Journal of Small Animal Practice最新文献

{"title":"Fulkerson-based oblique novel technique (FONT) to treat concurrent cranial cruciate ligament disease and medial patellar luxation in the dog","authors":"P. Agüera-Espejo,&nbsp;J. L. Fontalba-Navas,&nbsp;I. Calvo,&nbsp;E. Senis-Alvarez,&nbsp;A. Artiles-Vizcaino,&nbsp;T. Guerrero,&nbsp;J. Rodriguez-Quiros","doi":"10.1111/jsap.70117","DOIUrl":"10.1111/jsap.70117","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To assess the theoretical and morphometric effects of a novel oblique tibial tuberosity osteotomy technique designed to enable simultaneous advancement and lateralisation of the tibial tuberosity using a tibial tuberosity advancement cage for the surgical treatment of concurrent cranial cruciate ligament disease and medial patellar luxation in dogs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Design</h3>\u0000 \u0000 <p>Computational modelling and <i>ex vivo</i> cadaveric study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Fourteen pelvic limbs from mixed-breed dog cadavers (15.8 to 25.3 kg).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Theoretical calculations were performed to quantify tibial tuberosity displacement based on osteotomy angle and cage size using trigonometric principles. A 3D computer simulation was used to evaluate four osteotomy angles (0°, 25°, 30° and 35°). Oblique osteotomies targeting 30° were performed freehand on 14 cadaveric tibiae. Pre- and postoperative CT scans were used to measure the actual osteotomy angles achieved. Shapiro–Wilk and paired <i>t</i>-tests were used to assess data normality and statistical significance, respectively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean osteotomy angle achieved was 32.27° (SD ±3.4°), significantly different from the target angle of 30°. Lateralisation and advancement percentages for the tibial tuberosity were as follows: 0°: 0% lateralisation, 100% advancement; 25°: 42.3%, 90.7%; 30°: 50.0%, 86.7%; 35°: 57.3% and 82.0%, respectively. For all cage sizes (3, 6, 9 and 12 mm), lateral translation consistently exceeded the target value, whereas cranial translation was consistently lower than the target, showing statistically significant differences.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Simultaneous tibial tuberosity advancement and lateralisation could be achieved using an oblique osteotomy and standard tibial tuberosity advancement cage. However, freehand osteotomies demonstrate limited accuracy, suggesting that cutting guides may improve consistency.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>This technique offers a novel approach to treat dogs with concurrent cranial cruciate ligament disease and medial patellar luxation, potentially simplifying surgical management through a single, oblique osteotomy.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 8","pages":"695-701"},"PeriodicalIF":1.5,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147480944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of an ELISA assay for measurement of the metabolite of serotonin, 5-hydroxyindole acetic acid (5-HIAA), in canine urine","authors":"D. Castillo,&nbsp;A. Swallow,&nbsp;T. Williams,&nbsp;P. Watson","doi":"10.1111/jsap.70123","DOIUrl":"10.1111/jsap.70123","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Serotonin (5-hydroxytryptophan), implicated in a number of canine diseases, has a very short half-life in the serum. Urine concentration of its breakdown product 5-hydroxyindole acetic acid after an 8 hour fast is a more reliable measure of circulating serotonin in humans. This study aimed to validate a commercially available ELISA assay to measure 5-hydroxyindole acetic acid concentrations in canine urine by comparing the analytical performance with the gold standard of liquid chromatography-tandem mass spectrometry.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Urine was collected from 26 dogs undergoing routine diagnostic investigations at one referral centre and rapidly processed and stored prior to testing for 5-hydroxyindole acetic acid using the two methods. Deming regression and Bland–Altman analyses were used to compare the results between the two methods.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The ELISA demonstrated acceptable precision and repeatability (coefficient of variation &lt;20%). There was good agreement between the two methods (bias 0.92 μmol/L; 95% limits of agreement −6.44 to 8.29 μmol/L), although the ELISA was not tested at values close to the upper-end of the claimed analytical measurement range limit. The ELISA was likely to be very reliable at low concentrations but may exceed acceptable error limits at high concentrations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>A commercially available ELISA was validated to measure urine 5-hydroxyindole acetic acid. This is a less invasive method than blood sampling for serotonin and should give a more reliable indication of long-term serum serotonin concentrations. More studies of normal and diseased dogs are needed to confirm these findings before applying them in a clinical setting.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 8","pages":"680-685"},"PeriodicalIF":1.5,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.70123","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147512868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computed tomographic features of presumed normal palatine tonsils in 140 dogs","authors":"N. Leong,&nbsp;R. Drees,&nbsp;H. Dirrig","doi":"10.1111/jsap.70132","DOIUrl":"10.1111/jsap.70132","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The purpose of this retrospective study was to describe the CT features of presumed normal canine palatine tonsils.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Pre- and post-contrast head CT studies of 140 dogs without tonsillar disease were included. Subjective evaluation of palatine tonsils included contrast enhancement pattern, differentiation from surrounding soft tissues and presence of gas or mineral within the tonsillar fossae. Quantitative measurements included pre- and post-contrast attenuation, width, height and length. Relationships between palatine tonsillar size and age, bodyweight, brachycephalic <i>versus</i> normocephalic conformation and concurrent regional disease were investigated. Bodyweight-based ranges (≤10.0 kg, 10.1 to 25.0 kg and &gt;25.0 kg) for tonsillar sizes were established to assess differences in tonsillar size across weight categories.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Palatine tonsils were identified on CT examination in all dogs. 52.9% palatine tonsils were poorly differentiated from adjacent soft tissues in post-contrast series, 86.1% tonsillar fossae contained gas and 7.9% contained mineral. Mean palatine tonsillar width was 6.9 mm (SD 2.2 mm), height 6.5 mm (SD 2.0 mm) and length 19.1 mm (SD 4.5 mm). Median attenuation pre-contrast was 50.8 HU (range 22.6 to 82.1 HU), significantly increasing to 89.4 HU post-contrast (range 49.7 to 128.0 HU). Tonsillar size was negatively correlated with age and positively correlated with bodyweight. There were statistically significant increases in tonsillar size with each ascending bodyweight range. No statistically significant size differences were found between brachycephalic and normocephalic breeds, nor between dogs with or without concurrent regional disease.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>These findings may serve as informative references for evaluating palatine tonsils on CT examinations in healthy dogs and provide comparisons for assessing tonsillar pathology.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 8","pages":"739-748"},"PeriodicalIF":1.5,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.70132","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147674435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gross and cytological appearance of oral gout in a crested gecko (Correlophus ciliatus) with end-stage nephropathy","authors":"I. Alvarado-Hidalgo,&nbsp;A. A. Kuehr,&nbsp;K. D. Lee,&nbsp;A. Newman,&nbsp;A. D. Miller,&nbsp;N. Di Girolamo","doi":"10.1111/jsap.70128","DOIUrl":"10.1111/jsap.70128","url":null,"abstract":"","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 8","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral ischaemic neuromyopathy due to axillary artery thrombosis in a dog","authors":"K. M. Santifort,&nbsp;M. Meeusen,&nbsp;M. Beukers","doi":"10.1111/jsap.70126","DOIUrl":"10.1111/jsap.70126","url":null,"abstract":"","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 8","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147521226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical presentation and outcome of Mycobacterium abscessus infection in six dogs – a retrospective study","authors":"L. Kher,&nbsp;A. R. Hoffmann,&nbsp;S. A. Walton,&nbsp;D. Santoro","doi":"10.1111/jsap.70114","DOIUrl":"10.1111/jsap.70114","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p><i>Mycobacterium abscessus</i> is a rapidly growing non-tuberculous mycobacterium known for intrinsic antimicrobial resistance. While well characterised in humans, reports in dogs remain limited. To describe the clinical presentation, diagnostic findings, treatment strategies and outcomes of <i>Mycobacterium abscessus</i> infections in six dogs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Canine medical records between 2017 and 2025 were retrospectively reviewed. Dogs were included based on confirmed <i>Mycobacterium abscessus</i> infection by mycobacterial culture and/or polymerase chain reaction. Data collected included signalment, clinical signs, diagnostics, treatment protocols, outcomes and follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Six dogs of various breeds and ages were included in the study. Two dogs presented with chronic respiratory signs (2/6) (coughing and hacking), whereas the other four had cutaneous/subcutaneous nodules with draining tracts, frequently located on the right side of the trunk. All cases occurred during the winter months. Diagnosis was confirmed by culture and polymerase chain reaction in all cases; one isolate was additionally identified <i>via</i> MALDI-TOF. Cutaneous histopathology (performed in two dogs) showed pyogranulomatous dermatitis and panniculitis. Clarithromycin was the primary treatment in all dogs. Polytherapy with the use of additional antimicrobials varied. Clinical outcomes/follow-up were available for five dogs, with one dog fully recovered, one relapsed after discontinuation of therapy and two were euthanased. Two dogs had a concurrent staphylococcal infection.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p><i>Mycobacterium abscessus</i> infections in dogs can mimic other chronic infections and present significant diagnostic and therapeutic challenges. Disease patterns (respiratory or cutaneous) closely resemble human cases. Culture and polymerase chain reaction are essential for diagnosis, and clarithromycin remains a key therapeutic option despite variable susceptibility.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 8","pages":"686-694"},"PeriodicalIF":1.5,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147473420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk assessment of canine periodontal disease: insights from owner-reported health questionnaires","authors":"A. A. Jemmett,&nbsp;C. Salt,&nbsp;L. A. Perry,&nbsp;C. O'Flynn","doi":"10.1111/jsap.70121","DOIUrl":"10.1111/jsap.70121","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To identify risk factors associated with periodontal disease in pet dogs, based on detailed owner-reported demographic, health and behaviour survey data.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>A total of 12,753 pet owners completed a one-time questionnaire that included questions concerning their pet's demographics and health.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Overall periodontal disease prevalence was 50.5% (95% CI 0.50 to 0.51). Multivariable logistic regression analysis identified age, breed characteristics, oral diagnoses, symptoms and oral care habits as key risk factors for periodontal disease. Age was strongly associated with periodontal disease, with dogs aged ≥8 years at highest risk (OR = 1.37 to 2.43) and those under 4 years at lowest risk (OR = 0.30 to 0.64). Several breeds were at significantly increased risk, including American cocker spaniels (OR = 2.52, 95% CI 1.63 to 4.00, <i>P</i> &lt; .001) and Papillons (OR = 2.36, 95% CI 1.56 to 3.65), while English Bulldogs exhibited the lowest odds of periodontal disease (OR = 0.12, 95% CI 0.07 to 0.20). Symptoms such as halitosis (OR = 2.03, 95% CI 1.75 to 2.34) and resistance to head touch (OR = 1.66, 95% CI 1.28 to 2.15) were associated with significantly increased periodontal disease odds.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>These findings highlight important risk factors associated with periodontal disease that may contribute to earlier identification and prevention.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":"67 8","pages":"721-733"},"PeriodicalIF":1.5,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jsap.70121","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147486400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survival outcomes in dogs treated with vinorelbine-based adjuvant treatment following surgical resection of grade II and III pulmonary carcinoma.","authors":"N Wong, L Brockley, S Rajan, J Yu","doi":"10.1111/jsap.70183","DOIUrl":"https://doi.org/10.1111/jsap.70183","url":null,"abstract":"<p><strong>Objectives: </strong>Pulmonary carcinoma in dogs is commonly managed with surgical resection; however, the role of adjuvant chemotherapy for grade II and III carcinomas remains unclear. This retrospective multicentre study investigated the outcomes in dogs treated with vinorelbine-based adjuvant treatment (as monotherapy or combined chemotherapy) following surgical resection, compared to surgical resection alone.</p><p><strong>Materials and methods: </strong>Fifty-six dogs with histologically confirmed grade II and III pulmonary carcinoma were evaluated in this study. Thirty-six dogs received vinorelbine-based adjuvant treatment post-surgery based on owner decision following consultation with a veterinary oncologist. Twenty dogs underwent surgical resection alone. The progression-free survival and overall survival were assessed using Cox proportional hazards analysis.</p><p><strong>Results: </strong>The median progression-free survival was longer in dogs treated with vinorelbine-based adjuvant treatment (232 days, 95% CI 137 to 385 days) compared to dogs treated with surgical resection only (124 days, 95% CI 36 to 220 days) (HR 0.39, 95% CI 0.21 to 0.70, P = .003). The median overall survival was longer in dogs treated with vinorelbine-based adjuvant treatment (316 days, 95% CI 180 to 457 days) compared to dogs treated with surgical resection only (124 days, 95% CI 43 to 256 days) (HR 0.31, 95% CI 0.17 to 0.58, P < .001). The use of vinorelbine-based adjuvant treatment and tumour grade were independent predictors of progression-free survival and survival (P < .001).</p><p><strong>Clinical significance: </strong>These findings suggest that vinorelbine-based adjuvant treatment is associated with longer progression-free survival and overall survival in dogs with grade II and III pulmonary carcinoma following surgical resection in this cohort. However, the variability in treatment protocols used in this study limits our ability to draw definitive conclusions regarding treatment efficacy.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148669790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The incidence of vaccine-associated sarcomas in cats: a systematic review and meta-analysis.","authors":"F Emdin, S G Naro, P M Hoang, K A Brown, N Daneman, J S Weese","doi":"10.1111/jsap.70176","DOIUrl":"https://doi.org/10.1111/jsap.70176","url":null,"abstract":"<p><strong>Objectives: </strong>Feline injection-site sarcoma is a rare but serious adverse event associated with vaccination in cats. Published estimates of feline injection-site sarcoma incidence vary widely, contributing to uncertainty in clinical decision-making and incidence communication.</p><p><strong>Materials and methods: </strong>We conducted a systematic review and meta-analysis to estimate the incidence of feline injection-site sarcoma following vaccination in cats and to assess the certainty of the evidence. MEDLINE (via Ovid), CAB Abstracts and Web of Science were searched from database inception through January 2026 using terms related to cats, vaccination, sarcomas and adverse vaccine events. Eligible studies reported quantitative estimates of feline injection-site sarcoma incidence, including incidence, incidence rate or measures of association. Two reviewers independently screened studies, extracted data and assessed study quality using the Joanna Briggs Institute checklist for prevalence studies. Incidence estimates were calculated using random-effects meta-analysis. Certainty of evidence was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation framework.</p><p><strong>Results: </strong>Eight studies met inclusion criteria, representing 14,059,036 vaccinations and 411 reported feline injection-site sarcoma cases. Study-level incidence estimates ranged from near zero to substantially higher values per vaccination. The incidence was 8.8 feline injection-site sarcoma cases per 100,000 vaccinations (95% CI 0.8 to 100.6), equivalent to approximately 1 feline injection-site sarcoma per 10,000 vaccinations. Between-study heterogeneity was very high (I² = 99.61%), reflecting differences in study design, surveillance systems and reporting methods. Subgroup analyses comparing studies conducted before and after 2000 found no significant difference in feline injection-site sarcoma incidence; although lower incidence estimates were observed in later studies, suggesting that the introduction of non-adjuvanted vaccines may have reduced feline injection-site sarcoma incidence. Overall certainty of evidence was rated as very low due to high risk of bias and imprecision.</p><p><strong>Clinical significance: </strong>Feline injection-site sarcoma remains a rare adverse event associated with vaccination in cats. Current evidence supports a low absolute incidence and reinforces the importance of routine feline vaccination while underscoring the need for improved surveillance and higher quality epidemiologic studies.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148630785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Euthanasia rates and risk factors for euthanasia in dogs diagnosed with diabetes mellitus in Australian primary care practices: 2078 cases (2008-2017).","authors":"E Roberts, M A Stevenson, C S Mansfield","doi":"10.1111/jsap.70177","DOIUrl":"https://doi.org/10.1111/jsap.70177","url":null,"abstract":"<p><strong>Objectives: </strong>Detailed assessments of euthanasia rates of dogs with diabetes mellitus in Australian primary care practice and evaluation of associated risk factors have not been performed. Study objectives were to describe the euthanasia timing in this population and identify patient characteristics at diagnosis that increased the probability of euthanasia.</p><p><strong>Materials and methods: </strong>Records of dogs diagnosed with diabetes mellitus in primary care practice (n = 2078) during 2008 to 2017, inclusively, were sourced through VetCompass Australia. For cases that were euthanised, reasons were attributed to being related to diabetes mellitus or not. Time to euthanasia post-diagnosis was described using Kaplan-Meier survival curves. A Cox proportional hazards regression model was developed to identify risk factors for euthanasia following diabetes mellitus diagnosis.</p><p><strong>Results: </strong>The cumulative percentage of dogs euthanised for diabetes-related reasons at diagnosis, and within 6 and 12 months of diagnosis was 13%, 46% and 53%, respectively. During the first 12 months post-diagnosis, dogs that were entire [HR 1.9 (95% CI 1.6 to 2.3)], ≥10 years of age [HR 2.4 (95% CI 2.1 to 2.7)], female [HR 1.1 (95% CI 1.0 to 1.3)] and of breeds at higher risk of developing diabetes mellitus [HR 1.2 (95% CI 1.0 to 1.4)] had an increased daily hazard of euthanasia. Quality of life was the most frequently reported reason for euthanasia.</p><p><strong>Clinical significance: </strong>This study documents higher euthanasia rates among dogs with diabetes mellitus within the first year of diagnosis than previously reported. The findings help identify cases where additional owner support could be warranted.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148620657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}