Exploring the interrelations of obsessions, compulsions, and health: the mediating role of psychotic symptoms in individuals with obsessive-compulsive disorder

IF 3.2 2区医学 Q1 PSYCHIATRY

Journal of psychiatric research Pub Date : 2025-09-17 DOI:10.1016/j.jpsychires.2025.09.022

Gema Aonso-Diego , Pamela Parada-Fernández , Laura Mendo , Laura Macía , Ana Estévez , Claudio Maruottolo

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引用次数: 0

Abstract

Background

Despite the high comorbidity between obsessive-compulsive and psychotic symptoms, little is known about its impact on the health of individuals with obsessive-compulsive disorder (OCD). This study aimed to 1) explore the prevalence of psychotic symptoms in individuals with OCD, and 2) examine the mediating role of psychotic symptoms in the relationship between obsessive-compulsive symptoms and overall health.

Methods

This study included 102 participants undergoing treatment for OCD (M_age = 42.33, SD = 14.40, 52.9 % female). Structural equation modeling was employed to assess whether psychotic symptoms mediated the relationship between obsessive-compulsive symptoms and health outcomes.

Results

Among participants with OCD (from mild to severe), 53.9 % exhibited positive psychotic symptoms, 74.7 % presented negative psychotic symptoms, and 83.5 % showed depressive psychotic symptoms. A significant correlation was found between OCD symptoms and psychotic symptoms (r ranging from .338 to .512). Structural equation modeling indicated that psychotic symptoms fully mediated the relationship between compulsions and health.

Conclusions

Understanding the intricate relationship between OCD and psychotic symptoms remains a critical challenge in mental health research and clinical practice. Enhanced insights into this connection could facilitate more precise diagnoses and allow for more personalized treatments.

查看原文本刊更多论文

探索强迫、强迫和健康的相互关系：精神病症状在强迫症患者中的中介作用。

背景：尽管强迫症和精神病性症状之间有很高的合并症，但其对强迫症（OCD）患者健康的影响知之甚少。本研究旨在探讨强迫症患者精神病性症状的患病率，以及精神病性症状在强迫症与整体健康关系中的中介作用。方法：本研究纳入102名接受强迫症治疗的参与者（Mage = 42.33, SD = 14.40, 52.9%为女性）。采用结构方程模型评估精神病性症状是否介导强迫症状与健康结局之间的关系。结果：在强迫症患者中（从轻到重），53.9%表现为阳性精神病症状，74.7%表现为阴性精神病症状，83.5%表现为抑郁性精神病症状。在强迫症症状和精神病症状(r范围从。338到0.512)。结构方程模型表明，精神症状完全介导强迫与健康的关系。结论：理解强迫症与精神病症状之间的复杂关系仍然是心理健康研究和临床实践中的一个关键挑战。加深对这种联系的了解可以促进更精确的诊断，并允许更个性化的治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of psychiatric research 医学-精神病学

CiteScore

7.30

自引率

2.10%

发文量

622

审稿时长

130 days

期刊介绍： Founded in 1961 to report on the latest work in psychiatry and cognate disciplines, the Journal of Psychiatric Research is dedicated to innovative and timely studies of four important areas of research: (1) clinical studies of all disciplines relating to psychiatric illness, as well as normal human behaviour, including biochemical, physiological, genetic, environmental, social, psychological and epidemiological factors; (2) basic studies pertaining to psychiatry in such fields as neuropsychopharmacology, neuroendocrinology, electrophysiology, genetics, experimental psychology and epidemiology; (3) the growing application of clinical laboratory techniques in psychiatry, including imagery and spectroscopy of the brain, molecular biology and computer sciences;