Journal of the Formosan Medical Association最新文献_第8页

Response to "Comment on: 'Red cell distribution width as an inflammatory biomarker for predicting one-year survival after geriatric hip fracture'". 对“红细胞分布宽度作为预测老年髋部骨折后1年生存率的炎症生物标志物”的评论”的回应。

IF 2.5 3区医学

Journal of the Formosan Medical Association Pub Date : 2025-08-25 DOI: 10.1016/j.jfma.2025.08.027

Tu Thai Bao Nguyen, Yi-Jie Kuo, Quang Son Tran, Yu-Pin Chen

引用次数: 0

Expert consensus on clinical usefulness of M2BPGi for managing chronic liver diseases. 专家对M2BPGi在慢性肝病治疗中的临床应用的共识

IF 2.5 3区医学

Journal of the Formosan Medical Association Pub Date : 2025-08-23 DOI: 10.1016/j.jfma.2025.08.022

Tai-Chung Tseng, Yao-Chun Hsu, Tung-Hung Su, Chen-Hua Liu, Chia-Chi Wang, Chih-Lin Lin, Hwai-I Yang, Yi-Hsiang Huang, Sheng-Shun Yang, Cheng-Yuan Peng, Tsung-Hui Hu, Jee-Fu Huang, Jia-Horng Kao

{"title":"Expert consensus on clinical usefulness of M2BPGi for managing chronic liver diseases.","authors":"Tai-Chung Tseng, Yao-Chun Hsu, Tung-Hung Su, Chen-Hua Liu, Chia-Chi Wang, Chih-Lin Lin, Hwai-I Yang, Yi-Hsiang Huang, Sheng-Shun Yang, Cheng-Yuan Peng, Tsung-Hui Hu, Jee-Fu Huang, Jia-Horng Kao","doi":"10.1016/j.jfma.2025.08.022","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.08.022","url":null,"abstract":"Chronic liver disease is a major global health concern, leading to fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Accurate fibrosis staging is essential for clinical management, yet liver biopsy remains invasive. Non-invasive tools such as transient elastography and serum biomarkers provide alternatives, but conventional markers like APRI and FIB-4 have limitations. Mac-2 binding protein glycosylation isomer (M2BPGi) has emerged as a novel biomarker for fibrosis assessment across various liver diseases. M2BPGi levels correlate with fibrosis severity in chronic hepatitis B, outperforming APRI and showing comparable performance to FIB-4, especially in patients with ALT flare-ups. Its predictive value for HCC has been shown in both untreated and treated CHB patients, with distinct cutoff values for risk stratification. In chronic hepatitis C, M2BPGi aids in fibrosis staging and predicts HCC occurrence post-sustained virologic response. In patients with metabolic dysfunction-associated steatotic liver disease, it correlates with advanced fibrosis and cirrhosis but requires further validation. While available literature supports the clinical utility of M2BPGi in managing chronic liver diseases, further research is needed to standardize cutoff values and expand validation across diverse populations, particularly in enhancing long-term HCC risk prediction for patients with MASLD and other chronic liver disease.","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reply to "Comment on risk of colon polyps and colorectal cancer in primary biliary cholangitis, a population-based retrospective cohort study in Taiwan". 回复“台湾原发性胆管炎患者发生结肠息肉及结直肠癌风险的回顾性队列研究”。

IF 2.5 3区医学

Journal of the Formosan Medical Association Pub Date : 2025-08-23 DOI: 10.1016/j.jfma.2025.08.029

Pei-Tzu Chen, Hsuan-Wei Chen

引用次数: 0

The associated factors of nutritional issues and body composition in Rett syndrome. Rett综合征中营养问题和身体成分的相关因素。

IF 2.5 3区医学

Journal of the Formosan Medical Association Pub Date : 2025-08-22 DOI: 10.1016/j.jfma.2025.08.026

Yen-Tsz Chen, Lee-Chin Wong, Shu-Mei Tsai, Pey-Rong Chen, Hsiu-Yu Shen, Wen-Che Tsai, Wang-Tso Lee

{"title":"The associated factors of nutritional issues and body composition in Rett syndrome.","authors":"Yen-Tsz Chen, Lee-Chin Wong, Shu-Mei Tsai, Pey-Rong Chen, Hsiu-Yu Shen, Wen-Che Tsai, Wang-Tso Lee","doi":"10.1016/j.jfma.2025.08.026","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.08.026","url":null,"abstract":"Individuals with Rett syndrome (RTT), a rare neurodevelopmental disorder, often face significant nutritional challenges. We explored factors affecting nutritional status and body composition in RTT individuals using dietary assessments and bioelectrical impedance analysis (BIA). This study involved 40 participants and found that underweight individuals with severe growth deficits often had reduced body fat, visceral fat, and arm circumference. Protein and zinc intake percentages were significantly lower in those with higher severity scores. Adolescents with the highest growth deficit and underweight ratios had caloric, protein, and calcium intakes below the Dietary Reference Intakes (DRI). Over 88 % of adults had insufficient calcium, magnesium, iron, zinc and fiber intake. Among the 15 females with RTT, sarcopenia was present in 14 (93.3 %), while sarcopenic obesity was present in 4 (26.67 %). Therefore, comprehensive dietary and body composition assessments, including body mass index, body fat, skeletal muscle, and mid-upper arm circumference, are crucial for identifying nutritional disorders in RTT. Addressing these issues through appropriate interventions is essential for improving nutritional management and outcomes for individuals with RTT.","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A consensus on the diagnosis and management of neurofibromatosis type 1 in Taiwan. 台湾1型神经纤维瘤病诊断与治疗的共识。

IF 2.5 3区医学

Journal of the Formosan Medical Association Pub Date : 2025-08-22 DOI: 10.1016/j.jfma.2025.08.018

I-Jun Chou, Pi-Chuan Fan, Chieh-Tsai Wu, Tu-Hsueh Yeh, Nan-Chang Chiu, Yen-Lin Liu, Yi-Hua Liao, Ming-Jen Lee, Chun-Chao Huang, Chuieng-Yi Lu, Tung-Ming Chang, Pi-Lien Hung, Ru-Li Lin, Kun-Long Hung, Huei-Shyong Wang, Kuang-Lin Lin

{"title":"A consensus on the diagnosis and management of neurofibromatosis type 1 in Taiwan.","authors":"I-Jun Chou, Pi-Chuan Fan, Chieh-Tsai Wu, Tu-Hsueh Yeh, Nan-Chang Chiu, Yen-Lin Liu, Yi-Hua Liao, Ming-Jen Lee, Chun-Chao Huang, Chuieng-Yi Lu, Tung-Ming Chang, Pi-Lien Hung, Ru-Li Lin, Kun-Long Hung, Huei-Shyong Wang, Kuang-Lin Lin","doi":"10.1016/j.jfma.2025.08.018","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.08.018","url":null,"abstract":"Neurofibromatosis type 1 (NF1) is a genetic disorder resulting from pathogenic variants in the tumor suppressor NF1 gene, which encodes neurofibromin. Its clinical manifestations are age-related and affect multiple systems, ranging from the characteristic café-au-lait macules, visible on the skin from birth, to plexiform neurofibromas (PNs), which have the potential to transform into malignant tumors during adolescence and adulthood. The Taiwan Child Neurology Society convened a series of meetings with experts from various specialties to review the latest evidence and updates related to NF1, including the recent approval of selumetinib for pediatric patients with symptomatic and inoperable PN in Taiwan. A consensus on diagnosis and management was established with the goal of enhancing disease understanding and providing guidance to local clinicians. Emphasis was placed on the importance of early recognition, diagnosis, and continuous health supervision, with the use of a multidisciplinary team (MDT) approach. It is recommended that a comprehensive benefit-risk assessment, considering all available treatment options, be conducted by the MDT to develop personalized management plans and ensure optimal care for pediatric NF1 patients.","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to comment on “Four decades of the RET gene: From discovery to tumor-agnostic therapy” 对“RET基因的四十年：从发现到肿瘤不可知论治疗”评论的回应。

IF 2.5 3区医学

Journal of the Formosan Medical Association Pub Date : 2025-08-21 DOI: 10.1016/j.jfma.2025.08.030

Masahide Takahashi

引用次数: 0

Real-world time-trend impact of rib fracture fixation on patients with multiple trauma using propensity score and ARIMA approaches. 使用倾向评分和ARIMA方法对多重创伤患者肋骨骨折固定的真实时间趋势影响。

IF 2.5 3区医学

Journal of the Formosan Medical Association Pub Date : 2025-08-21 DOI: 10.1016/j.jfma.2025.08.019

Wen-Ruei Tang, Chao-Chun Chang, Chih-Jung Wang, Tsung-Han Yang, Kuo-Shu Hung, Chun-Hsien Wu, Yi-Ting Yen, Yau-Lin Tseng, Yan-Shen Shan

{"title":"Real-world time-trend impact of rib fracture fixation on patients with multiple trauma using propensity score and ARIMA approaches.","authors":"Wen-Ruei Tang, Chao-Chun Chang, Chih-Jung Wang, Tsung-Han Yang, Kuo-Shu Hung, Chun-Hsien Wu, Yi-Ting Yen, Yau-Lin Tseng, Yan-Shen Shan","doi":"10.1016/j.jfma.2025.08.019","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.08.019","url":null,"abstract":"Background/purpose: Thoracic injuries, especially rib fractures, carry high morbidity and mortality. Surgical stabilization of rib fractures (SSRF) has emerged as a promising approach to reduce pulmonary complications. We aimed to analyze the benefits of SSRF beyond flail chest and make the study applicable to clinical practice.Methods: This study compared SSRF and conservative treatments at a tertiary trauma center. A time series analysis and propensity score matching were applied to evaluate the outcomes. Data from a trauma registry (January 2017 to December 2020) were used. Exclusion criteria included patients with non-salvageable injuries and those transferred after 72 h. Primary outcomes were ventilator-free days on day 28 (VFD28) and non-procedural pulmonary complications (NPRCs).Results: Of 770 eligible patients, 692 were enrolled, with 164 undergoing SSRF. SSRF patients had significantly longer VFD28 (22.5 vs. 19.0; P = 0.042) and reduced NPRCs (8.0 % vs. 14.5 %; P = 0.086). Subgroup analysis showed that SSRF patients requiring mechanical ventilation had longer ICU-free days (IFD28) and hospital-free days (HFD90) and lower mortality rates. Those not receiving ventilation but with more than three rib fractures also benefited from SSRF in terms of reduced NPRCs.Conclusion: SSRF improved clinical outcomes in more than just flail chest cases, benefiting patients with multiple rib fractures, both with and without mechanical ventilation. These findings support the broader clinical application of SSRF.","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on "Genetic and clinical characteristics of catecholaminergic polymorphic ventricular tachycardia in a Taiwanese nationwide cohort". 评论“台湾全国性队列中儿茶酚胺能多态性室性心动过速的遗传和临床特征”。

IF 2.5 3区医学

Journal of the Formosan Medical Association Pub Date : 2025-08-20 DOI: 10.1016/j.jfma.2025.08.005

Ranjana Sah, Rachana Mehta

引用次数: 0

2024 Taiwan clinical practice guideline for diabetic kidney disease - an executive summary. 2024台湾糖尿病肾病临床实践指南-执行摘要。

IF 2.5 3区医学

Journal of the Formosan Medical Association Pub Date : 2025-08-20 DOI: 10.1016/j.jfma.2025.08.020

Sheng-Chiang Su, Tieng-Chun Chang, Yi-Wen Chiu, Chih-Hsun Chu, Yueh-Han Hsu, Chin-Sung Kuo, Chun-Chuan Lee, Ming-Hsun Lin, Chun-Liang Lin, Yuh-Feng Lin, Da-Wei Lin, Hui-Yu Peng, Shwu-Pyng Su, Yi-Chun Tsai, Yao-Hsien Tseng, Jun-Sing Wang, Tsai-Jung Wang, Yi-Sun Yang, Chien-Ning Huang, Horng-Yih Ou, Mai-Szu Wu

{"title":"2024 Taiwan clinical practice guideline for diabetic kidney disease - an executive summary.","authors":"Sheng-Chiang Su, Tieng-Chun Chang, Yi-Wen Chiu, Chih-Hsun Chu, Yueh-Han Hsu, Chin-Sung Kuo, Chun-Chuan Lee, Ming-Hsun Lin, Chun-Liang Lin, Yuh-Feng Lin, Da-Wei Lin, Hui-Yu Peng, Shwu-Pyng Su, Yi-Chun Tsai, Yao-Hsien Tseng, Jun-Sing Wang, Tsai-Jung Wang, Yi-Sun Yang, Chien-Ning Huang, Horng-Yih Ou, Mai-Szu Wu","doi":"10.1016/j.jfma.2025.08.020","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.08.020","url":null,"abstract":"Scientific advances and development in the management of diabetes including use of new glucose-lowering agents for cardiorenal protection in diabetic patients prompted revision of local clinical practice guideline for diabetic kidney disease (DKD). Multiple cross-disciplinary professional meetings were held in 2023 and 2024 by experts from the Diabetes Association of the Republic of China (Taiwan), the Taiwanese Association of Diabetes Educators and the Taiwan Society of Nephrology to review the latest evidence and to develop updated recommendations, taking local epidemiology, circumstances and relevant local guidelines into considerations. From screening and diagnosis; risk classification and monitoring; lifestyle modifications; glycemic, blood pressure and lipid management; to the use of cardiorenal protective medications and complication management, the 2024 Taiwan Clinical Practice Guideline for DKD aims to offer up-to-date reference and comprehensive guidance to local practitioners for optimization of DKD patient care.","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on: "Red cell distribution width as an inflammatory biomarker for predicting one-year survival after geriatric hip fracture". 评论：“红细胞分布宽度作为预测老年髋部骨折后一年生存率的炎症生物标志物”。

IF 2.5 3区医学

Journal of the Formosan Medical Association Pub Date : 2025-08-18 DOI: 10.1016/j.jfma.2025.08.023

Yi Lu, Hao Jiang, Jiaxin Bao

引用次数: 0