D. M. Marturello, K. B. de Sousa, B. L. Boger, S. A. Shull, K. L. Perry
{"title":"Evaluation of a pressure-sensitive treadmill in normal cats","authors":"D. M. Marturello, K. B. de Sousa, B. L. Boger, S. A. Shull, K. L. Perry","doi":"10.1111/jsap.70131","DOIUrl":"10.1111/jsap.70131","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate a pressure-sensitive treadmill in normal cats to determine feasibility as a tool for kinetic gait assessment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Institutional ethical approval was obtained. Cats with no evidence of orthopaedic disease were prospectively enrolled and acclimatised to the pressure-sensitive treadmill. Cats were gaited until three valid trials of 10 gait cycles each were obtained. After normalising to % body weight, peak vertical force, vertical impulse, symmetry index, step phase duration, step length and time for data collection were reported.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Fifty cats with body weights of 4.9 ± 1.1 kg met inclusion criteria. Forelimb peak vertical force and vertical impulse were 57.5 ± 4.2 N and 27.2 ± 3.4 Ns, respectively. Hindlimb peak vertical force and vertical impulse were 46.4 ± 3.8 N and 21 ± 3.1 Ns, respectively. Forelimb and hindlimb symmetry index were 0.99 ± 0.04% and 1.01 ± 0.07%, respectively. Step phase duration was 65.2 ± 3.6% in the forelimbs and 61.2 ± 2.7% in the hindlimbs, while step length was 21.9 ± 2.4 cm and 22.0 ± 2.3 cm in the forelimbs and hindlimbs, respectively. Data collection time was 3.5 ± 1.5 minutes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>The pressure-sensitive treadmill produced consistent and repeatable kinetic data, was easy and fast to use, and cats readily participated in most cases. The homogeneity of protocols using pressure-sensitive treadmill could allow for useful gait comparisons between studies, facilities and patients in future investigations. This is particularly important in feline literature where case numbers at individual facilities are typically small.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 9","pages":"792-797"},"PeriodicalIF":1.5,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.70131","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147616274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Allerton, M. J. Whittle, L. Durkin, C. Prior, M. Trehy, H. Swales, F. Duplan, S. Borgonovi, G. Pinchbeck, I. Gajanayake, M. Dunning, T. Sparks, P. Watson, G. C. A. Amos, K. McCallum, J. Bazelle, A. Kent
{"title":"Clinical benefit of faecal microbiota transplantation administered via a single retention enema as an adjunctive treatment in dogs with chronic enteropathy: a randomised controlled trial","authors":"F. Allerton, M. J. Whittle, L. Durkin, C. Prior, M. Trehy, H. Swales, F. Duplan, S. Borgonovi, G. Pinchbeck, I. Gajanayake, M. Dunning, T. Sparks, P. Watson, G. C. A. Amos, K. McCallum, J. Bazelle, A. Kent","doi":"10.1111/jsap.70137","DOIUrl":"10.1111/jsap.70137","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate the clinical benefit of faecal microbiota transplantation administered <i>via</i> a single retention enema, as an adjunctive treatment in the management of dogs with chronic enteropathy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Blinded, randomised controlled trial. Dogs with chronic enteropathy (>3 weeks of small or mixed intestinal diarrhoea) were randomly allocated to either the faecal microbiota transplantation or standard treatment group (ratio 1:1) <i>via</i> blinded selection. Dogs in the standard treatment group had a diet change only, while dogs in the faecal microbiota transplantation group had a diet change and faecal microbiota transplantation. faecal microbiota transplantation was performed using fresh faecal material from donor dogs, screened for selected enteropathogens and administered <i>via</i> retention rectal enema. Outcomes measured included the Canine Inflammatory Bowel Disease Activity Index, faecal score and the owner's reported improvement. Group comparisons were made using Fisher's exact tests (owner-reported outcomes) and Kruskal–Wallis tests adjusted for ties (Canine Inflammatory Bowel Disease Activity Index and faecal score).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Forty-two dogs with chronic enteropathy (median Canine Inflammatory Bowel Disease Activity Index score 6 [range 4 to 11]) were included in the study. Twenty-five dogs were randomly assigned to receive faecal microbiota transplantation, while 17 dogs were allocated to standard treatment. A progressive improvement in stool consistency (reduced faecal score) was recorded over time for most dogs in both groups. By Day 90, the rates of owner-defined clinical improvement were 76% (CI 54% to 90%) in the faecal microbiota transplantation group and 73% (CI 40% to 92%) in the standard treatment group. No significant differences were evident between the two groups based on the proportion of owners that reported clinical improvement, Canine Inflammatory Bowel Disease Activity Index score or faecal score.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>This study did not demonstrate a clear clinical benefit for adjunctive faecal microbiota transplantation <i>via</i> single retention enema in dogs with chronic enteropathy compared to diet change alone, although the small sample size means that a type II error cannot be excluded. The similar outcome for both groups supports high rates of food responsiveness among this cohort of chronic enteropathy dogs.</p>\u0000 </section>\u0000 </","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 9","pages":"798-809"},"PeriodicalIF":1.5,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.70137","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147717213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toddlers and terriers: a One Health partnership to combat antimicrobial resistance","authors":"M. Prodanuk, F. Emdin","doi":"10.1111/jsap.70136","DOIUrl":"10.1111/jsap.70136","url":null,"abstract":"<p>“Do you want to provide a free consult?” I ask Michael as I slide into the wobbly metal chair and kick my flattened gym bag under the table. The pita shop is crowded as always, and the table rocks slightly every time either of us touches it.</p><p>He raises an eyebrow. “Depends. Do I get paid in garlic sauce?”</p><p>“That's above my pay grade”, I say, pushing damp hair out of my face.</p><p>Our weekly post-workout pita lunch has become our ritual over the past year. We met in graduate school and are both studying clinical epidemiology. I'm a shelter medicine veterinarian patching up neglected dogs and anxious cats and Michael is a paediatric infectious diseases physician. Despite different clinical backgrounds, our “One Health” friendship blossomed over a shared interest in antimicrobial resistance (AMR) in humans and animals. As it turned out, Michael's patients were struggling with the same antibiotic-resistant “super bugs” as my furry friends.</p><p>“Of course”, he tells me, grinning across the table. He cracks his pop with a hiss of escaping air, “What's up in the world of puppies and kittens?”</p><p>“I have a middle-aged terrier mix with its third urinary tract infection (UTI) in three months. The owners finally agreed to a urine culture”.</p><p>I scroll through my phone until I find the results and rotate the screen towards him. “It grew <i>E. coli</i>, resistant to most antibiotics; looks like an extended-spectrum beta-lactamase (ESBL)-producer”. I tell him, “And before you ask”, I cut him off with a gentle wave of the hand, “No obvious underlying reason for the frequent UTIs. No stones on ultrasound, diabetes or other risk factors”. I continue, “I haven't seen this dog before, but her regular vet prescribed cephalexin for 14 days a couple of times. Sadly, resistant to that now too, so I'm going to prescribe a third-generation cephalosporin called cefovecin”.</p><p>“I haven't heard of that antibiotic before”, Michael quips, “You vets get all the new fancy drugs! Those previous 14-day courses sound long, though, and I worry they may have contributed to resistance”.</p><p>“Agreed”, I continue, “and that's why I'm debating the optimal duration. Since this is a recurrent case, should I stick with the standard three to five days (Weese et al., <span>2019</span>)? Or go longer?”</p><p>Michael ponders, “Well, I'm no expert in terriers, but in teens and adults, three days is often enough for uncomplicated UTIs (Nelson et al., <span>2024</span>), even when they've had UTIs before. We usually reserve longer durations for younger children and infections that have ascended to the kidneys”.</p><p>He pauses, scratching his head: “You know, your terrier reminds me of this little girl, a toddler, that I follow in clinic for frequent UTIs. Her doctor was prescribing longer and longer courses of antibiotics, but the infections kept coming back. She even had to be hospitalised for intravenous antibiotics once, since the bacteria were resistant to all oral","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 9","pages":"755-757"},"PeriodicalIF":1.5,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.70136","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147674495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Paterson, C. McKenna, G. Kadler, M. Arsenault, G. Mallet, A. Chan, V. Sammut, G. Leblond, S. Lim, M. Cortez, F. James
{"title":"Generalised absence seizures in Cavalier King Charles Spaniels presenting with paroxysms: eight cases (2016-2025)","authors":"R. Paterson, C. McKenna, G. Kadler, M. Arsenault, G. Mallet, A. Chan, V. Sammut, G. Leblond, S. Lim, M. Cortez, F. James","doi":"10.1111/jsap.70141","DOIUrl":"10.1111/jsap.70141","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To describe the clinical and electroencephalographic findings associated with absence seizures in a population of Cavalier King Charles Spaniels.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>This was a retrospective descriptive case series of Cavalier King Charles Spaniels diagnosed with absence seizures at two veterinary referral hospitals between 2016 and 2025, whereby at least one ambulatory video-electroencephalography study was available.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Data from eight dogs were included for review. The mean video-electroencephalography study duration was 373 minutes (range 7 to 1783). All dogs showed ictal discharges characterised by generalised onset, 3 to 4 Hz, spike-and-wave complexes with a caudal midline dominance, consistent with the current electrographic definitions of absence seizures in human medicine. Ictal discharges were time-locked to myoclonus (5/8, 62.5%), behavioural arrest (3/8, 37.5%) or of ≥10 seconds without motor manifestations (4/8, 50.0%). Following treatment with anti-seizure medication, a reduction in paroxysm frequency by ≥50% was reported by caregivers of 5/6 (83.3%) dogs, with 4/4 (100%) demonstrating improved ictal discharge severity on follow-up video-electroencephalography. One dog was hospitalised due to poor absence seizure control and ultimately euthanased despite inpatient treatments. Although fly catching was a primary complaint in two dogs, it was only captured in one, being time-locked to beta-background activity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>This is the first case series reporting generalised absence seizures as an electroclinical syndrome in Cavalier King Charles Spaniels that is consistent with the current electrographic definition of absence seizures in human medicine.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 9","pages":"822-829"},"PeriodicalIF":1.5,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.70141","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147973422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Costa, K. Perry, D. Low, P. L. de la Oliva, M. Karlin, K. Barnes, C. E. Baker, S. Rutherford
{"title":"Ventral coxofemoral luxation in poodle breeds: multicentre retrospective case series","authors":"L. Costa, K. Perry, D. Low, P. L. de la Oliva, M. Karlin, K. Barnes, C. E. Baker, S. Rutherford","doi":"10.1111/jsap.70130","DOIUrl":"10.1111/jsap.70130","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To investigate whether ventral coxofemoral luxation is more common in poodles and poodle crosses than other breeds, detail the role of trauma in development and retrospectively describe treatment and outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Retrospective cohort study of 25 poodle or poodle crosses with ventral coxofemoral luxation. Records of all dogs sustaining coxofemoral luxation were reviewed, with poodles and poodle crosses suffering ventral coxofemoral luxation being retained for analysis. Data collected: concurrent conditions, degree of trauma, previous hip luxation history, treatment at presentation, complications including incidence of reluxation and treatment thereof.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Coxofemoral luxations were identified in 627 dogs. Of these, 123 were ventral. Fifty-one coxofemoral luxations occurred in poodles or poodle crosses, with 25 being ventral. Poodle and poodle crosses were significantly more likely to experience ventral luxation compared to other breeds (<i>P</i> < .001). Twenty-four cases sustained no major trauma. Initially, non-surgical treatment was performed in 17 cases, surgical treatment in five and no treatment in three. The use of hobbles (<i>P</i> = .554) or their duration (<i>P</i> = .445) was not associated with reluxation risk. Reluxation occurred in seven cases after non-surgical treatment, with five being revised surgically. In total, surgery was performed on 11 occasions: toggle pin (4), femoral head and neck ostectomy (6) and total hip replacement (1).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>Poodles and their crosses were shown to be at an increased risk of ventral coxofemoral luxation compared to all dogs with luxations. There was not a consistently successful management strategy for these cases and owners should be informed accordingly.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 9","pages":"785-791"},"PeriodicalIF":1.5,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147618696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. d. S. Schiavi, C. Y. A. Kawabata, J. V. P. Campos, L. N. Lima, A. M. A. Abranches, L. L. Patente, V. D. Laranjeira, V. Nowosh, J. V. de Assis, A. J. S. de Souza
{"title":"Beyond the stomach: early bone metastases revealing canine gastric adenocarcinoma","authors":"G. d. S. Schiavi, C. Y. A. Kawabata, J. V. P. Campos, L. N. Lima, A. M. A. Abranches, L. L. Patente, V. D. Laranjeira, V. Nowosh, J. V. de Assis, A. J. S. de Souza","doi":"10.1111/jsap.70134","DOIUrl":"10.1111/jsap.70134","url":null,"abstract":"<p>A 9-year-old male shih-tzu dog was admitted with a 4-day history of lameness in the left pelvic limb, with no radiographic abnormalities. Abdominal ultrasonography revealed thickening of the gastric body wall and splenomegaly. The dog showed transient improvement in lameness after anti-inflammatory therapy; however, 2 weeks later, it returned with severe pain and impairment of the left thoracic limb. Repeat radiographic evaluation demonstrated multiple osteolytic lesions (left femur, left ilium, fifth lumbar vertebra and left humerus) (Fig 1A). Fine-needle aspiration cytology of the humerus suggested a malignant round cell neoplasm (Fig 1B). Eighteen days after admission, the animal showed clinical worsening, intense pain, and poor response to analgesic and supportive therapies. Given poor prognosis, euthanasia was elected and necropsy was performed. Grossly, the stomach showed mural thickening of the gastric body and pyloric antrum, forming ulcerated plaque-like lesions (1.0 to 1.5 cm). The splenic parenchyma exhibited irregular white-to-yellow areas. Multifocal bone lysis was observed, and the mesenteric lymph nodes were enlarged. Tissue samples were collected for histopathology (haematoxylin and eosin and Alcian blue [AB]), and immunohistochemistry assessed pan-cytokeratin (AE1/AE3) expression. Microscopically, a poorly demarcated, multifocal infiltrative neoplasm involved all layers of the stomach. The neoplasm exhibited an irregular tubular arrangement of AB-positive polygonal to round cells with frequent signet-ring morphology (Fig 1C). Frequent lymphovascular invasion and 13 mitotic figures in 2.37 mm<sup>2</sup> were observed. Pan-cytokeratin immunostaining confirmed the epithelial origin of the primary mixed-type gastric adenocarcinoma and its metastases in the spleen, lymph nodes, liver and bones (Fig 1D–F).</p><p><b>G. d. S. Schiavi:</b> Investigation; methodology; validation; visualization; writing – review and editing; formal analysis; data curation; writing – original draft. <b>C. Y. A. Kawabata:</b> Investigation; methodology; validation; visualization; writing – review and editing; formal analysis; data curation; writing – original draft. <b>J. V. P. Campos:</b> Investigation; writing – original draft; methodology; visualization; writing – review and editing; formal analysis. <b>L. N. Lima:</b> Investigation; writing – original draft; methodology; visualization; writing – review and editing; formal analysis. <b>A. M. A. Abranches:</b> Investigation; writing – original draft; methodology; visualization; writing – review and editing; formal analysis. <b>L. L. Patente:</b> Investigation; writing – original draft; methodology; visualization; writing – review and editing; formal analysis. <b>V. D. Laranjeira:</b> Investigation; writing – original draft; methodology; visualization; writing – review and editing; formal analysis. <b>V. Nowosh:</b> Investigation; writing – original draft; methodology; formal analysis; validation; visual","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 9","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.70134","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Partial cranial internal hemipelvectomy in a feline patient with ilial osteosarcoma – a case report","authors":"S. Walsh, N. Schneider, N. Bacon","doi":"10.1111/jsap.70135","DOIUrl":"10.1111/jsap.70135","url":null,"abstract":"<p>A 15-year-old male domestic shorthair cat was presented with a mass over the left ilium. Computed tomography showed an osteolytic lesion originating from the left ilial wing with soft tissue invasion but no pulmonary metastasis. Cytology was consistent with a sarcoma, with axial osteosarcoma most likely. A partial cranial internal hemipelvectomy was performed, preserving the left pelvic limb and the caudal sacroiliac joint. Histopathology confirmed a poorly differentiated chondroblastic osteosarcoma with a mitotic count of 61 per 2.37 mm<sup>2</sup>. Surgical margins were clear, with a minimum 9-mm tumour-free margin. The cat recovered well, resumed normal activity by 3 weeks, and had no lameness. Adjuvant carboplatin chemotherapy was administered 20 days postoperatively and was continued for six cycles. Follow-up thoracic radiographs at multiple intervals showed no metastasis, and pelvic radiographs at 6 months revealed no local recurrence or pelvic disruption. At 473 days postsurgery, the cat remained active and disease-free. This case supports partial cranial internal hemipelvectomy as a viable option for feline ilial wing osteosarcoma.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 9","pages":"843-846"},"PeriodicalIF":1.5,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147674530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Miyakawa, M Nakano, M Ishizaka, A Miyagawa, Y Miyagawa, N Takemura
{"title":"Clinical findings and outcomes of juvenile-onset chronic kidney disease of unknown aetiology in dogs: a retrospective study of 36 cases (2010-2023).","authors":"H Miyakawa, M Nakano, M Ishizaka, A Miyagawa, Y Miyagawa, N Takemura","doi":"10.1111/jsap.70187","DOIUrl":"https://doi.org/10.1111/jsap.70187","url":null,"abstract":"<p><strong>Objectives: </strong>To describe the clinical findings and outcomes of juvenile-onset chronic kidney disease of unknown aetiology in dogs.</p><p><strong>Materials and methods: </strong>This retrospective study included 36 client-owned dogs under 3 years of age with chronic kidney disease. In the observational cohort study, the signalment and clinicopathology findings in the dogs (n = 36) were described. A longitudinal analysis (n = 28) was performed to investigate the time to chronic kidney disease progression and death. The risk of chronic kidney disease progression defined as increased >25% of serum creatinine concentration was calculated using the Cox proportional hazard model.</p><p><strong>Results: </strong>The most common breeds were Labrador retrievers and Shetland sheepdogs (n = 5, respectively). Seven dogs were classified as chronic kidney disease stage 1, 17 as stage 2, eight as stage 3 and four as stage 4 according to International Renal Interest Society guidelines. The prevalence of proteinuria (urine protein:creatinine ratio ≥ 0.5) was 35%. None of the dogs had an indirect systolic blood pressure ≥ 160 mmHg. Serum total calcium concentration at presentation was positively associated with the risk for chronic kidney disease progression (hazard ratio, 2.24; 95% confidence interval, 1.11 to 4.53; P = .03). All dogs with chronic kidney disease stage 3 experienced progression to stage 4. Overall, the median survival time (95% confidence interval) was 1461 days (530 to 2620 days).</p><p><strong>Clinical significance: </strong>Juvenile-onset chronic kidney disease of unknown aetiology was diagnosed in the various breeds of dogs. The prevalence of hypertension was lower than reported in previous studies. Serum total calcium concentration at presentation was associated with the risk of chronic kidney disease progression. Our study provides useful information on the characteristics and outcomes of canine juvenile-onset chronic kidney disease.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148880919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Vila Cabaleiro, S Wyatt, H G Miller, E Fitzgerald, G O Bertoldi, C Llanos
{"title":"Non-rim-enhancing intracranial abscess in a cat confirmed by MRI and histopathology.","authors":"A Vila Cabaleiro, S Wyatt, H G Miller, E Fitzgerald, G O Bertoldi, C Llanos","doi":"10.1111/jsap.70193","DOIUrl":"https://doi.org/10.1111/jsap.70193","url":null,"abstract":"","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148865379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epidemiological, clinical and diagnostic aspects of feline otitis: a retrospective study of 103 cases from the dermatology service of a veterinary teaching hospital (2020-2022).","authors":"L Humeau, N Do Dinh, H Dropsy, N Cochet-Faivre","doi":"10.1111/jsap.70186","DOIUrl":"https://doi.org/10.1111/jsap.70186","url":null,"abstract":"<p><strong>Objectives: </strong>To describe the epidemiological characteristics, clinical features, diagnostic findings and underlying causes of feline otitis in cases presented to a French veterinary teaching hospital.</p><p><strong>Materials and methods: </strong>Medical records of cats diagnosed with otitis by the dermatology department of a veterinary teaching hospital between September 2020 and March 2022 were retrospectively reviewed. Signalment, clinical history, video-otoscopic findings, cytology, imaging and histopathology results were collected.</p><p><strong>Results: </strong>A total of 103 cats were diagnosed with otitis. Maine Coon, Sphynx, Turkish Angora and Selkirk Rex cats were significantly overrepresented. Age distribution showed increased case numbers in cats younger than 6 years, with another peak at 12 to 14 years of age. Chronic otitis represented 71.8% of cases. A primary cause was identified in 66.0% of cases, most frequently feline atopic syndrome, inflammatory polyps, neoplasia, isolated otitis media and otoacariasis. Staphylococcus spp. predominated in cultures (84.6%). Suppurative otitis was identified in 42 cats (40.8%). Video-otoscopy demonstrated high sensitivity and specificity for inflammatory polyps and otoacariasis.</p><p><strong>Clinical significance: </strong>Feline otitis was predominantly chronic, with inflammatory polyps most commonly identified in younger cats and neoplasia in older cats; suppurative otitis was frequent and mainly associated with inflammatory polyps, otitis media and neoplasia. These findings emphasise the need for a comprehensive diagnostic approach to feline otitis, incorporating video-otoscopy and advanced imaging to identify age-related primary causes and guide clinical decision-making.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148829562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}