H Delamain, R Saunders, M Tanzer, P Luyten, P Fonagy, C Campbell
{"title":"Identifying subgroups of individuals based on their epistemic stance, attachment dimensions and childhood trauma: A latent profile analysis.","authors":"H Delamain, R Saunders, M Tanzer, P Luyten, P Fonagy, C Campbell","doi":"10.1016/j.jpsychires.2024.12.033","DOIUrl":"10.1016/j.jpsychires.2024.12.033","url":null,"abstract":"<p><strong>Background: </strong>The present study examines the interplay between epistemic stance, attachment dimensions, and childhood trauma in relation to specific demographic factors and mental health outcomes. This study aims to understand how these factors form distinct profiles among individuals, to identify those at risk of mental health concerns.</p><p><strong>Method: </strong>Latent Profile Analysis (LPA) was employed on a dataset from the general population (n = 500) to identify subgroups of individuals based on their epistemic stance (mistrust and credulity), attachment dimensions, and childhood trauma. Group comparison tests examined differences in sociodemographic variables across the profiles, whilst linear regression analyses investigated between-profile variations in mental health and wellbeing measures.</p><p><strong>Results: </strong>The LPA revealed a four-profile solution as the most suitable fit for the data. The latent profiles were characterised as follows: LP1 (14% of the sample; high levels of mistrust and low scores on all other measures), LP2 (62% of the sample; average scores on all measures), LP3 (15% of the sample; highest scores on all measures), and LP4 (9% of the sample; lowest scores on all measures). Between-profile significant differences were found for relationship status and education levels. Linear regression analyses demonstrated variations across the profiles for mental health symptoms and wellbeing measures.</p><p><strong>Conclusions: </strong>This study identified four distinct profiles with specific combinations of epistemic stance, attachment dimensions, and childhood trauma. These profiles were associated with differing levels of mental health symptom severity and wellbeing, suggesting their potential utility in informing preventive strategies targeting individuals at highest risk of negative outcomes.</p>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"181 ","pages":"701-708"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intergenerational effects of the Holocaust following the October 7 attack in Israel.","authors":"Amit Shrira, Lee Greenblatt-Kimron, Yuval Palgi","doi":"10.1016/j.jpsychires.2024.11.067","DOIUrl":"10.1016/j.jpsychires.2024.11.067","url":null,"abstract":"<p><p>Descendants of traumatized individuals may exhibit latent vulnerability, meaning they are typically well-functioning yet more vulnerable to stressful and traumatic events. Nevertheless, such vulnerability is not omnipresent, and some descendants are more prone than others to develop posttraumatic disorder (PTSD) and other psychopathologies. Ancestral PTSD was suggested as an aggravating factor for intergenerational effects. The current study examined whether Holocaust descendants (i.e., children and grandchildren of Holocaust survivors) show unique posttraumatic reactions to the October 7 terrorist attack and the ensuing war and whether parental/grandparental PTSD exacerbated these reactions. A web-based random sample of 582 Israeli Jews completed questionnaires a year before the October 7 terrorist attack (Wave 1, 2022) and two months after the attack and into the war (Wave 3, December 2023). Results showed that pre-war probable PTSD rates were similar across the study groups (10.4% and 11.5% among Holocaust descendants and descendants of those not directly exposed to the Holocaust, respectively). In contrast, probable PTSD rates during the war mainly increased among Holocaust descendants (20.9% and 11.5% among Holocaust and comparison descendants, respectively). Higher probable PTSD rates were especially noticeable in Wave 3 among Holocaust descendants who reported that their parents/grandparents had probable PTSD even after controlling Wave 1 probable PTSD, background characteristics, and levels of traumatic exposure. The findings have important implications for understanding the intergenerational effects of trauma as they strongly support the latent vulnerability hypothesis three generations after ancestral trauma, and further suggest that ancestral PTSD plays a major role in aggravating such vulnerability.</p>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"181 ","pages":"298-303"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of five traditional Chinese medicine exercises on insomnia: A systematic review and network meta-analysis.","authors":"Liang Li, Jiuzhu Liang, Tonggang Fan","doi":"10.1016/j.jpsychires.2024.12.004","DOIUrl":"10.1016/j.jpsychires.2024.12.004","url":null,"abstract":"<p><strong>Background: </strong>Insomnia has become a significant public health issue. Traditional Chinese medicine (TCM) exercises are used in the treatment of insomnia. The purpose of this study was to compare the effectiveness of five TCM exercise regimens (yijinjing, wuqinxi, liuzijue, baduanjin, and taijiquan) as an intervention for insomnia.</p><p><strong>Method: </strong>We searched six databases-China National Knowledge Infrastructure, Wanfang, PubMed, Embase, Cochrane Library, and Web of Science-for relevant articles, published in English or Chinese, from their inception till April 2024. Data from the included literature were analyzed and evaluated using a network meta-analysis of random effects with a frequency-based framework.</p><p><strong>Results: </strong>A total of 50 papers were included, comprising 4226 patients with insomnia. The results of the direct comparison of the five TCM exercises (yijinjing, wuqinxi, liuzijue, baduanjin, and taijiquan) with the control group indicated that all five TCM exercises were able to improve insomnia (p < 0.05). In the indirect comparison between the five TCM exercises, there was a significant difference between liuzijue and wuqinxi (p < 0.05), and taijiquan (p < 0.05). We used the areas under the receiver operating curves to rank the effectiveness of the five TCM exercises in treating insomnia as follows: liuzijue (Surface Under the Cumulative Ranking Curve, SUCRA = 96.4%) > yijinjing (SUCRA = 72.6%) > baduanjin (SUCRA = 55.1%) > taijiquan (45%) > wuqinxi (SUCRA = 30.9%).</p><p><strong>Conclusion: </strong>The studied TCM exercises can be used as an effective treatment for insomnia, and liuzijue is the most effective of the studied options.</p>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"181 ","pages":"312-319"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Philippe Kerr, Robert-Paul Juster, Sonia J Lupien, Marie-Claude Delisle
{"title":"Effects of antidepressant type on allostatic load of male and female psychiatric outpatients.","authors":"Philippe Kerr, Robert-Paul Juster, Sonia J Lupien, Marie-Claude Delisle","doi":"10.1016/j.jpsychires.2024.11.056","DOIUrl":"10.1016/j.jpsychires.2024.11.056","url":null,"abstract":"<p><p>Sex differences and antidepressant use are not systematically accounted for in studies measuring physiological dysregulations associated with chronic stress and allostatic load (AL) in neuropsychiatry. Critically, assessing commonly prescribed antidepressant medications, such as selective serotonin reuptake inhibitors (SSRIs) and selective serotonin and norepinephrine reuptake inhibitors (SNRIs) could help monitor potential iatrogenic effects on AL and health that are associated with prolonged antidepressant use. The objective of this exploratory analysis was to investigate how male and female psychiatric outpatients using either SSRIs or SNRIs differ in their AL indices. To achieve this, we used data from a larger project collecting administrative, medical, and biological data among psychiatric outpatients of the Anjou Clinic for Mood and Anxiety Disorders, based in Montreal, Canada (n = 116). Sociodemographic variables included age and birth-assigned sex. We calculated AL using 10 biomarkers reflecting cardiovascular (systolic blood pressure, diastolic blood pressure, pulse) and metabolic (glucose, creatinine, total cholesterol, high density lipoprotein cholesterol (HDL), total cholesterol/HDL ratio, triglycerides, body mass index) functioning. Psychiatric medications were classified using the Anatomical and Therapeutic Classification system. We found that relative to female outpatients, male outpatients showed significantly higher AL levels. In addition, relative to SSRI users, SNRI users had significantly higher AL levels. However, there were no interactions effects between birth-assigned sex and antidepressant types on AL. We discuss the potential clinical implications of our findings, as well as directions for future studies that aim to investigate AL among male and female patients using antidepressants.</p>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"181 ","pages":"373-378"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anastasia Korezelidou, Annika Welte, Anna Oster, Lieselotte Mahler
{"title":"Overcoming the lack of alternatives - Changes in the use of coercive measures after implementation of the recovery-oriented \"Weddinger Modell\" in acute psychiatric care.","authors":"Anastasia Korezelidou, Annika Welte, Anna Oster, Lieselotte Mahler","doi":"10.1016/j.jpsychires.2024.11.032","DOIUrl":"10.1016/j.jpsychires.2024.11.032","url":null,"abstract":"<p><strong>Introduction: </strong>Due to the ethical conflict potential and far-reaching negative consequences of coercive measures (CM) in acute psychiatry, approaches to reduce the use of CM are investigated increasingly. One approach is the recovery-, resilience-, and patient-centered \"Weddinger Modell\" (WM) for inpatient psychiatric care. The present study evaluates the WM and investigates whether cases affected by CM, cases affected by seclusion or restraint, and the number, total duration, and average individual duration of CM per case are significantly reduced after WM-implementation.</p><p><strong>Methodology: </strong>This is a retrospective study based on data from patient records. The main implementation phase of the WM (WM-MIP) was defined as the period between May and August 2020. Cases treated between July 2019 and June 2021 were included. To compare changes in the use of CM before and after the WM-MIP, different multilevel regression models were applied (with n = 1656 cases and n = 194 cases affected by CM, respectively).</p><p><strong>Results: </strong>Cases affected by seclusion and the number of CM per case were significantly reduced after WM-MIP. No significant difference was found in terms of CM affected (total) or restraint affected, total CM duration, and average single CM duration per case.</p><p><strong>Discussion: </strong>The results indicate a positive effect of the WM with regard to the reduction of CM. In terms of further spread of the WM, the implementation process should be studied in detail, especially to identify key components to reduce CM.</p><p><strong>Conclusion: </strong>The WM should be considered as an approach to reduce CM.</p>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"181 ","pages":"405-410"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cheng Xie, Chen Xue, Yuxi Li, Xiaobo Liu, Donglin Zhong, Qizu Jin, Juan Li, Rongjiang Jin
{"title":"The characteristics of event-related potentials in generalized anxiety disorder: A systematic review and meta-analysis.","authors":"Cheng Xie, Chen Xue, Yuxi Li, Xiaobo Liu, Donglin Zhong, Qizu Jin, Juan Li, Rongjiang Jin","doi":"10.1016/j.jpsychires.2024.12.016","DOIUrl":"10.1016/j.jpsychires.2024.12.016","url":null,"abstract":"<p><strong>Objectives: </strong>Previous studies have reported inconsistent findings regarding event-related potentials (ERPs) abnormalities in individuals with generalized anxiety disorder (GAD). This meta-analysis aimed to systematically review and synthesize the existing evidence on ERP alterations in individuals with GAD.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted in PubMed, the Cochrane Library, Excerpta Medica Database, Web of Science, China National Knowledge Infrastructure (CNKI), Chinese Science and Technology Periodical Database (VIP), Wanfang database, and China Biology Medicine (CBM) databases from inception to November 11, 2024. Gray literature and reference lists were also manually searched. Studies investigating ERP component differences between individuals with GAD and healthy controls were included. Two independent reviewers conducted study selection, data extraction, and risk of bias assessment. Influence and sensitivity analyses were performed to assess the robustness of the pooled results. Effect sizes (SMD, Hedge's g) were calculated for latency and amplitude differences. Heterogeneity was assessed using the I<sup>2</sup> statistic. Meta-regression and subgroup analyses were conducted to explore the source of heterogeneity. Trim-and-fill analyses were applied to assess potential publication bias. Data synthesis was performed using R (version 4.2.3) software.</p><p><strong>Results: </strong>A total of 37 studies involving 1086 individuals with GAD and 1315 healthy controls were included. The overall risk of bias was rated as low for 25 studies and moderate for 12 studies. Ten ERP components were included in the quantitative meta-analysis: P3, N2, N1, P2, Error Related Negativity (ERN), Correction Related Negativity (CRN), Mismatch Negativity (MMN), P1 (amplitude), Pe, and LPP. Pooled results indicated that individuals with GAD exhibited decreased P3 amplitude (g = -0.54, 95% CI: -0.70 to -0.38, I<sup>2</sup> = 20%, P = 0.22) and increased ERN amplitude (g = -0.42, 95% CI: -0.72 to -0.12, I<sup>2</sup> = 40%, P = 0.11) compared to healthy controls. In addition, delayed latency of P3 (g = 0.43, 95% CI: 0.09 to 0.78, I<sup>2</sup> = 75%, P < 0.01), N2 (g = 0.36, 95% CI: 0.11 to 0.62, I<sup>2</sup> = 30%, P = 0.20), and MMN (g = 0.63, 95% CI: 0.52 to 0.75, I<sup>2</sup> = 0%, P < 0.0001) was observed in individuals with GAD. Due to the limited number of included studies, the results of N170, N1/P2, N270, N400, VPP, BAEP, P1 (latency), P50, EPN and Nf were summarized narratively. Individuals with GAD were reported to have increased N170, N400, and VPP amplitude and delayed P1 latency compared to healthy controls. Age, sex ratio, sample size, diagnostic criteria, task-related modality, and paradigm were identified as potential influencing factors of ERP characteristics.</p><p><strong>Conclusions: </strong>Individuals with GAD exhibit increased ERN amplitude and decreased P3 amplitude in contrast ","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"181 ","pages":"470-483"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Can Xu, Hiba Mutwalli, Rowan Haslam, Johanna Louise Keeler, Janet Treasure, Hubertus Himmerich
{"title":"C-reactive protein (CRP) levels in people with eating disorders: A systematic review and meta-analysis.","authors":"Can Xu, Hiba Mutwalli, Rowan Haslam, Johanna Louise Keeler, Janet Treasure, Hubertus Himmerich","doi":"10.1016/j.jpsychires.2024.12.039","DOIUrl":"10.1016/j.jpsychires.2024.12.039","url":null,"abstract":"<p><p>Studies suggest that there is a relationship between inflammatory diseases, inflammatory markers such as C-reactive protein (CRP) and psychiatric disorders. In eating disorders, cross-sectional studies have recently examined peripheral CRP levels in blood serum and plasma, which allow a comprehensive meta-analysis. This systematic review and meta-analysis examined studies from three databases, measuring CRP levels in people with eating disorders, following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. A total n = 14 publications were included into the systematic review. Of these, n = 13 cross-sectional papers with N = 700 participants were meta-analysed, n = 11 in anorexia nervosa (AN) and n = 2 in binge eating disorder (BED). One study of the total n = 14 was narratively summarised because it was not suitable for inclusion into the meta-analysis. In the cross-sectional analyses, CRP levels were significantly lower in people with AN compared to health controls (HCs), but CRP level were higher in people with BED compared to HCs. Patients with AN appear to have lower CRP levels compared to healthy controls. This could be a result of malnutrition or specific nutritional deficiencies. Due to the reduced CRP levels in AN, patients might be at risk for bacterial infections or developing autoimmune diseases, and clinicians might fail to notice an inflammatory process or an infection. In contrast, patients with BED were found to have higher CRP level than healthy controls which might be a consequence of an inflammatory response triggered by overeating, disordered eating patterns and the consumption of low-quality food during binges.</p>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"181 ","pages":"653-662"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142915106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Perceived gender discrimination in the workplace and onset of depressive symptoms in women: A population-based longitudinal analysis in South Korea.","authors":"Seong-Uk Baek, Jin-Ha Yoon","doi":"10.1016/j.jpsychires.2024.12.040","DOIUrl":"10.1016/j.jpsychires.2024.12.040","url":null,"abstract":"<p><strong>Background: </strong>Discrimination is a major cause of mental health problems; however, there is a limited understanding of the mental health consequences specifically associated with workplace gender discrimination (WGD). We explored the association between WGD and the onset of depressive symptoms among Korean female employees.</p><p><strong>Methods: </strong>This study included 3536 female employees (6223 observations) who participated in the Korean Longitudinal Survey of Women & Family (2014-2018). The respondents' perceptions of WGD were measured across six dimensions: hiring, promotion, wage, work assignments, training opportunities, and termination. The outcome was the onset of depressive symptoms after a 2-year follow-up assessed using the 10-item version of the Center for Epidemiological Studies-Depression Scale. To account for repeated measurements in each participant, we employed generalized estimating equations to estimate the risk ratios (RRs) and 95% confidence intervals (CIs).</p><p><strong>Results: </strong>Approximately 15-20% of female employees reported WGD across each dimension. The overall incidence rate of depressive symptoms during the study period was 9.6%. In the regression analysis, female employees who responded that they experienced WGD with respect to wages were more likely to develop depressive symptoms at follow-up (adjusted RR: 1.49; 95% CI: 1.09-2.04). The other dimensions of WGD did not show a clear association with the onset of depressive symptoms.</p><p><strong>Conclusion: </strong>WGD is an important risk factor for onset of depressive symptoms in women. Our study suggests that proactive policy interventions are required to promote gender equality in the workplace and protect mental well-being of female workers.</p>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"181 ","pages":"689-694"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142921881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Swikar Poudel, Sandro Sperandei, Andrew Page, Arianne Reis, Yi Guo, Sithum Munasinghe, Kathryn Worne, Rowena Saheb, Vlasios Brakoulias
{"title":"Trends and determinants of time spent in the emergency department among Australian hospital presenting self-harm cases.","authors":"Swikar Poudel, Sandro Sperandei, Andrew Page, Arianne Reis, Yi Guo, Sithum Munasinghe, Kathryn Worne, Rowena Saheb, Vlasios Brakoulias","doi":"10.1016/j.jpsychires.2024.12.003","DOIUrl":"10.1016/j.jpsychires.2024.12.003","url":null,"abstract":"<p><strong>Aims: </strong>Waiting time (WT) and length of stay (LOS) are important metrics used to assess service delivery in emergency departments (EDs), and have been associated with subsequent re-presentations in EDs. This study investigated socio-demographic and health service determinants of WT and LOS among hospital treated self-harm (SH) cases presenting to EDs in Australian based hospitals.</p><p><strong>Methods: </strong>This study employed a retrospective cohort study of all SH cases (N = 6203) presenting to public hospital EDs in the Western Sydney catchment area from January 2016 to December 2022. Cox proportional hazard models were used to analyse demographic and service factors related to WT and LOS in Australian hospitals along with a description of secular trends in WT and LOS.</p><p><strong>Results: </strong>Longer WT was evident for patients aged 15-64 than 0-14 years, non-admitted patients and patients arriving at the ED via transport other than ambulance whereas longer LOS was associated with older patients (65+ years). The inflow of non-SH cases to the ED did not have an impact on WT or LOS among SH cases. WT and LOS increased over time, particularly post the onset of the COVID-19 pandemic. The number of current self-harm cases receiving treatment in ED at the time of patient's arrival also increased WT and LOS.</p><p><strong>Conclusions: </strong>WT and LOS have increased, especially post the onset of the COVID-19 pandemic. These findings necessitate the urgent need for updated strategies to manage ED resources, and suggest initiatives relating to ED diversion where appropriate for patients presenting to hospital following SH.</p>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"181 ","pages":"365-372"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Inma Fernández, Óscar Vallina-Fernández, Sandra Alonso-Bada, Mar Rus-Calafell, Mercedes Paino
{"title":"Emotional regulation as a mediating variable between risk of psychosis and common mental health problems in adolescents.","authors":"Inma Fernández, Óscar Vallina-Fernández, Sandra Alonso-Bada, Mar Rus-Calafell, Mercedes Paino","doi":"10.1016/j.jpsychires.2024.11.058","DOIUrl":"10.1016/j.jpsychires.2024.11.058","url":null,"abstract":"<p><strong>Background: </strong>The main clinical high-risk of psychosis (CHRp) approaches are focused on core features of schizophrenia that might surface in the prodromal phases, mainly psychotic-like experiences (PLEs) (e.g., prodromal or schizotypal symptoms) or associated phenomena like basic symptoms or anomalous experiences of the self. Given that PLEs vary depending on distress levels, related common mental health problems, emotional regulation (ER) strategies and eventual clinical outcomes, exploring the heterogeneous nature of these PLEs and their psychological correlates could aid in distinguishing between subclinical and clinical psychotic experiences. The present study aims firstly to generate new evidence on the understanding of clinical relevance of PLEs and associated phenomena in a non-clinical representative sample of 1824 Spanish adolescents, according to their CHRp level (high/moderate/low). Secondly, we analyzed the possible mediating effect of three different emotional regulation strategies ((experiential avoidance (EA), cognitive reappraisal (CR) and emotional suppression (ES)) between PLEs and non-specific symptoms of depression, anxiety, stress, trauma related distress and substance use. Results showed that a more frequent use of EA and ES resulted in a higher CHRp, with no differences in the use of CR. In addition, EA emerged as a significant mediating factor between CHRp and the development of emotional symptoms and substance use. Emotion regulation strategy may account for heterogeneity in PLE outcomes. The use of EA as a coping strategy for their PLEs in adolescents with CHRp may facilitate the development of common mental health problems such as anxiety, depression or cannabis use pathologies. Helping adolescents at CHRp to use non-avoidant coping strategies may be indicated if their preventive effects are demonstrated.</p>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"181 ","pages":"273-281"},"PeriodicalIF":3.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}