Overview of Electrospinned Chitosan Nanofiber Composites for Wound Dressings

Abstract

Chitosan has a medical application because of its natural origin and properties of bio- degradability, biocompatibility, nontoxicity, and antimicrobial capacity. Electrospinning produces non-woven nanofibers to wound dressing with high specific surface area and small pores. These properties are favorable for absorption of exudates and prevent the penetration of bacteria, thus promoting wound healing. For this reason, chitosan blends are used to produce nanofiber dressings, and the characterization of the structural, mechanical, and biological properties is very promising for further studies. Nowadays, the researchers are seeking for biomaterials that provide modern dressings with many qualities, which are designed to promote wound healing. In this chapter, the electrospin- ning parameters that affect the nanofiber properties based on chitosan to prepare wound dressings are highlighted.