Journal of Sleep Research最新文献

{"title":"Nightly Sleep Disruption Predicts Next-Day PTSD Symptoms: A Pilot Ecological Momentary Assessment Study in Sexual Assault Survivors With and Without PTSD.","authors":"Rebecca C Cox, Bunmi O Olatunji","doi":"10.1111/jsr.70361","DOIUrl":"10.1111/jsr.70361","url":null,"abstract":"<p><p>Sleep disruption is a hallmark feature of posttraumatic stress disorder (PTSD). Studies using ecological momentary assessment suggest sleep disruption predicts next-day PTSD symptoms, though evidence for the reverse effect is inconsistent. We examined bidirectional associations between subjective sleep and PTSD symptom severity in a pilot sample of sexual assault survivors with and without PTSD (N = 35). Participants completed a sleep diary each morning and self-report measures of PTSD symptom severity and negative affect 3 times/day for 1 week. Multilevel models revealed that shorter sleep duration and longer sleep onset latency significantly predicted higher PTSD symptoms the following day, controlling for prior PTSD symptoms and negative affect (p's < 0.05). In contrast, tests of reverse models revealed no significant associations between daytime PTSD symptoms and subsequent sleep disruption on any sleep outcome (p's > 0.05). These findings suggest night-to-night disruptions in sleep may signal risk for increased PTSD symptoms. Implications for targeting sleep to treat PTSD symptoms are discussed.</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e70361"},"PeriodicalIF":4.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13232708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148015648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood Pressure Trajectories and Cardiovascular Risk in Obstructive Sleep Apnea: A Dual-Cohort Analysis.","authors":"Jianhong Liao, Yunhan Shi, Bowen Zhang, Mengshuang Lv, Yanru Li, Demin Han","doi":"10.1111/jsr.70366","DOIUrl":"10.1111/jsr.70366","url":null,"abstract":"<p><p>This study primarily examined longitudinal systolic blood pressure trajectories in untreated obstructive sleep apnea (OSA) and their association with cardiovascular risk. A complementary analysis in the independent trial evaluated longitudinal blood pressure change after CPAP treatment. Data were obtained from the observational Sleep Heart Health Study (SHHS) and the interventional Apnea Positive Pressure Long-term Efficacy Study (APPLES). Participants with OSA who were not receiving antihypertensive treatment were included. Group-based trajectory modelling was used to identify SBP patterns over time, cardiovascular risk was assessed using Kaplan-Meier and Cox proportional hazards analyses, and CPAP-related SBP changes were evaluated using linear mixed-effects models. During a 10-year follow-up of 624 untreated patients with OSA, three SBP trajectories were identified: stable (87.0%), falling (5.9%), and rising (7.1%). Compared with the stable trajectory, the rising SBP group had a significantly higher risk of cardiovascular events (adjusted hazard ratio [HR] 2.84, 95% confidence interval [CI] 2.13-3.78; p < 0.001). CPAP therapy was associated with a reduced risk of cardiovascular events (adjusted HR 0.62, 95% CI 0.45-0.84; p = 0.002). Supplementary adherence analyses suggested more sustained SBP reduction with higher nightly CPAP use, and restricted cubic spline analysis indicated a steeper decline above 5.59 h/night. These findings suggest that rising SBP trajectories identify patients with OSA at highest cardiovascular risk, while CPAP use was associated with lower cardiovascular event risk in the observational SHHS comparison and modest SBP reduction in the complementary APPLES analysis. Trial Registration: SHHS (NCT00005275) and APPLES (NCT00051363).</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e70366"},"PeriodicalIF":4.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148138449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep Improvement for Metabolic Health: A Feasibility Trial of a Digital Sleep Treatment in People With Insomnia and Non-Diabetic Hyperglycaemia.","authors":"Rachel Sharman, David Ray, Andrew Farmer, Poppy C E Green, Victoria Harris, Fredrik Karpe, Colin A Espie, Diana Mantripp, Thomas Marjot, Niall M McGowan, Jeremy W Tomlinson, Simon D Kyle","doi":"10.1111/jsr.70306","DOIUrl":"10.1111/jsr.70306","url":null,"abstract":"<p><p>Insomnia may play a causal role in type 2 diabetes (T2D). Addressing insomnia through cognitive behavioural therapy (CBTi) in people with non-diabetic hyperglycaemia could potentially reduce the risk of progression to T2D. To inform a future randomised trial, we performed a feasibility study of digital CBT (dCBTi) in individuals at increased risk of T2D. Participants were identified from 10 primary care practices in the UK and given access to dCBTi. Outcomes were evaluated at baseline (Week-0) and post-treatment (Week-11). Primary feasibility outcomes were ability to recruit and treatment engagement. We also quantified within-group mean change (95% CI) in insomnia severity (Insomnia Severity Index), health-related quality of life (EQ-5D-3L), depression (Center for Epidemiologic Studies Depression Scale), chronotype (reduced Morningness-Eveningness Questionnaire), sleep (7-day actigraphy and diary), continuous glucose monitoring (7-days) and fasting blood metabolites (insulin, lipids, glucose and C-reactive protein). The recruitment target was 20. Of 242 people completing screening, 36 were eligible and 24 were enrolled (age 65.5 ± 12.4 years, 70.8% female). Twenty-three (96%) completed post-intervention assessments. Treatment engagement was excellent (83.3% completed ≥ 4 sessions). The intervention was associated with a large reduction in insomnia severity [-4.7 (95% CI: -6.2 to -3.2), d = -1.4] and medium reduction in depressive symptoms [-2.7 (95% CI: -5.1 to -0.2), d = -0.5]. Sleep diary parameters tended to show greater improvement following intervention relative to actigraphy. There was evidence of a reduction in serum lactate, glycerol and triglycerides but no clear change in glucose or insulin. Results suggest a full trial is likely feasible and that people with NDH find the intervention acceptable and beneficial. Trial Registration: This trial was prospectively registered on the UKs clinical study registry, the ISRCTN (ISRCTN19682964, https://doi.org/10.1186/ISRCTN19682964).</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e70306"},"PeriodicalIF":4.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13619033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thoracoabdominal Asynchrony in Healthy Children.","authors":"Kristjan Dereksson, Sigrun Helga Lund, Agneta Markström, Sigridur Sigurdardottir, Erna Sif Arnardottir, Michael V Clausen, Sigurveig T Sigurdardottir, Tryggvi Helgason, Erik A Eklund","doi":"10.1111/jsr.70394","DOIUrl":"10.1111/jsr.70394","url":null,"abstract":"<p><p>Measuring asynchrony between the thorax and abdomen during sleep provides information about inspiratory effort and upper airway obstruction in children, aiding in the diagnosis of obstructive sleep apnea (OSA). This study aimed to define a normative range for thoracoabdominal asynchrony (TAA) in healthy children by studying polysomnographies of 113 children aged 10-13 years. The percentage of total sleep time (TST) spent with elevated TAA, > 40°, was measured, as well as obstructive apnea-hypopnea index (OAHI), sleep position, sleep stage and snoring. Subjects without measurable OSA (N = 94) were defined as healthy subjects and they had elevated TAA for an average of 3.3% of their TST while subjects with OSA (N = 19) had elevated TAA for 10.7% of their TST (p < 0.00001). The cut-off point for the normal prevalence of elevated TAA was estimated at 9.6% of TST, which can be rounded up to 10% for ease of use. TAA prevalence rose in REM-sleep and in the supine position and was related to increased snoring. Children with obesity had higher OAHI, more prevalent TAA and more snoring. No gender differences were observed. Parent-reported PSQ scores showed limited concordance with objective measures. TAA assessment, available from standard RIP-bands placed around chest and abdomen, may aid in the interpretation of sleep studies in children, both home sleep apnea tests and polysomnographies. With further research, they might help guide clinical decision making in paediatric sleep medicine.</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e70394"},"PeriodicalIF":4.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13619078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148272000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Properties of the PROMIS Pediatric Sleep Disturbance and Sleep-Related Impairment Self and Proxy Short Forms in Early Adolescents With and Without ADHD.","authors":"Stephen P Becker, Melissa C Miller, G Leonard Burns","doi":"10.1111/jsr.70381","DOIUrl":"10.1111/jsr.70381","url":null,"abstract":"<p><p>This study evaluated the psychometric properties and psychopathology correlates of the Patient-Reported Outcome Measurement Information System (PROMIS) Pediatric Sleep Disturbance and Sleep-related Impairment Self and Proxy Short Forms in early adolescents with and without attention-deficit/hyperactivity disorder (ADHD). Participants were 341 early adolescents (ages 10-12 years; 52.2% female), with approximately half meeting diagnostic criteria for ADHD. Adolescents and their caregivers completed short form versions of the PROMIS Pediatric Sleep Disturbance and Sleep-related Impairment Self and Proxy Forms, in addition to measures of ADHD, anxiety, and depressive symptoms. Adolescents with ADHD were significantly more likely to be taking melatonin (33.7%) compared to adolescents without ADHD (14.9%). Across informants, the PROMIS paediatric sleep measures demonstrated strong internal consistency, moderate convergent validity, and partial evidence of discriminant validity. As expected, adolescents with ADHD had higher scores in both sleep disturbance and sleep-related impairment than their non-ADHD peers across both informants, and most differences remained when participants taking stimulant medications were excluded from analyses. No sex differences in either sleep disturbance or sleep-related impairment scores were present across either adolescent or parent informant. Both sleep disturbance and sleep-related impairment were consistently associated with higher levels of psychopathology across parent, teacher, and adolescent reports, with daytime impairment showing particularly strong and unique associations with depression. This study provides psychometric support for the PROMIS Pediatric Sleep Disturbance and Sleep-related Impairment Self and Proxy Short Forms in early adolescents, including youth with ADHD who frequently experience sleep disturbances and sleep-related impairment.</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e70381"},"PeriodicalIF":4.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13619014/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148143723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Pain Intensity Associated With Sleep-Spindle Activity in Persons With Chronic Spinal Pain and Chronic Insomnia Disorder? A Polysomnography Study.","authors":"Nils Runge, Nyissa Walsh, Thien Thanh Dang-Vu, Liesbet De Baets, Céline Labie, Thomas Bilterys, Sabine Verschueren, Dieter Van Assche, Jo Nijs, Anneleen Malfliet, Lieven Danneels, Kelly Ickmans, Maarten Moens, Dorien Goubert, Olivier Mairesse, Arsenio Paez","doi":"10.1111/jsr.70368","DOIUrl":"10.1111/jsr.70368","url":null,"abstract":"<p><p>Chronic spinal pain is associated with fragmented sleep, yet the neurophysiological mechanisms linking the two remain unclear. Given their role in sensory gating and sleep stability, sleep spindles may represent a key mechanism connecting chronic spinal pain and sleep fragmentation. This study examined whether pain intensity over the past 4 weeks was associated with sleep spindle density and related characteristics in individuals with chronic low back or neck pain and chronic insomnia disorder. Data from 120 participants, classified by self-reported pain severity (mild, moderate, severe), were compared on spindle density derived from C4-A1A2 and F4-A1A2 EEG channels. No significant group differences were found in spindle density (respectively, C4: p = 0.372 and F4: p = 0.744). Regression analyses adjusted for age, sex and medication use showed that pain intensity did not significantly predict spindle density (p > 0.05). However, exploratory regression models revealed small but statistically significant associations between pain intensity and both spindle power (p = 0.047) and amplitude (p = 0.038) on the C4 channel. These findings suggest that while spindle density does not vary meaningfully with pain intensity in this clinical population, alterations in spindle power and amplitude may reflect pain-related modulation of thalamocortical activity. This highlights the complexity of pain-sleep interactions in the presence of chronic spinal pain and insomnia. More nuanced, temporally resolved assessments of pain are needed to clarify the dynamic interactions between chronic pain, insomnia, and sleep microarchitecture.</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e70368"},"PeriodicalIF":4.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148015983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Restorative Sleep Gaps and Occupational Fatigue in the US Navy.","authors":"Dale W Russell, Patrick J Rosopa","doi":"10.1111/jsr.70385","DOIUrl":"10.1111/jsr.70385","url":null,"abstract":"<p><p>Sustained military and maritime operations demand continuous cognitive control and teamwork under conditions that restrict sleep opportunity and recovery. Nutritional constraints may further shape perceived recovery and functioning in these settings. This study examined relationships among hunger, diet quality, sleep, health, anxiety, burnout, command satisfaction and mishap risk among 9742 enlisted active-duty US Navy sailors across 155 ships. For Aim 1, guided by the Job Demands-Resources and Conservation of Resources frameworks, structural equation modelling evaluated whether hunger and the restorative sleep gap (sleep needed to feel well-rested minus sleep obtained while underway) are associated with downstream health and operational outcomes. Aim 2 evaluated whether fatigue-related outcomes were more strongly differentiated by occupational role than by department. Increased hunger and larger sleep gaps were associated with poorer sleep quality, greater anxiety, higher burnout and reduced command satisfaction, even after controlling for demographic and shipboard factors. Occupational differences were generally larger than departmental differences for multiple fatigue and health-related outcomes, underscoring that fatigue vulnerability is shaped by specific work roles in addition to broad organizational divisions. Findings highlight the need for targeted fatigue-risk management and attention to sleep and nutrition access within operational environments.</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e70385"},"PeriodicalIF":4.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148252046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19-Induced Narcolepsy Type I With Cataplexy: A Short Report.","authors":"Torsten Vinding Merinder, Martin Langeskov-Christensen, Filip Kirov","doi":"10.1111/jsr.70372","DOIUrl":"10.1111/jsr.70372","url":null,"abstract":"<p><p>Narcolepsy type I is a rare neurological sleep disorder characterised by chronic excessive daytime sleepiness, cataplexy, and low orexin (hypocretin) levels. Infection with SARS-CoV-2 has been linked to neurological and neuropsychiatric sequelae, but cases of post-COVID narcolepsy remain extremely uncommon. We report a previously healthy 42-year-old Caucasian female who developed excessive daytime sleepiness, cataplexy, and hypnagogic/hypnopompic hallucinations within 3 months of confirmed SARS-CoV-2 infection. Polysomnography (PSG) showed disturbed nocturnal sleep with a high arousal index and periodic limb movements and mild sleep apnea, while the multiple sleep latency test (MSLT) showed a mean latency of 1 min with sleep-onset rapid eye movement (REM) periods in all naps. Cerebrospinal fluid hypocretin was markedly reduced (< 40 ng/L), confirming narcolepsy type I. Following the diagnosis, medical treatment was initiated-with methylphenidate for hypersomnolence followed by venlafaxine for cataplexy, which led to a substantial symptomatic improvement, enabling a return to daily functioning. The case contributes to the minimal literature on narcolepsy following COVID-19 and supports hypotheses of autoimmune-mediated destruction of hypocretin-producing neurons triggered by viral infection. Clinicians should maintain a high index of suspicion for primary sleep disorders in patients with persistent fatigue and hypersomnolence after COVID-19, as early recognition and targeted treatment markedly improve outcomes.</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e70372"},"PeriodicalIF":4.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13619020/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148055213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacotherapy for Precision Medicine of Obstructive Sleep Apnea.","authors":"Wenxin Bao, Rong Ren, Shuancheng Ren, Xiangdong Tang, Ye Zhang","doi":"10.1111/jsr.70379","DOIUrl":"10.1111/jsr.70379","url":null,"abstract":"","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e70379"},"PeriodicalIF":4.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148015785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep Health of Athletes of Different Sports: Translation and Validation of the Athlete Sleep Screening Questionnaire to Portuguese.","authors":"João Barreira, Júlio A Costa, João Brito, Vasco Cardoso, Cátia Reis","doi":"10.1111/jsr.70349","DOIUrl":"10.1111/jsr.70349","url":null,"abstract":"<p><p>This study aimed to translate and validate the Athlete Sleep Screening Questionnaire (ASSQ) into Portuguese and assess the sleep health of athletes using the ASSQ. Translation followed established scientific guidelines. A sample of 246 Portuguese athletes from various sports completed the ASSQ, the Pittsburgh Sleep Quality Index (PSQI) and the Reduced Morningness-Eveningness Questionnaire (r-MEQ). Exploratory and confirmatory factor analysis supported two factors for the Sleep Difficulty Score (SDS) and chronotype subscales. Model fit indices indicated excellent fit for SDS and chronotype. Internal consistency was acceptable for SDS (α = 0.58) and chronotype (α = 0.54). Mean SDS was 5.7, and 22% of the sample were found to have sleep problems. Specifically, 16% were classified with moderate sleep problems and 6% with severe sleep problems. No significant differences in SDS categories were found across sex, sports type, sports environment, competitive level or age group. Travel-related sleep disturbances were reported by 20% of athletes, and 11% experienced performance issues after travelling. Chronotype differed by sports type, sports environment, competitive level and age group, but not by SDS categories. Additionally, morning chronotypes reported more travel-related sleep disturbances (p = 0.045). The Portuguese ASSQ showed strong validity and acceptable reliability. Cohort analysis revealed that a substantial proportion of Portuguese athletes reported having sleep problems and some would benefit from specific interventions intended to improve sleep.</p>","PeriodicalId":17057,"journal":{"name":"Journal of Sleep Research","volume":" ","pages":"e70349"},"PeriodicalIF":4.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13619028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147868909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}