Claudia A. Vega-Cázarez, D. Sánchez‐Machado, J. López‐Cervantes
{"title":"Overview of Electrospinned Chitosan Nanofiber Composites for Wound Dressings","authors":"Claudia A. Vega-Cázarez, D. Sánchez‐Machado, J. López‐Cervantes","doi":"10.5772/INTECHOPEN.76037","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.76037","url":null,"abstract":"Chitosan has a medical application because of its natural origin and properties of bio- degradability, biocompatibility, nontoxicity, and antimicrobial capacity. Electrospinning produces non-woven nanofibers to wound dressing with high specific surface area and small pores. These properties are favorable for absorption of exudates and prevent the penetration of bacteria, thus promoting wound healing. For this reason, chitosan blends are used to produce nanofiber dressings, and the characterization of the structural, mechanical, and biological properties is very promising for further studies. Nowadays, the researchers are seeking for biomaterials that provide modern dressings with many qualities, which are designed to promote wound healing. In this chapter, the electrospin- ning parameters that affect the nanofiber properties based on chitosan to prepare wound dressings are highlighted.","PeriodicalId":170888,"journal":{"name":"Chitin-Chitosan - Myriad Functionalities in Science and Technology","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134585304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chitosan: A Good Candidate for Sustained Release Ocular Drug Delivery Systems","authors":"L. Popa, M. Ghica, C. Dinu-Pîrvu, Teodora Irimia","doi":"10.5772/INTECHOPEN.76039","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.76039","url":null,"abstract":"This chapter focuses on the eye, one of the most important organs of humans. Current data on pathophysiology of the human eye are presented in direct correlation with a range of therapeutic products, with a well-known and widely used material, namely chitosan. Applications of chitosan biopolymer are described in the development of innovative, modern, therapeutic devices and solutions. Thus, chitosan is a good excipient either for classic drop-type ocular systems, as well as for complex drug systems such as nanostructures (nanoparticles, nanomicelles and nanosuspensions), liposomes, microemulsions, microspheres, in situ hydrogels and inserts or implants. A number of disadvantages for ocular administration of the drugs are thus overcome.","PeriodicalId":170888,"journal":{"name":"Chitin-Chitosan - Myriad Functionalities in Science and Technology","volume":"116 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123206130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Verma, Arumugam Madhan Kumar, M. Mazumder, M. Quraishi
{"title":"Chitosan-Based Green and Sustainable Corrosion Inhibitors for Carbon Steel","authors":"C. Verma, Arumugam Madhan Kumar, M. Mazumder, M. Quraishi","doi":"10.5772/INTECHOPEN.74989","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.74989","url":null,"abstract":"Development of non-toxic and environmental friendly corrosion inhibitors is highly desirable owing to the increasing demands of “green chemistry” throughout the world. In view of these several forms of green corrosion inhibitors such as drugs or medicines, plant extracts, ionic liquids and synthetic inhibitors derived from multicomponent reactions (MCRs) and mechanochemical mixing are being employed. Nowadays, MCRs in association with microwave and ultrasound irradiations represent one of the best green strategies. Natural polysaccharides particularly chitosan derivatives gained substantial advancement. Chitosan and its several derivatives have been employed effective as corrosion inhibitors for metals and alloys in various aggressive media. The present chapter features the collection of major works that have been published on the inhibition effect of chitosan and its derivatives. The utilization of the chitosan and its derivatives as effective corrosion inhibitors is based on the fact that they contain several polar functional groups such as amino (-NH2), hydroxyl (-OH) and acetyl (-COCH3) groups that effectively bind with metallic surface and behave as adsorption centers.","PeriodicalId":170888,"journal":{"name":"Chitin-Chitosan - Myriad Functionalities in Science and Technology","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132774297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Gutiérrez-Martínez, Aide Ledezma-Morales, Luz del Carmen Romero-Islas, A. Ramos-Guerrero, J. Romero-Islas, C. Rodríguez-Pereida, P. Casas-Junco, L. Coronado-Partida, R. González-Estrada
{"title":"Antifungal Activity of Chitosan against Postharvest Fungi of Tropical and Subtropical Fruits","authors":"P. Gutiérrez-Martínez, Aide Ledezma-Morales, Luz del Carmen Romero-Islas, A. Ramos-Guerrero, J. Romero-Islas, C. Rodríguez-Pereida, P. Casas-Junco, L. Coronado-Partida, R. González-Estrada","doi":"10.5772/INTECHOPEN.76095","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.76095","url":null,"abstract":"In the present chapter, results about the efficacy of chitosan (Chi) on sporulation, myce - lial growth, germination, as well as quality parameters on fruits are shown. The results demonstrate that chitosan can control various phytopathogen isolates from diverse fruits. The pathogens in the genera Colletotrichum , Fusarium , and Rhizopus are involved in important postharvest disease losses throughout the world. In Nayarit, producers had reported high postharvest losses not only at field but also during the commercial chain with their products, besides the resistance of several pathogens to fungicides, which traditionally are applied for controlling diseases. In this sense, the aim of this research group is focused on the research of alternative and effective methods for controlling post - harvest diseases. In vivo results are promising due to a good control in important tropical fruits like banana, avocado, mango, and jackfruit. An enhancement in the chitosan anti - microbial activity is reported with the combination with GRAS substances, as well as the use of nanotechnology. Chitosan can be an environment-friendly alternative to the use of chemical fungicides for controlling postharvest diseases in fruits.","PeriodicalId":170888,"journal":{"name":"Chitin-Chitosan - Myriad Functionalities in Science and Technology","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134433042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chitosan’s Wide Profile from Fibre to Fabrics: An Overview","authors":"Xue Luo, Li Li","doi":"10.5772/INTECHOPEN.76196","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.76196","url":null,"abstract":"","PeriodicalId":170888,"journal":{"name":"Chitin-Chitosan - Myriad Functionalities in Science and Technology","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125188860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Introductory Chapter: Multitask Portfolio of Chitin/Chitosan: Biomatrix to Quantum Dot","authors":"R. Dongre","doi":"10.5772/INTECHOPEN.77218","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.77218","url":null,"abstract":"Rational designing of novel materials has addressed diverse technical needs and industrial problems in addition to their own sizeable share in the prosperity of modern sciences. Biomolecule/polymer yields from natural sources like fungi, bacteria, animals and plants is fascinating due to the innate endurance of the environment and life [1]. Hence, scientists have searched many natural polysaccharides and biopolymers, including agar, algin, carrageenan, glycogen, glycan, pectin and chitin, because of their embryonic/innovative potential to cater for futuristic demands in science and technology (S&T) [1, 2].","PeriodicalId":170888,"journal":{"name":"Chitin-Chitosan - Myriad Functionalities in Science and Technology","volume":"500 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123058558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marilyn Porras-Gómez, J. Vega-baudrit, S. Núñez-Corrales
{"title":"Ampicillin-Loaded Chitosan Nanoparticles for In Vitro Antimicrobial Screening on Escherichia coli","authors":"Marilyn Porras-Gómez, J. Vega-baudrit, S. Núñez-Corrales","doi":"10.5772/INTECHOPEN.76034","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.76034","url":null,"abstract":"Purpose: To develop ampicillin-loaded chitosan nanoparticles by modified ionic gelation method for evaluating their antimicrobial activity onto Escherichia coli . Methods: Ampicillin-loaded chitosan nanoparticles (CHT-NPs) prepared by ionic gela - tion method with sodium tripolyphosphate as cross-linking agent. Drug release param eters (zeta potential, particle size, entrapment efficiency, and in vitro drug release) were assessed in relation to CHT-NP antimicrobial profile on E. coli . Antibacterial properties of CHT-NP formulation with ampicillin were found better than mere ampicillin without CHT-NPs. Results: SEM, AFM images revealed dimensions of CHT-NPs with irregularity in shape/ size. Optimized concentrations of chitosan 0.5% w/v with three different ratios (0.05% to 0.3% w/v) of TPP proved optimal for the evaluation of antibacterial profile of CHT-NPs. In vitro ampicillin-loaded CHT-NP delivery studies revealed an initial burst followed by slow sustained drug release, demonstrating superior antimicrobial activity than plain ampicillin, due to the synergistic effect of chitosan and ampicillin . Conclusion: Chitosan content and cross-linking agent concentrations are control factors in synthesis of the optimized CHT-NP formulation. CHT-NPs with ampicillin cargo capa bly sustained ampicillin delivery due to NP size and increased surface charge, resulting in efficient growth inhibition in assays with E. coli .","PeriodicalId":170888,"journal":{"name":"Chitin-Chitosan - Myriad Functionalities in Science and Technology","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133825893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Hernández-Patlán, B. Solís-Cruz, B. Hargis, G. Téllez
{"title":"Chitoneous Materials for Control of Foodborne Pathogens and Mycotoxins in Poultry","authors":"D. Hernández-Patlán, B. Solís-Cruz, B. Hargis, G. Téllez","doi":"10.5772/INTECHOPEN.76041","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.76041","url":null,"abstract":"Public concern with the incidence of antibiotic-resistant bacteria, particularly among foodborne pathogens has been challenging the poultry industry to find alternative means of control. Chitosan is a modified, natural biopolymer derived by deacetylation of chi - tin. The antimicrobial activity and film-forming property of chitosan makes it a poten tial source of food preservative or coating material of natural origin for improvement of quality and shelf life of various foods of agriculture, poultry, beef and seafood origin. In addition to its use as an antimicrobial, it has been shown that it has good proper- ties as a mycotoxin adsorbent. The purposes of the present chapter is to summarize our experience using chitin-chitosan from Deacetylated 95% food grade chitosan (Paragon Specialty Products LLC Rainsville, AL) or Aspergillus oryzae meal (Fermacto ® , PetAg Inc., Hampshire IL) to control foodborne pathogens, improve performance, biological sani - tizer and mycotoxin binder in commercial poultry.","PeriodicalId":170888,"journal":{"name":"Chitin-Chitosan - Myriad Functionalities in Science and Technology","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123858025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Carboxymethyl-Chitosan Cross-Linked 3- Aminopropyltriethoxysilane Membrane for Speciation of Toxic Chromium from Water","authors":"N. Kano","doi":"10.5772/INTECHOPEN.76035","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.76035","url":null,"abstract":"Adsorption of Cr(VI) from aqueous solution onto the nanomaterials prepared by modified chitosan was investigated in a batch system to evaluate the efficiency of biomass as an adsorbent. The crosslinking materials of chitosan & silicon dioxide and carboxymethyl chitosan & silicon dioxide were synthesized, respectively, as new adsorbent materials for the removal of Cr(VI) from aqueous solutions. The adsorption potential of Cr(VI) by the nanomaterials for desalination was investigated by varying experimental conditions such as pH, contact time and the dosage of the nanomaterials. Adsorption isotherms of Cr(VI) onto the membrane were studied with varying initial concentrations under optimum experiment conditions. The surface property of the membrane was characterized by SEM (scanning electron microscope) and Fourier transform infrared spectrometer (FT-IR). The concentrations of Cr(VI) in solution are determined by ICP-AES (inductively coupled plasma atomic emission spectrometry). The membrane of carboxymethyl chitosan & silicon dioxide exhibited higher adsorption capacity than the membrane of chitosan & silicon dioxide for Cr(VI). The adsorption sites and specific surface area may be increased by changing from chitosan to carboxymethyl chitosan. The maximum adsorption capacity was estimated as 80.7 mg (cid:1) g (cid:3) 1 for Cr(VI) under the optimum conditions.","PeriodicalId":170888,"journal":{"name":"Chitin-Chitosan - Myriad Functionalities in Science and Technology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122031459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chitin/Chitosan’s Bio-Fertilizer: Usage in Vegetative Growth of Wheat and Potato Crops","authors":"Boukhlifi Fatima, M. Zahrae, R. Razouk","doi":"10.5772/INTECHOPEN.75208","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.75208","url":null,"abstract":"This chapter consists of valuing the chitosan to create bio-fertilizers as fertilizers without going through the composting process because of their richness in the nutrient base elements of plants: nitrogen and phosphorus. Physicochemical analyses of the chitosan focused on pH, dry matter, organic matter, nitrogen, phosphorus and potassium as well as IR and XRD. The samples thus prepared were monitored for 15 days. PH, temperature and conductivity were monitored daily. According to the physicochemical analyses of waste (nitrogen, phosphorus and potassium) and the nutritional needs of our selected crop (soft wheat, Arrehane variety which are 90-90-50 U/ha), several doses are then determined for the purpose of the optimal formula after their application on the crop. An application of bio-fertilizer on the potato was also undertaken. Follow-ups were carried out during this study, such as the monitoring of the vegetative growth of wheat and the mineralization of the soil via its physicochemical analyses. The results show that our bio-fertilizer is rich in nitrogen with 4.98% and phosphorus with 1.42% and mineralizes quickly on the ground while leaving the soft wheat to absorb its nutrients effectively and improving its growth properties, then giving good yields.","PeriodicalId":170888,"journal":{"name":"Chitin-Chitosan - Myriad Functionalities in Science and Technology","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130811560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}