Tiffany Junchen Tao , Li Liang , Huinan Liu , Tsz Wai Li , George A. Bonanno , Wai Kai Hou
{"title":"Trajectories of daily routine disruptions as functions of depressive and anxiety symptom trajectories and social determinants: A multi-wave population survey in Hong Kong","authors":"Tiffany Junchen Tao , Li Liang , Huinan Liu , Tsz Wai Li , George A. Bonanno , Wai Kai Hou","doi":"10.1016/j.jpsychires.2025.07.004","DOIUrl":"10.1016/j.jpsychires.2025.07.004","url":null,"abstract":"<div><h3>Context</h3><div>As one of the largest-scale public health disasters, the COVID-19 pandemic has significantly disrupted daily routines and resulted in poorer mental health especially among more socioeconomically disadvantaged populations.</div></div><div><h3>Objective</h3><div>In this study, we investigated trajectories of routine disruptions and their relationships with mental health symptom trajectories, as well as socioeconomic characteristics between 2020 and 2022 amid the COVID-19 pandemic.</div></div><div><h3>Methods</h3><div>A population-representative sample in Hong Kong (<em>N</em> = 1333) was recruited to complete self-report instruments at the pandemic's acute phase (February–July 2020, T1), and again at 1-year (March–August 2021, T2) and 1.5-year (September 2021–February 2022, T3) follow-ups. Respondents reported primary and secondary routine disruptions, and depressive and anxiety symptoms.</div></div><div><h3>Results</h3><div>Growth mixture modeling (GMM) identified four trajectories of routine disruptions: <em>sustained regularity</em> (55.66 %–74.57 %), <em>recovery from disruptions</em> (5.10 %–14.40 %), <em>delayed disruptions</em> (10.20 %–14.03 %), and <em>chronic disruptions</em> (6.30 %–19.73 %). Four symptom trajectories were also demonstrated: resilience, recovery, delayed distress, and chronic distress. Respondents showing <em>sustained regularity</em> and <em>recovery from disruptions</em> were more likely to be dependent (vs. employed) and demonstrate a resilience or recovery trajectory on mental health symptoms. Respondents showing <em>chronic</em> and <em>delayed disruptions</em> were more likely to be younger with lower socioeconomic status and demonstrate a chronic or delayed distress trajectory on mental health symptoms.</div></div><div><h3>Conclusion</h3><div>People's routine disruptions displayed heterogeneous trajectories over time. Sustained regularity was the most prevalent among others. Access to socioeconomic resources could dictate optimal behavioral adjustment. Patterns of daily routine disruptions demonstrate a concordance with patterns of psychological adjustment. These results provide an initial evidence base for advancing the nature and role of behavioral adjustment during and after large-scale disasters.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"190 ","pages":"Pages 302-311"},"PeriodicalIF":3.2,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144841351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriel Salmón-Gómez, Paula Suárez-Pinilla, Esther Setién-Suero, Carlos Martínez-Asensi, Rosa Ayesa-Arriola
{"title":"FoxP2 and Schizophrenia: a systematic review.","authors":"Gabriel Salmón-Gómez, Paula Suárez-Pinilla, Esther Setién-Suero, Carlos Martínez-Asensi, Rosa Ayesa-Arriola","doi":"10.1016/j.jpsychires.2025.07.016","DOIUrl":"https://doi.org/10.1016/j.jpsychires.2025.07.016","url":null,"abstract":"<p><p>Schizophrenia (SCZ) is a neurodevelopmental psychiatric disorder characterized by impaired information processing and neural circuit dysfunction. FoxP2, an ontological transcription factor, is crucial for brain development and neuronal differentiation. This systematic review explores the association between FoxP2 polymorphisms and SCZ using PRISMA guidelines to search PubMed and EMBASE. Articles were selected based on predefined criteria, and their findings were systematically evaluated. While no FoxP2 polymorphism was significantly associated with SCZ risk, specific variants showed relevance to clinical manifestations. Rs10447760 is linked to symptom severity and Body Mass Index (BMI), rs1456031 correlated with childhood parental abuse and auditory verbal hallucinations (AVH), rs2253478 is associated with poverty of speech, and rs2396753 is significantly related to reduced grey matter density (GMD) in SCZ patients. These findings suggest that FoxP2 polymorphisms may influence SCZ-related traits such as weight gain, language impairments, reduced GMD, and trauma-associated AVH. However, the limited sample sizes and scope of current studies highlight the need for further research to clarify FoxP2's role in less explored aspects of SCZ.</p>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"190 ","pages":"205-215"},"PeriodicalIF":3.2,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The association between problematic social media use and attention deficit/hyperactivity disorder symptomatology: a systematic review and meta-analysis","authors":"Jiahui Ding , Zihan Liu , Miao Chao","doi":"10.1016/j.jpsychires.2025.07.009","DOIUrl":"10.1016/j.jpsychires.2025.07.009","url":null,"abstract":"<div><h3>Background</h3><div>Problematic social media use (PSMU) is becoming increasingly common, with various studies highlighting a notable correlation with Attention Deficit/Hyperactivity Disorder (ADHD) symptomatology.</div></div><div><h3>Methods</h3><div>A comprehensive search strategy was employed to identify relevant studies from the following databases: PubMed, Web of Science, EBSCO, and ProQuest. Meta-analysis was performed using Comprehensive Meta Analysis software with a random effects model.</div></div><div><h3>Results</h3><div>The meta-analysis included 15 studies with a total of 35,223 participants. The analysis revealed a moderate positive correlation between ADHD symptomatology and PSMU (<em>r</em> = 0.361, 95 % <em>CI</em> [0.297, 0.421]). Subgroup analyses identified several significant moderators: data collection timing (<em>r</em><sub>After-COVID-19</sub>><em>r</em><sub><em>B</em>efore-COVID-19</sub>), assessment tools for PSMU (<em>r</em><sub>BSMAS</sub> > <em>r</em><sub>SMDS</sub> > <em>r</em><sub>Others</sub>), and assessment tools for ADHD (<em>r</em><sub>ASRS</sub> > <em>r</em><sub>Others</sub>). Additionally, the mean age of participants emerged as a significant moderator in the meta-regression analysis.</div></div><div><h3>Conclusions</h3><div>The evidence supports a significant association between ADHD symptomatology and PSMU. These findings have implications for future research and clinical practice.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"189 ","pages":"Pages 544-553"},"PeriodicalIF":3.2,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144772252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthew F. Thompson , Laura A. Novak , Heidi H. Meyer , Melanie L. Schwandt , Amanda K. Gilmore , David Goldman , Vijay A. Ramchandani , Nancy Diazgranados , Jeremy W. Luk
{"title":"Dimensions of trait and task-based impulsivity associated with alcohol use disorder and history of suicidality","authors":"Matthew F. Thompson , Laura A. Novak , Heidi H. Meyer , Melanie L. Schwandt , Amanda K. Gilmore , David Goldman , Vijay A. Ramchandani , Nancy Diazgranados , Jeremy W. Luk","doi":"10.1016/j.jpsychires.2025.07.019","DOIUrl":"10.1016/j.jpsychires.2025.07.019","url":null,"abstract":"<div><h3>Background</h3><div>Impulsivity underlies both alcohol misuse and suicidal behavior, but limited research has examined whether impulsivity dimensions vary by problematic drinking and history of suicidality. The objective of this study was to examine differences in trait and task-based impulsivity dimensions based on clinical assessment of alcohol use disorder (AUD), suicidal ideation (SI), and suicidal attempt (SA).</div></div><div><h3>Methods</h3><div>1250 participants from the National Institute on Alcohol Abuse and Alcoholism Natural History Protocol were categorized into 5 groups: neither suicidality nor AUD (“neither”; 49.1 %), suicidality without AUD (“SI-SA Only”; 3.0 %), AUD without suicidality (“AUD Only”; 30.5 %), AUD with SI (“AUD-SI”; 12.1 %), and AUD with SA (“AUD-SA”; 5.2 %). We measured impulsivity using the UPPS-P Impulsive Behavior Scale, the Barratt Impulsiveness Scale (BIS), and the delay discounting task. Linear regression models were conducted.</div></div><div><h3>Results</h3><div>Compared with the Neither group, negative urgency, lack of premeditation, lack of perseverance, positive urgency, and all BIS subscales (attentional, motor, and non-planning) were consistently higher among individuals with AUD only (Hedges's <em>g</em> ranged 0.56–1.13), and the scores were even higher among those who also endorsed history of SI (Hedges's <em>g</em> ranged 0.90–1.83) or SA (Hedges's <em>g</em> ranged 1.14–2.16). These findings were robust against adjustment for covariates. Mean score on the delay discounting task was highest in the AUD-SA group, but group differences were not statistically significant after adjusting for covariates.</div></div><div><h3>Conclusion</h3><div>Individuals with both current AUD and suicide attempt history scored the highest across multiple dimensions of trait impulsivity. Findings underscore the importance of suicide assessment and prevention in the context of AUD treatment.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"190 ","pages":"Pages 258-266"},"PeriodicalIF":3.2,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144831208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Brain microstructure alterations in bipolar disorder subtypes revealed by diffusion kurtosis imaging","authors":"Moto Nakaya , Kouhei Kamiya , Ryo Kurokawa , Akira Kunimatsu , Yuichi Suzuki , Shinsuke Koike , Naohiro Okada , Kiyoto Kasai , Osamu Abe","doi":"10.1016/j.jpsychires.2025.07.006","DOIUrl":"10.1016/j.jpsychires.2025.07.006","url":null,"abstract":"<div><div>Bipolar disorder (BD) is often associated with extensive changes in white matter (WM) microstructure. While diffusion tensor imaging (DTI) has been used in BD studies, diffusion kurtosis imaging (DKI) has rarely been explored, particularly concerning the different subtypes of BD. This cross-sectional study compared DTI and DKI metrics of the brain WM in participants with BD type I (BD-I) and II (BD-II) and in healthy controls (HC). The correlation between the diffusion metrics and the clinical scores was examined. In total, 40 patients with BD and 42 HC were enrolled. Diffusion metrics across groups were examined using tract-based spatial statistics. Patients with BD-I showed lower fractional anisotropy and kurtosis values throughout the WM compared with the values found in patients with BD-II and HC. Comparison between the BD subtypes suggested that patients with BD-I had more prominent WM disruption. Diffusion kurtosis imaging analyses demonstrated a greater spatial extent of significant effects across different BD subtypes than could be achieved by DTI. Our results indicated that DKI can enhance the sensitivity to WM microstructural alterations in BD and that this technique can provide valuable insights into the biological differences between BD-I and BD-II.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"189 ","pages":"Pages 505-512"},"PeriodicalIF":3.2,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144758134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The efficacy and safety of theta burst stimulation for bipolar depression: a systematic review and meta-analysis","authors":"Itsuki Terao , Wakako Kodama","doi":"10.1016/j.jpsychires.2025.07.021","DOIUrl":"10.1016/j.jpsychires.2025.07.021","url":null,"abstract":"<div><h3>Introduction</h3><div>Randomized controlled trials demonstrating the efficacy of theta burst stimulation (TBS) for bipolar depression have been accumulating. However, the previous meta-analysis failed to detect a significant difference in efficacy compared to sham stimulation.</div></div><div><h3>Methods</h3><div>A comprehensive search for randomized controlled trials was carried out using multiple databases, including PubMed, the Cochrane Library, CINAHL, and <span><span>ClinicalTrials.gov</span><svg><path></path></svg></span>. A random-effects meta-analysis was employed to assess and compare the antidepressant efficacy, tolerability, and acceptability of TBS versus sham stimulation.</div></div><div><h3>Results</h3><div>A total of 7 randomized sham-controlled trials, encompassing 168 participants, met the inclusion criteria. TBS demonstrated superior antidepressant efficacy over sham stimulation, with a standardized mean difference of 0.67 (95 % confidence interval [CI]: 0.03 to 1.31). The odds ratio (OR) for clinical response favored TBS (OR = 2.93, 95 % CI: 1.32–6.52), while the OR in remission was not statistically significant (OR = 2.12, 95 % CI: 0.85–5.27). Acceptability, assessed by all-cause discontinuation, was comparable between groups (OR = 0.48, 95 % CI: 0.12–1.96).</div></div><div><h3>Conclusions</h3><div>Theta burst stimulation appears to be a promising, effective, and safe treatment for bipolar depression. Further large-scale and long-term randomized controlled trials are warranted.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"190 ","pages":"Pages 47-51"},"PeriodicalIF":3.2,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144763740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ariel B Ganz, Benjamin Rolnik, Meenakshi Chakraborty, Jacob Wilson, Cyrus Tau, Matthew Sharp, Dallen Reber, George M Slavich, Michael P Snyder
{"title":"Corrigendum to \"Effects of an immersive psychosocial training program on depression and well-being: A randomized clinical trial\" [J. Psychiatr. Res. (2022) 150: 292-299].","authors":"Ariel B Ganz, Benjamin Rolnik, Meenakshi Chakraborty, Jacob Wilson, Cyrus Tau, Matthew Sharp, Dallen Reber, George M Slavich, Michael P Snyder","doi":"10.1016/j.jpsychires.2025.06.035","DOIUrl":"https://doi.org/10.1016/j.jpsychires.2025.06.035","url":null,"abstract":"","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zunwei Zhang , Yang Xue , Miaoshui Bai , Hanyu Dong , Zakaria Ahmed Mohamed , Tiantian Wang , Feiyong Jia
{"title":"Reading abilities and cognitive processing in grade 3 children with ADHD comorbid with developmental dyslexia","authors":"Zunwei Zhang , Yang Xue , Miaoshui Bai , Hanyu Dong , Zakaria Ahmed Mohamed , Tiantian Wang , Feiyong Jia","doi":"10.1016/j.jpsychires.2025.07.005","DOIUrl":"10.1016/j.jpsychires.2025.07.005","url":null,"abstract":"<div><div>Attention Deficit/Hyperactivity Disorder (ADHD) frequently co-occurs with developmental dyslexia (DD) (ADHD + DD). Children with ADHD + DD manifest low achievement in reading performance and cognitive abilities. There is, however, a lack of research exploring the association between reading abilities and cognitive processing based on the Planning–Attention–Simultaneous–Successive (PASS) theory, particularly in those with ADHD + DD and ADHD subtypes (e.g., the predominantly inattentive subtype (ADHD-I), predominantly hyperactive/impulsive subtype (ADHD-H), and combined subtype (ADHD-C)). In this study, we enrolled a total of 318 grade 3 children (including 99 ADHD + DD, 103 ADHD-I, 7 ADHD-H, 22 ADHD-C and 87 typically developing (TD) children), all of whom were assessed on measures of reading ability and Das-Naglieri Cognitive Assessment System (DN: CAS). Our key findings reveal that ADHD + DD have an imbalance in their intelligence structure, showing a certain advantage in Performance IQ, while their Verbal IQ tends to be relatively weaker. In terms of DN: CAS cognitive processing, children with ADHD-H exhibit impairments exclusively in Planning, while other cognitive domains remain intact. ADHD + DD children not only exhibit the typical characteristics of ADHD, but also show these traits in a more severe, including deficits in Successive processing. Regression analysis revealed that Successive processing might negatively affect character recognition in children with ADHD + DD. The study highlights that in the context of severely low Attention and Planning processing, Successive processing plays a very different and even negative role in reading ability. This needs to be taken into account when designing remedial interventions for children with ADHD + DD.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"189 ","pages":"Pages 521-527"},"PeriodicalIF":3.2,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144758136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Craig J. Bryan, Samantha E. Daruwala, Melanie L. Bozzay
{"title":"Temporal dynamics of the wish to live and wish to die signal near-term increases in suicidal thinking in a veteran sample","authors":"Craig J. Bryan, Samantha E. Daruwala, Melanie L. Bozzay","doi":"10.1016/j.jpsychires.2025.06.039","DOIUrl":"10.1016/j.jpsychires.2025.06.039","url":null,"abstract":"<div><div>Preventing suicide is challenging because there are no ways to reliably determine when someone is about transition from a lower to higher risk state. Dynamic interactions between the wish to live (WTL) and die (WTD) may differentiate higher from lower risk suicide states and signal near-term transitions of increasing risk. In this cohort design, clinical trial participants with posttraumatic stress disorder (PTSD) received prompts to complete a brief survey on their phone 4 times per day for 14 consecutive days at pseudorandom times. Participants were asked to rate their WTL, WTD, suicidal desire, and desire for self-preservation using 4 items from the Scale for Suicide Ideation (SSI). Participants were 116 military personnel and veterans diagnosed with PTSD (69.8 % male, 76.7 % White, M age = 47.2 ± 12.1 years). Multilevel dynamical systems modeling revealed that the WTL and WTD changed in coordinated and opposing directions except when suicidal desire was most severe and was about to worsen at the next time point. Under these conditions, WTL and WTD switched to an oscillatory pattern. Temporal patterns in WTL and WTD differ when people report lower versus higher risk suicidal states. Oscillations in WTL and WTD signal near-term worsening of suicidal desire. Multiple qualitatively distinct suicide risk states exist, suggesting suicide risk is categorical, not continuous.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"189 ","pages":"Pages 471-478"},"PeriodicalIF":3.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144604379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shu Wang , Linli Zou , Xiaolu Lai , Jingfen Chen , Daniel Krewski , Shi Wu Wen , Ri-hua Xie
{"title":"Association between blood pressure trajectories during pregnancy and childbirth-related post-traumatic stress disorder symptoms","authors":"Shu Wang , Linli Zou , Xiaolu Lai , Jingfen Chen , Daniel Krewski , Shi Wu Wen , Ri-hua Xie","doi":"10.1016/j.jpsychires.2025.06.037","DOIUrl":"10.1016/j.jpsychires.2025.06.037","url":null,"abstract":"<div><h3>Background</h3><div>Research on the association between blood pressure changes during pregnancy and childbirth-related post-traumatic stress disorder (CB-PTSD) is scarce. This study aimed to explore the impact of blood pressure trajectories during pregnancy on CB-PTSD symptoms.</div></div><div><h3>Methods</h3><div>This cohort study was conducted from October 2022 to August 2023 in Foshan,China. Eligible women were recruited 2–3 days postpartum, with pregnancy blood pressure data retrospectively retrieved from medical records. The Perinatal Post-Traumatic Stress Disorder Questionnaire (PPQ) was used to assess CB-PTSD symptoms 42 days postpartum. A latent class growth model was employed to identify blood pressure trajectories, and logistic regression models were used to estimate the associations between blood pressure trajectories and CB-PTSD symptoms.</div></div><div><h3>Results</h3><div>Among the 709 women included in the study, 67 (9.4 %) exhibited clinically significant CB-PTSD symptoms within 42 days postpartum. Three distinct systolic blood pressure (SBP) and diastolic blood pressure (DBP) trajectories and two pulse pressure (PP) trajectories were identified. Logistic regression analysis showed that the risk of CB-PTSD symptoms was lower in the high-declining PP group (OR = 0.59, 95 %CI = 0.36–0.97) than the low-increasing PP group. After adjusting for confounders, the medium-slow-increasing SBP group (OR = 0.52, 95 %CI = 0.28–0.94) had a lower risk of CB-PTSD symptoms than the low-fast-increasing SBP group. The high-declining PP group (OR = 0.44, 95 %CI = 0.25–0.79) remained associated with a lower risk of CB-PTSD symptoms than the low-increasing PP group after adjustment.</div></div><div><h3>Conclusions</h3><div>Different patterns of blood pressure changes during pregnancy are associated with CB-PTSD symptoms, with wider blood pressure fluctuations potentially exerting a greater impact. Future research should explore the underlying biological and psychological mechanisms of these associations.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"189 ","pages":"Pages 455-463"},"PeriodicalIF":3.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144534633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}