Journal of psychiatric research最新文献

{"title":"An exploration of exaggerated fears of identity theft in hoarding disorder","authors":"Blaise L. Worden,&nbsp;Hannah C. Levy","doi":"10.1016/j.jpsychires.2025.05.043","DOIUrl":"10.1016/j.jpsychires.2025.05.043","url":null,"abstract":"<div><h3>Introduction</h3><div>Individuals with hoarding symptoms often report laborious routines of reviewing and destroying paperwork prior to discarding, citing fears of identity theft if personal information is discarded. While fears of identity theft seem likely to be elevated in hoarding disorder, it is unclear if these fears are elevated beyond what is normative for older adults, and whether such fears may be related to third factors.</div></div><div><h3>Method</h3><div>In the current study we sought to explore whether fears of identity theft were higher among 103 individuals high in hoarding symptoms as compared with 59 non-hoarding controls. We also sought to examine whether higher fears of identity theft were attributable to third factors such as increased past exposure to identity theft victimization, respondent age, race, or higher perfectionism scale scores.</div></div><div><h3>Results</h3><div>Findings suggested that individuals in the hoarding group reported higher fears of identity theft, and higher rates of knowing individuals who had been victimized, but did not report significantly higher history of personal victimization. Other variables such as age, perfectionism subscale scores, and co-occurring anxiety and depression symptoms did not appear to explain the relationship between hoarding and increased fears of identity theft, suggesting it may have some specificity to hoarding.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"188 ","pages":"Pages 140-147"},"PeriodicalIF":3.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144169985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early improvement of psychopathological symptoms with add-on repetitive transcranial magnetic stimulation treatment as the key contributor to improving remission in schizophrenia","authors":"Qiang Hu ,&nbsp;Xiong Jiao ,&nbsp;XiaoChen Tang ,&nbsp;YeGang Hu ,&nbsp;LiHua Xu ,&nbsp;YanYan Wei ,&nbsp;HuiRu Cui ,&nbsp;YingYing Tang ,&nbsp;Tao Chen ,&nbsp;HaiChun Liu ,&nbsp;ZiXuan Wang ,&nbsp;Jin Gao ,&nbsp;LingYun Zeng ,&nbsp;ZhengHui Yi ,&nbsp;ChunBo Li ,&nbsp;JiJun Wang ,&nbsp;TianHong Zhang","doi":"10.1016/j.jpsychires.2025.05.045","DOIUrl":"10.1016/j.jpsychires.2025.05.045","url":null,"abstract":"<div><div>Early improvement with antipsychotic treatment is thought to be important in patients with first-episode schizophrenia(FES); however, no study has examined the contribution of add-on repetitive transcranial magnetic stimulation (rTMS). This study is aimed to investigate the efficacy and early improvement of rTMS in FES and to identify the relationship between initial symptom reduction and late response. A total of 105 patients with FES were randomly assigned to two groups: active rTMS group (n = 60) and sham rTMS group (n = 45), with existing olanzapine (10–20 mg/day) combined with 20 sessions of 1Hz active/sham rTMS over the right orbitofrontal cortex (20min/session, 5times/week). The Positive and Negative Syndrome Scale(PANSS) was used as the main tool to evaluate the clinical symptoms of patients at baseline, week-2, and week-8. Early improvement was defined as an improvement in PANSS total score at week 2. Significant improvements in clinical symptoms(PANSS total, positive[PANSS-P], negative[PANSS-N], and general psychopathological symptoms[PANSS-G]) were found in both the rTMS and sham groups. Moreover, a repeated-measures general linear model showed the decrease from baseline in PANSS-total(group × visit, <em>F</em> = 9.906, <em>p</em> &lt; 0.001), PANSS-N(group × visit, <em>F</em> = 4.108, <em>p</em> = 0.020), and PANSS-G(group × visit, <em>F</em> = 12.095, <em>p</em> &lt; 0.001) at week 8 were significant in the active rTMS group but not in the sham group. The active rTMS group had significant early improvements in PANSS-total(<em>z</em> = 3.348, <em>p</em> = 0.001), PANSS-N(<em>z</em> = 2.222, <em>p</em> = 0.026) and PANSS-G(<em>z</em> = 2.624, <em>p</em> = 0.009), compared with the sham group. Early improvements were significantly related to the 8-week improvements. Add-on rTMS treatment as a supplement to antipsychotics could potentially increase the efficacy of early improvements and improve the ultimate remission in patients with FES.</div></div><div><h3>Clinical trial registration</h3><div>Chinese Clinical Trial Register Center (<span><span>http://www.chictr.org.cn/</span><svg><path></path></svg></span>)</div></div><div><h3>Identifier</h3><div>ChiCTR2000041106.</div></div><div><h3>Registered</h3><div>December 17, 2020.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"188 ","pages":"Pages 64-73"},"PeriodicalIF":3.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144147245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attentional disengagement difficulties toward game-related social reward and avoidance toward real-life social reward among individuals with Internet gaming disorder","authors":"Xiaoyu Wang ,&nbsp;Jingyi Yang ,&nbsp;Jinbo He","doi":"10.1016/j.jpsychires.2025.05.041","DOIUrl":"10.1016/j.jpsychires.2025.05.041","url":null,"abstract":"<div><div>Individuals with Internet Gaming Disorder (IGD) exhibit behaviors of immersion in game social interactions and detachment from real-life social interactions. Social Motivation Theory posits that social rewards incentivize social activities, while impairments in social reward processing may lead to such behaviors. Moreover, attentional bias plays a crucial role in reward processing. However, no studies have examined attentional bias toward social rewards in individuals with IGD. Therefore, this study utilized a dot-probe paradigm to compare attentional bias toward game-related social rewards (GR) and real-life social rewards (RR) between 30 individuals with IGD and 31 healthy controls (HC) and further explored attentional vigilance (early-stage) and disengagement difficulties/avoidance (later-stage). The results indicated that (1) individuals with IGD exhibited higher attentional bias toward GR than RR. (2) Attentional bias in individuals with IGD occurred in later stages, characterized by attentional disengagement difficulties for GR and attentional avoidance for RR. (3) The degree of attentional disengagement difficulties for GR and attentional avoidance for RR in individuals with IGD was positively correlated with the severity of IGD. The results suggest that immersion in gaming social interactions and disconnection from real-life social interactions in individuals with IGD may be related to difficulties in disengaging from GR and avoiding RR in later stages of attentional bias. This study reveals the mechanisms underlying the different patterns of social activities of individuals with IGD in both gaming and real-life contexts from the perspective of attentional bias toward social rewards.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"189 ","pages":"Pages 244-251"},"PeriodicalIF":3.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144306237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depressive symptoms interact with CSF levels of p-tau in predicting cognitive performance in the early stages of Parkinson's disease","authors":"Ainara Jauregi-Zinkunegi ,&nbsp;Lucia Ronconi ,&nbsp;Davide Bruno ,&nbsp;Elisa Di Rosa","doi":"10.1016/j.jpsychires.2025.05.038","DOIUrl":"10.1016/j.jpsychires.2025.05.038","url":null,"abstract":"<div><div>Amyloid-β deposition and tau pathology are suggested to play a role in the emergence of depressive symptoms and cognitive decline in Parkinson's disease (PD). Additionally, studies have reported an association between presence of the APOE4 allele and poorer cognition in PD. The present study aims to investigate whether amyloid-β, tau pathology and APOE4 carrier status interact with depressive symptoms in predicting global cognition in PD.</div><div>We analysed data from 348 persons with PD (PwPD) and 160 healthy controls (HCs). Linear mixed effects regression analyses were conducted to examine if CSF levels of Aβ42 and p-tau, and APOE4 carrier status did interact with depressive symptoms, as assessed by the Geriatric Depression Scale (GDS), in predicting cognition performance, as measured by Montreal Cognitive Assessment Test (MoCA) scores, over three years.</div><div>Results of a first linear regression model conducted considering both PwPD and HC indicated that MoCA scores were significantly predicted by GDS, as well as by the interaction between GDS and p-tau, Group and p-tau, and between Group, p-tau and GDS. Results of the models conducted in the two groups separately indicated that, while in HC MoCA scores were predicted by age and time only, a significant interaction between GDS and CSF levels of p-tau emerged as a predictor of MoCA scores in PwPD. Specifically, post hoc analysis revealed a negative association between CSF levels of p-tau and cognitive performance that was significant only in PwPD with the highest GDS scores.</div><div>Taken together, results of this study confirm that, in early stages of PD, depressive symptoms interact with CSF levels of p-tau in predicting cognitive performance. Findings highlight the importance of assessing and treating depression in PwPD as early as possible, as it might reduce the likelihood of future cognitive decline.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"188 ","pages":"Pages 87-93"},"PeriodicalIF":3.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144147247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk and protective factors that distinguish United States veterans with a history of suicidal ideation and suicide attempt","authors":"David P. Cenkner,&nbsp;Alyson K. Zalta","doi":"10.1016/j.jpsychires.2025.05.059","DOIUrl":"10.1016/j.jpsychires.2025.05.059","url":null,"abstract":"<div><div>Many risk and protective factors for suicidal thoughts and behaviors among United States veterans are known. However, factors differentiating veterans who endorse suicidal ideation to veterans who engage in suicide attempts are understudied. The current study examined factors that distinguished these two groups using the Military Health and Well-Being Project, an online dataset of 1495 veterans that oversampled for female and Black veterans. Veterans (<em>N</em> = 620; 39 % female; 15 % Black) were grouped by those who endorsed a history of suicidal thoughts (<em>n</em> = 548) or suicide attempts (<em>n</em> = 72). Independent samples <em>t</em>-tests were conducted to examine differences in individual risk and protective factors. A binary logistic regression was conducted to examine which factors uniquely distinguished between veterans with past ideation and veterans with past attempts. Compared to veterans with past ideation, those with past attempts had higher scores on moral injury (<em>d</em> = −0.80; <em>p</em> &lt; .001), substance use (<em>d</em> = −0.72; <em>p</em> &lt; .001), and loneliness (<em>d</em> = −0.62; <em>p</em> &lt; .001) and lower scores on meaning and purpose in life (<em>d</em> = 0.89; <em>p</em> &lt; .001) and social support (<em>d</em> = 0.61; <em>p</em> &lt; .001). When collectively examined, female gender (OR = 2.37), endorsing lower meaning and purpose in life (OR = 0.55) and endorsing greater substance use (OR = 1.81) were unique predictors of attempting suicide. Findings suggest the importance of assessing and targeting meaning and purpose in life and substance use in veterans endorsing suicidal ideation to potentially prevent the transition to attempting suicide.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"188 ","pages":"Pages 126-132"},"PeriodicalIF":3.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144169983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability and validity of the Japanese version of the Misophonia Questionnaire (MQ)","authors":"Chihiro Itoi ,&nbsp;Yuta Ujiie ,&nbsp;Makio Kashino","doi":"10.1016/j.jpsychires.2025.05.040","DOIUrl":"10.1016/j.jpsychires.2025.05.040","url":null,"abstract":"<div><div>The Misophonia Questionnaire (MQ) is a self-report measure designed to assess misophonia symptoms. It has been validated in various languages and across different samples. However, no prior research has validated the MQ in Japanese samples. This study aimed to develop a Japanese version of the Misophonia Questionnaire (MQ-J) and examine its psychometric properties. This study confirmed the score distribution, internal consistency, and factor structure in a Japanese sample via an online survey. We also compared the MQ-J scores between individuals with misophonia symptoms and control participants. Additionally, we examined the relationships between the MQ-J and sensory processing issues, obsessive-compulsive tendencies, anxiety, depressive symptoms, and difficulties in daily life. Results demonstrated excellent internal consistency (α = .93) for the MQ-J, with significantly higher scores in the misophonia group compared with the control group. Furthermore, significant positive correlations were observed with sensory processing problems, obsessive-compulsive tendencies, anxiety, depressive symptoms, and difficulties in daily life. These findings supported the validity and reliability of the MQ-J. Hence, the MQ-J was a valuable tool for assessing misophonia symptoms in Japanese adults.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"188 ","pages":"Pages 133-139"},"PeriodicalIF":3.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144169984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of bilateral high-definition γ-tACS on negative symptoms and mismatch negativity in schizophrenia","authors":"Wen Liu ,&nbsp;Li Wan ,&nbsp;Yaqun Chen ,&nbsp;Longcai Fei ,&nbsp;Huanzhong Liu","doi":"10.1016/j.jpsychires.2025.05.056","DOIUrl":"10.1016/j.jpsychires.2025.05.056","url":null,"abstract":"<div><h3>Background</h3><div>At present, there is a lack of good treatment methods for the negative symptoms of schizophrenia. Previous studies have suggested that high-definition transcranial alternating current stimulation (HD tACS) in the dorsolateral prefrontal cortex (DLPFC) can significantly improve negative symptoms and that γ oscillation may also be effective for treating negative symptoms. The aim of our study was to investigate the therapeutic effect of HD γ-tACS on the negative symptoms of schizophrenia. Active auditory mismatch negativity (MMN) was introduced as neurobiological evidence to verify the intervention effect of tACS on schizophrenia.</div></div><div><h3>Methods</h3><div>A total of 53 patients with schizophrenia mainly with negative symptoms were enrolled in our study. Twenty-seven patients were divided into a real group, which was based on 60 Hz stimulation, 15 min on the unilateral side, for 10 consecutive working days, and 26 patients were divided into a sham group to receive tACS intervention. At baseline and after the intervention, the clinical and behavior scale measurements and EEG data collection under the active auditory oddball paradigm were performed in the two groups, and the differences between the two groups were compared and analysed.</div></div><div><h3>Results</h3><div>1. At baseline, there was no significant difference in the active MMN (MMN/P3a complex) amplitude between the two groups. 2. After tACS intervention, the active MMN amplitudes of the Fz, FCz, Cz, CPz and Pz channels in the central frontoparietal lobe of the real tACS group increased significantly. 3. Negative symptoms were significantly reduced in the real tACS group positive and negative syndrome scale (PANSS) negative symptom subscale score. 4. Regression analysis revealed that in the Fz channel, the change in MMN was moderately positively correlated with the reduction in negative symptom scores.</div></div><div><h3>Conclusion</h3><div>γ-tACS in the bilateral dlPFC can significantly improve the negative symptoms of patients with schizophrenia, and the amplitude of active MMN in the frontoparietal region is significantly increased after intervention. To some extent, the greater the improvement in active MMN after intervention compared with baseline, the more obvious the improvement in clinical negative symptoms. This study provides a reference for tACS therapy to improve negative symptoms in patients with schizophrenia.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"188 ","pages":"Pages 43-51"},"PeriodicalIF":3.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144139067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Calls with suicidality and psychological distress to a national helpline during the COVID-19 pandemic","authors":"Shiri Daniels ,&nbsp;Hadas Yeshayahu ,&nbsp;Gil Zalsman ,&nbsp;Sahar Yihia ,&nbsp;Ella Sarel-Mahlev ,&nbsp;Joy Benatov","doi":"10.1016/j.jpsychires.2025.05.054","DOIUrl":"10.1016/j.jpsychires.2025.05.054","url":null,"abstract":"<div><div>This study examines the psychological distress and suicide-related calls to Israel's national crisis helpline (ERAN) in the aftermath of the COVID-19 pandemic, evaluating the impact of COVID-19 public health measures, including lockdowns and vaccination rollouts. The analysis, covering over a million calls, investigating trends in call volume associated with policy shifts. Findings indicate an initial peak in distress calls, which gradually declined, stabilizing after vaccines became available. Suicide-related calls increased at a slower rate and later dropped, following vaccine rollout. Lockdowns were correlated with heightened general distress, but not with an increase in suicide-related calls.</div><div>The findings highlight the importance of continuous monitoring and support for populations at risk of suicide, as suicidal tendencies can emerge gradually, lagging after the emotional distress. These results underscore the critical role of public health measures in mitigating mental health outcomes during national health crises, potentially offering policymakers valuable insights for future pandemic response planning.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"188 ","pages":"Pages 57-63"},"PeriodicalIF":3.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144139066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drug-related suicidal ideation in the K-12 population: a real-world pharmacovigilance study of the FDA adverse event reporting system (FAERS) database","authors":"Yaxin Ju ,&nbsp;Yuan Liu ,&nbsp;Li Tan ,&nbsp;Li Su","doi":"10.1016/j.jpsychires.2025.05.029","DOIUrl":"10.1016/j.jpsychires.2025.05.029","url":null,"abstract":"<div><h3>Objective</h3><div>The K-12 population refers to individuals, primarily aged 6–17, from kindergarten through 12th grade. Drug-related suicidal ideation (SI) in the K-12 population is a major concern. This study aims to identify medications linked to increased SI risk in the K-12 population using the FDA Adverse Event Reporting System (FAERS) database.</div></div><div><h3>Methods</h3><div>We extracted cases of SI in individuals aged 6–17 years where medications were the primary suspect (PS) from the FAERS database, spanning from the first quarter of 2004 to the third quarter of 2023. We conducted descriptive analysis, disproportionality analysis, and subgroup analysis.</div></div><div><h3>Results</h3><div>Our analysis included 4,779 valid cases; 52.75 % were male and 45.66 % were female. The predominant age group was 15–17 years, accounting for 43.92 % of cases. The peak year for case reports was 2019. Montelukast was the most common drug. The four most common indications included attention deficit hyperactivity disorder, depression, acne, and asthma. Disproportionality analysis highlighted 21 drugs as potentially associated with increased SI risk, with esketamine displaying the highest signal (Reporting Odds Ratio, ROR = 103.49). Subgroup analysis identified eleven drugs with elevated risk signals in both genders. Montelukast presented the highest signal in males (ROR = 12.64), and esketamine in females (ROR = 129.50). Cumulatively, the incidence of SI within 90 and 360 days was 51.6 % and 76.9 % in males, and 58.8 % and 85.3 % in females, respectively.</div></div><div><h3>Conclusion</h3><div>This study provides evidence of potential SI risk associated with specific medications in the K-12 population. Further research is necessary to confirm these findings.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"188 ","pages":"Pages 1-9"},"PeriodicalIF":3.7,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the benefits of art therapy for anxiety and depression in women with breast cancer: A meta-analytical systematic review","authors":"Tangsen Huang,&nbsp;Xiangdong Yin","doi":"10.1016/j.jpsychires.2025.05.027","DOIUrl":"10.1016/j.jpsychires.2025.05.027","url":null,"abstract":"<div><h3>Objective</h3><div>This meta-analysis examined the impact of art therapy on depression and anxiety in women with breast cancer.</div></div><div><h3>Background</h3><div>Many breast cancer patients experience significant psychological distress, particularly anxiety and depression, which can diminish their quality of life. While pharmacological treatments are commonly used, art therapy is gaining attention as a promising alternative intervention.</div></div><div><h3>Methods</h3><div>A comprehensive search of Web of Science, PubMed, and Scopus was conducted up to October 3, 2024, to identify relevant studies. Studies were eligible if they were randomized controlled trials, quasi-randomized trials, or controlled clinical trials involving women diagnosed with breast cancer who received art therapy targeting psychosocial outcomes. Art therapy modalities included music therapy, dance movement therapy, painting, drawing, and self-book© art therapy. The quality of included studies was evaluated using the Cochrane risk of bias tool.</div></div><div><h3>Results</h3><div>Seventeen studies met the inclusion criteria, comprising 617 participants in the intervention group and 620 in the control group. The duration of interventions ranged from 1 week to 24 months. The overall pooled effect size for art therapy's impact on anxiety was −1.594 (95 % CI, −2.405 to −0.784), and for depression, −0.771 (95 % CI, −1.347 to −0.195). When studies with high risk of bias were excluded, the effect sizes remained significant for both anxiety (−1.430; 95 % CI, −1.665 to −1.195) and depression (−1.229; 95 % CI, −2.280 to −0.177), with a corresponding reduction in heterogeneity. Subgroup analyses explored the role of study quality, participant age, and intervention duration in the variability of effect sizes.</div></div><div><h3>Conclusion</h3><div>Art therapy significantly reduces anxiety and depression among women with breast cancer. These findings support the integration of art-based interventions into psychosocial oncology care.</div></div>","PeriodicalId":16868,"journal":{"name":"Journal of psychiatric research","volume":"189 ","pages":"Pages 403-414"},"PeriodicalIF":3.7,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144501277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}