Dimesulfazet, a novel rice paddy herbicide, is an inhibitor of very long-chain fatty acid biosynthesis

IF 1.5 4区农林科学 Q2 ENTOMOLOGY

Journal of Pesticide Science Pub Date : 2024-04-27 DOI:10.1584/jpestics.d23-036

Takamasa Furuhashi, Masato Otani, Mami Iwasa

{"title":"Dimesulfazet, a novel rice paddy herbicide, is an inhibitor of very long-chain fatty acid biosynthesis","authors":"Takamasa Furuhashi, Masato Otani, Mami Iwasa","doi":"10.1584/jpestics.d23-036","DOIUrl":null,"url":null,"abstract":"Dimesulfazet can control annual and perennial sedges in rice paddies. Here we assessed its mode of action. We performed a phenotype assay of Arabidopsis, conducted a metabolomic analysis of Echinochloa crus-galli, and analyzed the endogenous concentration of very long-chain fatty acids (VLCFAs) in Schoenoplectiella juncoides. Dimesulfazet treatment caused curling and greening symptoms in the leaves and fiddlehead-like symptoms in the inflorescences of Arabidopsis. These symptoms were visually indistinguishable from those caused by flufenacet and benfuresate, which belong to Herbicide Resistance Action Committee (HRAC) Group 15. We performed GC-MS/MS analysis of primary metabolites and LC-MS analysis of lipids in the herbicide-treated E. crus-galli, followed by Orthogonal Partial Least Squares Discriminant Analysis clustering. The results showed that dimesulfazet belongs to the HRAC Group 15 cluster. The endogenous concentrations of C24:0, C26:0, and C28:0 decreased in dimesulfazet-treated plants as compared to those in the control. Overall, the mode of action of dimesulfazet involves the inhibition of VLCFA biosynthesis.\n\n<img alt=\"\" src=\"https://www.jstage.jst.go.jp/pub/jpestics/advpub/0/advpub_D23-036/figure/advpub_D23-036.png\"/>\nFullsize Image","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"25 1","pages":""},"PeriodicalIF":1.5000,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pesticide Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1584/jpestics.d23-036","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENTOMOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Dimesulfazet can control annual and perennial sedges in rice paddies. Here we assessed its mode of action. We performed a phenotype assay of Arabidopsis, conducted a metabolomic analysis of Echinochloa crus-galli, and analyzed the endogenous concentration of very long-chain fatty acids (VLCFAs) in Schoenoplectiella juncoides. Dimesulfazet treatment caused curling and greening symptoms in the leaves and fiddlehead-like symptoms in the inflorescences of Arabidopsis. These symptoms were visually indistinguishable from those caused by flufenacet and benfuresate, which belong to Herbicide Resistance Action Committee (HRAC) Group 15. We performed GC-MS/MS analysis of primary metabolites and LC-MS analysis of lipids in the herbicide-treated E. crus-galli, followed by Orthogonal Partial Least Squares Discriminant Analysis clustering. The results showed that dimesulfazet belongs to the HRAC Group 15 cluster. The endogenous concentrations of C24:0, C26:0, and C28:0 decreased in dimesulfazet-treated plants as compared to those in the control. Overall, the mode of action of dimesulfazet involves the inhibition of VLCFA biosynthesis.

Fullsize Image

查看原文本刊更多论文

新型稻田除草剂 Dimesulfazet 是一种超长链脂肪酸生物合成抑制剂

Dimesulfazet 可以控制稻田中的一年生和多年生莎草。在此，我们对其作用模式进行了评估。我们对拟南芥进行了表型分析，对Echinochloa crus-galli进行了代谢组学分析，并对Schoenoplectiella juncoides中的内源性超长链脂肪酸（VLCFAs）浓度进行了分析。二甲磺草胺处理会导致拟南芥叶片出现卷曲和褪绿症状，花序出现萁状症状。这些症状与属于除草剂抗性行动委员会（HRAC）第 15 组的氟噻草胺和苯噻草胺造成的症状在视觉上没有区别。我们对经除草剂处理过的 E. crus-galli 进行了 GC-MS/MS 初级代谢物分析和 LC-MS 脂类分析，然后进行了正交偏最小二乘法判别分析聚类。结果表明，敌草快属于 HRAC 第 15 组。与对照组相比，二甲磺草胺处理过的植物中 C24:0、C26:0 和 C28:0 的内源浓度有所下降。总体而言，敌草快的作用模式涉及抑制 VLCFA 的生物合成。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Pesticide Science 农林科学-昆虫学

CiteScore

4.30

自引率

4.20%

发文量

审稿时长

18-36 weeks

期刊介绍： The Journal of Pesticide Science publishes the results of original research regarding the chemistry and biochemistry of pesticides including bio-based materials. It also covers their metabolism, toxicology, environmental fate and formulation.