%). The main sources of information were friends and family (46.9%), the Internet (46.5%), and baby care books (35.6%). Notably, approximately 51% of the respondents used commercial baby foods.Conclusion: In Taiwan, although the majority of infants begin complementary feeding on time, the introduction of eggs and flesh foods is typically delayed. Given the growing reliance on the Internet in the modern age, accurate feeding information should be disseminated online.","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Febrile young infants and the association with enterovirus infection. 发热幼儿与肠道病毒感染的关系。

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-09-24 DOI: 10.1016/j.jfma.2024.09.025

Ya-Li Hu, Ai-Ling Cheng, Shun-Hua Chen, Chi-Tai Fang, Luan-Yin Chang

{"title":"Febrile young infants and the association with enterovirus infection.","authors":"Ya-Li Hu, Ai-Ling Cheng, Shun-Hua Chen, Chi-Tai Fang, Luan-Yin Chang","doi":"10.1016/j.jfma.2024.09.025","DOIUrl":"https://doi.org/10.1016/j.jfma.2024.09.025","url":null,"abstract":"Background: Enterovirus is a common pediatric infectious disease, but the epidemiological data in young infants were lacking. This study aims to evaluate the role of enterovirus in febrile young infants and identify risk factors for severe infections.Methods: We enrolled febrile infants younger than 90 days admitted to National Taiwan University Hospital from January 2010 to June 2021. Enterovirus infection was confirmed via viral isolation or pan-enterovirus PCR. Central nervous system involvement was defined by positive culture or PCR in cerebrospinal fluid. Severe complications included sepsis, hepatic failure, myocarditis, shock, encephalitis, acute kidney injury, respiratory failure, and multiorgan failure.Results: Out of 840 febrile infants, 17.4% (n = 146) had enterovirus infection. Among these, 46% (n = 67) presented with meningitis and/or encephalitis. Early-onset enterovirus infection within the first two weeks of life was significantly linked to increased risks of anemia (hemoglobin <9 g/dL), ICU admission, central nervous system involvement, shock, hepatic failure, and mortality. Multivariable logistic regression identified high-risk serotypes (aOR 17.4, [95% CI 1.58, 191.5], p = 0.019) and hemoglobin <9 g/dL (aOR 44.9, [95% CI 5.6, 357.6], p < 0.001) as significant risk factors for severe complications.Conclusions: Enterovirus accounted for 17.4% of the etiology in febrile young infants and the case-fatality rate was 2%. Febrile young infants who had risk factors of enterovirus infection should consider viral culture or PCR examination for confirmation.","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on "Severity of tongue base collapse in various body positions in patients with obstructive sleep apnea: A trajectory analysis". 关于 "阻塞性睡眠呼吸暂停患者不同体位下舌根塌陷的严重程度：轨迹分析

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-09-24 DOI: 10.1016/j.jfma.2024.09.027

Chunmei Huang, Dongsheng Gu

引用次数: 0

Blood pressure targets, medication consideration and special concerns in elderly hypertension part I: General principles and special considerations. 老年高血压的血压目标、用药注意事项和特别关注事项第一部分：一般原则和特别注意事项。

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-09-24 DOI: 10.1016/j.jfma.2024.09.023

Heng-Yu Pan, Po-Lung Yang, Chun-Hsien Lin, Chun-Yi Chi, Chia-Wen Lu, Tai-Shuan Lai, Chih-Fan Yeh, Michael Yu-Chih Chen, Tzung-Dau Wang, Hsien-Li Kao, Yen-Hung Lin, Mu-Cyun Wang, Chih-Cheng Wu

{"title":"Blood pressure targets, medication consideration and special concerns in elderly hypertension part I: General principles and special considerations.","authors":"Heng-Yu Pan, Po-Lung Yang, Chun-Hsien Lin, Chun-Yi Chi, Chia-Wen Lu, Tai-Shuan Lai, Chih-Fan Yeh, Michael Yu-Chih Chen, Tzung-Dau Wang, Hsien-Li Kao, Yen-Hung Lin, Mu-Cyun Wang, Chih-Cheng Wu","doi":"10.1016/j.jfma.2024.09.023","DOIUrl":"https://doi.org/10.1016/j.jfma.2024.09.023","url":null,"abstract":"To achieve a consensus on optimal blood pressure (BP) targets for older adults remains challenging, necessitating a trade-off between cardiovascular benefits and the risk of impaired organ perfusion. Evidence suggests that age and frailty have a minimal influence on the cardiovascular benefits of intensive BP control in community-dwelling elderly. Nonetheless, an increased incidence of acute kidney injury with intensive BP control has been observed in octogenarians. Therefore, it is recommended to maintain systolic BP below 130 mmHg for hypertensive patients aged 65-80 years. If well-tolerated, a systolic BP target below 120 mmHg can be recommended for patients with chronic kidney disease (CKD). However, no conclusive evidence supports a stringent BP target for patients aged 80 years and older. The selection of antihypertensive medications for elderly patients requires consideration of their cardiovascular condition and potential contraindications. Combination therapy may be necessary to achieve the desired BP target. Angiotensin-converting enzyme inhibitors or angiotensin receptor blockers are the primary choices for patients with CKD. Newer generation mineralocorticoid receptor antagonists may further reduce the risk of cardiovascular or renal events in this population. In conclusion, managing hypertension in elderly patients requires a personalized approach that balances cardiovascular benefits with potential risks, considering individual health profiles and tolerability.","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to letter "Enhancing the Validity of EVT outcome analysis through Comprehensive Statistical Methods". 对 "通过综合统计方法提高 EVT 结果分析的有效性 "一信的回复。

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-09-23 DOI: 10.1016/j.jfma.2024.09.021

Yu-Ming Chang, Sheng-Hsiang Lin, Pi-Shan Sung

引用次数: 0

Comment on "Late creation of vascular access increased post-hemodialysis mortality, hospitalization, and health-care expenditure: A population-based cohort study in Taiwan". 关于 "延迟建立血管通路会增加血液透析后的死亡率、住院率和医疗支出：台湾一项基于人口的队列研究"。

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-09-21 DOI: 10.1016/j.jfma.2024.09.017

Zhixin Zhang

引用次数: 0