Journal of Small Animal Practice最新文献

{"title":"Retrospective evaluation of outcomes in dogs with non-associative immune-mediated haemolytic anaemia treated with rivaroxaban as a sole or adjunctive thromboprophylaxis agent: 34 cases (2018-2024).","authors":"S Conway, L Jenkins, J Reeve","doi":"10.1111/jsap.70202","DOIUrl":"https://doi.org/10.1111/jsap.70202","url":null,"abstract":"<p><strong>Objectives: </strong>To describe clinical outcomes, thromboembolic and haemorrhagic complications, and treatment characteristics in dogs with non-associative immune-mediated haemolytic anaemia treated with rivaroxaban at a UK referral hospital.</p><p><strong>Materials and methods: </strong>Retrospective descriptive study of dogs diagnosed with non-associative immune-mediated haemolytic anaemia and prescribed rivaroxaban as part of their management protocol between January 2018 and July 2024.</p><p><strong>Results: </strong>Thirty-four dogs met inclusion criteria. Median admission haematocrit was 14.1% (range 7.0% to 25.5%). Primary management of immune-mediated haemolytic anaemia was with corticosteroids (34/34; 100%), which were the sole agent in 8/34 (24%). Adjunctive therapies included mycophenolate mofetil (26/34; 70.6%), azathioprine (1/34; 2.9%) and leflunomide (1/34; 2.9%). Rivaroxaban was administered at a median total daily dose of 1.2 mg/kg/day (range 1.03 to 1.97 mg/kg/day); 29/34 dogs (85.3%) received concurrent clopidogrel. Confirmed or suspected thromboembolic events occurred in 7/34 dogs (20.6%), all during initial hospitalisation. Gastrointestinal bleeding occurred in 5/34 dogs (14.7%); all five were receiving concurrent corticosteroids, mycophenolate mofetil and rivaroxaban. Two bleeding events were classified as major adverse events, including one fatal case. Overall, 26 dogs (76.5%) survived to discharge. Remission was confirmed in 19/26 discharged dogs (73.1%) at a median of 33 days (range 15 to 156). Relapse occurred in 2/19 dogs (10.5%) post-remission. Of 21 dogs with follow-up available, 20 (95.2%) were alive at last known contact.</p><p><strong>Clinical significance: </strong>This represents one of the largest UK-based cohorts of dogs with non-associative immune-mediated haemolytic anaemia treated with rivaroxaban, demonstrating acceptable survival and remission rates with this thromboprophylaxis protocol. The occurrence of clinically significant gastrointestinal bleeding exclusively in dogs receiving concurrent corticosteroids, mycophenolate mofetil and rivaroxaban represents an important safety signal that warrants consideration and further study.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148982967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful use of insect-based (Hermetia illucens) diet in dogs with food-responsive enteropathy.","authors":"K Murtagh, E Stavroulaki, M Carvalho, E J O'Neill, C T Mooney","doi":"10.1111/jsap.70195","DOIUrl":"https://doi.org/10.1111/jsap.70195","url":null,"abstract":"<p><strong>Objective: </strong>Diet is an integral component of the management of chronic enteropathy in dogs. The role of insect-based diets in this disease remains unknown. The objective of this study was to evaluate the impact of an insect-based (Hermetia illucens) diet in dogs with presumed food-responsive enteropathy.</p><p><strong>Methods: </strong>Twenty-seven client-owned dogs with evidence of chronic enteropathy, in which diet was required as sole management, were enrolled onto this prospective, uncontrolled diet trial. Canine inflammatory bowel disease activity index, faecal score, body condition score and body weight (kg) were recorded pre-enrolment (T₀). Dogs were exclusively fed insect diet and reassessed at 14 (T₁), 30 (T₂) and 90 (T₃) days. Dogs remained in the study if responding and exited the study at various times for additional investigations or alternative treatment(s) if not responding. Comparisons were made within responders over time and between responders and non-responders at T₀. Data are expressed as median (range).</p><p><strong>Results: </strong>Twenty-seven dogs were recruited; seven cases were withdrawn, leaving 20 dogs for analysis. Fourteen/20 dogs (70%) were classified as responders with a decrease in median faecal score from 6.25 (5 to 7) at T₀ to 2 (2 to 5) at T₁ and a median decrease in canine inflammatory bowel disease activity index from 8 (5 to 14) at T₀ to 1 (0 to 5) at T₁. All responders had adequate control at day 90 (T₃), with a median faecal score of 2 (2 to 5) and a median canine inflammatory bowel disease activity index of 0 (0 to 3).</p><p><strong>Clinical significance: </strong>Insect diet improved clinical signs in 70% of chronic enteropathy dogs and could represent another dietary option in the management of this disease.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148963404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of clinically significant bleeding in dogs with severe thrombocytopenia: 159 cases (2012-2021).","authors":"G Smith, E D Bennet, A E Ridyard","doi":"10.1111/jsap.70197","DOIUrl":"https://doi.org/10.1111/jsap.70197","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate risk factors for clinically significant bleeding in dogs with severe thrombocytopenia and to assess whether predictors of bleeding differ between immune thrombocytopenia and other causes, and whether platelet mass is more predictive than platelet count.</p><p><strong>Materials and methods: </strong>Medical records of dogs presenting to a referral institution between 2012 and 2021 with severe thrombocytopenia (platelet count <50 × 10⁹/L) were retrospectively reviewed. Dogs were classified by underlying cause and presence of clinically significant bleeding. Univariable and multivariable logistic regression analyses were performed.</p><p><strong>Results: </strong>A total of 159 dogs were included, of which 74 developed clinically significant bleeding. Eighty-four dogs were classified as having immune thrombocytopenia. Dogs with clinically significant bleeding had lower platelet counts and plateletcrit, and higher leucocyte and monocyte counts. On univariable analysis, immune thrombocytopenia was associated with increased odds of bleeding (odds ratio 3.49, 95% confidence interval 1.83 to 6.85). In the final multivariable model, increasing platelet count was associated with reduced odds of bleeding (odds ratio 0.72 per 10 × 10⁹/L increase, 95% confidence interval 0.55 to 0.95), while increasing monocyte count was associated with increased odds (odds ratio 1.09 per 0.1 × 10⁹/L increase, 95% confidence interval 1.05 to 1.13). Plateletcrit was not independently associated with bleeding. Within the immune thrombocytopenia subgroup, platelet count was not associated with bleeding, whereas monocyte count remained independently associated.</p><p><strong>Clinical significance: </strong>When considering all dogs with severe thrombocytopenia, the lower the platelet count the more likely the dogs are to develop clinically significant bleeding. However, for dogs with immune thrombocytopenia, the relationship between platelet count and the development of clinically significant bleeding is not clear-cut, suggesting that factors beyond platelet number contribute to bleeding risk in this cohort of thrombocytopenic dogs.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148963453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased serum amyloid A and urinary kidney injury marker-1 concentrations in cats with pyelonephritis: a diagnostic accuracy study","authors":"L. R. Jessen,&nbsp;F. S. Moberg,&nbsp;R. Langhorn,&nbsp;A. S. Gravgaard,&nbsp;N. Dupont,&nbsp;N. Bak-Jacobsen,&nbsp;B. J. Reezigt,&nbsp;A. L. Jensen,&nbsp;D. Bienzle,&nbsp;L. N. Nielsen","doi":"10.1111/jsap.70140","DOIUrl":"10.1111/jsap.70140","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To investigate the discriminatory potential of serum amyloid A, neutrophil:lymphocyte ratio, monocyte:lymphocyte ratio and assess renal tubular injury in cats with pyelonephritis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Diagnostic accuracy study using samples from prospectively enrolled cats and stored material. Cats were classified according to diagnosis as pyelonephritis, ureteral obstruction, chronic kidney disease, subclinical bacteriuria, cystitis, or healthy. Serum amyloid A, neutrophil:lymphocyte ratio, monocyte:lymphocyte ratio and urinary kidney injury marker-1 were compared across groups. Receiver operating characteristic curve analysis assessed the performance of inflammatory biomarkers. Serum amyloid A and urinary kidney injury marker-1 were measured consecutively in a subset of cats with pyelonephritis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Samples from 71 cats (pyelonephritis <i>n</i> = 22, other urological conditions <i>n</i> = 35, healthy <i>n</i> = 14) were included. Median serum amyloid A concentration was significantly higher in cats with pyelonephritis, overlapping minimally with other groups. At a threshold of 49.1 mg/L, serum amyloid A showed a positive likelihood ratio of 32, sensitivity of 0.95 (95% CI: 0.74 to 0.99) and specificity of 0.97 (95% CI: 0.85 to 0.99), outperforming neutrophil:lymphocyte ratio. Serum amyloid A normalised in 12/14 cats post-treatment. Urinary kidney injury marker-1 was elevated in more than 50% of cats with pyelonephritis and ureteral obstruction, significantly higher than in healthy cats and those with subclinical bacteriuria or cystitis. Variation in urinary kidney injury marker-1 was observed during follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>At a threshold of 49 mg/L, serum amyloid A is a highly accurate biomarker for differentiating pyelonephritis from other urological conditions. Elevated urinary kidney injury marker-1 suggests frequent proximal tubular injury.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>Pyelonephritis is challenging to diagnose. Serum amyloid A can improve diagnostic precision and support timely treatment decisions. Urinary kidney injury marker-1 helps identify tubular injury; however, the clinical implications remain to be investigated.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 9","pages":"810-821"},"PeriodicalIF":1.5,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.70140","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148015900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haemorrhagic myelopathy causing acute post-operative paralysis in a rabbit (Oryctolagus cuniculus) with a congenital lordosis","authors":"L. A. Bergeron,&nbsp;C. Giron,&nbsp;C. Rosa-Teijeiro,&nbsp;P. Hélie,&nbsp;J. Parent,&nbsp;C. Vergneau-Grosset","doi":"10.1111/jsap.70139","DOIUrl":"10.1111/jsap.70139","url":null,"abstract":"<p>A 7-month-old mixed-breed lionhead entire female rabbit, presented for ovariohysterectomy, displayed a mild bilateral hind limb paresis with external rotation of the hip joints, associated with grade 1/5 pododermatitis of the hind limbs. Investigations were declined by the owner prior to surgery. After a seemingly uncomplicated ovariohysterectomy, the rabbit displayed an acute rapidly progressive bilateral hind limb paralysis with retention of nociception and mild right forelimb paresis. A recheck complete neurologic examination on the following day showed paralysis of the hind limbs without nociception. Post-operative vertebral column radiographs under sedation revealed thoracic lordosis, presumably congenital. Differential diagnoses for paralysis included vascular disease, alteration of the site of congenital vertebral anomaly by perioperative manipulations or iatrogenic medullary injection. Due to the presumed poor prognosis associated with the severity of clinical signs, humane euthanasia was elected. <i>Post mortem</i> magnetic resonance imaging and histopathological examination revealed extensive acute thoracolumbar haemorrhagic myelopathy. Using a comparative medicine approach, a similar complication is reported in children with thoracolumbar vertebral malformation and in horses after general anaesthesia in dorsal recumbency. To the authors' knowledge, this is the first report of non-experimental haemorrhagic myelopathy in a rabbit. Veterinarians should consider this potential complication in rabbits presenting with thoracolumbar lordosis.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 9","pages":"847-853"},"PeriodicalIF":1.5,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation for radiographic changes in the coxofemoral joint and proximal femur following intramedullary stabilisation of diaphyseal femoral fractures using angle-stable interlocking nails in skeletally immature patients","authors":"L. M. Meneghetti,&nbsp;S. R. O'Neill,&nbsp;K. L. Perry","doi":"10.1111/jsap.70129","DOIUrl":"10.1111/jsap.70129","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate a juvenile dog population that sustained diaphyseal femoral fractures surgically stabilised with an angle-stable interlocking nail and evaluate for evidence of proximal femoral malformation both periooperatively and at skeletal maturity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Retrospective study of ten skeletally immature dogs sustaining diaphyseal femoral fractures stabilised using an angle-stable interlocking nail between January 2010 and June 2023. Standardised orthopaedic examination, Canine Brief Pain Inventory and radiographic review were performed at skeletal maturity. Radiographic review included subjective assessment for proximal femoral malformation and objective assessment of anatomic and mechanical angles of alignment in both the frontal and sagittal planes, immediately post-operatively, perioperatively and at long-term follow-up. A Wilcoxon signed rank test was used to assess femoral measurements using the unaffected femur as a control in each dog.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Six of the nine dogs scored 0 on the Canine Brief Pain Inventory, while the remaining three had low scores (maximum of 10/100). No case had evidence of proximal femoral malformation during perioperative follow-up. Two dogs developed bilateral coxofemoral joint osteoarthritis at skeletal maturity. CORONA1 was the only significantly different measurement when comparing the surgical to the unaffected femur at skeletal maturity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>Use of an angle-stable interlocking nail to stabilise femoral diaphyseal fractures in skeletally immature dogs can be performed without significant risk of developing proximal femoral malformation. Reductions in CORONA1 values may be anticipated due to reducing natural femoral procurvatum. Angle-stable interlocking nails should not be considered contraindicated for use in canine juvenile diaphyseal femoral fracture repair.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 9","pages":"774-784"},"PeriodicalIF":1.5,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.70129","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147574640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time-dependent laryngeal desensitisation following topical lidocaine and prilocaine application in cats: a randomised controlled study","authors":"A. Gölgeli Bedir,&nbsp;L. E. Yanmaz,&nbsp;Y. Akçora,&nbsp;Ç. Özkalıpçı,&nbsp;Ö. T. Orhun,&nbsp;Y. Kocaman,&nbsp;S. Okur","doi":"10.1111/jsap.70179","DOIUrl":"10.1111/jsap.70179","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To compare the effects of topical prilocaine and lidocaine, relative to topical 0.9% sodium chloride, on laryngeal reactivity in anaesthetised cats prior to endotracheal intubation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>In this prospective, randomised, controlled, double-blind study, 24 healthy adult cats were enrolled and allocated to topical prilocaine, topical lidocaine or topical 0.9% sodium chloride (<i>n</i> = 8/group) following anaesthesia with a standardised medetomidine-propofol protocol. The calculated volume of each local anaesthetic corresponding to 2 mg/kg, prepared from 2% stock solutions, was diluted with 0.9% sodium chloride to a standardised final volume of 0.5 mL and atomised onto the arytenoid and vocal fold regions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Relative to sodium chloride, prilocaine was associated with lower laryngeal reactivity at earlier time points (15 to 45 seconds), whereas lidocaine showed a later onset (from 60 seconds onward). Between 60 and 90 seconds, both prilocaine and lidocaine resulted in lower reactivity scores than sodium chloride, and no difference was observed between prilocaine and lidocaine at any assessed time point. No clinically evident adverse events were recorded during clinical monitoring of SpO₂, heart rate, respiratory pattern, mucous membrane colour and clinical signs such as local irritation, hypersalivation, vomiting, marked gagging, apnoea, desaturation, bradycardia or arrhythmia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>Topical prilocaine and lidocaine reduced laryngeal reactivity compared with topical 0.9% sodium chloride under the conditions of this study. The observed reductions occurred within the assessed 15 to 60 seconds interval; however, intubation conditions were not evaluated as comparative outcomes, and the clinical implications should therefore be interpreted in relation to laryngeal reactivity rather than direct measures of intubation performance.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 9","pages":"836-842"},"PeriodicalIF":1.5,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.70179","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148536093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experience with video-assisted thoracoscopic placement of pectus excavatum splints in kittens: six cases","authors":"G. Jones,&nbsp;Z. Peng,&nbsp;S. Gasson,&nbsp;R. Williams,&nbsp;K. T. Mankin,&nbsp;V. Dickerson","doi":"10.1111/jsap.70142","DOIUrl":"10.1111/jsap.70142","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This case series aims to describe the use of video-assisted thoracoscopic surgery for the treatment of pectus excavatum.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Six male, intact kittens, with a median age of 3.3 months (range, 2.5 to 4 months) and median weight of 1.75 kg (range, 0.44 to 2 kg), were presented to one of two referral institutions for evaluation of a concave sternal deformity. On presentation the kittens were found to have radiographically moderate (<i>n</i> = 3) to severe (<i>n</i> = 3) pectus excavatum of the caudal sternum with mild to moderate respiratory signs reported at home. Surgical correction included the use of video-assisted thoracoscopic surgery to facilitate external sternal splint placement. Use of video-assisted thoracoscopic surgery allowed for direct visualisation of needle passage to place the circumsternal sutures, potentially reducing the risk of complications given the proximity of intrathoracic vasculature and organs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>All patients recovered from anaesthesia uneventfully, and post-operative thoracic radiographs revealed reduction in sternal concavity and increase in thoracic height at the level of the original deformities. One cat suffered respiratory arrest 36 hours post-operatively for unknown reasons.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>Video-assisted thoracoscopic surgery-assisted external splint placement for pectus excavatum may help reduce intraoperative risks associated with pectus excavatum repair, though additional research is warranted.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 9","pages":"830-835"},"PeriodicalIF":1.5,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.70142","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147868919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of risk factors for surgical site infection following tibial plateau levelling osteotomy: a systematic review and meta-analysis","authors":"S. Cavalli,&nbsp;F. Aragosa,&nbsp;C. Montano,&nbsp;C. Caterino,&nbsp;G. Della Valle,&nbsp;G. Fatone","doi":"10.1111/jsap.70133","DOIUrl":"10.1111/jsap.70133","url":null,"abstract":"<p>The aim of this systematic review was to critically assess the available evidence regarding risk factors associated with surgical site infections following tibial plateau levelling osteotomy. This study aims to identify clinically relevant determinants of surgical site infection following tibial plateau levelling osteotomy and inform future preventive strategies. This systematic review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020. The review question was structured using the PECOS framework. Searches were performed in PubMed, Web of Science and Scopus without date restrictions, including all studies indexed up to June 2025. The search strategy combined terms related to surgical site infection, tibial plateau levelling osteotomy and dogs. Risk of bias was assessed across predefined methodological domains. The literature search yielded 436 results, and a total of 11 papers met the inclusion criteria. The study designs included two prospective clinical trials, one double-blinded randomised controlled trial and eight retrospective case series. Several risk factors for postoperative surgical site infection were investigated across the studies, with increased body weight being the most frequently identified. Most of the studies presented a high risk of bias in the domains of allocation concealment, blinding of participants and personnel and blinding of outcome assessment. In contrast, incomplete outcome data and selective reporting were generally assessed as low risk of bias. Knowledge of specific risk factors for surgical site infection after tibial plateau levelling osteotomy may support the clinician in tailoring antimicrobial prophylaxis and anticipating potential complications, thereby improving perioperative decision-making and patient outcomes.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 9","pages":"758-766"},"PeriodicalIF":1.5,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.70133","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147639119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of standard consensus definitions for infectious urinary tract disease in dogs and cats, a modified Delphi study","authors":"J. S. Weese,&nbsp;F. Allerton,&nbsp;K. Scahill,&nbsp;T. M. Sørensen,&nbsp;L. R. Jessen","doi":"10.1111/jsap.70127","DOIUrl":"10.1111/jsap.70127","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To develop consensus-based definitions for infectious urinary tract disease in dogs and cats.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>A modified Delphi approach was used to develop consensus on standard terminology and definitions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Four rounds of review were performed with two different expert and stakeholder audiences. The four rounds of review involved 19, 16, 90 and 52 participants, respectively. Consensus was reached for a collection of 29 terms and associated definitions, and one set of cut-off values.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>Standardisation of terminology is a foundational component of clinical communication, surveillance and guideline development. Unclear or variable definitions have commonly been present in studies of urinary tract disease in dogs and cats, causing confusion and hampering evidence assessment. Development of a set of standardised terms and definitions based on broad stakeholder consensus should assist with diagnosis, communication, surveillance and clinical research, improving the evidence base pertaining to infectious urinary tract disease and fostering improved clinical guidance.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 9","pages":"767-773"},"PeriodicalIF":1.5,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.70127","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147628004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}