Journal of Sleep Research最新文献

{"title":"Sleep neuroimaging: Review and future directions.","authors":"Mariana Pereira, Xinyuan Chen, Anastasiya Paltarzhytskaya, Yibran Pacheсo, Nils Muller, Leonore Bovy, Xu Lei, Wei Chen, Haoran Ren, Chen Song, Laura D Lewis, Thien Thanh Dang-Vu, Michael Czisch, Dante Picchioni, Jeff Duyn, Philippe Peigneux, Enzo Tagliazucchi, Martin Dresler","doi":"10.1111/jsr.14462","DOIUrl":"https://doi.org/10.1111/jsr.14462","url":null,"abstract":"<p><p>Sleep research has evolved considerably since the first sleep electroencephalography recordings in the 1930s and the discovery of well-distinguishable sleep stages in the 1950s. While electrophysiological recordings have been used to describe the sleeping brain in much detail, since the 1990s neuroimaging techniques have been applied to uncover the brain organization and functional connectivity of human sleep with greater spatial resolution. The combination of electroencephalography with different neuroimaging modalities such as positron emission tomography, structural magnetic resonance imaging and functional magnetic resonance imaging imposes several challenges for sleep studies, for instance, the need to combine polysomnographic recordings to assess sleep stages accurately, difficulties maintaining and consolidating sleep in an unfamiliar and restricted environment, scanner-induced distortions with physiological artefacts that may contaminate polysomnography recordings, and the necessity to account for all physiological changes throughout the sleep cycles to ensure better data interpretability. Here, we review the field of sleep neuroimaging in healthy non-sleep-deprived populations, from early findings to more recent developments. Additionally, we discuss the challenges of applying concurrent electroencephalography and imaging techniques to sleep, which consequently have impacted the sample size and generalizability of studies, and possible future directions for the field.</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e14462"},"PeriodicalIF":3.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Book Review: \"The Clinician's Guide to Cognitive and Behavioural Therapeutics (CBTx) for Insomnia-A Scientist-Practitioner Approach\".","authors":"Daniel Ruivo Marques","doi":"10.1111/jsr.70016","DOIUrl":"https://doi.org/10.1111/jsr.70016","url":null,"abstract":"","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e70016"},"PeriodicalIF":3.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New developments in insomnia assessment and diagnosis: Self-reported questionnaires, clinical interviews, and ecological momentary assessment.","authors":"Silvia Cerolini, Jason G Ellis, Debora Meneo, Elisabetta Baldi, Chiara Baglioni","doi":"10.1111/jsr.70010","DOIUrl":"https://doi.org/10.1111/jsr.70010","url":null,"abstract":"<p><p>Accurate and timely assessment is essential for diagnostic and therapeutic purposes. Over the past few years, new developments in the assessment of insomnia disorder have been outlined. This review aims to summarise the available instruments in line with the updated scientific research and advances in clinical sleep research. A synthesis of new developments in the field from 2020 to 2024, focussing on self-reported questionnaires, clinical interviews, and ecological momentary assessment, are provided. After exploring novel advances and their interplay with evidence-based validated instruments, we will discuss limitations and future directions. What are we missing? What should be improved and ameliorated? What are the next steps for insomnia assessment and diagnosis regarding methodology, dissemination, and practice?</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e70010"},"PeriodicalIF":3.4,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promoting vocabulary learning during sleep at home using closed-loop targeted memory reactivation.","authors":"Federico Salfi, Aurora D'Atri, Benedetto Arnone, Domenico Corigliano, Giulia Amicucci, Lorenzo Viselli, Federica Naccarato, Fabiana Festucci, Daniela Tempesta, Michele Ferrara","doi":"10.1111/jsr.70000","DOIUrl":"https://doi.org/10.1111/jsr.70000","url":null,"abstract":"<p><p>Targeted memory reactivation represents an established technique for promoting sleep-dependent memory consolidation in laboratory studies. This investigation aimed to test the potentiality of a wearable electroencephalography-based closed-loop targeted memory reactivation system to boost vocabulary learning in home settings. In the evening, 24 adults (23.58 years ± 3.36 years, 19 females) were asked to learn the Italian translation of 40 pseudowords (test session). Subsequently, participants slept at their home wearing an electroencephalography headband (Dreem 2), and half of the pseudowords were acoustically re-presented (cued) following the real-time detection of slow waves. After the awakening, memory recall of the Italian translations was retested. The stimulation effect was evaluated by comparing the test-retest variations in memory accuracy between cued and uncued pseudowords. Moreover, we assessed the event-related potentials and spectral perturbations induced by the cued stimuli during sleep, comparing the electrophysiological correlates of correctly translated pseudowords with incorrectly translated ones at the retest session. Closed-loop targeted memory reactivation increased the translation accuracy for cued pseudowords (+8.6%), while no significant test-retest variation for uncued items was observed (-4.6%). Time-frequency analysis indicated a spectral power increase in the spindle frequency band coinciding with the second positive peak of the sound-elicited slow wave as the correlate of successful morning recall. This study extended the targeted memory reactivation effectiveness in enhancing vocabulary learning to an ecological home environment, providing further support to the role of spindle activity in the targeted memory reactivation effect. A wearable closed-loop targeted memory reactivation system could represent a memory-enhancement tool in real-world settings by promoting the hallmark sleep electroencephalographic rhythms of memory consolidation.</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e70000"},"PeriodicalIF":3.4,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The endothelin-1 system among high-risk pregnant women with obstructive sleep apnea.","authors":"Samantha Shirk, Melissa L Kozakiewicz, Kristin N Sheehan, Kang Rui Xiang, Amit K Saha, David Stamilio, Jie Zhang, Abigail L Koch, Andrew M Namen","doi":"10.1111/jsr.70008","DOIUrl":"https://doi.org/10.1111/jsr.70008","url":null,"abstract":"<p><p>Obstructive sleep apnea is associated with gestational hypertension. Elevated endothelin-1 is a proposed factor in the pathogenesis of gestational hypertension. However, the association between endothelin-1 and obstructive sleep apnea complicating pregnancy is unknown. In a prospective cohort of 60 pregnant patients with obesity but without confounding comorbid conditions (i.e. cardiac/pulmonary disease), plasma and placental samples were collected at delivery in 30 women with obstructive sleep apnea and 30 without. Endothelin-1 concentrations were evaluated using Western blot, quantitative real-time polymerase chain reaction, immunohistochemistry, and enzyme-linked immunosorbent assay. Multivariable analyses were conducted comparing endothelin-1 levels between obstructive sleep apnea and non-obstructive sleep apnea groups. There was no significant difference in band intensity or quantitative densitometric evaluation when comparing obstructive sleep apnea-positive and -negative groups (p = 0.42). mRNA expression of endothelin-1 did not differ in placental tissues between groups (p = 0.73). There was no significant difference in endothelin-1 median plasma concentrations between groups (p = 0.95). However, there was a significant sixfold increase in the rate of endothelin-1 elevation > 90th percentile (adjusted odds ratio 5.9, 95% confidence interval 1.05-32.7) after adjusting for confounding by body mass index. Additionally, lower pre-pregnancy body mass index (< 32 kg m^-2) was associated with plasma endothelin-1 > 11 at delivery (p < 0.01), and class 3 obesity appeared protective for having elevated plasma endothelin-1 > 90th percentile (p = 0.03). Overall, in this prospective cohort of high-risk pregnant patients, obstructive sleep apnea was associated with an increased rate of markedly elevated (> 90th percentile) endothelin-1 plasma levels. Lower pre-pregnancy body mass index among patients with obesity was associated with elevated endothelin-1 plasma levels. Obstructive sleep apnea screening questionnaires focused on high body mass index may result in underestimated risk.</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e70008"},"PeriodicalIF":3.4,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Co-production in sleep research: A scoping review of current practices and future directions.","authors":"Emma Louise Gale, Raahat Manrai, Lorna Caddick, Aja Murray, Heather C Whalley, Daniel Smith, Maria Gardani","doi":"10.1111/jsr.14476","DOIUrl":"https://doi.org/10.1111/jsr.14476","url":null,"abstract":"<p><p>Sleep is essential for mental and physical health, and research in the field has substantially expanded over the past 50 years. Co-production methodology has been increasingly used within health and social care research, and refers to collaboration between researchers, policy makers, community partners and wider stakeholders. The aim of this scoping review was to detail the use of co-production methods within sleep research. A review of the existing literature was conducted using seven databases following PRISMA-ScR guidelines. Search terms included objective and subjective sleep outcomes, and the use of co-production research methodologies. Sixteen studies were included in the final review: 10 studies used solely qualitative co-production methods to inform intervention design and development (sleep as a primary outcome [n = 5] and as a secondary outcome [n = 5]), and six studies used co-production methodologies to establish sleep as a priority outcome for future research. Most studies used consultation approaches to design interventions (n = 8), instead of using co-design teams (n = 2). Two studies focusing on intervention development recruiting participants from clinical populations with poor sleep, other studies recruited from those with other underlying conditions or a healthy population. The most common limitations of the included studies were small sample size, researcher driven topics/domains for the PAR components, under-representative samples and COVID-19 pressures. Future sleep research should consider the use of co-production methodologies from the study conceptualisation, through to the design, development and implementation of research to further benefit the intended research population.</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e14476"},"PeriodicalIF":3.4,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The cathartic dream: Using a large language model to study a new type of functional dream in healthy and clinical populations.","authors":"Lampros Perogamvros, Vincent Rochas, Jean-Baptiste Beau, Virginie Sterpenich, Laurence Bayer","doi":"10.1111/jsr.70001","DOIUrl":"https://doi.org/10.1111/jsr.70001","url":null,"abstract":"<p><p>According to some theories of emotion regulation, dreams could modify negative emotions and ultimately reduce their intensity. We introduce here the idea of cathartic dream, a specific and separate type of emotional dream, which is characterized by a dynamic plot with emotional twists, and where negative emotions are expressed and ultimately decreased. This process would reflect psychological relief (catharsis according to the Aristotelian definition) and fulfil an emotion regulation function. We developed and validated a tool using a large language model to emotionally categorize the different dreams from dream diaries. Based on this tool, we were able to detect the prevalence of cathartic dreams in datasets of both healthy participants and patients with nightmares. Additionally, we observed the increase of cathartic dreams during 2 weeks of imagery rehearsal therapy and targeted memory reactivation during rapid eye movement sleep. We also demonstrate how the increase of cathartic dreams correlates significantly with the decrease of depression scores in patients with nightmares under therapy, thus supporting their likely functional role in well-being and their distinct nature among other emotional dreams.</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e70001"},"PeriodicalIF":3.4,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A cross-sectional study of the association between sleep disturbance profiles, unmet mental health or substance use needs, and presenteeism among United States activity-duty service members using the 2018 health-related behaviours survey (HRBS).","authors":"Teresa L Russell, Darrell E Singer, J Kent Werner, James D Mancuso, Anwar E Ahmed","doi":"10.1111/jsr.14477","DOIUrl":"https://doi.org/10.1111/jsr.14477","url":null,"abstract":"<p><p>Inadequate sleep, unmet mental health or substance use needs (unmet needs), and presenteeism are prevalent among military populations. This study aimed to cross-sectionally determine the association between sleep disturbance profiles, unmet needs, and presenteeism in US active-duty service members, both separately and combined. Data were collected from the 2018 Health-Related Behaviours Survey. The response rate was 9.6%. Presenteeism was collected as the number of days (0-30) then collapsed for analysis. Latent class analysis (LCA) was used to classify service members into sleep disturbance profiles. Odds ratios and confidence intervals (CIs) were estimated by binary and ordinal logistic models. Approximately 21% of the 17,166 service members reported at least one presentee day (95% CI: 19.8%-21.8%). Persistent presenteeism was 13.6% (95% CI: 12.7-14.4%). Four sleep disturbance profiles were identified by LCA: (1) high sleep disturbance (reported in 22.5%), (2) short sleep duration (26%), (3) trouble sleeping (6.9%), and (4) none to slight sleep disturbance (reference, 44.6%). Female sex, being separated/divorced/widowed, short sleep duration, trouble sleeping, high sleep disturbance, unmet needs, and both unmet needs and inadequate sleep together were associated with higher odds of high presenteeism levels and persistent presenteeism. Bachelor's or higher educated, 25-34-year-old, Hispanic/Latinx, Officer, Air Force, and Coast Guard service members were associated with lower odds of high presenteeism levels and persistent presenteeism. Despite the decreasing trends between 2015 and 2018, the high prevalence of presenteeism presents a significant burden on work productivity and readiness that behavioural modification may alter.</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e14477"},"PeriodicalIF":3.4,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive and psychological factors associated with treatment response in ACT-I and CBT-I for insomnia.","authors":"Ila Marques Porto Linares, Susanna Jernelöv, Renatha El Rafihi-Ferreira","doi":"10.1111/jsr.14473","DOIUrl":"https://doi.org/10.1111/jsr.14473","url":null,"abstract":"<p><p>Cognitive behavioural therapy for insomnia is the treatment of choice for patients with insomnia, but not all patients benefit, and novel psychological treatment approaches have emerged (e.g. acceptance and commitment therapy). Thus, the aim of the present study was to evaluate whether treatment modality, adherence, insomnia severity, anxiety, depression, beliefs about sleep or acceptance of sleep problems are factors associated with response to psychological insomnia treatment. The sample consisted of 152 adults (115 women; mean age = 40.6 years, SD = 10.2) with chronic insomnia, and they participated in a randomized clinical trial comparing acceptance and commitment therapy for insomnia (as a standalone) with cognitive behavioural therapy for insomnia. The outcome measure was proportion of treatment responders (8 points reduction or more) on the Insomnia Severity Index, assessed at pre- and post-treatment and 6-month follow-up. The predictor variables were assessed at pre-treatment. The final multivariate model showed that undergoing cognitive behavioural therapy for insomnia increased the chances of treatment response at post-treatment by 2.70 times when compared with acceptance and commitment therapy for insomnia (odds ratio = 2.70 [1.14-6.38]). In addition, each additional point in pre-treatment insomnia severity (odds ratio = 1.15 [1.01-1.30]) and dysfunctional beliefs about sleep (odds ratio = 1.02 [1.00-1.05]) scores increased the chances of response at post-treatment. Treatment adherence increased the chances of treatment response at post-treatment by 3.07 times (odds ratio = 3.07 [1.28-7.34]). Finally, each additional point on the Insomnia Severity Index pre-treatment increased the chances of treatment response at the 6-month follow-up (odds ratio = 1.14 [1.01-1.29]). In conclusion, cognitive behavioural therapy for insomnia increases the chance of treatment response compared with acceptance and commitment therapy for insomnia. Moreover, higher adherence, insomnia severity and dysfunctional beliefs about sleep predict treatment outcome in both treatments.</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e14473"},"PeriodicalIF":3.4,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of current digital cognitive behavioural therapy for insomnia interventions for adolescents with insomnia symptoms: A systematic review and meta-analysis.","authors":"Melissa A Cleary, Cele Richardson, Ruby J Ross, Helen S Heussler, Andrew Wilson, Jenny Downs, Jennifer Walsh","doi":"10.1111/jsr.14466","DOIUrl":"https://doi.org/10.1111/jsr.14466","url":null,"abstract":"<p><p>Sleep problems occur in up to 20%-45% of adolescents. This systematic review and meta-analysis examined the effectiveness of digital sleep interventions, based on cognitive behavioural therapy for insomnia, for adolescents with insomnia symptoms. The objective was to synthesise and quantify, through meta-analyses, changes in sleep following completion of a digital sleep-based intervention. MEDLINE, PubMed, PsycINFO, Scopus, EMBASE, CENTRAL, and Web of Science databases were searched from January 2012 to March 2024. Within-subject studies or randomized-controlled trials reporting the effects of digital cognitive behavioural therapy for insomnia were included. Risk of bias was assessed using the integrated quality criteria for the review of multiple study designs. Random-effects meta-analyses estimated pooled standardised within-subject mean differences to assess effectiveness. Nine studies involving 486 adolescents were included. Digital cognitive behavioural therapy for insomnia interventions were effective in reducing insomnia symptoms (Hedges' g = 1.40), subjective sleep-onset latency (Hedges' g = 0.72) and waking after sleep onset (Hedges' g = 0.47), and increasing subjective and objective total sleep time (Hedges' g = -0.29 and -0.23, respectively). Other objective measures of sleep did not improve. All studies met the minimum ICROMS score and were considered to be of sufficient quality. Seven within-subject studies failed to satisfy all mandatory criteria. These results suggest that digital cognitive behavioural therapy for insomnia interventions are effective in improving adolescent's perceptions of their sleep, but are less effective at improving some objective measures of sleep. To achieve a clear understanding of how digital cognitive behavioural therapy for insomnia interventions compare with other behavioural interventions, additional high-quality randomized-controlled trials comparing digital cognitive behavioural therapy for insomnia interventions with traditional in-person modalities are needed. (PROSPERO;CRD42021287479).</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e14466"},"PeriodicalIF":3.4,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}