Ashraf Arif Nasir, Nurul Yaqin Syarif, Dzolkhifli Omar, Norhayu Asib
{"title":"Effectiveness of <i>Cordyceps fumosorosea</i> Wettable Powder Formulation against <i>Metisa plana</i> (Walker) and Its Side Effects on <i>Elaeidobius kamerunicus</i> in Oil palm Plantation.","authors":"Ashraf Arif Nasir, Nurul Yaqin Syarif, Dzolkhifli Omar, Norhayu Asib","doi":"10.1584/jpestics.D22-072","DOIUrl":"https://doi.org/10.1584/jpestics.D22-072","url":null,"abstract":"<p><p>Development of mycoinsecticides with <i>Cordyceps fumosorosea</i> as an active ingredient is established as an alternate way to control the <i>Metisa plana</i> population while reducing chemical insecticide dependence. Three mycoinsecticide formulations (SS6, SS7, and SS8) with dispersing and wetting agents were developed as wettable powder formulations in this trial. SS8 demonstrated the best wettability, suspensibility, and dispersibility with viability at 10<sup>7</sup> (CFU)/mL even after three months of storage. However, SS7 developed with <i>C. fumosorosea</i> as an active ingredient was found to effectively reduce the bagworm population by more than 95%. The application of all mycoinsecticide formulations in the infested oil palm area was able to reduce the <i>M. plana</i> population by more than 95%, 30 DAT. The formulations also show no significant increase in mortality of the oil palm pollinator, <i>Elaeidobius kamerunicus</i>. This finding indicates that the <i>C. fumosorosea</i> tested has potential for managing bagworms without harming pollinators on oil palm plantations.</p>","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"48 2","pages":"54-60"},"PeriodicalIF":2.4,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b0/9d/jps-48-2-D22-072.PMC10288000.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9714034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cycloprop-2-ene-1-carboxylates: Potential chemical biology tools in the early growth stage of <i>Arabidopsis thaliana</i>.","authors":"Tomoyuki Koyama, Ikuo Takahashi, Tadao Asami","doi":"10.1584/jpestics.D22-034","DOIUrl":"https://doi.org/10.1584/jpestics.D22-034","url":null,"abstract":"<p><p>Cyclopropene derivatives have been used as extremely reactive units in organic chemistry owing to their high ring-strain energy. They have become popular reagents both for bioorthogonal chemistry and for chemical biology because of their small size and ability to be genetically encoded. In this context, we conducted an exploratory study to identify the biologically active cyclopropenes that affect normal plant growth. We synthesized several cycloprop-2-ene-1-carboxylic acid derivatives and evaluated their effects on the early growth stage of <i>Arabidopsis thaliana</i>. Eventually, we identified the chemicals that affect apical hook development in <i>Arabidopsis thaliana</i>. Their mode of action is different from those of ethylene receptor inhibition and gibberellin biosynthesis inhibition. We expect that some of the chemicals reported here can be new tools in chemical biology to determine useful molecular targets for herbicides or plant growth regulators.</p>","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"48 2","pages":"61-64"},"PeriodicalIF":2.4,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/34/6a/jps-48-2-D22-034.PMC10288001.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9714035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fungicidal spectrum and biological properties of a new fungicide, pyriofenone.","authors":"Munekazu Ogawa, Akihiro Nishimura, Yuzuka Abe, Yohei Fukumori, Kazumi Suzuki, Shigeru Mitani","doi":"10.1584/jpestics.D22-068","DOIUrl":"https://doi.org/10.1584/jpestics.D22-068","url":null,"abstract":"<p><p>Pyriofenone is a new fungicide developed by Ishihara Sangyo Kaisha, Ltd. To determine the fungicidal spectrum of pyriofenone, <i>in vivo</i> pot tests and <i>in vitro</i> mycelial growth-inhibition tests were conducted. Pyriofenone showed excellent activity against wheat and cucumber powdery mildew and moderate efficacy against rice blast in the pot tests. In the mycelial growth-inhibition tests, most fungi were not affected by pyriofenone except for <i>Botrytis cinerea</i>, <i>Helminthosporium sacchari</i>, <i>Pseudocercosporella herpotrichoides</i>, <i>Pyricularia oryzae</i>, <i>Rosellinia necatrix</i>, and <i>Verticillium dahliae</i>. The fungicidal properties of pyriofenone on powdery mildew in cucumber and wheat were evaluated precisely. Pyriofenone exhibited excellent preventive and residual activities. It had high rainfastness in the cucumber leaves against powdery mildew. Pyriofenone also showed inhibitory activity on lesion development upon application until 2 days after inoculation, and the lesion expansion and sporulation of the cucumber powdery mildew fungus were effectively controlled. Furthermore, pyriofenone showed translaminar and vapor activities.</p>","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"48 2","pages":"65-70"},"PeriodicalIF":2.4,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/25/0e/jps-48-2-D22-068.PMC10288004.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10045367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Visualization of azoxystrobin penetration in wheat leaves using mass microscopy imaging.","authors":"Soichiro Ikuta, Eiichiro Fukusaki, Shuichi Shimma","doi":"10.1584/jpestics.D22-063","DOIUrl":"https://doi.org/10.1584/jpestics.D22-063","url":null,"abstract":"<p><p>Fungicides must penetrate the internal tissues of plants to kill pathogenic fungi. Mass spectrometers have been used to confirm this penetration, but conventional mass spectrometric methods cannot distinguish the fungicides in different internal tissues owing to the extraction steps. However, matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) can detect the penetration of fungicides into leaf sections through direct analysis of the sample surfaces. Therefore, the objective of this study was to establish a method for visualizing fungicide penetration in wheat leaf cross sections using MALDI-MSI. The penetration of azoxystrobin from the epidermal to the internal tissue of the leaves was observed. Moreover, azoxystrobin accumulates in the cells around the vascular bundle. This study suggests that MSI can be useful for the evaluation of fungicide penetration in plant leaves.</p>","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"48 2","pages":"29-34"},"PeriodicalIF":2.4,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d1/17/jps-48-2-D22-063.PMC10288002.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9707130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Overview of Kenji Mori's pheromone synthesis series.","authors":"Hirosato Takikawa, Shigefumi Kuwahara","doi":"10.1584/jpestics.D22-062","DOIUrl":"https://doi.org/10.1584/jpestics.D22-062","url":null,"abstract":"<p><p>It was the late Professor Kenji Mori, the giant of pheromone synthesis and pioneer of pheromone stereochemistry, who laid the foundation for the practical application of insect pheromones, which play an important role in Integrated Pest Management, one of the key concepts of agriculture in the 21st century. Therefore, it would be meaningful to retrace his achievements at this time, three and a half years after his death. In this review, we would like to introduce some of his notable synthetic studies from his <i>Pheromone Synthesis Series</i> and reconfirm his contributions to the development of pheromone chemistry and their impacts on natural science.</p>","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"48 1","pages":"1-10"},"PeriodicalIF":2.4,"publicationDate":"2023-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978250/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9186125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Novel fungicide quinofumelin shows selectivity for fungal dihydroorotate dehydrogenase over the corresponding human enzyme.","authors":"Norikazu Higashimura, Akira Hamada, Shinichi Banba","doi":"10.1584/jpestics.D22-035","DOIUrl":"https://doi.org/10.1584/jpestics.D22-035","url":null,"abstract":"<p><p>The species selectivity of class 2 dihydroorotate dehydrogenase (DHODH), a target enzyme for quinofumelin, was examined. The <i>Homo sapiens</i> DHODH (HsDHODH) assay system was developed to compare the selectivity of quinofumelin for fungi with that for mammals. The IC<sub>50</sub> values of quinofumelin for <i>Pyricularia oryzae</i> DHODH (PoDHODH) and HsDHODH were 2.8 nM and >100 µM, respectively. Quinofumelin was highly selective for fungal over human DHODH. Additionally, we constructed recombinant <i>P. oryzae</i> mutants where <i>PoDHODH</i> (<i>PoPYR4</i>) or <i>HsDHODH</i> was inserted into the <i>PoPYR4</i> disruption mutant. At quinofumelin concentration of 0.01-1 ppm, the <i>PoPYR4</i> insertion mutants could not grow, but the <i>HsDHODH</i> gene-insertion mutants thrived. This indicates that HsDHODH is a substitute for PoDHODH, and quinofumelin could not inhibit HsDHODH as in the HsDHODH enzyme assay. Comparing the amino acid sequences of human and fungal DHODHs indicates that the significant difference at the ubiquinone-binding site contributes to the species selectivity of quinofumelin.</p>","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"48 1","pages":"17-21"},"PeriodicalIF":2.4,"publicationDate":"2023-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b8/2c/jps-48-1-D22-035.PMC9978249.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10848679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synthesis and herbicidal activity of optically active cinmethylin, its enantiomer, and C3-substituted cinmethylin analogs.","authors":"Narihito Ogawa, Shoya Toyoshima, Shinya Sekikawa, Masahiro Ishijima, Kyosuke Katagiri, Chihiro Uematsu, Tatsuya Hirano, Akihito Ootaka, Jun Suzuki","doi":"10.1584/jpestics.D22-051","DOIUrl":"https://doi.org/10.1584/jpestics.D22-051","url":null,"abstract":"<p><p>We investigated the synthesis and herbicidal activity of optically active cinmethylin, its enantiomer, and C3-substituted cinmethylin analogs. Optically active cinmethylin could be obtained in seven steps with the Sharpless asymmetric dihydroxylation of α-terpinene. The synthesized cinmethylin and its enantiomer showed similar herbicidal activity, which was independent of the stereochemistry. Next, we synthesized cinmethylin analogs with various substituents at the C3 position. We found that analogs with methylene, oxime, ketone, or methyl groups at the C3 position show excellent herbicidal activity.</p>","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"48 1","pages":"11-16"},"PeriodicalIF":2.4,"publicationDate":"2023-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5b/d0/jps-48-1-D22-051.PMC9978247.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9100232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Design and biological activity of a novel fungicide, quinofumelin.","authors":"Hiroyuki Ito, Takeshi Takada, Munetsugu Morimoto, Hiroyuki Komai, Fumie Kajino, Toshiaki Ohara, Yasushi Tamagawa, Mikio Tsuda, Shinichi Banba","doi":"10.1584/jpestics.D22-042","DOIUrl":"https://doi.org/10.1584/jpestics.D22-042","url":null,"abstract":"<p><p>Developed by Mitsui Chemicals Agro, Inc. (Tokyo, Japan), quinofumelin is a novel fungicide with a distinct chemical structure including 3-(isoquinolin-1-yl) quinoline, demonstrating fungicidal activity against a variety of fungi, including rice blast and gray mold. We screened our compound library to identify curative compounds for rice blast and evaluated the effect of fungicide-resistant strains of gray mold. Our research demonstrated that quinofumelin has curative effects against rice blast and is not cross-resistant to existing fungicides. Accordingly, the use of quinofumelin can be considered a novel approach for disease control in agricultural production. In this report, the discovery of quinofumelin from the initial compound is described in detail.</p>","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"48 1","pages":"22-27"},"PeriodicalIF":2.4,"publicationDate":"2023-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/88/41/jps-48-1-D22-042.PMC9978248.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9100233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quantitative evaluation of the biological activity of various brassinosteroids using spiral root induction in rice seeds","authors":"Bunta Nishikawa, Kotaro Mori, Seisuke Takimoto, Bunta Watanabe, Midori Matsuo, Takeshi Nakano, Yoshiaki Nakagawa, Hisashi Miyagawa","doi":"10.1584/jpestics.d23-044","DOIUrl":"https://doi.org/10.1584/jpestics.d23-044","url":null,"abstract":"Spiral roots are induced in germinated rice seeds through treatment with nanomolar brassinosteroids (BRs) but not with other plant hormones. Here, we determined the minimum effective concentration (MEC) of various BRs to induce spiral roots in germinated rice seeds. The reciprocal logarithm of MEC, pMEC, was used as the BL-like activity index, which was linearly correlated with the reciprocal logarithm of a 50% effective dose (pED50) as evaluated in the rice lamina inclination assay. Furthermore, a ligand-receptor docking simulation was performed against the BL receptor complex, Arabidopsis thaliana BRI1/SERK1, and the binding free energy (ΔGbind) was calculated for the tested BRs. The ΔGbind calculation was performed using the molecular mechanics/generalized Born surface area method on an ensemble of uncorrelated snapshots collected via molecular dynamics to predict biological activity.","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135710793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Discovery of flometoquin, a novel quinoline insecticide","authors":"Takeru Kobayashi, Hiroki Hotta, Takaaki Miyake, Masahiro Nomura, Ryo Horikoshi, Kazumi Yamamoto","doi":"10.1584/jpestics.d23-035","DOIUrl":"https://doi.org/10.1584/jpestics.d23-035","url":null,"abstract":"Flometoquin, 2-ethyl-3,7-dimethyl-6-[4-(trifluoromethoxy)phenoxy]quinolin-4-yl methyl carbonate, is a novel insecticide with a structurally unique phenoxy-quinoline. It was discovered in 2004 by the collaborative research of Nippon Kayaku and Meiji Seika Kaisha, Ltd. (currently, Mitsui Chemicals Crop & Life Solutions, Inc.). The compound demonstrates strong and quick insecticidal action against a variety of thrips species at the nymphal and adult stages through contact and feeding activity, which could minimize crop damage and economic loss by insect pest species. In addition, flometoquin is safe for tested non-target arthropods, which makes it suitable for controlling the insect pests mentioned above under Integrated Pest Management (IPM) programs. Here, we describe a structure–activity relationship study from lead generation to the discovery of flometoquin and its insecticidal properties, including knockdown activity and effects against non-targeted arthropods.","PeriodicalId":16712,"journal":{"name":"Journal of Pesticide Science","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135710796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}