Shuaibu Abdullahi Hudu, Emad A Morad, Ghusun M Alhazimi, Abdulgafar Olayiwola Jimoh
{"title":"Response to \"From promising signatures to clinically credible prediction: Strengthening microbiome-metabolome prognostic research\".","authors":"Shuaibu Abdullahi Hudu, Emad A Morad, Ghusun M Alhazimi, Abdulgafar Olayiwola Jimoh","doi":"10.1016/j.jfma.2026.09.012","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.09.012","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148920306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Taiwan joint consensus on the management of osteoporosis in patients with diabetes.","authors":"Jawl-Shan Hwang, Jung-Fu Chen, Shih-Te Tu, Chih-Hsing Wu, Chih-Yuan Wang, Der-Sheng Han, Chun-Chuan Lee, Chung-Mei Ouyang, Shu-Mei Chen, Chung-Hwan Chen, Feng-Hsuan Liu, Horng-Yih Ou","doi":"10.1016/j.jfma.2026.08.051","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.08.051","url":null,"abstract":"<p><p>Diabetes mellitus is increasingly recognized as a major contributor to skeletal fragility. Diabetes-related factors, including alterations in bone microarchitecture and heightened fall risk, contribute to an increased risk of fragility fractures regardless of bone mineral density. To address the distinct challenges in managing bone health in diabetes, the Taiwanese Association of Diabetes Educators, in collaboration with the Taiwanese Osteoporosis Association and the Endocrine Society of the Republic of China, established an expert committee to develop consensus statements based on major existing guidelines, current evidence, and expert opinion. Early screening for osteoporosis should be considered for individuals with diabetes, and adjustments to risk calculation may be needed to avoid underestimation of fracture risk. Nonpharmacologic management is a key component of optimizing bone health. Current evidence supports that anti-osteoporosis treatments demonstrate similar efficacy in individuals with and without diabetes, although certain agents may improve glycemic parameters. Selection of antihyperglycemic therapy requires consideration of potential positive or negative impact on bone mineral density and fracture risk. System-level strategies are needed to enhance multidisciplinary collaboration, heighten awareness, support systematic management, and integrate bone health into routine care. This consensus aims to provide a practical, evidence-based approach to optimize bone health in this high-risk population.</p>","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148920325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Long-term effect of AST-120 on delaying renal replacement therapy initiation in CKD: A propensity score overlap-weighted retrospective cohort study\".","authors":"Hongquan Liu, Fengze Sun, Jian Ma, Jitao Wu","doi":"10.1016/j.jfma.2026.09.010","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.09.010","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148920260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tzu-Hsuan Su, Pei-Lung Chen, Steven Shinn-Forng Peng, Chi-Yung Shang, Chia-Wei Lin, Pi-Chuan Fan
{"title":"Long-term seizure outcomes and factors associated with response to adjunctive everolimus in TSC-associated epilepsy.","authors":"Tzu-Hsuan Su, Pei-Lung Chen, Steven Shinn-Forng Peng, Chi-Yung Shang, Chia-Wei Lin, Pi-Chuan Fan","doi":"10.1016/j.jfma.2026.09.003","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.09.003","url":null,"abstract":"<p><strong>Background: </strong>Everolimus, a mechanistic target of rapamycin (mTOR) inhibitor, is increasingly used in tuberous sclerosis complex (TSC)-associated epilepsy; however, long-term real-world outcomes and factors associated with favorable response remain unclear. This study aimed to evaluate the long-term seizure outcomes of adjunctive everolimus and explore clinical factors associated with treatment response.</p><p><strong>Methods: </strong>We retrospectively recruited 21 patients with active TSC-associated epilepsy receiving adjunctive everolimus and assessed seizure outcomes during follow-up. Clinical characteristics were compared between responders and non-responders at 1 year after treatment initiation.</p><p><strong>Results: </strong>Over a median treatment duration of 72 months, responder rates ranged from 53.8% to 64.7%, and seizure-free rates ranged from 33.3% to 41.2%. Responders had fewer involved organ systems at baseline (median 3 vs. 4, p = 0.020) and lower anti-seizure medication burden (median 2 vs. 4, p = 0.045). Younger age at treatment initiation showed a trend toward improved response.</p><p><strong>Conclusion: </strong>Adjunctive everolimus was associated with sustained long-term seizure reduction in this real-world cohort. In exploratory analyses, fewer involved organ systems and fewer baseline ASMs were associated with favorable treatment response. These findings require validation in larger prospective cohorts.</p>","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148920280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Impact of computed tomography noise and region of interest sizes on the characterization of homogeneous renal mass: a proof-of-concept study\".","authors":"Hongquan Liu, Fengze Sun, Jian Ma, Jitao Wu","doi":"10.1016/j.jfma.2026.09.011","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.09.011","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148912703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Annual cholangitis more than twice predicts liver transplant in biliary atresia patients who achieve jaundice-free after Kasai portoenterostomy\".","authors":"Wei Li, Yufang Deng","doi":"10.1016/j.jfma.2026.08.045","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.08.045","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148912700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Corrigendum to \"Prevalence, risk factors, and management of adult asthma in Taipei: A global asthma network phase I survey\".","authors":"Jui-Che Tsai, Kuo-Wei Yeh, Dah-Chin Yan, Liang-Shiou Ou, Chao-Yi Wu, Li-Lun Lin, Shu-Jung Huang, Tsung-Chieh Yao, Jing-Long Huang, Kuan-Wen Su","doi":"10.1016/j.jfma.2026.09.005","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.09.005","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148912697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on 'Invasive fungal rhinosinusitis: experience from a 4-year case series of 49 adult patients at a tertiary hospital in Vietnam'.","authors":"Yiliang Huang, Luping Zhang","doi":"10.1016/j.jfma.2026.09.001","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.09.001","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Real-world outcomes after biologic-to-biologic switching to dupilumab in adult asthma: A retrospective single-center cohort study\".","authors":"Xiang Zhou, Xiangwen Gong","doi":"10.1016/j.jfma.2026.09.002","DOIUrl":"https://doi.org/10.1016/j.jfma.2026.09.002","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}