Yao Xiao , Sri Kandala , Jenny Huang , Jinyuan Liu , Trey McGonigle , Deanna Barch , Yangqing Tang , Guoguang Fan , Fei Wang , Fay Y. Womer
{"title":"The involvement of the cerebellar vermis across the psychotic-affective spectrum in enriched samples of recent-onset schizophrenia, bipolar disorder, and major depressive disorder","authors":"Yao Xiao , Sri Kandala , Jenny Huang , Jinyuan Liu , Trey McGonigle , Deanna Barch , Yangqing Tang , Guoguang Fan , Fei Wang , Fay Y. Womer","doi":"10.1016/j.jpsychires.2024.11.023","DOIUrl":"10.1016/j.jpsychires.2024.11.023","url":null,"abstract":"<div><h3>Background</h3><div>The cerebellar vermis is implicated in cognition and emotion, two key components of the psychotic-affective spectrum that includes schizophrenia (SCZ), bipolar disorder (BD), and major depressive disorder (MDD).</div></div><div><h3>Methods</h3><div>Volumes [N = 391; 97 SCZ, 78 BD, 103 MDD, and 113 healthy controls (HC)] and seed-to-whole brain functional connectivity (FC) [N = 136; 33 SCZ, 23 BD, 51 MDD, and 29 HC] of total vermis and its subregions, V1 (anterior), V2 (posterior superior), and V3 (posterior inferior), were examined across SCZ, BD, MDD, and HC in samples enriched for first episode individuals. The relationship between vermis volumes and FC and cognitive measures were explored.</div></div><div><h3>Results</h3><div>Significant diagnosis (p = 0.05) and diagnosis by subregion (p = 0.02) effects on vermis volumes were observed across the four groups, particularly in V2 (p = 0.01) with decreased V2 volumes in SCZ compared to BD (p<sub>FDR</sub> = 0.01). SCZ, BD, and MDD had significant effects on vermis FC, with SCZ having the greatest effects. SCZ had effects on FC of V1, V2, and V3 with broadly distributed cortical and subcortical regions, while BD and MDD effects were observed in FC of V2 and V3 with frontotemporal regions. Exploratory analyses found significant canonical correlation between V3 FC and WM and visual learning for SCZ and MDD. No significant associations were shown between vermis volumes and cognitive measures.</div></div><div><h3>Conclusions</h3><div>Structural and functional alterations of the vermis appear to vary across the psychotic-affective spectrum of SCZ, BD, and MDD. Posterior vermis may be a key neural intersection between affective and psychotic psychopathology.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"181 ","pages":"Pages 14-22"},"PeriodicalIF":3.7,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of precarious employment with depressive symptoms and insomnia: Findings from the Korean Working Conditions Survey","authors":"Seong-Uk Baek , Jin-Ha Yoon","doi":"10.1016/j.jpsychires.2024.11.021","DOIUrl":"10.1016/j.jpsychires.2024.11.021","url":null,"abstract":"<div><div>Precarious employment (PE) is an important occupational health concern. This study aims to examine the relations between PE and depressive symptoms and insomnia in Korean workers. This study included a nationally representative sample of 49,420 adult workers. A modified version of the Employment Precariousness Scale (EPRES), which comprises six dimensions (temporariness, disempowerment, vulnerability, exercise of rights, uncertain work schedules, and wages), was used to quantify PE levels on a scale ranging from 0 to 100. PE levels were categorized into four groups based on quartile values. Depressive symptoms were assessed using the World Health Organization-5 Well-Being Index, and insomnia was assessed using the Minimal Insomnia Symptom Scale. Logistic regressions were performed, and odds ratios (ORs) and 95% confidence intervals (CIs) were estimated. The prevalence rates of depressive symptoms and insomnia were 10.7% and 8.4%, respectively. Compared with the lowest PE level, the highest PE levels were associated with both depressive symptoms (OR: 2.86, 95% CI: 2.61–3.14) and insomnia (OR: 1.33, 95% CI: 1.21–1.47). An interquartile range increase in the EPRES score was associated with a 1.84-fold (95% CI: 1.76–1.92) and 1.23-fold (95% CI: 1.17–1.29) increase in the odds of depressive symptoms and insomnia, respectively. All six individual dimensions were positively associated with depressive symptoms, whereas three dimensions—vulnerability, uncertain work schedules, and wages—were associated with insomnia. PE is a risk factor for depressive symptoms and insomnia. Policy interventions are required to safeguard mental health of precarious workers.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"181 ","pages":"Pages 7-13"},"PeriodicalIF":3.7,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kyle J. Bourassa , Paul A. Dennis , Pujan Patel , Xue J. Qin , David A. Sbarra , Elizabeth R. Hauser , Allison E. Ashley-Koch , Million Veteran Program , Jean C. Beckham , Nathan A. Kimbrel
{"title":"Social connection and suicidal thoughts and behaviors in the Million Veteran Program cohort","authors":"Kyle J. Bourassa , Paul A. Dennis , Pujan Patel , Xue J. Qin , David A. Sbarra , Elizabeth R. Hauser , Allison E. Ashley-Koch , Million Veteran Program , Jean C. Beckham , Nathan A. Kimbrel","doi":"10.1016/j.jpsychires.2024.11.008","DOIUrl":"10.1016/j.jpsychires.2024.11.008","url":null,"abstract":"<div><div>People with lower levels of social connection are at increased risk for suicidal thoughts and behaviors. This extends to populations at greater risk of death by suicide, including U.S. military veterans. Despite this well-established association, it is unclear which measures of social connection are most useful in identifying veterans who could benefit from intervention to prevent suicide. To this end, we used data from the Million Veteran Program (MVP) to investigate the measures of social connection most strongly associated with suicidal thoughts and behaviors. Our sample included 264,626 veterans who reported on three measures of social connection—marital status, household size, and perceived social support—and were assessed for suicidal thoughts and behaviors using electronic health records. Veterans who were partnered (<em>OR</em> = 0.78, 95% CI [0.76–0.80], <em>p</em> < .001), living with others (<em>OR</em> = 0.71, 95% CI [0.70–0.73], <em>p</em> < .001), or reported higher levels of social support (<em>OR</em> = 0.67, 95% CI [0.65–0.69], <em>p</em> < .001), were less likely to have suicidal thoughts and behaviors. These associations varied by veterans’ age, sex, and era of military service. When combined into a single risk score, lower levels of social connection were associated with greater likelihood of suicidal thoughts and behaviors (β = 1.42, 95% CI [1.40–1.43], <em>p</em> < .001). Social support, particularly positive social interactions, showed the strongest associations with suicidal thoughts and behaviors in elastic net regression models. Common measures of social connection, particularly social support, could be useful in assessing suicide risk and treatment needs for veterans.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"180 ","pages":"Pages 500-505"},"PeriodicalIF":3.7,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142643794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria R. Dauvermann , Laura Costello , Leila Nabulsi , Genevieve Mc Philemy , Emma Corley , Andrea Fernandes , Pramath Kakodkar , Wee Xuan Neo , David Mothersill , Laurena Holleran , Brian Hallahan , Colm McDonald , Gary Donohoe , Dara M. Cannon
{"title":"Structural brain connectivity does not associate with childhood trauma in individuals with schizophrenia","authors":"Maria R. Dauvermann , Laura Costello , Leila Nabulsi , Genevieve Mc Philemy , Emma Corley , Andrea Fernandes , Pramath Kakodkar , Wee Xuan Neo , David Mothersill , Laurena Holleran , Brian Hallahan , Colm McDonald , Gary Donohoe , Dara M. Cannon","doi":"10.1016/j.jpsychires.2024.10.030","DOIUrl":"10.1016/j.jpsychires.2024.10.030","url":null,"abstract":"<div><h3>Background</h3><div>Schizophrenia is a brain dysconnectivity disorder. However, it is not well understood whether the experience of childhood trauma (CT) affects dysconnectivity in individuals with schizophrenia (SZ). Using a network-based approach, we examined whether self-reported CT would explain additional variance compared to whole-brain topology and structural connectivity changes in SZ versus healthy controls (HC).</div></div><div><h3>Material and methods</h3><div>CT was assessed in 51 SZ (mean age ± standard deviation 44 ± 11 years) and 140 HC (34.0 ± 12 years). Structural brain networks were constructed from T1-weighted MR and diffusion-MRI scans using non-tensor based tractography. Group differences in whole-brain topology and permutation-based statistics were examined and corrected for age and sex.</div></div><div><h3>Results</h3><div>SZ showed reductions in efficiency, strength, clustering and density (p < 0.01) as well as increases in path length (F<sub>(range)</sub> = 4.71–18.1, p < 0.03) when compared to HC. We also observed hypoconnectivity in a subnetwork of frontotemporal, frontoparietal and occipital regions in SZ relative to HC (T > 4.0, p < 0.001). However, we did not find that high CT levels were related to structural network differences or structural connectivity changes in SZ.</div></div><div><h3>Conclusions</h3><div>CT did not impact on topology or subnetwork connectivity changes in SZ. High CT levels were also not associated with any differences in network organisation irrespective of diagnosis. However, our findings confirm that SZ showed both network-level reductions and increases in a subnetwork. These findings suggest that the patterns of neuroanatomical dysconnectivity in established schizophrenia may not be influenced by CT. Future studies are needed to investigate the association between CT and structural dysconnectivity in schizophrenia.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"180 ","pages":"Pages 451-461"},"PeriodicalIF":3.7,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Associations of sleep quality with war-related anxiety, childhood stressors, and war-related stressors in a sample of adult Israeli civilians during the Hamas-Israel war","authors":"Ami Cohen , Iris Haimov , Ohad Szepsenwol","doi":"10.1016/j.jpsychires.2024.11.003","DOIUrl":"10.1016/j.jpsychires.2024.11.003","url":null,"abstract":"<div><div>The current study examined the sleep quality of Israeli adults following the onset of the Hamas-Israel war, and the associations of reduced sleep quality with the magnitude of war-related anxiety and exposure to adverse war-related events. We also examined whether exposure to stressors during childhood predicts a greater war-related reduction in sleep quality. 536 Israeli adults (mean age 31.4, 209 women) completed an online survey in January 2024, three months into the war. The survey included questionnaires assessing retrospectively childhood harshness (exposure to morbidity and mortality and low socioeconomic status), adverse childhood experiences, and childhood unpredictability. War anxiety was assessed via the war anxiety scale. The participants also completed the Pittsburgh Sleep Quality Index and the Insomnia Severity Index concerning two time points: (a) retrospectively, before the war, and (b) currently, during the war. Participants reported reduced sleep quality and increased symptoms of insomnia during the war. The magnitude of these changes was predicted by exposure to adverse war experiences both directly and indirectly through war-related anxiety. Poorer sleep quality and increased symptoms of insomnia were also indirectly predicted by childhood exposure to morbidity-mortality of close others and childhood unpredictability through greater war-related anxiety. Thus, exposure to the adverse experiences of war, as well as harsh and unpredictable childhoods, could hinder sleep quality during wartime, with these effects mediated by war-related anxiety.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"180 ","pages":"Pages 394-401"},"PeriodicalIF":3.7,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jaclyn E. Welch , Wenjing Luo , Kyasha J. Ambroise , Yujung N. Choi , Katherine G. Jones , Angelique de Rouen , Sarah K. Fineberg
{"title":"Tell Me about yourself: Analyzing self-referential language use in borderline personality disorder","authors":"Jaclyn E. Welch , Wenjing Luo , Kyasha J. Ambroise , Yujung N. Choi , Katherine G. Jones , Angelique de Rouen , Sarah K. Fineberg","doi":"10.1016/j.jpsychires.2024.11.011","DOIUrl":"10.1016/j.jpsychires.2024.11.011","url":null,"abstract":"<div><div>Depression and some other illnesses are associated with increased self-reference and negative emotion in language. Research findings on lexical patterns in Borderline Personality Disorder (BPD) have been inconsistent. We conducted two studies to evaluate lexical markers of distress in BPD: First compared to healthy controls (HC), and later compared to Post-Traumatic stress disorder (PTSD) patients and trauma-exposed controls (TC).</div><div>Study 1 compared language use in BPD (n = 23) to HC (n = 22). Study 2 featured a new sample comprised of 4 subgroups: BPD (n = 26), Post-Traumatic Stress Disorder (PTSD; n = 17), comorbid BPD + PTSD (n = 22), and one non-psychiatric trauma control group (TC; n = 29). All participants responded to a standardized prompt from an interviewer and language was analyzed using Linguistic Inquiry Word Count (LIWC) software to assess for self-referential language, negative emotion words, and physical words, as well as several other language signatures of interest.</div><div>No consistent significant between-group differences were found for LIWC categories of self-reference, negative emotion, or physical words, though negative tone words were significantly more frequent in BPD than non-psychiatric controls in both studies. There were also no consistent differences in sample length (either talking time or word count) or social measures across studies.</div><div>These data suggest that there are fewer lexical markers of distress in BPD language samples compared to previously reported depression and physical illness samples. Future work using longitudinal approaches to define changes in emotional and cognitive states will be important to clarify the disorder- and state-specificity of lexical markers.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"180 ","pages":"Pages 428-438"},"PeriodicalIF":3.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhenni Wang , Chen Zhang , Qihui Guo , Qing Fan , Lihui Wang
{"title":"Concurrent oculomotor hyperactivity and deficient anti-saccade performance in obsessive-compulsive disorder","authors":"Zhenni Wang , Chen Zhang , Qihui Guo , Qing Fan , Lihui Wang","doi":"10.1016/j.jpsychires.2024.11.013","DOIUrl":"10.1016/j.jpsychires.2024.11.013","url":null,"abstract":"<div><div>Existing studies mainly focused on the inhibition of the task-interfering response to understand the inhibitory deficits of obsessive-compulsive disorder (OCD). However, recent studies suggested that inhibitory function is broadly involved in response preparation and implementation. It is yet unknown if the inhibition dysfunction in OCD extends beyond the task-interfering response to the general inhibitory function. Here we address this issue based on the multidimensional eye-movement measurements, which can better capture the inhibitory deficits than manual responses. Thirty-one OCD patients and 32 healthy controls (HCs) completed the anti-saccade task where multidimensional eye-movement features were developed. Confirmatory factor analysis (CFA) suggested two components of inhibitory function that negatively correlated with each other: one component of oculomotor hyperactivity in generating oculomotor output which is characterized with early premature saccades, early cross rates and saccade number; the other component of task-specific oculomotor efficiency which is characterized with task accuracy, saccade latency, correction rate, and amplitude gain. Importantly, OCD showed both stronger oculomotor hyperactivity and deficient oculomotor efficiency than HCs, and the machine-learning-based classifications showed that the features of oculomotor hyperactivity had higher prediction accuracy than the features of oculomotor efficiency in distinguishing OCD from HCs. Our results suggested that OCD has concurrent deficits in oculomotor hyperactivity and oculomotor efficiency, which may originate from a common inhibitory dysfunction.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"180 ","pages":"Pages 402-410"},"PeriodicalIF":3.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Menahem Krakowski , Matthew J. Hoptman , Pal Czobor
{"title":"Dysfunctional activation of the default mode network in response inhibition in schizophrenia","authors":"Menahem Krakowski , Matthew J. Hoptman , Pal Czobor","doi":"10.1016/j.jpsychires.2024.11.020","DOIUrl":"10.1016/j.jpsychires.2024.11.020","url":null,"abstract":"<div><div>The aim of this study was to characterize dysfunctional cerebral activation in patients with schizophrenia while they performed a response inhibition task. To achieve this, performance on the task and functional magnetic resonance imaging (fMRI) were compared between healthy control subjects (HC) and patients with schizophrenia (SZ). We focused on the default mode network (DMN), as there is strong evidence in the literature that lack of DMN suppression in schizophrenia is associated with cognitive impairment including poor response inhibition. fMRI was used to measure blood-oxygen-level-dependent activation in 84 subjects (44 SZ and 40 HC) while they performed a Go NoGo task. The subjects were also evaluated for psychiatric symptoms and immediate visual memory.</div><div>SZ performed more poorly than HC on the task; they had a higher number of commission errors. On the fMRI, the patients consistently evidenced higher activation than the controls in several areas of the default mode network (DMN) including the precuneus, rostral anterior cingulate, parahippocampus and insula. The higher brain activation in the patients with schizophrenia indicates a failure to deactivate the DMN while they perform the response inhibition task. These findings point to the importance of DMN dysfunction as an underlying cause of impairment in response inhibition in schizophrenia. DMN disruptions play an essential role in the cognitive impairment present in schizophrenia.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"180 ","pages":"Pages 411-417"},"PeriodicalIF":3.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating catatonia care in the psychiatric emergency room: A retrospective study","authors":"Samuel Reinfeld","doi":"10.1016/j.jpsychires.2024.11.015","DOIUrl":"10.1016/j.jpsychires.2024.11.015","url":null,"abstract":"<div><h3>Background</h3><div>Catatonia, characterized by motor, affective, and speech disturbances, is a prevalent yet frequently misdiagnosed syndrome in the psychiatric domain, with reported prevalence ranging from 5% to 18%. This study aimed to ascertain the incidence of catatonia diagnoses and the quality of care provided within the psychiatric emergency room (ER), while also evaluating psychiatrists' general awareness of the syndrome through a survey.</div></div><div><h3>Methods</h3><div>A retrospective analysis of psychiatric ER records spanning June 18th to August 20th, 2022, was conducted to assess catatonia diagnosis frequency and treatment approaches. A Google Survey was distributed to full-time psychiatrists in the ER, querying their knowledge about catatonia prevalence, diagnostic modalities, and treatment strategies.</div></div><div><h3>Results</h3><div>Analysis of 1118 patient records revealed a catatonia diagnosis rate of 0.36% (four cases) in the psychiatric ER. Remarkably, 75% of diagnosed patients were assessed by a single psychiatrist among nine available. Survey responses from all nine ER psychiatrists highlighted that 44% considered encountering catatonia as infrequent, while 33% regarded it as generally rare. Furthermore, 33% expressed willingness to employ potent antipsychotic interventions.</div></div><div><h3>Conclusion</h3><div>The study revealed a markedly low catatonia detection rate in the psychiatric ER, coupled with inconsistent treatment approaches. Survey findings reflected a considerable proportion of psychiatrists holding outdated perceptions of catatonia.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"180 ","pages":"Pages 439-442"},"PeriodicalIF":3.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Yoga for children and adolescents: A decade-long integrative review on feasibility and efficacy in school-based and psychiatric care interventions","authors":"Nóra Kerekes , Alexandra Söderström , Christine Holmberg , Britt Hedman Ahlström","doi":"10.1016/j.jpsychires.2024.11.016","DOIUrl":"10.1016/j.jpsychires.2024.11.016","url":null,"abstract":"<div><h3>Background</h3><div>There has been a concerning rise in mental illness among children and adolescents. Attention deficit and hyperactivity disorder, autism spectrum disorder, anxiety, and depression are the most prevalent diagnoses in this field. Research suggests that yoga as a complementary treatment offers relief from mental symptoms and has already been successfully applied in adult healthcare settings.</div></div><div><h3>Objective</h3><div>The objective of this review is to provide an integrative summary of the existing research on the feasibility and effectiveness of yoga as a school-based intervention and complementary intervention in psychiatric care for children and adolescents.</div></div><div><h3>Methods</h3><div>An integrative literature review was conducted, employing a combined quantitative and qualitative approach. The review was based on 16 selected articles, which presented data from more than 1000 children and adolescents aged 5–19 years and encompassed a variety of study designs. Literature searches were carried out systematically and unsystematically in February 2023, across three chosen databases.</div></div><div><h3>Results</h3><div>Yoga interventions consistently yielded positive outcomes in multiple domains. In this review, the findings are categorized into five themes: alleviated symptoms of psychiatric conditions; strengthened self-control and behavioral changes; improved cognitive functioning; refined relaxation; enhanced well-being. By improving psychiatric symptoms, enhancing self-control, promoting relaxation, and fostering overall well-being, yoga offers a multifaceted approach toward improving mental and physical health in children and adolescents.</div></div><div><h3>Conclusion</h3><div>This comprehensive review presents compelling evidence of the positive benefits of yoga as a complementary intervention for a wide range of psychological symptoms and cognitive functions in children and adolescents. In order to further validate and consolidate these findings, there is a pressing need for future studies to provide more robust evidence and a deeper understanding of the effectiveness of yoga as a complementary intervention in this context.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"180 ","pages":"Pages 489-499"},"PeriodicalIF":3.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}