Journal of Small Animal Practice最新文献

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Tensioning diaphragmoplasty for treating bilateral phrenic nerve paralysis in a dog. 张力膈成形术治疗犬双侧膈神经麻痹。
IF 1.7 2区 农林科学
Journal of Small Animal Practice Pub Date : 2025-02-11 DOI: 10.1111/jsap.13836
S Matsumoto, K Hosoya, S Kim, M Okumura
{"title":"Tensioning diaphragmoplasty for treating bilateral phrenic nerve paralysis in a dog.","authors":"S Matsumoto, K Hosoya, S Kim, M Okumura","doi":"10.1111/jsap.13836","DOIUrl":"https://doi.org/10.1111/jsap.13836","url":null,"abstract":"<p><p>A spayed female Miniature dachshund presented with a large mediastinal mass. During thymectomy, the left phrenic nerve, which was encircled by the neoplastic tissue, was resected en bloc with the tumour and the right phrenic nerve was damaged by thermal coagulation from electrosurgery. Postoperatively, the dog exhibited significant respiratory distress and paradoxical respiratory movement. Bilateral diaphragmatic paralysis was confirmed on inspiratory radiographs, and lack of structural abnormalities on thoracic computed tomography was noted. The dog collapsed 5 days postoperatively from respiratory fatigue. Thus, salvage surgery and tensioning diaphragmoplasty were performed. Briefly, The diaphragm was partially resected, primarily closed and reinforced with a polypropylene mesh sutured on the abdominal surface. Thereafter, the dog's condition improved significantly. The dog did not present with respiratory issues until she died of urothelial carcinoma on day 375. In conclusion, this surgical technique can be considered to re-establish the function of the diaphragm.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosis and fluoroscopic balloon dilation of nasopharyngeal stenosis concurrent to chronic displacement of the epiglottis in a pet rabbit. 家兔鼻咽狭窄并发会厌慢性移位的诊断和透视球囊扩张。
IF 1.7 2区 农林科学
Journal of Small Animal Practice Pub Date : 2025-02-11 DOI: 10.1111/jsap.13831
I Khelik, N Di Girolamo
{"title":"Diagnosis and fluoroscopic balloon dilation of nasopharyngeal stenosis concurrent to chronic displacement of the epiglottis in a pet rabbit.","authors":"I Khelik, N Di Girolamo","doi":"10.1111/jsap.13831","DOIUrl":"https://doi.org/10.1111/jsap.13831","url":null,"abstract":"<p><p>A 4-year-old, male neutered rabbit presented for chronic, antibiotics non-responsive upper respiratory disease. Computed tomography revealed sinusitis and nasopharyngeal stenosis resulting in upper airway obstruction. Deep nasal culture grew Pasteurella multocida. Airway fluoroscopy, performed with the rabbit conscious in a standing position, confirmed the location of the obstruction and subtle open mouth breathing. Pharyngoscopy further confirmed epiglottic displacement. In addition to antimicrobial therapy, three fluoroscopic balloon dilation procedures were performed to address the nasopharyngeal stenosis. Clinical signs improved during treatment course, and epiglottic displacement was resolved at the time of the third procedure. The rabbit was healthy 18 months after the last procedure. Nasopharyngeal stenosis should be considered a differential diagnosis for upper respiratory signs in rabbits. This rabbit was likely able to breathe through the oral cavity due to chronic epiglottic displacement secondary to the upper airway obstruction. Fluoroscopic-assisted balloon dilation was successful to treat this condition.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical outcomes and complications of tracheal resection and anastomosis in dogs and cats: 20 cases (2009–2022) 犬猫气管切除吻合20例临床结果及并发症分析(2009-2022)。
IF 1.7 2区 农林科学
Journal of Small Animal Practice Pub Date : 2025-02-05 DOI: 10.1111/jsap.13830
E. Gaudio, V. J. Lipscomb, M. Cantatore, K. Blacklock, M. Gosling, M. Jack, T. Charlesworth, C. J. Shales
{"title":"Clinical outcomes and complications of tracheal resection and anastomosis in dogs and cats: 20 cases (2009–2022)","authors":"E. Gaudio,&nbsp;V. J. Lipscomb,&nbsp;M. Cantatore,&nbsp;K. Blacklock,&nbsp;M. Gosling,&nbsp;M. Jack,&nbsp;T. Charlesworth,&nbsp;C. J. Shales","doi":"10.1111/jsap.13830","DOIUrl":"10.1111/jsap.13830","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To report clinical presentation, short-term outcome and complications of tracheal resection and anastomosis in dogs and cats.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Clinical records of pets treated with tracheal resection and anastomosis in seven UK-based veterinary referral centres were retrospectively reviewed (2009 to 2022).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twenty client-owned pets (eight dogs; 12 cats) were included. Clinical signs comprised dyspnoea (<i>n</i> = 15), stridor (<i>n</i> = 5), subcutaneous emphysema (<i>n</i> = 3), pneumothorax and pneumomediastinum (<i>n</i> = 1), coughing (<i>n</i> = 3), regurgitation (<i>n</i> = 1) and exercise intolerance (<i>n</i> = 1). Indication for surgery was traumatic tracheal rupture (<i>n</i> = 5), tracheal avulsion (<i>n</i> = 7), neoplasia (<i>n</i> = 5) and stenosis (<i>n</i> = 3). Complications occurred in 15 patients (75%). Non-anastomotic complications occurred in nine patients and consisted of cough (<i>n</i> = 5), self-resolving laryngeal paralysis (<i>n</i> = 1), surgical site infection (<i>n</i> = 1) and septic shock (<i>n</i> = 2). Anastomotic complications occurred in seven patients and consisted of anastomotic dehiscence (<i>n</i> = 1), tracheal stenosis (<i>n</i> = 4) and fatal respiratory failure (<i>n</i> = 2). Revision surgery was performed in two dogs due to anastomotic dehiscence and stenosis, and tracheal stenting was performed in one cat due to stenosis. Sixteen patients survived to hospital discharge and 14 survived to latest follow-up (median: 119 days; range: 14 to 1744). Outcome was scored as excellent in five, good in seven, fair in two and poor in six patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>Tracheal resection and anastomosis is the surgical technique of choice to reconstruct tracheal defects. Although more than half of the patients recovered well, high morbidity and mortality rates were documented. This may be due to the severe comorbidities affecting most tracheal resection and anastomosis patients, as well as the client's decision against further treatment when facing serious post-operative complications.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"66 5","pages":"335-345"},"PeriodicalIF":1.7,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic factors and long-term outcome in dogs diagnosed with primary and secondary immune thrombocytopenia in Ireland 爱尔兰原发性和继发性免疫性血小板减少症犬的预后因素和长期预后
IF 1.7 2区 农林科学
Journal of Small Animal Practice Pub Date : 2025-01-29 DOI: 10.1111/jsap.13833
E. López-Bailén, A. Duclos, D. Mullany, K. Le Boedec, B. Cuq
{"title":"Prognostic factors and long-term outcome in dogs diagnosed with primary and secondary immune thrombocytopenia in Ireland","authors":"E. López-Bailén,&nbsp;A. Duclos,&nbsp;D. Mullany,&nbsp;K. Le Boedec,&nbsp;B. Cuq","doi":"10.1111/jsap.13833","DOIUrl":"10.1111/jsap.13833","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The objectives of this study were to describe the outcome and prognostic factors in dogs diagnosed with primary and secondary immune thrombocytopenia (ITP).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Medical records of dogs diagnosed with primary and secondary ITP in a referral hospital in Ireland were retrospectively evaluated. Short- and long-term survivals were analysed using Cox proportional-hazards regression models.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Medical records from 49 dogs were included. Primary and secondary ITP were diagnosed in 81.25% and 18.75% of dogs, respectively. The survival rate was 69% at 2 weeks (95% confidence interval [CI]: 0.54 to 0.80), 63% at 3 months (95% CI: 0.48 to 0.75) and 51% at 2 years (95% CI: 0.37 to 0.65). The overall median survival time was 985 days (primary ITP only: 1084 days; secondary ITP only: 225 days). Dogs surviving 30 days post-diagnosis had a median long-term survival time of 10 years. A lower haematocrit was negatively associated with survival [hazard ratio (HR) 0.96, 95% CI: 0.92 to 0.99]. Neutrophilia (HR: 0.44, 95% CI: 0.20 to 0.96) was associated with a 66% decreased risk of death. Band neutrophilia was associated with shorter hospitalisation (regression coefficient −3.56, 95% CI: −5.70 to -1.42). Presence of petechiae and ecchymoses (regression coefficient 2.41, 95% CI: 0.41 to 4.42), and the use of a second-line immunosuppressive agent (SLI) (regression coefficient 2.11, 95% CI: 0.11 to 4.12) were significantly associated with longer hospitalisation but not with survival.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>A lower haematocrit was the only variable associated with a worse prognosis in dogs diagnosed with ITP. Dogs with confirmed secondary ITP had an overall shorter median survival time. Dogs surviving over 30 days had an excellent prognosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"66 5","pages":"305-313"},"PeriodicalIF":1.7,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.13833","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraoperative methylene blue staining is effective as a single mapping technique in the identification of sentinel lymph nodes in dogs with low-grade mast cell tumours 术中亚甲基蓝染色是一种有效的单一定位技术,用于识别低级别肥大细胞肿瘤犬前哨淋巴结。
IF 1.7 2区 农林科学
Journal of Small Animal Practice Pub Date : 2025-01-27 DOI: 10.1111/jsap.13832
S. Zanardi, D. Guerra, S. Sabattini, A. Foglia, S. Del Magno, V. Cola, L. Pisoni, L. Ciammaichella, E. Faroni, C. Agnoli, A. Renzi, L. Marconato
{"title":"Intraoperative methylene blue staining is effective as a single mapping technique in the identification of sentinel lymph nodes in dogs with low-grade mast cell tumours","authors":"S. Zanardi,&nbsp;D. Guerra,&nbsp;S. Sabattini,&nbsp;A. Foglia,&nbsp;S. Del Magno,&nbsp;V. Cola,&nbsp;L. Pisoni,&nbsp;L. Ciammaichella,&nbsp;E. Faroni,&nbsp;C. Agnoli,&nbsp;A. Renzi,&nbsp;L. Marconato","doi":"10.1111/jsap.13832","DOIUrl":"10.1111/jsap.13832","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The aim of this prospective study was to assess the association between methylene blue staining pattern and the presence of histologic nodal metastasis in dogs with low-grade mast cell tumour in low-resource settings for the efficient diagnosis of lymphatic spread.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Dogs with a single, cytologically low-grade mast cell tumour and no documented distant metastases were prospectively included and underwent surgery. Along with primary mast cell tumour removal, intraoperative sentinel lymph node mapping with peritumoral mast cell tumour injection and regional lymph node excision, regardless of whether blue dye was visible in the lymph node, were performed. Association between the lymph nodes with dye uptake (stained) and their metastatic status was evaluated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twenty-five dogs were enrolled, and at least one stained lymph node was identified in 22 (88%) of them. A total of 49 lymphocentres were surgically inspected, and a total of 53 lymph nodes were removed. Twenty-nine (54.7%) lymph nodes were stained, and 24 (45.3%) were unstained. Among the 29 stained lymph nodes, there were seven (24.1%) HN0, seven (24.1%) HN1, seven (24.1%) HN2 and eight (27.7%) HN3. Among the 24 unstained lymph nodes, 17 (70.8%) were HN0 and seven (29.2%) were HN1. No complications related to methylene blue injection were recorded.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>Peritumoral methylene blue injection is a cost-effective alternative technique for detecting sentinel lymph node for dogs with mast cell tumours, particularly in economically constrained settings. All metastatic lymph nodes (HN2/HN3) were stained, and all unstained lymph nodes were non-metastatic (HN0/HN1).</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"66 5","pages":"321-327"},"PeriodicalIF":1.7,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.13832","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary uterine large granular lymphocyte lymphoma in an ovariectomised cat 切除卵巢的猫原发性子宫大颗粒淋巴细胞淋巴瘤。
IF 1.7 2区 农林科学
Journal of Small Animal Practice Pub Date : 2025-01-19 DOI: 10.1111/jsap.13824
Y. Cuzzupè, B. Banco, N. Boffa, A. Arcangeli, R. Franchi, D. Volpi, R. Finotello
{"title":"Primary uterine large granular lymphocyte lymphoma in an ovariectomised cat","authors":"Y. Cuzzupè,&nbsp;B. Banco,&nbsp;N. Boffa,&nbsp;A. Arcangeli,&nbsp;R. Franchi,&nbsp;D. Volpi,&nbsp;R. Finotello","doi":"10.1111/jsap.13824","DOIUrl":"10.1111/jsap.13824","url":null,"abstract":"<p>Primary uterine lymphoma is an extremely rare disease. An 11-year-old spayed female domestic short-haired cat presented with a 3-month history of mucopurulent vaginal discharge, lethargy, acute vomiting and constipation. Physical examination revealed vulvar swelling, purulent discharge and a mass in the mid-caudal abdomen. A CT scan identified a large uterine mass, displacing the colon dorsally and the urethra ventrally. A hysterectomy was performed. Histology and immunohistochemistry confirmed a T-cell uterine transmural medium to large cell lymphoma. One-month post-surgery, an abdominal ultrasound showed thickening of the jejunal loops, enlarged lymph nodes and nodular peritoneal lesions at the surgical site. Cytology raised suspicion of large granular lymphocyte lymphoma, confirmed by anti-Granzyme B immunohistochemistry on the uterine tissue specimen. The final diagnosis was primary uterine large granular lymphocyte lymphoma, marking the first reported case in small animal oncology.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"66 5","pages":"353-357"},"PeriodicalIF":1.7,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiographic diagnosis of a catheter rupture in a ventriculoperitoneal shunt following head trauma in a dog 犬头部外伤后脑室腹腔分流管破裂的影像学诊断。
IF 1.7 2区 农林科学
Journal of Small Animal Practice Pub Date : 2025-01-15 DOI: 10.1111/jsap.13802
L. Martin Garcia, R. Gutierrez-Quintana, V. Gonzalo Nadal, A. Cloquell Miro
{"title":"Radiographic diagnosis of a catheter rupture in a ventriculoperitoneal shunt following head trauma in a dog","authors":"L. Martin Garcia,&nbsp;R. Gutierrez-Quintana,&nbsp;V. Gonzalo Nadal,&nbsp;A. Cloquell Miro","doi":"10.1111/jsap.13802","DOIUrl":"10.1111/jsap.13802","url":null,"abstract":"<p>Four-year-old male neutered Border Collie presented with a 3-month history of proprioceptive ataxia, low head carriage, delayed postural reactions on thoracic limbs and neck pain. The patient was diagnosed with congenital obstructive hydrocephalus with secondary syringohydromyelia and underwent a successful ventriculoperitoneal shunt (VPS) surgery. A year after surgery, the dog presented with the same neurological signs 2 weeks after suffering head trauma. On manual palpation, the VPS valve was firmly filled and non-compressible suggesting the presence of an occlusion distally to the valve. Right lateral and dorsoventral radiographic images of the neck, thorax and abdomen were obtained to assess the integrity of the shunt catheters and valve. Dorsoventral images showed a rupture of the distal catheter proximally to the valve, which was easily missed in the lateral views (Fig 1A, B). Computed tomography confirmed the radiological findings (Fig 1C), and no other abnormalities were noted. The patient underwent revision surgery (Fig 1D), and the affected part of the shunt catheter and the valve were replaced. The patient recovered successfully and 1 month after surgery, neurological examination demonstrated mild proprioceptive ataxia, with the rest of the signs resolved. As previously described in the veterinary literature, complications following VPS placement include ventricular catheter migration, infection, kinking of the catheter, disconnection between the catheters and the valve, under or excessive drainage and abdominal skin necrosis. To the author's knowledge, this is the first case of VPS rupture following head trauma, which should be considered in patients with a history of head trauma after shunt placement who present with relapse of neurological signs. This case emphasises the importance of performing orthogonal radiographic views of the shunting route, and the potential use of the manual evaluation (by pumping) of the valve reservoir for testing VPS sufficiency.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"66 3","pages":"214"},"PeriodicalIF":1.7,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.13802","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Magnetic resonance manifestation of diffuse osteopenia in a cat with presumed nutritional secondary hyperparathyroidism, hypocobalaminaemia and thiamine deficiency 推测为营养性继发性甲状旁腺功能亢进、低钴胺血症和硫胺素缺乏症的猫弥漫性骨质减少的磁共振表现
IF 1.7 2区 农林科学
Journal of Small Animal Practice Pub Date : 2025-01-15 DOI: 10.1111/jsap.13815
A. Skarbek, C.-G. Danciu, J. Fenn, J. Klever
{"title":"Magnetic resonance manifestation of diffuse osteopenia in a cat with presumed nutritional secondary hyperparathyroidism, hypocobalaminaemia and thiamine deficiency","authors":"A. Skarbek,&nbsp;C.-G. Danciu,&nbsp;J. Fenn,&nbsp;J. Klever","doi":"10.1111/jsap.13815","DOIUrl":"10.1111/jsap.13815","url":null,"abstract":"<p>A 1-year-old male entire Bengal cat presented for weakness and progressive gait abnormality over 5 days. The cat was fed raw or cooked chicken since a kitten and was diagnosed with left-sided femoral neck fracture after a fall several months prior. Neurological examination revealed appropriate mentation, intermittent intention tremor, non-ambulatory tetraparesis with generalised proprioceptive ataxia, reduced postural reactions, intact spinal reflexes in all limbs and unremarkable cranial nerves. Neuroanatomical localisation was C1-5 spinal cord segments and/or cerebellum. Haematology revealed neutrophilia [23.88 × 109/L, reference interval (RI): 2.50 to 12.50 × 109/L]. Serum biochemistry revealed hypernatraemia (160.0 mmoL/L, RI: 145.0 to 157.0 mmoL/L), hypocalcaemia (1.96 mmoL/L, RI: 2.11 to 2.90 mmoL/L), hypercholesterolaemia (5.2 mmoL/L, RI: 2.2 to 4.0 mmoL/L), increased alanine transaminase (159 U/L, RI: 5 to 60 U/L) and hypocobalaminaemia (154.0 ng/L, RI: &gt;200.0 ng/L). The radiographs of the skull, vertebral column and thoracic limbs revealed diffuse osteopenia of the axial and appendicular skeleton, including decreased mineral opacity, cortical thinning and double cortical lign in the left radius. The included bones were enlarged and showed abnormal shape, including enlarged dens protruding into the vertebral canal. MRI of the head and cervical region demonstrated unremarkable brain, marked diffusely increased T2-weighted (T2w), T1w, short tau inversion recover (STIR) signal intensity, loss of cortical and trabecular bone distinction and strongly contrast enhancing axial skeleton. The radiographic and MRI features were considered secondary to osteopenia and fibrous osteodystrophy related to nutritional hyperparathyroidism. Due to the cerebellar signs and dietary history, thiamine deficiency was suspected alongside the hypocobalaminaemia. A balanced diet, cobalamin and thiamine supplementation led to complete clinical recovery. Decreased cellular marrow components, premature red-to-yellow conversion and increased fat content could elicit T1w skeletal hyperintensity. Further MRI signal changes including contrast enhancement are not fully understood; however, incomplete red-to-yellow conversion and serous atrophy of the bone marrow are suspected (Fig 1).</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"66 4","pages":"296"},"PeriodicalIF":1.7,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.13815","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute and chronic systemic inflammation associated with canine nodular splenic lesions composed of heterogeneous cell components: four cases (2020-2024) 犬科脾结节性非均质细胞组成病变的急性和慢性全系统炎症:4例(2020-2024)。
IF 1.7 2区 农林科学
Journal of Small Animal Practice Pub Date : 2025-01-15 DOI: 10.1111/jsap.13826
K. Mourou, Y. Abou Monsef, S. Belluco, M. Penent, M. Delverdier, M. Hugonnard, F. Granat, R. Lavoue, M. Mantelli
{"title":"Acute and chronic systemic inflammation associated with canine nodular splenic lesions composed of heterogeneous cell components: four cases (2020-2024)","authors":"K. Mourou,&nbsp;Y. Abou Monsef,&nbsp;S. Belluco,&nbsp;M. Penent,&nbsp;M. Delverdier,&nbsp;M. Hugonnard,&nbsp;F. Granat,&nbsp;R. Lavoue,&nbsp;M. Mantelli","doi":"10.1111/jsap.13826","DOIUrl":"10.1111/jsap.13826","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To describe the clinical presentation and clinicopathological findings of dogs with nodular splenic lesions composed of heterogeneous cell components associated with systemic inflammation and to provide information on the outcome after surgical resection.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Medical records were searched for dogs with histologically and immunohistochemically characterised nodular splenic lesions with mixed stromal, histiocytic and lymphoid cells and the presence of systemic inflammatory markers at the time of diagnosis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Four dogs were included, of which three had an undifferentiated splenic stromal sarcoma and one had a splenic leiomyosarcoma. Fever and abdominal pain were reported in three and four cases, respectively. All dogs showed hyperglobulinaemia and marked changes in the serum protein electrophoresis profile. C-reactive protein and fibrinogen concentrations were both increased in three cases. These abnormalities completely resolved after splenectomy. Moreover, two dogs had concomitant glomerular disease and one dog had liver amyloidosis. Three dogs were still alive and asymptomatic 1, 6 and 9 months after surgery. One dog died 16 months after the initial presentation due to complications related to progressive renal failure.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>Based on this report, nodular splenic lesions with heterogeneous cell components may directly be associated with a pro-inflammatory state and should be considered as part of the differential diagnosis of fever and hyperglobulinaemia in dogs. Furthermore, early recognition and treatment of these lesions could reduce the risk of systemic complications potentially associated with amyloid deposit and organ failure.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"66 4","pages":"280-290"},"PeriodicalIF":1.7,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.13826","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Compartmental location of middle ear inflammatory polyps in cats: 9 cases (2021-2023) 猫中耳炎性息肉的腔室定位:9例(2021-2023)。
IF 1.7 2区 农林科学
Journal of Small Animal Practice Pub Date : 2025-01-15 DOI: 10.1111/jsap.13811
C. Bohin, M. Garcia, C. Bertinot, M. Graille, A. Bernardé
{"title":"Compartmental location of middle ear inflammatory polyps in cats: 9 cases (2021-2023)","authors":"C. Bohin,&nbsp;M. Garcia,&nbsp;C. Bertinot,&nbsp;M. Graille,&nbsp;A. Bernardé","doi":"10.1111/jsap.13811","DOIUrl":"10.1111/jsap.13811","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To report the compartmental location of feline aural inflammatory polyps within the tympanic bulla.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Nine client-owned cats with clinical signs and middle ear filling consistent with feline aural inflammatory polyps were prospectively pre-selected and underwent unilateral or bilateral ventral bulla osteotomy. Preoperative and surgical findings, complications and outcomes were recorded. Tissues obtained from the ventromedial compartment and from the dorsolateral compartment of the tympanic bulla were submitted separately for histological examination. Definitively selected cats were those having feline aural inflammatory polyps in at least one compartment of their operated tympanic bulla.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Ten ventral bulla osteotomies were performed on nine cats. Feline aural inflammatory polyps were histologically diagnosed in both compartments of all tympanic bullas. There were no intraoperative complications. Apart from Horner's syndrome on the ipsilateral eye following surgeries, post-operative complications were rare. This is the first study that documents the presence of feline aural inflammatory polyps in both compartments of the tympanic bulla in all cats with aural involvement.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>Should a complete excision of feline aural inflammatory polyps be desired, complete debridement of both compartments of the tympanic bulla is required. Traction-avulsion techniques using approaches of tympanic bulla with no visit of the ventromedial compartment may not completely resolve the condition.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"66 3","pages":"197-202"},"PeriodicalIF":1.7,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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