Journal of Pesticide Science最新文献_第4页

Inhibition of chitin synthesis by 5-benzoylamino-3-phenylisoxazoles with various substituents at two benzene rings and their larvicidal activity. 两苯环上不同取代基的5-苯甲酰氨基-3-苯基异恶唑对几丁质合成的抑制作用及其杀虫活性。

IF 1.8 4区农林科学

Journal of Pesticide Science Pub Date : 2025-08-20 DOI: 10.1584/jpestics.D25-040

Kotaro Mori, Masahiro Miyashita, Soichirou Mori, Norio Shibata, Mitsunori Ikeguchi, Yoshiaki Nakagawa

{"title":"Inhibition of chitin synthesis by 5-benzoylamino-3-phenylisoxazoles with various substituents at two benzene rings and their larvicidal activity.","authors":"Kotaro Mori, Masahiro Miyashita, Soichirou Mori, Norio Shibata, Mitsunori Ikeguchi, Yoshiaki Nakagawa","doi":"10.1584/jpestics.D25-040","DOIUrl":"10.1584/jpestics.D25-040","url":null,"abstract":"N-(3-Phenylisoxazol-5-yl)benzamides (5-benzoylamino-3-phenylisoxazoles: IOXs) with various substituents at two benzene rings were synthesized, and the chitin synthesis inhibition was measured in the cultured integumentary system of Chilo suppressalis. Larvicidal effects against C. suppressalis and Spodoptera litura were also examined, and the larvicidal activity in terms of the 50% lethal dose (LD50) was determined for some compounds. Among IOXs with various substituents at the benzoyl moiety, 2,6-difluoro-substituted (2,6-F2) benzoyl analogs showed the highest chitin synthesis activity. The larvicidal activities against C. suppressalis and S. litura were 1/138 and 1/35 that of diflubenzuron, a representative benzoylphenylurea-type insecticide, respectively. In a further study, 2,6-F2 benzoyl analogs with various substituents at the phenyl moiety, such as Br, CF3, CN, OEt, Ph, and alkyls (CH3, Et, i-Pr, n-Bu, and t-Bu), were synthesized, and their chitin synthesis inhibition in the Chilo integument and their larvicidal activity against S. litura were quantitatively measured. The introduction of bulky CF3 and t-Bu at the phenyl moiety of 2,6-F2 benzoyl analog favorably enhanced the larvicidal activity against S. litura.","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"50 3","pages":"81-86"},"PeriodicalIF":1.8,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405007/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of the insecticide oxazosulfyl. 杀虫剂恶唑磺酰的研制。

IF 1.8 4区农林科学

Journal of Pesticide Science Pub Date : 2025-08-20 DOI: 10.1584/jpestics.J25-02

Mai Ito, Yoshihiko Nokura, Masaki Takahashi, Masashi Kamezaki, Emiko Sakamoto, Shinya Nishimura

{"title":"Development of the insecticide oxazosulfyl.","authors":"Mai Ito, Yoshihiko Nokura, Masaki Takahashi, Masashi Kamezaki, Emiko Sakamoto, Shinya Nishimura","doi":"10.1584/jpestics.J25-02","DOIUrl":"10.1584/jpestics.J25-02","url":null,"abstract":"Oxazosulfyl, a novel insecticide originally discovered and developed by Sumitomo Chemical Co., Ltd., belongs to a new chemical class, the sulfyl group, structurally characterized by its ethylsulfonyl moiety. It exhibits excellent control against a broad range of major rice insect pests, including Coleoptera, Hemiptera, Lepidoptera, and Orthoptera, through nursery-box application. With a novel structural backbone and mode of action, this insecticide is classified by the Insecticide Resistance Action Committee as the sole member of novel code 37, vesicular acetylcholine transporter inhibitor. A substantial number of field studies in rice paddy fields have demonstrated that oxazosulfyl, registered in Japan in April 2021 as ALLES® granules, is highly effective against populations that have developed reduced sensitivity or resistance to existing insecticides. Given these favorable properties, oxazosulfyl is expected to contribute to the management of insecticide resistance, the reduction of agricultural chemical use, labor savings, and sustainable agriculture as a next-generation insecticide.","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"50 3","pages":"96-101"},"PeriodicalIF":1.8,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of capsaicin on voltage-gated sodium channels with kdr mutation from German cockroaches (Blattella germanica). 辣椒素对德国小蠊kdr突变电压门控钠通道的影响

IF 1.8 4区农林科学

Journal of Pesticide Science Pub Date : 2025-08-20 DOI: 10.1584/jpestics.D25-023

Masashi Kamezaki, Hisashi Nishiwaki

{"title":"Effect of capsaicin on voltage-gated sodium channels with kdr mutation from German cockroaches (Blattella germanica).","authors":"Masashi Kamezaki, Hisashi Nishiwaki","doi":"10.1584/jpestics.D25-023","DOIUrl":"10.1584/jpestics.D25-023","url":null,"abstract":"Capsaicin inhibits the current flow in the voltage-gated sodium channels (VGSCs) of mammals and insects. The aim of the present study was to elucidate capsaicin toxicity in pyrethroid-susceptible and knockdown resistant (kdr; with reduced pyrethroid sensitivity) strains of the German cockroach (Blattella germanica) and its effects on VGSCs carrying the kdr mutation. Injection tests revealed that adult cockroaches from susceptible and kdr strains exhibited sluggish movement and paralysis upon abdominal capsaicin administration, consistent with its inhibitory effect on VGSC currents. The LD50 values of capsaicin were 16 and 36 µg per insect for the susceptible and kdr strains, respectively, yielding a resistance ratio of 2.3. Two-electrode voltage clamp assays showed that the EC50 values for the capsaicin-mediated inhibition of VGSC currents were 4.27 and 9.19 µM for susceptible and kdr mutant channels, respectively, yielding a resistance ratio of 2.2. The findings indicate that capsaicin retains inhibitory activity against insect VGSCs even in the presence of kdr mutations.","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"50 3","pages":"74-80"},"PeriodicalIF":1.8,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advantages of ethylene glycol diacetate as a potential solvent for herbicide formulations. 二乙酸乙二醇作为除草剂制剂潜在溶剂的优点。

IF 1.5 4区农林科学

Journal of Pesticide Science Pub Date : 2025-05-20 DOI: 10.1584/jpestics.D24-051

Menghan Li, Longfei Jin, Bin Liu, Yifang Qian, Haofu Hu, Xin Wang, Yang Zhang, Wenping Xu

{"title":"Advantages of ethylene glycol diacetate as a potential solvent for herbicide formulations.","authors":"Menghan Li, Longfei Jin, Bin Liu, Yifang Qian, Haofu Hu, Xin Wang, Yang Zhang, Wenping Xu","doi":"10.1584/jpestics.D24-051","DOIUrl":"10.1584/jpestics.D24-051","url":null,"abstract":"Emulsifiable concentrates and oil suspensions are typical pesticide formulations. Many pesticides on the market use aromatic hydrocarbons as solvents. However, studies have revealed their potential risks to humans and the environment. Ethylene glycol diacetate (EGDA) is a low-toxicity and eco-friendly solvent with low utilization in pesticides. This study explores EGDA's potential to replace xylene. Results indicate that EGDA formulations enhance droplet adhesion to leaves, boosting pesticide efficiency. They exhibit lower surface tension and contact angles, with a 24%-40% increase in leaf retention. Bioassays show that 15% cyhalofop-butyl EC and 10% nicosulfuron OF with EGDA offer weed control that is superior to xylene-based formulations by 9.1%-30.5% in greenhouses and 4.8%-6.7% in fields. Xylene preparations are 2-3 times more cytotoxic to human bronchial cells than EGDA-based ones. Thus, EGDA is a promising pesticide solvent, outperforming traditional aromatic solvents in environmental friendliness and reducing adverse effects.","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"50 2","pages":"31-39"},"PeriodicalIF":1.5,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12256704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144637290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biological efficacy of polyoxin D in crop protection. 多毒素D在作物保护中的生物学功效。

IF 1.5 4区农林科学

Journal of Pesticide Science Pub Date : 2025-05-20 DOI: 10.1584/jpestics.D24-055

Kyuya Suda, Shin-Ichiro Kochi

引用次数: 0

Assessing α-galactosidase OmAGAL2 inhibitors and their impact on germination and sugar profiles in Orobanche minor. α-半乳糖苷酶OmAGAL2抑制剂及其对小山核桃萌发和糖谱的影响

IF 1.5 4区农林科学

Journal of Pesticide Science Pub Date : 2025-05-20 DOI: 10.1584/jpestics.D25-005

Masahiro Onitsuka, Takatoshi Wakabayashi, Takumi Ogawa, Yukihiro Sugimoto, Daisaku Ohta, Atsushi Okazawa

{"title":"Assessing α-galactosidase OmAGAL2 inhibitors and their impact on germination and sugar profiles in Orobanche minor.","authors":"Masahiro Onitsuka, Takatoshi Wakabayashi, Takumi Ogawa, Yukihiro Sugimoto, Daisaku Ohta, Atsushi Okazawa","doi":"10.1584/jpestics.D25-005","DOIUrl":"10.1584/jpestics.D25-005","url":null,"abstract":"Root parasitic weeds from the Orobanche genus significantly damage crop production in African and European countries. Previous studies identified the metabolism of planteose, a storage trisaccharide in root parasitic weeds, as a potential control target. In Orobanche minor, α-galactosidase OmAGAL2 hydrolyzes planteose into sucrose upon perceiving germination stimulant strigolactones. Subsequently, invertases break down sucrose into glucose and fructose, essential for germination. This study screened chemical libraries to identify inhibitors against OmAGAL2-mCherry, secreted from transgenic tobacco BY-2 cells. Two inhibitors, 82-G8 and 85-B10, which significantly reduced the OmAGAL2 activity to less than 70% of the control, were evaluated for their impact on O. minor germination and sugar profiles. Results showed that OmAGAL2 inhibitors suppressed O. minor radicle elongation by inhibiting planteose metabolism, with effects more pronounced when applied at the start of conditioning rather than during germination stimulation. Further structural optimization could yield a novel class of chemicals for controlling Orobanche spp.","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"50 2","pages":"40-46"},"PeriodicalIF":1.5,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12246499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and herbicidal activity of C5-substituted cinmethylin analogs. c5取代的五甲基林类似物的合成及其除草活性。

IF 1.5 4区农林科学

Journal of Pesticide Science Pub Date : 2025-05-20 DOI: 10.1584/jpestics.D24-056

Narihito Ogawa, Kakeru Hasegawa, Masaru Kawakami, Chihiro Uematsu, Tatsuya Hirano, Yusuke Mitani, Akihito Ootaka

引用次数: 0

Ovicidal activity of adulticidal insecticides against the invasive wood borer Aromia bungii. 杀成虫剂对入侵木蠹蛾的杀卵活性。

IF 1.5 4区农林科学

Journal of Pesticide Science Pub Date : 2025-02-20 DOI: 10.1584/jpestics.D24-050

Yuichi Yamamoto, Shuji Kaneko

{"title":"Ovicidal activity of adulticidal insecticides against the invasive wood borer Aromia bungii.","authors":"Yuichi Yamamoto, Shuji Kaneko","doi":"10.1584/jpestics.D24-050","DOIUrl":"10.1584/jpestics.D24-050","url":null,"abstract":"The development of preventive methods against the invasive wood-boring beetle Aromia bungii, which infests Rosaceae trees, is required in Japan. We investigated the effect on eggs of several commercial insecticides whose active ingredients are registered to kill A. bungii adults or larvae by tree injection or spray. The ovicidal activity was evaluated using the corrected egg hatch rates based on the control (distilled water) after dipping pieces of cardboard, on which eggs were deposited, in liquid insecticide solutions for 10 sec. The egg-dipping tests revealed highly effective ovicidal activity in the following insecticides: more than 8000 ppm for fenitrothion, 1000 ppm for acetamiprid, 400 ppm for clothianidin, and 500 ppm for dinotefuran (corrected egg-hatch rates of approximately less than 5%). In terms of current registration in Japan, only fenitrothion (SUMIPAIN emulsion) and acetamiprid (MATSUGREEN liquid solution 2) by trunk spraying during the A. bungii reproductive period are adulticidal insecticide candidates with preventive potential through incidental ovicidal activity.","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"50 1","pages":"1-8"},"PeriodicalIF":1.5,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11911499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research and development of an insecticide, afidopyropen. 研究和开发杀虫剂 afidopyropen。

IF 1.5 4区农林科学

Journal of Pesticide Science Pub Date : 2025-02-20 DOI: 10.1584/jpestics.J25-01

Ryo Horikoshi, Kimihiko Goto, Masaaki Mitomi, Toshiaki Sunazuka, Satoshi Ōmura

引用次数: 0

Erratum. 勘误表。

IF 1.5 4区农林科学

Journal of Pesticide Science Pub Date : 2025-02-20 DOI: 10.1584/jpestics.C25-01

引用次数: 0