{"title":"Comment On: \"Patient and Surgeon Attitudes Toward Opportunistic Salpingectomy During Nongynecological Surgeries for the Prevention of Ovarian Cancer: A Qualitative Study\".","authors":"Yadan Yao, Yuanxin Fu","doi":"10.1002/jso.28130","DOIUrl":"https://doi.org/10.1002/jso.28130","url":null,"abstract":"","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Phase I/II Trial of Perioperative Avelumab in Combination With Chemoradiation in the Treatment of Stage II/III Resectable Esophageal and Gastroesophageal Junction Cancer\".","authors":"Chengsen Liu, Jiandong Cao","doi":"10.1002/jso.28127","DOIUrl":"https://doi.org/10.1002/jso.28127","url":null,"abstract":"","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Reducing Postoperative Opioid Use: A Comparison of Open Versus Ultrasound-Guided Regional Anesthesia for Patients Undergoing Open Pancreatoduodenectomy\".","authors":"Chengsen Liu, Jiandong Cao","doi":"10.1002/jso.28128","DOIUrl":"https://doi.org/10.1002/jso.28128","url":null,"abstract":"","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Potential Factors Limiting Consistency of AI Imaging Recommendations and Multidisciplinary Tumor Boards.","authors":"Wenhan Wu","doi":"10.1002/jso.28129","DOIUrl":"https://doi.org/10.1002/jso.28129","url":null,"abstract":"","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"ChatGPT 35 Better Improves Comprehensibility of English, Than Spanish, Generated Responses to Osteosarcoma Questions\".","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.1002/jso.28124","DOIUrl":"https://doi.org/10.1002/jso.28124","url":null,"abstract":"","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment On: \"ChatGPT 35 Better Improves Comprehensibility of English, Than Spanish, Generated Responses to Osteosarcoma Questions\".","authors":"Renjie Huang, Hong Song","doi":"10.1002/jso.28132","DOIUrl":"https://doi.org/10.1002/jso.28132","url":null,"abstract":"","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charlotte F Wahle, Nicole J Newman-Hung, Sara Sakowitz, Noah Federman, Arun S Singh, Nicholas M Bernthal, Peyman Benharash, Lauren E Wessel
{"title":"Neoadjuvant Chemotherapy Is Associated With Reduced Amputation Risk in Synovial Sarcoma of the Lower Extremity.","authors":"Charlotte F Wahle, Nicole J Newman-Hung, Sara Sakowitz, Noah Federman, Arun S Singh, Nicholas M Bernthal, Peyman Benharash, Lauren E Wessel","doi":"10.1002/jso.28143","DOIUrl":"https://doi.org/10.1002/jso.28143","url":null,"abstract":"<p><strong>Background and objectives: </strong>The combination of radiation and surgical resection represents the current standard of care for primary synovial sarcoma (SS). However, controversy remains regarding the role of chemotherapy. We sought to evaluate the impact of neoadjuvant chemotherapy on the likelihood of undergoing amputation for patients with lower extremity SS.</p><p><strong>Methods: </strong>We identified all adults (≥ 18 years) diagnosed with nonmetastatic SS of the lower extremity who underwent definitive resection within the 2004-2021 National Cancer Database. Multivariable models were developed to assess the independent association of neoadjuvant chemotherapy with likelihood of amputation versus limb salvage. We secondarily considered the independent association of neoadjuvant treatment or amputation with overall survival at 5 years.</p><p><strong>Results: </strong>Of 1207 patients, 376 (31%) received neoadjuvant chemotherapy. Patients who received neoadjuvant treatment were younger and more commonly presented with Stage III disease. Following comprehensive adjustment for patient, disease, and hospital factors, receipt of neoadjuvant chemotherapy was linked with significantly reduced likelihood of amputation (AOR 0.47, CI 0.27-0.84). Upon risk-adjusted survival analysis, receipt of neoadjuvant therapy was linked with similar outcomes, but amputation was associated with significantly greater mortality hazard over 5 years following resection (HR 1.75, CI 1.30-2.35).</p><p><strong>Conclusions: </strong>In this national registry study, receipt of neoadjuvant chemotherapy was associated with significantly reduced odds of amputation. Amputation was linked with significantly greater mortality over 5 years while neoadjuvant chemotherapy did not improve 5-year overall survival.</p>","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kelly R Bates, Norah N Zaza, Dominic J Vitello, Hannah Bentrem, Steven J Stryker, Rajesh N Keswani, Charles D Logan
{"title":"Low Rates of Digital Rectal Exam in an Academic Health System Represent a Missed Opportunity.","authors":"Kelly R Bates, Norah N Zaza, Dominic J Vitello, Hannah Bentrem, Steven J Stryker, Rajesh N Keswani, Charles D Logan","doi":"10.1002/jso.28160","DOIUrl":"https://doi.org/10.1002/jso.28160","url":null,"abstract":"<p><strong>Background and objectives: </strong>Digital rectal exam (DRE) is an important screening tool for early cancer identification. DRE has become less routinely performed following removal from cancer screening guidelines. The effect of this decreased utilization has not been studied; this study sought to evaluate current DRE utilization and changes over time.</p><p><strong>Methods: </strong>The electronic medical record database of a regional academic health system was assessed between 2015 and 2020 for encounters with patients aged 45-75. DRE rates and yearly trends were assessed using chi-squared and Cochran-Armitage tests, respectively.</p><p><strong>Results: </strong>Of 191 329 outpatient encounters, DRE was documented on 8.5% of visits. DRE utilization declined from 2015 to 2020 (9.6% vs. 8.9%). DRE was more often identified as a procedure in surgical specialties, including surgical oncology (55.6%) and general surgery (2.8%), compared to primary care specialties, including family medicine (1.7%) and internal medicine (1.6%). DREs were less frequently documented for non-Hispanic Black patients versus non-Black patients (7.2% vs. 8.4%) and for Hispanic patients versus Non-Hispanic White patients (7.6% vs. 8.5%). Men had a documented DRE procedure more frequently than women overall (10.4% vs. 4.6%) and in encounters with primary care specialties (2.3% vs. 0.5%) and surgical specialties (20.4% vs. 13.5%) (all p < 0.001).</p><p><strong>Conclusions: </strong>In this contemporary evaluation, DRE was less frequently coded during outpatient clinic visits overall and specifically in primary care compared with surgical specialties. Differences in DRE utilization across sociodemographic factors highlight disparities in cancer screening. Low DRE rates represent a missed opportunity for early identification of high prevalence cancers.</p>","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erlon de Avila Carvalho, Rachid Eduardo Noleto da Nobrega Oliveira, José Henrique Agner Ribeiro, Jefferson Luís Gross, Cezar Augusto Vendas Galhardo, Heládio Feitosa E Castro Neto, Giovana Dos Santos, Reitan Ribeiro, Alexandre Ferreira Oliveira, Rodrigo Nascimento Pinheiro
{"title":"Malignant Pleural Effusion: Palliative Managements and Indication for Pleurodesis Based on Survival Scores.","authors":"Erlon de Avila Carvalho, Rachid Eduardo Noleto da Nobrega Oliveira, José Henrique Agner Ribeiro, Jefferson Luís Gross, Cezar Augusto Vendas Galhardo, Heládio Feitosa E Castro Neto, Giovana Dos Santos, Reitan Ribeiro, Alexandre Ferreira Oliveira, Rodrigo Nascimento Pinheiro","doi":"10.1002/jso.28156","DOIUrl":"https://doi.org/10.1002/jso.28156","url":null,"abstract":"<p><p>Neoplastic pleural effusion is one in which malignant neoplastic cells are detected in the pleural fluid or in the parietal pleura. When secondary, it confirms disseminated neoplastic disease and suggests a reduced life expectancy and low quality of life. This review was described by a group of physician members of the Brazilian Society of Oncological Surgery regarding the treatment of neoplastic pleural effusion, developed to guide surgeons, palliative care physicians and clinical oncologists in their clinical practice to assess patients indicated for pleurodesis based on survival scores.</p>","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Spencer G Van Decar, Elizabeth L Barbera, Alexandra M Adams, Jason M Shore, Iulian B Dragusin, Erika A Davis, Craig A Tork, Robert Krell, Troy B Graybeal, Katherine Clifton, Arianna Buckley, G Travis Clifton
{"title":"A Validated Ultrasound-Based Scoring System to Stratify Risk of Axillary Metastasis in Breast Cancer: AX-RADS (Axillary Imaging Reporting and Data System).","authors":"Spencer G Van Decar, Elizabeth L Barbera, Alexandra M Adams, Jason M Shore, Iulian B Dragusin, Erika A Davis, Craig A Tork, Robert Krell, Troy B Graybeal, Katherine Clifton, Arianna Buckley, G Travis Clifton","doi":"10.1002/jso.28159","DOIUrl":"https://doi.org/10.1002/jso.28159","url":null,"abstract":"<p><strong>Introduction: </strong>Ultrasound is the imaging modality of choice for evaluation of axillary involvement in breast cancer, but is associated with variable sensitivity and specificity. Understanding the risk of axillary lymph node metastasis (ALNM) based on ultrasonographic and clinical features will inform treatment decisions. Our group aimed to create a scoring system to quantify the risk of ALNM based on ultrasound characteristics in breast cancer patients. We validated the model and tested it among different Memorial Sloan Kettering Breast Cancer Sentinel Lymph Node Metastasis Nomogram (MSK) subgroups.</p><p><strong>Methods: </strong>The ultrasound score was developed using data collected at a single institution from 2019 to 2021 by allocating points based on the regression coefficients of variables found to significantly predict ALNM. We validated the test statistics of our score at an outside institution. The index and validation cohorts were combined: 358 pooled patients were stratified by predicted ALNM positivity according to a validated nomogram based on primary tumor characteristics.</p><p><strong>Results: </strong>Between 2019 and 2021, in the validation cohort, the NPV for low risk (0-1) scores was 87%, while the PPV for high-risk (5 +) scores was 71%. Overall, in the combined cohort, 241 (67%) patients had low-risk (0-1) axillary ultrasound scores and 33 (9%) had high risk (5 +) scores. In this combined cohort, NPV was 84% (203/241 low-risk score patients were node negative), while PPV for high-risk scores was 85% (28/33 high-risk score patients were node positive). When stratified via the Memorial Sloan Kettering Breast Cancer Nomogram: Sentinel Lymph Node Metastasis predicted ALNM rates, the NPV of low-risk scores was 87%-89% for patients with < 50% predicted ALNM positivity. For patients with > 50% predicted ALNM positivity, the PPV of high-risk scores was 82%.</p><p><strong>Conclusions: </strong>A scoring system to predict ALNM among biopsy-proven breast cancer patients undergoing upfront surgery was successfully developed from a multivariate model based on axillary ultrasound characteristics. Combining the axillary US scoring system with an additional validated nomogram based on primary tumor and patient characteristics may help foster better communication about ALNM risk to inform treatment decisions.</p>","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}