{"title":"Guide for Authors","authors":"","doi":"10.1016/S0929-6646(25)00254-2","DOIUrl":"10.1016/S0929-6646(25)00254-2","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":"124 6","pages":"Pages e1-e8"},"PeriodicalIF":2.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144169697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Checklist","authors":"","doi":"10.1016/S0929-6646(25)00255-4","DOIUrl":"10.1016/S0929-6646(25)00255-4","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":"124 6","pages":"Page e9"},"PeriodicalIF":2.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144169715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Authorship statement","authors":"","doi":"10.1016/S0929-6646(25)00256-6","DOIUrl":"10.1016/S0929-6646(25)00256-6","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":"124 6","pages":"Pages e10-e11"},"PeriodicalIF":2.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144169716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Copyright transfer statement","authors":"","doi":"10.1016/S0929-6646(25)00257-8","DOIUrl":"10.1016/S0929-6646(25)00257-8","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":"124 6","pages":"Page e12"},"PeriodicalIF":2.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144169717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Sarcopenia and myosteatosis are associated with low survival in patients receiving lenvatinib for unresectable hepatocellular carcinoma\".","authors":"Lu Qu, Rou Li, Yan Li","doi":"10.1016/j.jfma.2025.05.032","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.05.032","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144174389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Alteration of gut microbial composition associated with the therapeutic efficacy of fecal microbiota transplantation in Clostridium difficile infection\".","authors":"Liao Qingsong","doi":"10.1016/j.jfma.2025.05.033","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.05.033","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144174387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DAB2 binds to LASP1 to participate in migration and invasion of non-small cell lung cancer through TGF-β/Smad pathway.","authors":"Qing Li, Saili Zeng, Hui Long, Yunwu He, Rongfang Tu, Yonglin Li, Xianfei Liu, Qiao Xiao, Xing He, Zhenhua He","doi":"10.1016/j.jfma.2025.05.019","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.05.019","url":null,"abstract":"<p><strong>Background: </strong>Disabled homolog 2 (DAB2) and LIM and Src homology 3 region (SH3) domain protein 1 (LASP1) have been shown to play a role in the course of non-small cell lung cancer (NSCLC). However, the specific regulatory mechanism remains to be elucidated. The aim of this work was to investigate the role and interaction between DAB2 and LASP1 in the development of NSCLC.</p><p><strong>Methods: </strong>The western blot assay was conducted to analyze protein levels. Immunohistochemical (IHC) staining assay was employed to evaluate the expressions of DAB2 and LASP1. The cell proliferation was examined using colony formation assay. Co-immunoprecipitation (Co-IP) assay was applied to analyze the binding relationship between DAB2 and LASP1. Cell counting kit-8 (CCK-8) assay was utilized for detection of cell viability. The invasion and migration properties of A549 cells were detected by using the transwell assay.</p><p><strong>Results: </strong>DAB2 was lowly expressed while LASP1 was highly expressed in NSCLC tissues and cells compared with non-tumor tissues and normal lung cells, and there was interaction between DAB2 and LASP1. Overexpression of DAB2 served as a tumor suppressor to suppress the proliferation, migration as well as invasion of NSCLC cells. LASP1 knockdown restrained NSCLC cell migration and invasion through suppressing TGF-β/Smad pathway. Moreover, the biological behavior induced by DAB2 overexpression were reversed after oe-LASP1 transfection, and DAB2 and LASP1 were involved in the process of NSCLC through TGF-β/Smad pathway.</p><p><strong>Conclusion: </strong>DAB2 could bind to LASP1 to participate in NSCLC development, involving the regulatory mechanism of TGF-β/Smad pathway.</p>","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144174392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endoscopic and novel approaches for evaluation of indeterminate biliary strictures.","authors":"Tung-Yen Lin, Chieh-Chang Chen, Yu-Ting Kuo, Wei-Chih Liao","doi":"10.1016/j.jfma.2025.05.036","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.05.036","url":null,"abstract":"<p><p>Indeterminate biliary strictures are defined as strictures which evade definitive diagnosis after endoscopic retrograde cholangiopancreatography (ERCP)-assisted sampling with brush cytology and/or forceps biopsy and pose significant clinical challenges. While most indeterminate biliary strictures are attributed to malignancies, up to one-third are benign strictures. False-negative and false-positive diagnoses lead to delayed or inappropriate treatment with untoward clinical consequences. Peroral cholangioscopy (POC) and single-operator cholangioscopy (SOC) have demonstrated superior diagnostic accuracy over traditional ERCP-based techniques through enhanced visualization and targeted biopsy. Endoscopic ultrasound (EUS)-guided tissue sampling also achieves superior sensitivity and diagnostic accuracy compared with ERCP-based tissue sampling. The 2025 ESGE guideline proposes an algorithm for optimizing the utilization of ERCP-based and EUS-guided tissue sampling and cholangioscopy with consideration of the stricture location. Furthermore, molecular diagnostic tools such as fluorescence in situ hybridization (FISH) and next-generation sequencing (NGS) enable the detection of chromosomal and genetic alterations commonly associated with biliary malignancies, thereby enhancing the sensitivity for malignancy. This review summarizes recent advances in the diagnostic work-up of indeterminate biliary strictures and emerging diagnostic strategies and modalities.</p>","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144159880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Author reply to letter to the editor \"Arsenic exposure and trend of incidence in urinary cancer from 1979 to 2019: A nationwide population-based study\".","authors":"Yi-Sheng Tai","doi":"10.1016/j.jfma.2025.05.035","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.05.035","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144174277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to \"comment on risk of colon polyps and colorectal cancer in primary biliary cholangitis, a population-based retrospective cohort study in taiwan\".","authors":"Pei-Tzu Chen, Hsuan-Wei Chen","doi":"10.1016/j.jfma.2025.05.030","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.05.030","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144174395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}