Journal of the Formosan Medical Association最新文献

{"title":"Comment on \"Utilization of home-based traditional Chinese medicine in a homebound population under the integrated home-based medical care program in Taiwan\".","authors":"Xue Li, Yue Tan, Baoying Zhang","doi":"10.1016/j.jfma.2025.10.006","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.10.006","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145275106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Border inspection of imported medicines and medical devices in Taiwan.","authors":"Yueh-Hao Pai, Tsung-Hsi Wu, Wei-Chih Cheng","doi":"10.1016/j.jfma.2025.10.007","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.10.007","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145275184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response letter to the comment on \"Utilization of home-based traditional Chinese medicine in a homebound population under the Integrated Home-Based Medical Care program in Taiwan\".","authors":"Wen-Chiung Chang, Yi-Chang Su","doi":"10.1016/j.jfma.2025.10.010","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.10.010","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145275189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of atropine, orthokeratology lenses, defocus contact lenses, and Defocus Incorporated Multiple Segments spectacle lenses on choroidal thickness.","authors":"Hou-Ting Kuo, Hsin Tseng, Yu-Chuen Huang, Yu-Te Huang, Hui-Ju Lin","doi":"10.1016/j.jfma.2025.10.012","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.10.012","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to compare the effects of various myopia control methods, including atropine, orthokeratology (OK) lenses, defocus soft contact lenses (MiSight®, MS), and defocus incorporated multiple segment spectacle lenses (Hyoa Miyosmart®, HY), on choroidal thickness in children with myopia.</p><p><strong>Methods: </strong>This single-center, retrospective study was conducted at China Medical University Hospital in Taichung, Taiwan, from December 2023 to September 2024. Patients were divided into four groups based on treatment modality: atropine, OK lenses, MS lenses, and HY lenses. Choroidal thickness was measured after six months of treatment using enhanced depth imaging OCT at seven specific locations. Statistical analysis was performed using one-way ANOVA and post-hoc tests, with significance set at P < 0.05.</p><p><strong>Results: </strong>A total of 51 children (102 eyes) aged 5-15 years were included in the study. Participants were divided into four groups: atropine (n = 34), OK lenses (n = 44), MS lenses (n = 16), and Defocus Incorporated Multiple Segments spectacle lens (DIMS), HY lenses (n = 8). Both OK lenses and DIMS lenses demonstrated significantly greater choroidal thickness compared to atropine across most measurement points. OK lenses consistently exhibited thicker choroids than MS lenses, while MS lenses showed no significant difference compared to atropine. HY lenses exhibited similar effects to OK lenses, indicating comparable efficacy in enhancing choroidal thickness.</p><p><strong>Conclusion: </strong>Children treated with orthokeratology and defocus-incorporated spectacle lenses exhibited greater choroidal thickness compared to those using defocus soft contact lenses and atropine, highlighting the variability in mechanisms among different myopia control interventions.</p>","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145275141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The toxicity of hybrid techniques combining hypofractionated whole breast radiotherapy with concomitant tumor bed boost in patients with breast cancer.","authors":"Yen-Ting Liu, Kuan-An Chu, Shih-Ting Huang, Chia-Wei Shen, Jia-Hung Liou, Hsiang-Kuang Tony Liang, Sung-Hsin Kuo","doi":"10.1016/j.jfma.2025.09.037","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.09.037","url":null,"abstract":"<p><strong>Background: </strong>We examined the acute toxicity of hypofractionated breast radiotherapy (HFRT) with hybrid techniques combining field-in-field intensity-modulated RT (FIF-IMRT) to the whole breast (WB) with inverse-IMRT for concomitant boost (CB) to the tumor bed.</p><p><strong>Methods: </strong>This prospective exploratory study enrolled patients with early-stage breast cancer (EBC) or breast ductal carcinoma in situ (DCIS) from January 2020 after breast-conserving surgery. All patients consistently received a 16-fraction hybrid 40 Gy FIF-IMRT plans for WB, CB 8 Gy inverse-IMRT to the tumor bed (hybrid-CB group). Identical contours and planning target volume coverage were replanned with conventional tangential FIF-IMRT for WB (50 Gy in 25 fractions), followed by electron beams to the tumor bed (10 Gy in 5 fractions) (sequential group).</p><p><strong>Results: </strong>We enrolled 25 patients with EBC and 9 with breast DCIS; 2 (5.9 %) patients had grade 2 acute radiation dermatitis, and 5 (14.7 %) patients had grade 1 skin fibrosis. No recurrence was observed during the median follow-up of 44 months. Mean homogeneity index in the hybrid-CB and sequential groups were 8.9 and 18.6, respectively (p < 0.01). Considering left-sided disease, we found no significant differences in mean, maximal dose, and V5 of heart between groups (p = 0.09, 0.80, and 0.06). V20 values of the ipsilateral lung dose were 13.0 % and 12.9 % (p = 0.47) in the hybrid-CB and sequential groups, respectively, while normal tissue complication probability parameters for breast fibrosis were 20.02 % and 22.13 %, respectively (p < 0.01).</p><p><strong>Conclusion: </strong>HFRT combined with FIF-IMRT for WB with inverse-IMRT CB to the tumor bed causes rare acute radiation dermatitis and decreases moderate-to-severe breast fibrosis without compromising disease control.</p>","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Impact of actigraphy-based circadian rest-activity rhythms on functional outcomes in post-stroke rehabilitation\".","authors":"Shyam Sundar Sah, Abhishek Kumbhalwar","doi":"10.1016/j.jfma.2025.10.003","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.10.003","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Evaluating the role of toe grip strength and anthropometric measures in diagnosing sarcopenia: A predictive model for middle-aged and older adults in Taiwan\".","authors":"Baoying Zhang, Yue Tan, Xue Li","doi":"10.1016/j.jfma.2025.09.041","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.09.041","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and clinical impact of JAK2-CHIP: Association with Parkinsonism and hematologic changes in a population cohort.","authors":"Cih-En Huang, Yi-Yang Chen, Chang-Hsien Lu, Yao-Ren Yang, Yu-Ying Wu, Chia-Hung Wu, Wen-Yung Tsai, Meng-Hung Lin, Hsing-Yi Tsou, Chian-Pei Li, Ying-Hsuan Wang, Chih-Cheng Chen","doi":"10.1016/j.jfma.2025.09.039","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.09.039","url":null,"abstract":"<p><strong>Background: </strong>JAK2V617F-associated clonal hematopoiesis of indeterminate potential (JAK2-CHIP) has been implicated in cardiovascular disease through inflammatory and thrombotic mechanisms. However, its role in microthromboembolism-related events (miTE-REs), particularly neurodegenerative disorders, remains underexplored.</p><p><strong>Methods: </strong>In this retrospective cohort study, we screened 1768 individuals from a health screening population for JAK2V617F using a high-sensitivity qCAST-Duplex PCR assay. To enhance efficiency, we employed a pooled PCR strategy: genomic DNA from 10 samples was combined per reaction. Given the assay's detection limit of 0.01 %, this approach allowed identification of any individual sample with a mutant allele burden (AB) > 0.1 %. Positive pools were deconvoluted and tested individually. Clinical data were analyzed to assess associations between JAK2-CHIP and miTE-REs, including Parkinsonism, dementia, Alzheimer's disease, heart failure, and avascular necrosis. Temporal changes in AB were evaluated in participants with serial blood samples.</p><p><strong>Results: </strong>JAK2-CHIP was identified in 32 individuals (1.8 %), with prevalence increasing with age. Carriers had a significantly higher prevalence of Parkinsonism than non-carriers (15.6 % vs. 6.3 %, p = 0.035). Carriers with AB ≥1 % had elevated platelet and basophil counts, suggesting subclinical myeloid lineage activation. Among those with serial data, 22.7 % showed clonal expansion, though none developed hematologic malignancy.</p><p><strong>Conclusion: </strong>JAK2-CHIP is associated with increased prevalence of Parkinsonism in otherwise healthy individuals, possibly via microvascular or inflammatory pathways. Elevated platelet and basophil counts among carriers support early functional consequences of this mutation. These findings highlight the clinical relevance of detecting JAK2-CHIP in general populations and underscore its potential as a biomarker for neurologic risk stratification and longitudinal monitoring.</p>","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methodological considerations on the interpretation of far-infrared therapy findings.","authors":"Wei-Hao Lee, Hung-Hsiang Liou, Chung-Kuan Wu","doi":"10.1016/j.jfma.2025.09.042","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.09.042","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145228594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to comment on \"Pregnancy and perinatal outcomes of mothers with inflammatory bowel disease in Taiwan: A national database analysis\".","authors":"Chi-Nien Chen, Hsin-Yun Wu, Meng-Tzu Weng, Chiuan-Bo Huang, Chien-Chih Tung, Shu-Chen Wei, Po-Nien Tsao","doi":"10.1016/j.jfma.2025.09.043","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.09.043","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145228546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}