Journal of Pesticide Science最新文献_第5页

Overview of Kenji Mori's pheromone synthesis series. 森健二信息素合成系列综述。

IF 2.4 4区农林科学

Journal of Pesticide Science Pub Date : 2023-02-20 DOI: 10.1584/jpestics.D22-062

Hirosato Takikawa, Shigefumi Kuwahara

引用次数: 0

Novel fungicide quinofumelin shows selectivity for fungal dihydroorotate dehydrogenase over the corresponding human enzyme. 新型杀菌剂喹诺芬林对真菌二氢乙酸脱氢酶的选择性优于相应的人酶。

IF 2.4 4区农林科学

Journal of Pesticide Science Pub Date : 2023-02-20 DOI: 10.1584/jpestics.D22-035

Norikazu Higashimura, Akira Hamada, Shinichi Banba

{"title":"Novel fungicide quinofumelin shows selectivity for fungal dihydroorotate dehydrogenase over the corresponding human enzyme.","authors":"Norikazu Higashimura, Akira Hamada, Shinichi Banba","doi":"10.1584/jpestics.D22-035","DOIUrl":"https://doi.org/10.1584/jpestics.D22-035","url":null,"abstract":"The species selectivity of class 2 dihydroorotate dehydrogenase (DHODH), a target enzyme for quinofumelin, was examined. The Homo sapiens DHODH (HsDHODH) assay system was developed to compare the selectivity of quinofumelin for fungi with that for mammals. The IC50 values of quinofumelin for Pyricularia oryzae DHODH (PoDHODH) and HsDHODH were 2.8 nM and >100 µM, respectively. Quinofumelin was highly selective for fungal over human DHODH. Additionally, we constructed recombinant P. oryzae mutants where PoDHODH (PoPYR4) or HsDHODH was inserted into the PoPYR4 disruption mutant. At quinofumelin concentration of 0.01-1 ppm, the PoPYR4 insertion mutants could not grow, but the HsDHODH gene-insertion mutants thrived. This indicates that HsDHODH is a substitute for PoDHODH, and quinofumelin could not inhibit HsDHODH as in the HsDHODH enzyme assay. Comparing the amino acid sequences of human and fungal DHODHs indicates that the significant difference at the ubiquinone-binding site contributes to the species selectivity of quinofumelin.","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"48 1","pages":"17-21"},"PeriodicalIF":2.4,"publicationDate":"2023-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b8/2c/jps-48-1-D22-035.PMC9978249.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10848679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and herbicidal activity of optically active cinmethylin, its enantiomer, and C3-substituted cinmethylin analogs. 旋光性辛甲基林及其对映体和c3取代辛甲基林类似物的合成及其除草活性。

IF 2.4 4区农林科学

Journal of Pesticide Science Pub Date : 2023-02-20 DOI: 10.1584/jpestics.D22-051

Narihito Ogawa, Shoya Toyoshima, Shinya Sekikawa, Masahiro Ishijima, Kyosuke Katagiri, Chihiro Uematsu, Tatsuya Hirano, Akihito Ootaka, Jun Suzuki

引用次数: 0

Design and biological activity of a novel fungicide, quinofumelin. 新型杀菌剂喹诺芬林的设计及生物活性研究。

IF 2.4 4区农林科学

Journal of Pesticide Science Pub Date : 2023-02-20 DOI: 10.1584/jpestics.D22-042

Hiroyuki Ito, Takeshi Takada, Munetsugu Morimoto, Hiroyuki Komai, Fumie Kajino, Toshiaki Ohara, Yasushi Tamagawa, Mikio Tsuda, Shinichi Banba

引用次数: 0

Quantitative evaluation of the biological activity of various brassinosteroids using spiral root induction in rice seeds 水稻螺旋根诱导对油菜素内酯生物活性的定量评价

4区农林科学

Journal of Pesticide Science Pub Date : 2023-01-01 DOI: 10.1584/jpestics.d23-044

Bunta Nishikawa, Kotaro Mori, Seisuke Takimoto, Bunta Watanabe, Midori Matsuo, Takeshi Nakano, Yoshiaki Nakagawa, Hisashi Miyagawa

引用次数: 0

Discovery of flometoquin, a novel quinoline insecticide 新型喹啉类杀虫剂氟美托昆的发现

4区农林科学

Journal of Pesticide Science Pub Date : 2023-01-01 DOI: 10.1584/jpestics.d23-035

Takeru Kobayashi, Hiroki Hotta, Takaaki Miyake, Masahiro Nomura, Ryo Horikoshi, Kazumi Yamamoto

引用次数: 0

Biological activities of nitromethylene analogues of imidacloprid with a 4,5-dimethylated imidazolidine ring 具有4,5-二甲基化咪唑烷环的咪氯啉亚甲基类似物的生物活性

4区农林科学

Journal of Pesticide Science Pub Date : 2023-01-01 DOI: 10.1584/jpestics.d23-024

Madoka Yamamura, Satoshi Yamauchi, Hisashi Nishiwaki

引用次数: 0

Identification of two phthalide derivatives and an oxindole compound isolated from the edible mushroom Pleurotus ostreatus and their inhibitory activities against plant pathogenic microorganisms 食用菌平菇(Pleurotus ostreatus</i&gt)中两个邻苯酞衍生物和一个氧化吲哚化合物的鉴定及其对植物病原微生物的抑制作用

4区农林科学

Journal of Pesticide Science Pub Date : 2023-01-01 DOI: 10.1584/jpestics.d23-039

Enrico M. Cabutaje, Kotomi Ueno, Kumiko Osaki-Oka, Kazutaka Kido, Thomas Edison E. dela Cruz, Atsushi Ishihara

{"title":"Identification of two phthalide derivatives and an oxindole compound isolated from the edible mushroom Pleurotus ostreatus and their inhibitory activities against plant pathogenic microorganisms","authors":"Enrico M. Cabutaje, Kotomi Ueno, Kumiko Osaki-Oka, Kazutaka Kido, Thomas Edison E. dela Cruz, Atsushi Ishihara","doi":"10.1584/jpestics.d23-039","DOIUrl":"https://doi.org/10.1584/jpestics.d23-039","url":null,"abstract":"The excessive use of chemical pesticides in agricultural fields for controlling plant pathogenic microorganisms harms human health, the environment, and other beneficial microorganisms in the soil and plants. To address this challenge, it is essential to isolate and discover bioactive compounds from biological resources that could inhibit plant pathogenic microorganisms. In this study, the culture filtrate of the edible mushroom Pleurotus ostreatus was subjected to bioassay-guided isolation, and two phthalide derivatives—4,6-dimethoxyphthalide (1) and 5,7-dimethoxyphthalide (2)—were identified, along with an oxindole compound—3-hydroxy-3-methyloxindole (3). The inhibitory activities of the three compounds were evaluated against four fungal and five bacterial pathogens. Remarkably, 1 and 2 exhibited the lowest IC50 values against the conidial germination and germ tube elongation of the rice blast fungus Pyricularia oryzae. However, their effectiveness against bacterial pathogens was relatively low. The (S) and (R)-enantiomers of 3-hydroxy-3-methyloxindole showed different activities against plant fungal pathogens and bacterial plant pathogens.","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"151 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135261860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A simulation model (PostPLANT-Soil) for predicting pesticide concentrations in succeeding leafy vegetables: I. Validation with experimental data in a Japanese Andosol field 预测后续叶菜中农药浓度的模拟模型(种植后-土壤):1 .日本安多索田间试验数据的验证

4区农林科学

Journal of Pesticide Science Pub Date : 2023-01-01 DOI: 10.1584/jpestics.d23-006

Keiya Inao, Sayuri Namiki, Yutaka Motoki, Nobuyasu Seike, Eiki Watanabe

{"title":"A simulation model (PostPLANT-Soil) for predicting pesticide concentrations in succeeding leafy vegetables: I. Validation with experimental data in a Japanese Andosol field","authors":"Keiya Inao, Sayuri Namiki, Yutaka Motoki, Nobuyasu Seike, Eiki Watanabe","doi":"10.1584/jpestics.d23-006","DOIUrl":"https://doi.org/10.1584/jpestics.d23-006","url":null,"abstract":"We developed a simulation model for predicting pesticide concentrations in succeeding leafy vegetables (PostPLANT-Soil), which includes the process of pesticide uptake from plant roots. To validate the model, we compared pesticide concentrations simulated by the model with values measured from field experiments in an upland Andosol. The model validation showed that pesticide concentrations in the plant shoot were correlated with the concentrations in the soil solution rather than those of the water-extracted pesticides. The model successfully simulated the concentration changes in plant shoots when the simulated concentrations of the pesticides in the soil solution were fitted to the measured values by considering the key parameter - the corrective coefficient for the soil adsorption coefficient. However, the simulated shoot concentrations at the appropriate harvest period exceeded the measured values. This indicates that the leafy vegetable used in this study may have some metabolic capacity for the pesticides.","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135600365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The structure–activity relationship of aryloxyacetylthioureas for the inhibition of Orobanche minor radicle elongation 芳基氧乙酰硫脲抑制小环切菌</i&gt的构效关系胚根伸长

4区农林科学

Journal of Pesticide Science Pub Date : 2023-01-01 DOI: 10.1584/jpestics.d23-034

Atsushi Okazawa, Shizuki Noda, Yusuke Mimura, Kotaro Fujino, Takatoshi Wakabayashi, Daisaku Ohta, Yukihiro Sugimoto, Motohiro Sonoda

{"title":"The structure–activity relationship of aryloxyacetylthioureas for the inhibition of Orobanche minor radicle elongation","authors":"Atsushi Okazawa, Shizuki Noda, Yusuke Mimura, Kotaro Fujino, Takatoshi Wakabayashi, Daisaku Ohta, Yukihiro Sugimoto, Motohiro Sonoda","doi":"10.1584/jpestics.d23-034","DOIUrl":"https://doi.org/10.1584/jpestics.d23-034","url":null,"abstract":"Orobanchaceae root parasitic weeds cause significant damage to agriculture and become threats to global food security. Integrated pest management is a key concept in modern agriculture and requires chemicals with various modes of action. Planteose accumulates as a storage carbohydrate in the dry seeds of root parasitic weeds. In Orobanche minor seeds, planteose is hydrolyzed by an α-galactosidase, OmAGAL2, during germination. It was found that the OmAGAL2 inhibitor, PI-28, suppressed the radicle elongation of germinating O. minor seeds. This inhibitory activity against O. minor radicle elongation was evaluated for a series of aryloxyacetylthioureas synthesized based on the structure of PI-28. Compounds with a 3-Cl or 4-Cl substituent on the benzene ring in the phenoxy moiety in PI-28 exhibited more potent activity than the parent PI-28. This is the first report on the effect of aryloxyacetylthioureas on a root parasitic weed and will contribute to the development of control reagents for root parasitic weeds.","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136304458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0