Journal of Small Animal Practice最新文献

{"title":"Long-term clinical outcomes of healthy dogs with increased alanine aminotransferase.","authors":"J Adams","doi":"10.1111/jsap.13777","DOIUrl":"https://doi.org/10.1111/jsap.13777","url":null,"abstract":"<p><strong>Objectives: </strong>To define a reference interval for alanine aminotransferase for the practice laboratory and then identify and longitudinally follow the clinical health and alanine aminotransferase levels in a cohort of clinically healthy dogs with increased alanine aminotransferase levels documented during wellness screening.</p><p><strong>Materials and methods: </strong>Alanine aminotransferase levels of 125 clinically healthy dogs were used to define a reference interval for the practice laboratory. The electronic records of 315 clinically healthy dogs which had undergone wellness screening including assessment of alanine aminotransferase levels at a first-opinion veterinary hospital in the UK were reviewed between January 2012 and January 2023. Clinically healthy dogs with increased alanine aminotransferase levels relative to the top of the reference interval determined for the practice on at least one test during the study period were identified. These were longitudinally followed through electronic medical records to determine their long-term clinical outcomes over a period of up to 11 years.</p><p><strong>Results: </strong>The reference interval for alanine aminotransferase in the practice laboratory was calculated as 10.6 to 181.8 U/L. Nineteen clinically healthy dogs were identified as having increased alanine aminotransferase levels. One dog from the group with increased alanine aminotransferase levels was diagnosed with chronic hepatitis and died of liver failure, while the other 18 dogs died of other causes, or were still alive at the end of the study, with no clinical signs associated with liver disease. One dog in the group with consistently normal alanine aminotransferase levels also died from clinical signs attributed to liver disease.</p><p><strong>Clinical significance: </strong>Only a small proportion of clinically healthy dogs with increased alanine aminotransferase levels documented on wellness screening developed clinically relevant liver dysfunction over long-term follow-up.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142154381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic accuracy of radiographs for the diagnosis of humeral intracondylar fissure in dogs.","authors":"M Sprocatti, M A Solano, V Volckaert, A Danielski","doi":"10.1111/jsap.13784","DOIUrl":"https://doi.org/10.1111/jsap.13784","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the diagnostic accuracy of radiographs in identifying humeral intracondylar fissures in dogs.</p><p><strong>Materials and methods: </strong>Clinical data from dogs undergoing CT and radiographic elbow investigations at a single institution were reviewed. Based on CT diagnosis, radiographs were classified as having fissures and not having fissures. The radiographic images were evaluated by three blinded observers for the presence/absence of a fissure, type (partial or complete), and for secondary signs that could suggest the presence of a fissure in case this was not visible.</p><p><strong>Results: </strong>A total of 81 radiographs (76 elbows) were reviewed. Based on CT findings, 37 elbows had fissures and 44 did not. Radiographic interpretation demonstrated a sensitivity of 47.7% (confidence interval 95%: 0.40 to 0.59) and specificity of 85.6% (confidence interval 95%: 0.72 to 0.93) in correctly identifying humeral intracondylar fissures. The positive predictive value was 75.5% (confidence interval 95%: 0.64 to 0.84) and the negative predictive value was 66.1% (confidence interval 95%: 0.63 to 0.68). Agreement with CT images was <0.4, and interobserver and intraobserver agreements were <0.8. The radiographic orientation and type of fissure did not significantly affect interpretation outcomes.</p><p><strong>Clinical significance: </strong>Radiographic imaging alone is insufficient for reliably diagnosing humeral intracondylar fissures in dogs.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceptions, practices and preferences of veterinarians and veterinary nurses in the UK on consent for cardiopulmonary resuscitation in pets.","authors":"K Gane, T Sparks, E Thomas","doi":"10.1111/jsap.13778","DOIUrl":"https://doi.org/10.1111/jsap.13778","url":null,"abstract":"<p><strong>Objectives: </strong>Cardiopulmonary resuscitation can be a difficult topic to discuss. The barriers surrounding its discussion are well documented in human medicine but have not previously been examined in veterinary medicine. The objectives of this study is to describe the perceptions, practices and preferences of veterinarians and registered veterinary nurses towards discussing cardiopulmonary resuscitation with pet owners.</p><p><strong>Materials and methods: </strong>An online survey was circulated to veterinarians and registered veterinary nurses in the UK. Open and closed questions were used, with multiple choice and free text answer formats, all of which related to the timing and content, participants' preferences and perceived barriers to cardiopulmonary resuscitation discussions.</p><p><strong>Results: </strong>In total, 290 responses met the inclusion criteria. Almost half of participants [140/290 (48%)] worked in first opinion practice. In total, 100 of 290 (34%) participants were \"very likely\" to discuss cardiopulmonary resuscitation preferences on admission. However, 244 of 272 (90%) said they would rather discuss cardiopulmonary resuscitation prospectively than at the time of a critical event. Most respondents [174/290 (60%)] stated that their practice does not include resuscitation preferences on admission consent forms despite 163 of 290 (56%) \"strongly agreeing\" that cardiopulmonary resuscitation preferences should be routinely discussed on admission. Over half [168/290 (58%)] never discussed costs associated with cardiopulmonary resuscitation and 67 of 290 (23%) never discussed likelihood of survival to discharge with the most common reason being \"unaware of survival statistics.\" Barriers to discussion included fear of causing upset, concerns for owner reactions and unrealistic owner expectations.</p><p><strong>Clinical significance: </strong>Veterinary professionals in the UK face multiple challenges when discussing cardiopulmonary resuscitation with pet owners. Whilst communication skills are an increasing area of focus in veterinary education, specific teaching on the topic of cardiopulmonary resuscitation discussion may be beneficial. Pet owner education may also mitigate some of the challenges to conversation.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Placement, management and complications associated with peripheral intravenous catheter use in UK small animal practice.","authors":"E Haskey, V Maund, F Allerton, B Browse, C Heard, C O'Donnell, K Davison, C Hertel, E Booth, S Lawrence, E Dever, L Bowe, H Taylor, K Hall, K Trimble, M Junior, C Fennell, N Stevenson, A Sterritt, E Penn, L Nowell, A Collins, E Jones, C Scudder","doi":"10.1111/jsap.13782","DOIUrl":"https://doi.org/10.1111/jsap.13782","url":null,"abstract":"<p><strong>Objectives: </strong>To describe the techniques for preparation and placement of peripheral intravenous catheters (PIVCs), to describe the complications associated with PIVCs, and to identify factors associated with PIVC complications in small animal practice in the United Kingdom.</p><p><strong>Materials and methods: </strong>A prospective multicentre observational study was undertaken between January 2022 and January 2023. Data collected included patient information, information regarding the placement and maintenance of PIVCs, and PIVC complications, from privately owned cats and dogs presenting to veterinary institutes in the United Kingdom. Patients required a PIVC to be placed as part of their care and the PIVC was anticipated to be in situ for >24 hours to be eligible for PIVC complication analysis.</p><p><strong>Results: </strong>A total of 19 institutes recorded data regarding 382 PIVCs, with 325 (85.1%) placed in dogs and 57 (14.9%) in cats. The most common reasons for placement were to administer intravenous fluid therapy (74.3%) and intravenous medications (71.7%). There were 102 of 382 (26.7%) PIVCs associated with a complication, with limb swelling/suspected phlebitis in 44 of 382 (11.5%) and PIVC dislodgement/patient interference in 30 of 382 (7.9%) PIVCs. Factors associated with increased risk of complication were more than 1 attempt to place the PIVC, a second or subsequent PIVC being placed during hospitalisation, flush frequency different than every 1 to 24 hours, and flush solution with compound sodium lactate.</p><p><strong>Clinical significance: </strong>Veterinary professionals must be vigilant when monitoring a patient with a PIVC in situ, particularly if a PIVC is associated with one of the aforementioned factors of increased likelihood of complication.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful clinical management of canine intestinal lipogranulomatous lymphangitis through exclusive medical and nutritional treatment: four cases (2018-2023).","authors":"M Crisonà, A M Tardo, M Pietra, S Del Magno, N Linta, A Diana, L V Muscatello, G Peccolo, F Del Baldo","doi":"10.1111/jsap.13783","DOIUrl":"https://doi.org/10.1111/jsap.13783","url":null,"abstract":"<p><strong>Objectives: </strong>To describe clinical, ultrasonographic, pathological features and response to medical therapy of four dogs with intestinal lipogranulomatous lymphangitis.</p><p><strong>Methods: </strong>Retrospective review of medical records of dogs with an ultrasonographic evidence of focal or multifocal intestinal wall thickening and a histological diagnosis of lipogranulomatous lymphangitis. Only dogs that did not undergo surgical resection of the lesions were included. The clinical response to medical treatment, consisting of low-fat or hydrolysed diet along with immunosuppressive agents was assessed; clinicopathological and ultrasonographic abnormalities were re-evaluated over time, with a median follow-up period of 16.5 months.</p><p><strong>Results: </strong>Four dogs met the inclusion criteria. The main historical complaints were diarrhoea (three of four dogs), vomiting (three of four dogs) and abdominal pain (two of four dogs). Clinicopathological abnormalities comprised hypoproteinaemia, hypoalbuminaemia and mild/moderate increase in C-reactive protein levels (three of four dogs). Abdominal ultrasound revealed focal (two of four dogs) or multifocal (two of four dogs) intestinal wall thickening involving distal jejunum, ileum and ileocolic junction. Histopathology of full thickness intestinal biopsies revealed granulomatous enteritis and lymphangitis with lymphangiectasia. Nutritional and medical treatment allowed complete clinical remission in all four dogs within a month of therapy. Improvement of ultrasound abnormalities was noted in three of the four dogs over a 3- to 12-month period.</p><p><strong>Clinical significance: </strong>Intestinal lipogranulomatous lymphangitis is a rare form of canine chronic enteropathy characterised by focal or multifocal intestinal lesions due to the presence of transmural intestinal lipogranulomas. This is the first case series describing successful management of intestinal lipogranulomatous lymphangitis through medical treatment alone.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic resonance imaging findings in dogs with steroid-responsive meningitis-arteritis in the UK and their clinical significance: 53 cases (2013-2021).","authors":"B A Jones, P Agthe, E Scarpante, A Crawford, V Black, I Espadas, S Formoso, A R Fraser","doi":"10.1111/jsap.13775","DOIUrl":"https://doi.org/10.1111/jsap.13775","url":null,"abstract":"<p><strong>Objectives: </strong>To describe the MRI findings in a UK referral population of dogs with steroid-responsive meningitis-arteritis and to determine if they were associated with any specific clinical features or outcomes.</p><p><strong>Materials and methods: </strong>We performed a multi-centre retrospective case series of dogs diagnosed with steroid-responsive meningitis-arteritis in the UK that underwent MRI. Blinded consensus review of the MRI studies was performed and the findings described. The presence or absence of specific MRI abnormalities were analysed for significant associations with presenting signs, results of investigations or case outcomes.</p><p><strong>Results: </strong>Fifty-three dogs were included. The most common MRI findings were paravertebral muscle changes (30/53; 56.6%), meningeal contrast enhancement (13/41; 31.7%) and spinal cord parenchymal T2-W hyperintensity (15/53; 28.3%). Haemorrhage was observed in five of 53 (9.4%) cases - three intradural-extramedullary, one intramedullary and one extradural. Following binary logistic regressions, T2-W spinal cord parenchymal hyperintensity had a significant positive association with paresis/paralysis (odds ratio 14.86, 95% confidence interval 1.42 to 154.99) as did haemorrhage (odds ratio 16.12, confidence interval 2.05 to 126.73). Fifty-two (98.1%) dogs survived to discharge. Relapse occurred in nine of 29 (31.0%) dogs with sufficient follow-up, and no MRI finding had a significant relationship with its occurrence.</p><p><strong>Clinical significance: </strong>Magnetic resonance imaging findings for steroid-responsive meningitis-arteritis can be severe and extensive, as can the clinical presentation. The presence of paresis/paralysis should raise concern for haemorrhage, though most dogs still have a good prognosis.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypoalbuminaemia and its association with disease and clinical outcomes in cats.","authors":"K Y M Fong, I L Oikonomidis, D Leong, G Lo, J Heal, G Woods","doi":"10.1111/jsap.13764","DOIUrl":"https://doi.org/10.1111/jsap.13764","url":null,"abstract":"<p><strong>Objectives: </strong>To report the incidence of feline hypoalbuminaemia and characterise the distribution of presenting disease categories and pathoaetiologies of hypoalbuminaemia in cats. The secondary aim was to evaluate the relationship between hypoalbuminaemia and clinical outcomes.</p><p><strong>Materials and methods: </strong>Medical records of cats with hypoalbuminaemia (<28.0 g/L, reference interval: 28.0 to 39.0 g/L) presenting to a veterinary teaching hospital over 5 years were retrospectively reviewed. The severity of hypoalbuminaemia was further stratified into mild (24.0 to 27.9 g/L), moderate (20.0 to 23.9 g/L) and severe (≤19.9 g/L) groups. The median albumin and severity groups were compared between the determined disease categories, pathoaetiologies and clinical outcomes.</p><p><strong>Results: </strong>The incidence of hypoalbuminaemia was 32.7% (533/1632). Gastrointestinal disease was the most common disease category associated with hypoalbuminaemia [154/533 (28.9%)], of which, 49.4% (76/154) of cats had gastrointestinal neoplasia. Neoplastic [159/533 (29.8%)] and inflammatory conditions [158/533 (29.6%)] were common pathoaetiologies noted. Statistically significant differences in the serum albumin between individual disease and pathoaetiological categories were found. Cats with moderate to severe hypoalbuminaemia had a statistically significantly longer hospitalisation period, cost of treatment and increased odds of death (odds ratio 2.4, 95% confidence interval: 1.3 to 4.6 and odds ratio 3.2, 95% confidence interval: 1.5 to 6.6, respectively).</p><p><strong>Clinical significance: </strong>The incidence of feline hypoalbuminaemia in our study surpasses previous canine reports. Our findings support albumin as a negative acute phase protein in cats, with hypoalbuminaemia frequently associated with inflammatory disease. Hypoalbuminaemia also features prominently in cats with gastrointestinal neoplasia, indicating careful appraisal of the presence of protein-losing enteropathy is required in these cases. Finally, albumin is found to be a prognostic indicator in this study.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of respiratory signs in dogs with chronic gastroenteropathy in a referral population in the United Kingdom: 42 cases (2020).","authors":"A Salas García, L Atkinson, T McCann, J Bazelle","doi":"10.1111/jsap.13779","DOIUrl":"https://doi.org/10.1111/jsap.13779","url":null,"abstract":"<p><strong>Objectives: </strong>To determine the prevalence of respiratory signs in a referral population of dogs with chronic gastroenteropathy in the United Kingdom, and to describe the epidemiology and clinical presentation of the affected dogs.</p><p><strong>Materials and methods: </strong>Retrospective review of canine patients diagnosed with chronic gastroenteropathy in a referral centre in the United Kingdom. Data included signalment, gastrointestinal and respiratory signs, blood analysis results and, where present, diagnostic imaging techniques, endoscopy, videofluoroscopic swallow study, bronchoalveolar lavage results and treatment response. To be included, a follow-up of a minimum of 3 months was required. Cases were excluded if there was no minimum diagnostic dataset, the aetiology of the respiratory signs was other than gastrointestinal disease or a non-gastrointestinal systemic disease was the cause of the gastrointestinal signs.</p><p><strong>Results: </strong>One hundred and forty-eight dogs were included and 42 (28.4%) had concurrent respiratory signs. Gagging (69%) and vomiting (52.4%) were the most common gastrointestinal signs, while coughing (50%), tachypnoea (33.3%) and reverse sneezing (30.9%) were the most common respiratory signs. Abdominal ultrasound was performed in 31 (73.8%) while CT scan was the most common modality for thoracic (62.5%) and head (21.9%) imaging. Endoscopic procedures included gastrointestinal (54.8%), bronchoscopy (19%) and rhinoscopy (23.8%). Dietary modification was the most common treatment (66.67%). Eleven dogs (26.2%) had a relapse of the respiratory signs during the follow-up period, of which, nine (81.8%) had a concurrent relapse of the gastrointestinal signs.</p><p><strong>Clinical significance: </strong>Concurrent respiratory signs in dogs with chronic gastroenteropathy are frequent. A clinical improvement of these respiratory signs might be achieved during the therapeutic management of gastrointestinal disorders.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142120130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcalvarial extension of an intracranial meningioma without obvious interruption of the intervening bone in a dog.","authors":"N Sekiguchi, C Ishikawa, D Ito","doi":"10.1111/jsap.13780","DOIUrl":"https://doi.org/10.1111/jsap.13780","url":null,"abstract":"","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histologic findings of gastrointestinal biopsies and clinical outcome in dogs undergoing cholecystectomy for gallbladder mucoceles: 71 cases (2014-2021).","authors":"M Gondolfe, E C Hans","doi":"10.1111/jsap.13781","DOIUrl":"https://doi.org/10.1111/jsap.13781","url":null,"abstract":"<p><strong>Objectives: </strong>To determine the presence and categorise the severity of enteritis in dogs with gallbladder mucoceles, and evaluate for any associations with enteritis. This study also aimed to report clinical outcome following cholecystectomy and evaluate for associations with survival.</p><p><strong>Materials and methods: </strong>Medical records were retrospectively reviewed (2014 to 2021) for dogs undergoing cholecystectomy and duodenal biopsy procedures for gallbladder mucocele. Signalment, bloodwork, abdominal ultrasound findings, surgical details, histology results and outcomes were reported. Surgeries were considered elective or emergent based on each dog's clinical presentation. Enteritis was categorised based on cell type and severity. Inflammation and clinical outcome were statistically evaluated.</p><p><strong>Results: </strong>Seventy-one dogs met the study criteria. Enteritis was present in 85.9% (61/71) of cases with the majority being lymphoplasmacytic (53.5%). Twelve dogs (16.9%) underwent gastrointestinal biopsies from multiple sites, which revealed the same enteritis type at each location. A total of 87.3% (n = 62) dogs survived, including 90.4% elective and 86% emergent cases. No significant differences in enteritis severity or patient survival were found between elective and emergent cases. Septic peritonitis was diagnosed in two dogs (2.82%). Mortality was significantly associated with leukocytosis, with nonsurviving dogs having a mean WBC count of 27.6 G/L (95% confidence interval: 10.6 to 21.5).</p><p><strong>Clinical significance: </strong>Enteritis is present in a majority of dogs with gallbladder mucocele, especially mild to moderate with lymphoplasmacytic cell type. Obtaining a duodenal biopsy had minimal impact on patient outcome. Compared to previous studies, improved survival in emergent cases was noted. Further studies with long-term follow-up are needed to determine if enteropathy-related signs persist after cholecystectomy.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142120129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}