Journal of Surgical Oncology最新文献_第4页

PIPAC Pharmacologic and Clinical Data. PIPAC 药理和临床数据。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-09-24 DOI: 10.1002/jso.27900

Delia Cortés-Guiral, Onno Kranenburg, Olivia Sgarbura, Kurt Van Der Speeten, Albdelkader Taibi, Martin Hübner, Almog Ben Yacoov

引用次数: 0

Collateralization of the upper extremity lymphatic system after axillary lymph node dissection. 腋窝淋巴结清扫术后上肢淋巴系统的侧支。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-09-24 DOI: 10.1002/jso.27827

James E Fanning, David K V Chung, Hayley M Reynolds, Tharanga D Jayathungage Don, Hiroo Suami, Kevin J Donohoe, Dhruv Singhal

{"title":"Collateralization of the upper extremity lymphatic system after axillary lymph node dissection.","authors":"James E Fanning, David K V Chung, Hayley M Reynolds, Tharanga D Jayathungage Don, Hiroo Suami, Kevin J Donohoe, Dhruv Singhal","doi":"10.1002/jso.27827","DOIUrl":"https://doi.org/10.1002/jso.27827","url":null,"abstract":"Background: Lymphatic drainage from the arm may be altered after axillary lymph node dissection (ALND). Understanding these alterations is important as they may change standard surgical and radiation treatment in recurrent breast cancer or upper extremity skin cancers, including melanoma.Methods: Utilizing a single-institution planar and single photon emission computed tomography/computed tomography lymphoscintigraphy database, we identified patients with a diagnosis of upper extremity cutaneous melanoma from 2008 to 2023 who previously underwent ALND for cancer treatment and did not develop upper extremity cancer-related lymphedema. ALND patients were matched to control patients presenting with cutaneous melanomas at the same anatomic sites. Sentinel lymph nodes (SLNs) were compared between both groups.Results: Of 3628 upper extremity melanoma cutaneous patients, 934 met inclusion criteria, including 22 ALND and 912 control patients. Level I axillary SLN drainage was observed in 98% of controls and 27% of ALND patients (p < 0.001). Level II axillary SLN drainage was observed in 3% of controls and 27% of ALND patients (p < 0.001). Level III axillary SLN drainage was observed in 1% of controls and 32% of ALND patients (p < 0.001). Epitrochlear SLN drainage was observed in 9% of controls and 32% of ALND patients, respectively (p < 0.046). Brachial SLN drainage was observed in 4% of controls and 23% of ALND patients (p < 0.001).Conclusions: Distinct changes in functional lymphatic drainage were seen between the arms of patients who previously underwent ALND versus control patients. Levels II and III axillary, epitrochlear, and brachial nodes are possible sites of metastatic disease that should be considered in patients with a prior ALND.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142308006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Commentary on "Preoperative Chemotherapy Response and Survival in Patients With Colorectal Cancer Peritoneal Metastases". 关于 "结直肠癌腹膜转移患者术前化疗反应和生存率 "的评论。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-09-24 DOI: 10.1002/jso.27929

Chong-Jie Zhang

引用次数: 0

Comment On: "Acupuncture Treatment for Liver Cancer Pain: A Meta-Analysis". 关于 "针灸治疗肝癌疼痛：一项 Meta 分析 "的评论

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-09-20 DOI: 10.1002/jso.27918

Menglin Chen, Hua Zhao, Ling He

引用次数: 0

Barriers to Offering Organ Preservation for Rectal Cancer in a Predominantly Hispanic Safety Net Hospital. 在一家以西班牙裔为主的安全网医院为直肠癌患者提供器官保留治疗的障碍。

IF 2.5 3区医学

Journal of Surgical Oncology Pub Date : 2024-09-19 DOI: 10.1002/jso.27893

Bilal W Nasim,Samantha Murphy,Jaclyn Yracheta,Austen Lee Clark,Shriya L Veluri,Venkata Katabathina,Alexander Parikh,Haisar Dao Campi,Yael Feferman,Tara A Russell,Sukeshi P Arora,Neil Newman,Alicia J Logue,Colin M Court

{"title":"Barriers to Offering Organ Preservation for Rectal Cancer in a Predominantly Hispanic Safety Net Hospital.","authors":"Bilal W Nasim,Samantha Murphy,Jaclyn Yracheta,Austen Lee Clark,Shriya L Veluri,Venkata Katabathina,Alexander Parikh,Haisar Dao Campi,Yael Feferman,Tara A Russell,Sukeshi P Arora,Neil Newman,Alicia J Logue,Colin M Court","doi":"10.1002/jso.27893","DOIUrl":"https://doi.org/10.1002/jso.27893","url":null,"abstract":"BACKGROUNDTotal neoadjuvant therapy (TNT) for locally advanced rectal cancer (LARC) has shown promise in achieving pathologic complete response (pCR) and enabling organ preservation through watch-and-wait (WW) strategies. However, implementation of WW protocols in diverse patient populations and safety-net hospitals faces unique challenges. The objective of this study is to evaluate TNT outcomes and identify barriers to WW implementation in a predominantly Hispanic safety-net hospital in South Texas.METHODSA retrospective review was conducted of 40 LARC patients treated with TNT at an academic tertiary referral center in South Texas between 2018 and 2023. Patient demographics, disease characteristics, and pCR rates were analyzed. A survey of multidisciplinary providers assessed perceived institutional and patient-related barriers to WW implementation.RESULTSThe cohort was 70% Hispanic, with a median age of 54 years. Most patients had advanced disease at diagnosis (57.5% T4, 65% N2). The pCR rate was 18.5% (5/27) among patients undergoing surgery. Re-review of MRIs for pCR patients revealed that 2/5 had minimal residual disease. The provider survey identified MRI quality variability, lack of dedicated treatment coordinators, and concerns about patient compliance and financial barriers as key obstacles to WW implementation.CONCLUSIONSDespite advanced disease presentation in a predominantly Hispanic population, TNT achieved pCR rates comparable to international trials. Institutional and patient-level barriers to WW were identified, informing the development of a tailored WW protocol for this unique patient population.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142258226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Proportion of Patients With Ductal Carcinoma In Situ That Qualify for Observation Criteria Set Forth by Clinical Trials. 符合临床试验观察标准的原位导管癌患者比例。

IF 2.5 3区医学

Journal of Surgical Oncology Pub Date : 2024-09-19 DOI: 10.1002/jso.27858

Callie D McAdams,Nicholas Clevenger,Kyra Nicholson,Catherine Pesce,Katherine Kopkash,Elizabeth Poli,Thomas W Smith,Katherine Yao

{"title":"Proportion of Patients With Ductal Carcinoma In Situ That Qualify for Observation Criteria Set Forth by Clinical Trials.","authors":"Callie D McAdams,Nicholas Clevenger,Kyra Nicholson,Catherine Pesce,Katherine Kopkash,Elizabeth Poli,Thomas W Smith,Katherine Yao","doi":"10.1002/jso.27858","DOIUrl":"https://doi.org/10.1002/jso.27858","url":null,"abstract":"BACKGROUNDThe COMET, LORD, and LORIS clinical trials are investigating the role of active surveillance in low-risk ductal carcinoma in situ (DCIS). The objective of this study was to identify the proportion of patients eligible for these trials amongst a cohort of patients treated at our institution.METHODSRetrospective chart review was performed of patients diagnosed with DCIS who were treated from 2013 to 2022. Clinical, tumor, and imaging inclusion and exclusion criteria of the aforementioned observation trials were applied to determine the proportion of patients eligible for each trial. Upgrade rate to invasive cancer were examined across all three groups.RESULTSOf 1223 patients diagnosed with DCIS, applying the criteria of each trial, 245 (20%), 238 (19.4%), and 264 (21.6%) patients were eligible for the COMET, LORD, and LORIS trials, respectively. High-grade DCIS and mass on imaging had the largest impact on exclusion. Nineteen (7.8%) of women who qualified for COMET were upgraded to invasive disease at excision, compared to 18 (7.6%) for LORD, and 19 (7.2%) for LORIS.CONCLUSIONSOne in five patients diagnosed with DCIS at our institution would qualify for observation with current trial eligibility. Observation of DCIS may have limited impact on all DCIS patients.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142258261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Colorectal cancer care continuum: Navigating screening, treatment, and outcomes disparities. 大肠癌护理的连续性：引导筛查、治疗和结果差异。

IF 2.5 3区医学

Journal of Surgical Oncology Pub Date : 2024-09-19 DOI: 10.1002/jso.27848

Adelso Tejada Jackson,Olajumoke Megafu,Diri Abdullahi,Robert Amajoyi

引用次数: 0

Impact of Minimally Invasive Surgery on Early and Late Outcomes of Patients With Gastric Cancer Treated Using Neoadjuvant Chemotherapy. 微创手术对采用新辅助化疗的胃癌患者早期和晚期疗效的影响

IF 2.5 3区医学

Journal of Surgical Oncology Pub Date : 2024-09-19 DOI: 10.1002/jso.27904

Gustavo Ferreira Araruna,Heber S C Ribeiro,Silvio M Torres,Alessandro L Diniz,André L Godoy,Igor C Farias,Wilson L Costa,Felipe J F Coimbra

{"title":"Impact of Minimally Invasive Surgery on Early and Late Outcomes of Patients With Gastric Cancer Treated Using Neoadjuvant Chemotherapy.","authors":"Gustavo Ferreira Araruna,Heber S C Ribeiro,Silvio M Torres,Alessandro L Diniz,André L Godoy,Igor C Farias,Wilson L Costa,Felipe J F Coimbra","doi":"10.1002/jso.27904","DOIUrl":"https://doi.org/10.1002/jso.27904","url":null,"abstract":"BACKGROUNDGastric cancer is the fifth most common neoplasm and the third leading cause of cancer-related death worldwide. Neoadjuvant chemotherapy is recommended for Stages II-III resectable tumors, but the comparative effectiveness of minimally invasive surgery (MIS) versus open gastrectomy (OG) post-neoadjuvant therapy has not been adequately investigated.METHODSA retrospective cohort analysis was performed on patients with clinical Stage II and III gastric adenocarcinoma who underwent neoadjuvant chemotherapy followed by either MIS or OG between 2007 and 2020. Propensity score matching was utilized to compare the clinical and surgical outcomes, morbidity, and mortality, and the influence of MIS on 3-year survival rates was evaluated.RESULTSAfter matching, no statistical differences in clinical aspects were noted between the two groups. MIS was associated with increased D2 lymphadenectomy, curative intent, and complete neoadjuvant therapy. Furthermore, this therapeutic approach resulted in reduced transfusion rates and shorter hospital stays. Nonetheless, no significant differences were observed in global, clinical, or surgical complications or mortality between the two groups. Weight loss emerged as a significant risk factor for complications, but MIS did not independently affect survival rates. Extended resection and higher American Society of Anesthesiology scores were independent predictors of reduced survival.CONCLUSIONMIS after neoadjuvant chemotherapy for gastric cancer appears to be a viable option, with oncological outcomes comparable to those of OG, less blood loss, and shorter hospital stays. Although MIS did not independently affect long-term survival, it offered potential benefits in terms of postoperative recovery and morbidity. Further studies are needed to validate these findings, especially across diverse populations.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142258260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Association of Taxanes With Breast Cancer-Related Lymphedema. 紫杉类药物与乳腺癌相关淋巴水肿的关系

IF 2.5 3区医学

Journal of Surgical Oncology Pub Date : 2024-09-19 DOI: 10.1002/jso.27906

Kadri Altundag

引用次数: 0

Robotic and Laparoscopic Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy, Multicenter Study From Saudi Arabia. 沙特阿拉伯多中心研究：机器人和腹腔镜细胞再生手术及腹腔内热化疗

IF 2.5 3区医学

Journal of Surgical Oncology Pub Date : 2024-09-19 DOI: 10.1002/jso.27902

Mohammad Alyami,Abdullah Muhammed Abdulrahem,Mashhour Alqannas,Hessa AlHabes,Awad Alyami,Sulaiman Alshammari,Delia Cortes Guiral,Mahdi Alzamanan,Nayef Alzahrani,Thamer Bin Traiki

{"title":"Robotic and Laparoscopic Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy, Multicenter Study From Saudi Arabia.","authors":"Mohammad Alyami,Abdullah Muhammed Abdulrahem,Mashhour Alqannas,Hessa AlHabes,Awad Alyami,Sulaiman Alshammari,Delia Cortes Guiral,Mahdi Alzamanan,Nayef Alzahrani,Thamer Bin Traiki","doi":"10.1002/jso.27902","DOIUrl":"https://doi.org/10.1002/jso.27902","url":null,"abstract":"BACKGROUNDPeritoneal metastasis (PM) is a common evolution of abdominal tumors. Without aggressive multimodal treatment, it is associated with a poor prognosis. The aim of this study is to present a multicenter results from Saudi Arabia on minimally invasive CRS and HIIPEC.METHODSA retrospective analysis of a prospective maintained multicenter database was queried for all patients treated with laparoscopic or robotic CRS and HIPEC between 2019 and 2024 in Saudi Arabia. Surgical and oncological outcome was analyzed.RESULTSEleven consecutive patients underwent minimally invasive CRS and HIPEC between 2019 and 2024. Eight patients (72.7%) were operated by laparoscopy, one of them by single port access and three patients (27.3%) were operated robotically. Six patients (54.5%) were female. Median age was 42 (29-64). Primary tumor was PMP from the appendix, colon, and MCM in 6 (54.5%), 4 (36.4%), and 1 (9.1%) respectively. The median duration to complete the surgical procedure for all patients was 330 (230-580) min and for robotic CRS the median docking time was 570 (330-580) min. Median PCI was 2 (1-7) and completeness Cytoreduction (CC score 0) was achieved in the all patients (100%). Median hospital stay was 8 days (3-20). Four patients had one night postoperative ICU stay. Major morbidity (CTCAE) 3 and 4 occurred in three patients (27.3%) (Port site hernia, bleeding, and wound infection). No readmission to the hospital and no 90 days mortalities.CONCLUSIONThe minimally invasive approach by laparoscopy or robot is a feasible and promising option for CRS and HIPEC. It reduces the hospital stay, early return to intended oncological treatment (RIOT). Further prospective clinical studies are needed to evaluate this approach.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142258264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0