Journal of the Formosan Medical Association最新文献_第6页

Blood pressure targets, medication consideration and unique concerns in elderly hypertension IV: Focus on frailty, orthostatic hypotension, and resistant hypertension. 老年高血压的血压目标、用药考虑和独特关注点 IV：关注虚弱、正性低血压和抵抗性高血压。

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-10-05 DOI: 10.1016/j.jfma.2024.09.022

Po-Sheng Wu, Chia-Ter Chao, Chien-Hao Hsiao, Chiu-Fen Yang, Ying-Hsiang Lee, Hung-Ju Lin, Chih-Fan Yeh, Long-Teng Lee, Kuo-Chin Huang, Meng-Chih Lee, Cheng-Kuo Huang, Yen-Hung Lin, Michael Yu-Chih Chen, Ding-Cheng Chan

{"title":"Blood pressure targets, medication consideration and unique concerns in elderly hypertension IV: Focus on frailty, orthostatic hypotension, and resistant hypertension.","authors":"Po-Sheng Wu, Chia-Ter Chao, Chien-Hao Hsiao, Chiu-Fen Yang, Ying-Hsiang Lee, Hung-Ju Lin, Chih-Fan Yeh, Long-Teng Lee, Kuo-Chin Huang, Meng-Chih Lee, Cheng-Kuo Huang, Yen-Hung Lin, Michael Yu-Chih Chen, Ding-Cheng Chan","doi":"10.1016/j.jfma.2024.09.022","DOIUrl":"https://doi.org/10.1016/j.jfma.2024.09.022","url":null,"abstract":"Hypertension increases the risk of cardiovascular disease in the elderly. Although treating hypertension can reduce the risk of cardiovascular disease and its related mortality, it is also challenging because these patients could have frailty, orthostatic hypotension (OH) and resistant hypertension (RHTN), which makes them more susceptible to treatment-related adverse events. Identifying such patients and tailoring the choice of drugs and blood pressure targets is crucial to balance the harms and benefits. The Clinical Frailty Scale is recommended to assess elderly patients with hypertension and frailty. For very frail patients, unnecessary medications should be deprescribed to avoid adverse events. Hypertension and OH frequently co-occur in the elderly, and recognizing and managing OH is essential to prevent falls and adverse events. The management of blood pressure in elderly patients with frailty, OH, and RHTN is complex, requiring the patients, their family and caregivers to be involved in decision-making to ensure that treatment plans are well-informed and aligned with the patient's needs.","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ranolazine effects on exercise tolerance and angina frequency in Taiwanese stable angina: A bridging study of the CARISA randomized trial. 雷诺拉嗪对台湾稳定型心绞痛患者运动耐量和心绞痛频率的影响：CARISA 随机试验的桥接研究。

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-10-05 DOI: 10.1016/j.jfma.2024.09.018

Jen-Kuang Lee, I-Chang Hsieh, Po-Hsun Huang, Yen-Wen Wu, Jung-Chung Hsu, Jen-Yuan Kuo, Po-Yuan Chang, Cheng-Hsueh Wu, Juey-Jen Hwang

{"title":"Ranolazine effects on exercise tolerance and angina frequency in Taiwanese stable angina: A bridging study of the CARISA randomized trial.","authors":"Jen-Kuang Lee, I-Chang Hsieh, Po-Hsun Huang, Yen-Wen Wu, Jung-Chung Hsu, Jen-Yuan Kuo, Po-Yuan Chang, Cheng-Hsueh Wu, Juey-Jen Hwang","doi":"10.1016/j.jfma.2024.09.018","DOIUrl":"https://doi.org/10.1016/j.jfma.2024.09.018","url":null,"abstract":"Background: The effectiveness of Ranolazine on chronic angina had been proved and launched in the United States. This study aimed to determine whether add-on Ranolazine could also be effective in Taiwanese population with persisting angina symptoms despite taking conventional antianginal agents.Methods: This is a multi-center, randomized, parallel, double-blind comparative study. The endpoint is to compare the change from the baseline of the exercise treadmill test (ETT) performing duration between add-on ranolazine and placebo at week 12.Results: 46 patients were evaluable for the efficacy and safety endpoints. The mean change from baseline in ETT duration at week 12 was increased in the treatment and control group, and their mean difference was 20.8 s. All data in the Taiwanese population was like those in the CARISA study (24.0 s). The safety evaluation revealed that patients were tolerable to the add-on ranolazine therapy. The AE incidence for both ranolazine and placebo was 34.8%. The data were comparable to the past studies despite the limited statistical power.Conclusion: The add-on ranolazine therapy shows the potential to raise the exercise performance and tolerance of patients with chronic angina.","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reply to Dr. Wiwanitkit's comments on large language model applications in emergency medicine and critical care. 回复 Wiwanitkit 博士关于急诊医学和重症监护中大型语言模型应用的评论。

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-10-04 DOI: 10.1016/j.jfma.2024.09.036

Haw Hwai, Yi-Ju Ho, Chih-Hung Wang, Chien-Hua Huang

引用次数: 0

Clinicopathological characteristics of unicentric Castleman disease: A single-center experience of 12 patients. 单中心卡斯特曼病的临床病理特征：12名患者的单中心经验

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-10-02 DOI: 10.1016/j.jfma.2024.09.038

Yi-Chieh Lee, Chao-Wen Lu, Min-Shu Hsieh, Hsao-Hsun Hsu

{"title":"Clinicopathological characteristics of unicentric Castleman disease: A single-center experience of 12 patients.","authors":"Yi-Chieh Lee, Chao-Wen Lu, Min-Shu Hsieh, Hsao-Hsun Hsu","doi":"10.1016/j.jfma.2024.09.038","DOIUrl":"https://doi.org/10.1016/j.jfma.2024.09.038","url":null,"abstract":"Background: Castleman disease (CD) is an uncommon lymphoproliferative disorder with distinct pathological characteristics. Unicentric Castleman disease (UCD) presents as a single lymph node enlargement, often without significant symptoms. Complete surgical resection is the standard treatment for UCD. This study aimed to explore the clinicopathological features of UCD in a Taiwanese population.Methods: We retrospectively identified 12 patients with UCD who had undergone surgical treatment between January 1, 2006 and June 30, 2022 at the National Taiwan University Hospital. Clinical and radiological findings were retrieved from medical records. All available pathological slides were reviewed.Results: The patients' mean age was 38.1 years (range, 17 to 69); five (41.7%) were male, and seven (58.3%) were female. Nearly all cases of UCD were in the mediastinum, except for one case in the neck. Most patients were asymptomatic and without abnormal laboratory test results. Computed tomography revealed well-defined tumor borders, contrast enhancement, and occasional calcification. Ten patients underwent en bloc tumor resection, while the remaining two underwent partial resection. Among them, seven (58.3%) underwent video-assisted thoracoscopic surgery (VATS), and four (33.3%) underwent thoracotomy. The mean follow-up duration was 92 months. The patients who underwent total resection had no recurrence.Conclusion: Detailed clinicopathological information on UCD in the Taiwanese population is present in our article. Both complete and partial surgery are effective for treatment. VATS may be preferred over thoracotomy due to less operative time and bleeding.","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142372182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insights of Fabry disease: Expert consensus approach for screening, diagnosis, and multidisciplinary management in chronic kidney disease. 法布里病的见解：慢性肾脏病筛查、诊断和多学科管理的专家共识方法。

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-10-01 DOI: 10.1016/j.jfma.2024.09.033

Cheng-Jui Lin, Feng-Jung Yang, Chih-Jen Wu, Ming-Ju Wu, Mai-Szu Wu

{"title":"Insights of Fabry disease: Expert consensus approach for screening, diagnosis, and multidisciplinary management in chronic kidney disease.","authors":"Cheng-Jui Lin, Feng-Jung Yang, Chih-Jen Wu, Ming-Ju Wu, Mai-Szu Wu","doi":"10.1016/j.jfma.2024.09.033","DOIUrl":"https://doi.org/10.1016/j.jfma.2024.09.033","url":null,"abstract":"The prevalence of Fabry disease (FD) among males with chronic kidney disease (CKD) of unknown etiology in Taiwan is 0.6%. Despite this, FD is frequently overlooked in clinical settings. To address this issue, two consensus meetings were conducted in Taiwan-one in August 2022 and another in April 2023. The first meeting established screening criteria based on age, gender, family history, cardiac involvement, and symptoms. The second meeting, with a multidisciplinary team, developed treatment recommendations. The consensus emphasizes the importance of proactive data collection in dialysis units and outpatient follow-ups to enhance FD detection and management. The screening algorithm recommends incorporating FD screening into the diagnostic process for CKD patients, regardless of age. Priority is given to patients with a family history of FD, early stroke history, or classical FD symptoms. Comprehensive screening is also advised for CKD patients without obvious classical symptoms. Screening protocols for males include measuring α-galactosidase A enzyme activity, with reduced activity leading to further tests such as lyso-Gb3 level quantification and genetic analysis. For females, the protocol involves evaluating lyso-Gb3 plasma levels and genetic testing. FD, though often underestimated, is more prevalent than recognized and necessitates a multidisciplinary approach for timely diagnosis. Enhancing awareness and adopting a comprehensive approach are essential for improving patient outcomes.","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term health outcomes of children born by cesarean section: A nationwide population-based retrospective cohort study in Taiwan. 剖腹产婴儿的长期健康状况：台湾一项基于全国人口的回顾性队列研究。

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-10-01 DOI: 10.1016/j.jfma.2024.09.024

Wei Chard Chua, Yi-Lung Chen, Cheng-Fang Yen, Hsiu-Lin Chen

{"title":"Long-term health outcomes of children born by cesarean section: A nationwide population-based retrospective cohort study in Taiwan.","authors":"Wei Chard Chua, Yi-Lung Chen, Cheng-Fang Yen, Hsiu-Lin Chen","doi":"10.1016/j.jfma.2024.09.024","DOIUrl":"https://doi.org/10.1016/j.jfma.2024.09.024","url":null,"abstract":"Background: Taiwan had high cesarean rate which exceeded the recommended threshold (15%), set by WHO. However, there have not a comprehensive study to discuss the long-term offspring consequences of cesarean section (CS). This study aimed to show whether allergy disorders, obesity and respiratory infection of children are associated with modes of delivery, using the National Health Insurance Research Database (NHIRD) of Taiwan.Methods: This study used the maternal and child health database of NHIRD. We included the children who birth between 2004 and 2013 and inter-linked the database of the mother and children. The participants were followed until 2018/12/31. We performed a Cox proportional hazards model to identify the association of CS with respiratory tract infection, allergy disorder, and obesity diagnosed in childhood.Results: CS significantly increased the risk of developed childhood asthma (adjusted hazard ratio [aHR] = 1.03; 95% confidence interval [CI]: 1.02-1.03), allergy rhinitis (aHR = 1.04; 95% CI: 1.04-1.05), atopic dermatitis (aHR = 1.05; 95% CI: 1.04-1.06), respiratory tract infection (aHR = 1.07; 95% CI: 1.06-1.07) and overweight (aHR = 1.29; 95% CI: 1.18-1.40) even after adjusting with confounding factor. Development of food allergy (aHR = 1.13; 95% CI: 0.87-1.47) was not associated with cesarean section.Conclusion: This study indicated that children delivered by CS more commonly developed respiratory tract infections, asthma, allergic rhinitis, atopic dermatitis, obesity than children delivered vaginally. Among these, obesity have a stronger association with cesarean section.","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Reply to comment on "The association between vitamin D consumption and gallstones in US adults: A cross-sectional study from the national health and nutrition examination survey". 对 "美国成年人维生素 D 摄入量与胆结石之间的关系：全国健康与营养状况调查横断面研究"。

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-09-30 DOI: 10.1016/j.jfma.2024.09.030

Chuan Zhang

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Comment on "Adjuvant chemotherapy for stage II and III gastric adenocarcinoma: A retrospective analysis with long-term follow-up". 就 "II期和III期胃腺癌的辅助化疗：长期随访的回顾性分析 "发表评论。

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-09-29 DOI: 10.1016/j.jfma.2024.09.029

Feng Ma, Shouqin Hu

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Authorship statement 作者声明

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-09-27 DOI: 10.1016/S0929-6646(24)00424-8

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Guide for Authors 作者指南

IF 2.6 3区医学

Journal of the Formosan Medical Association Pub Date : 2024-09-27 DOI: 10.1016/S0929-6646(24)00422-4

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